| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1020790654 |
| P356 | DOI | 10.1007/S00109-014-1156-Z |
| P932 | PMC publication ID | 4083097 |
| P698 | PubMed publication ID | 24777637 |
| P2093 | author name string | Fan Pan | |
| Joseph Barbi | |||
| P2860 | cites work | Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells | Q78806915 |
| TNF receptor-associated factor 6 deficiency during hemopoiesis induces Th2-polarized inflammatory disease | Q79317461 | ||
| TLR engagement prevents transplantation tolerance | Q80256970 | ||
| Itch E3 ligase-mediated regulation of TGF-beta signaling by modulating smad2 phosphorylation | Q80531690 | ||
| Differential but direct abolishment of human regulatory T cell suppressive capacity by various TLR2 ligands | Q83986858 | ||
| Cbl-b(-/-) T cells demonstrate in vivo resistance to regulatory T cells but a context-dependent resistance to TGF-beta | Q84563082 | ||
| Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions | Q22010047 | ||
| Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function | Q24317859 | ||
| Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1 | Q24336199 | ||
| Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes | Q24645701 | ||
| CHIP promotes Runx2 degradation and negatively regulates osteoblast differentiation | Q24656900 | ||
| Ubiquitin in the immune system | Q26998711 | ||
| PKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytes | Q27320965 | ||
| Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells | Q27860460 | ||
| The ubiquitin system | Q27860803 | ||
| Foxp3 protein stability is regulated by cyclin-dependent kinase 2 | Q28117202 | ||
| The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3 | Q28118511 | ||
| Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis | Q28118730 | ||
| Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases | Q28131652 | ||
| Breaking the chains: structure and function of the deubiquitinases | Q28131738 | ||
| The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases | Q28139237 | ||
| Protein degradation by the ubiquitin-proteasome pathway in normal and disease states | Q28243121 | ||
| Modification of proteins by ubiquitin and ubiquitin-like proteins | Q28244250 | ||
| Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia | Q28267951 | ||
| A genomic and functional inventory of deubiquitinating enzymes | Q28284911 | ||
| The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity | Q28505401 | ||
| The tumor suppressor CYLD controls the function of murine regulatory T cells | Q28505871 | ||
| Characteristics and biological functions of TRAF6 | Q28586696 | ||
| Dependence of self-tolerance on TRAF6-directed development of thymic stroma | Q28590193 | ||
| The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1 | Q28591890 | ||
| E3 ubiquitin ligase GRAIL controls primary T cell activation and oral tolerance | Q28750747 | ||
| How regulatory T cells work | Q29614262 | ||
| Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation | Q29614840 | ||
| Regulatory T cells and immune tolerance | Q29616864 | ||
| Molecular antagonism and plasticity of regulatory and inflammatory T cell programs | Q29619478 | ||
| USP18 inhibits NF-κB and NFAT activation during Th17 differentiation by deubiquitinating the TAK1-TAB1 complex | Q37055514 | ||
| Pathophysiology of adult obstructive sleep apnea. | Q37066450 | ||
| Differential requirement of PKC-theta in the development and function of natural regulatory T cells | Q37236962 | ||
| Itch expression by Treg cells controls Th2 inflammatory responses. | Q37259247 | ||
| TLR4 signaling via MyD88 and TRIF differentially shape the CD4+ T cell response to Porphyromonas gingivalis hemagglutinin B | Q37259689 | ||
| Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo | Q37312884 | ||
| The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR. | Q37319760 | ||
| Differential requirement for CARMA1 in agonist-selected T-cell development | Q37353796 | ||
| Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation | Q37358144 | ||
| Antigen-specific induced T regulatory cells impair dendritic cell function via an IL-10/MARCH1-dependent mechanism | Q37381562 | ||
| Developmental plasticity of Th17 and Treg cells. | Q37518502 | ||
| Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response | Q37552169 | ||
| Noncanonical K27-linked polyubiquitination of TIEG1 regulates Foxp3 expression and tumor growth. | Q37556159 | ||
| Stability of regulatory T-cell lineage. | Q37961172 | ||
| An essential role of the transcription factor GATA-3 for the function of regulatory T cells | Q38586280 | ||
| STUB1 is essential for T-cell activation by ubiquitinating CARMA1. | Q39209790 | ||
| Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization. | Q39765588 | ||
| Cutting edge: deficiency in the E3 ubiquitin ligase Cbl-b results in a multifunctional defect in T cell TGF-beta sensitivity in vitro and in vivo | Q40327455 | ||
| The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation | Q41762357 | ||
| An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos. | Q41819445 | ||
| Analysis of the T-cell receptor repertoires of tumor-infiltrating conventional and regulatory T cells reveals no evidence for conversion in carcinogen-induced tumors | Q41852491 | ||
| Cutting edge: Receptors for C3a and C5a modulate stability of alloantigen-reactive induced regulatory T cells. | Q41889471 | ||
| Stability of the regulatory T cell lineage in vivo. | Q42060265 | ||
| Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells | Q42196147 | ||
| Convergences and divergences of thymus- and peripherally derived regulatory T cells in cancer | Q42571627 | ||
| Protein kinase C-theta mediates negative feedback on regulatory T cell function | Q42728050 | ||
| Degradation of proto-oncoprotein c-Rel by the ubiquitin-proteasome pathway | Q42823633 | ||
| The treg/th17 imbalance in patients with obstructive sleep apnoea syndrome | Q42847879 | ||
| Resistance to CD4+CD25+ regulatory T cells and TGF-beta in Cbl-b-/- mice | Q44240372 | ||
| Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor. | Q44338643 | ||
| Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis | Q44688981 | ||
| TRAF6 directs commitment to regulatory T cells in thymocytes | Q45356807 | ||
| Canonical Wnt signaling negatively modulates regulatory T cell function. | Q45847463 | ||
| Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo. | Q46223676 | ||
| Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor | Q47740353 | ||
| Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance | Q47817407 | ||
| Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells. | Q50958644 | ||
| Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells. | Q50968365 | ||
| TLR2 stimulation drives human naive and effector regulatory T cells into a Th17-like phenotype with reduced suppressive function. | Q50999206 | ||
| Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions. | Q51765584 | ||
| Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells. | Q51908453 | ||
| Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. | Q51997055 | ||
| Dynamic regulation of Th17 differentiation by oxygen concentrations. | Q54539948 | ||
| c-Rel is crucial for the induction of Foxp3(+) regulatory CD4(+) T cells but not T(H)17 cells. | Q54562195 | ||
| Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b | Q59058408 | ||
| c-Rel but not NF-κB1 is important for T regulatory cell development | Q61628000 | ||
| Cutting Edge: Trans-Signaling via the Soluble IL-6R Abrogates the Induction of FoxP3 in Naive CD4+CD25- T Cells | Q62658842 | ||
| HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells | Q35102340 | ||
| SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-{gamma} and IL-17A production | Q35237530 | ||
| GATA3 controls Foxp3⁺ regulatory T cell fate during inflammation in mice | Q35484886 | ||
| The deubiquitinase CYLD targets Smad7 protein to regulate transforming growth factor β (TGF-β) signaling and the development of regulatory T cells | Q35562497 | ||
| Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses | Q35748571 | ||
| CpG DNA inhibits CD4+CD25+ Treg suppression through direct MyD88-dependent costimulation of effector CD4+ T cells | Q35776179 | ||
| TNF downmodulates the function of human CD4+CD25hi T-regulatory cells | Q35849817 | ||
| CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt | Q35916665 | ||
| Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency | Q35992006 | ||
| Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells | Q35992433 | ||
| Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells | Q35995214 | ||
| Inhibition of S-phase kinase-associated protein 2 (Skp2) reprograms and converts diabetogenic T cells to Foxp3+ regulatory T cells | Q36066458 | ||
| An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes | Q36067669 | ||
| STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease. | Q36231545 | ||
| Regulating the regulators: control of protein ubiquitination and ubiquitin-like modifications by extracellular stimuli | Q36246889 | ||
| Absence of MyD88 signaling induces donor-specific kidney allograft tolerance | Q36280335 | ||
| The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology | Q36336588 | ||
| Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa | Q36339991 | ||
| Extrathymically generated regulatory T cells control mucosal TH2 inflammation | Q36359813 | ||
| The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells | Q36509846 | ||
| Aiolos promotes TH17 differentiation by directly silencing Il2 expression | Q36520966 | ||
| High TCR stimuli prevent induced regulatory T cell differentiation in a NF-κB-dependent manner | Q36530189 | ||
| An obligate cell-intrinsic function for CD28 in Tregs | Q36580415 | ||
| Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells | Q36603536 | ||
| T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR. | Q36693820 | ||
| Identification of the E3 deubiquitinase ubiquitin-specific peptidase 21 (USP21) as a positive regulator of the transcription factor GATA3 | Q36725079 | ||
| TGF-beta and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3. | Q36893657 | ||
| A new look at T cell receptor signaling to nuclear factor-κB | Q36906449 | ||
| MARCH1-mediated MHCII ubiquitination promotes dendritic cell selection of natural regulatory T cells | Q36907903 | ||
| Generation and function of induced regulatory T cells | Q36938160 | ||
| Hypoxia-inducible factor 1 (HIF-1) pathway | Q36966537 | ||
| A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells | Q36974721 | ||
| T cell activation threshold regulated by E3 ubiquitin ligase Cbl-b determines fate of inducible regulatory T cells | Q36986111 | ||
| Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways | Q37011956 | ||
| Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation | Q29620116 | ||
| Regulatory T cells: mechanisms of differentiation and function | Q29620731 | ||
| Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells. | Q30168616 | ||
| Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery | Q33414811 | ||
| c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells | Q33590483 | ||
| Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome | Q33596681 | ||
| Inhibition of TLR4 signaling prolongs Treg-dependent murine islet allograft survival | Q33598788 | ||
| Hsp70 and CHIP selectively mediate ubiquitination and degradation of hypoxia-inducible factor (HIF)-1alpha but Not HIF-2alpha | Q33662015 | ||
| Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells | Q33810601 | ||
| Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses | Q33830564 | ||
| TLR2-dependent induction of IL-10 and Foxp3+ CD25+ CD4+ regulatory T cells prevents effective anti-tumor immunity induced by Pam2 lipopeptides in vivo | Q33886184 | ||
| Rapid temporal control of Foxp3 protein degradation by sirtuin-1. | Q33886284 | ||
| Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate | Q33908130 | ||
| TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2. | Q33931833 | ||
| Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells | Q33979948 | ||
| The E3 ubiquitin ligase GRAIL regulates T cell tolerance and regulatory T cell function by mediating T cell receptor-CD3 degradation. | Q34041946 | ||
| Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity. | Q34049065 | ||
| c-Rel controls multiple discrete steps in the thymic development of Foxp3+ CD4 regulatory T cells | Q34069619 | ||
| Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells. | Q34086998 | ||
| Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells. | Q34088521 | ||
| Optimal population of FoxP3+ T cells in tumors requires an antigen priming-dependent trafficking receptor switch | Q34146406 | ||
| Toll-like receptor 2 controls expansion and function of regulatory T cells | Q34264024 | ||
| GITR pathway activation abrogates tumor immune suppression through loss of regulatory T cell lineage stability | Q34397451 | ||
| Convergence of Itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation | Q34468354 | ||
| CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation. | Q34501441 | ||
| Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells | Q34557118 | ||
| GRAIL is up-regulated in CD4+ CD25+ T regulatory cells and is sufficient for conversion of T cells to a regulatory phenotype | Q34607035 | ||
| Engagement of TLR2 does not reverse the suppressor function of mouse regulatory T cells, but promotes their survival | Q34611787 | ||
| Cutting edge: CD28 and c-Rel-dependent pathways initiate regulatory T cell development. | Q34617728 | ||
| Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis. | Q34655006 | ||
| Control of regulatory T cell lineage commitment and maintenance | Q34658594 | ||
| TRAF6 is essential for maintenance of regulatory T cells that suppress Th2 type autoimmunity | Q34994847 | ||
| IL-2 controls the stability of Foxp3 expression in TGF-beta-induced Foxp3+ T cells in vivo | Q34995596 | ||
| TLR2 signaling improves immunoregulation to prevent type 1 diabetes | Q34999656 | ||
| P433 | issue | 6 | |
| P304 | page(s) | 555-569 | |
| P577 | publication date | 2014-04-29 | |
| P1433 | published in | Journal of Molecular Medicine | Q6295593 |
| P1476 | title | Ubiquitous points of control over regulatory T cells | |
| P478 | volume | 92 |
| Q35944514 | Missed, Not Missing: Phylogenomic Evidence for the Existence of Avian FoxP3. |
| Q38582873 | Physiological, Tumor, and Metastatic Niches: Opportunities and Challenges for Targeting the Tumor Microenvironment |
| Q91868488 | T Regulatory Cells From Non-obese Diabetic Mice Show Low Responsiveness to IL-2 Stimulation and Exhibit Differential Expression of Anergy-Related and Ubiquitination Factors |
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