| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2012PNAS..109E2784C |
| P356 | DOI | 10.1073/PNAS.1202366109 |
| P932 | PMC publication ID | 3478644 |
| P698 | PubMed publication ID | 22988108 |
| P5875 | ResearchGate publication ID | 230871899 |
| P50 | author | John Cambier | Q28112855 |
| Eóin N McNamee | Q42582545 | ||
| Edwin F de Zoeten | Q57345364 | ||
| Louise E Glover | Q57730904 | ||
| Eric L Campbell | Q58699569 | ||
| Joseph A Westrich | Q59694074 | ||
| P2093 | author name string | Holger K Eltzschig | |
| Kurt R Stenmark | |||
| Sean P Colgan | |||
| Eric T Clambey | |||
| Paul Jedlicka | |||
| P2860 | cites work | TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function | Q24314628 |
| Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1 | Q24336199 | ||
| The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo | Q24600773 | ||
| Endothelial CD47 interaction with SIRPgamma is required for human T-cell transendothelial migration under shear flow conditions in vitro | Q24645039 | ||
| Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors | Q24672615 | ||
| Th17 and regulatory T cells in mediating and restraining inflammation | Q27687428 | ||
| Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells | Q27860460 | ||
| Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors | Q28268052 | ||
| The reno-vascular A2B adenosine receptor protects the kidney from ischemia | Q28473410 | ||
| Vhlh gene deletion induces Hif-1-mediated cell death in thymocytes | Q28504459 | ||
| Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression | Q29615344 | ||
| Molecular antagonism and plasticity of regulatory and inflammatory T cell programs | Q29619478 | ||
| A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells. | Q30440525 | ||
| Targeted deletion of HIF-1alpha gene in T cells prevents their inhibition in hypoxic inflamed tissues and improves septic mice survival | Q33297014 | ||
| Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease | Q33402434 | ||
| Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection | Q33624096 | ||
| Metabolic shifts in immunity and inflammation. | Q33829813 | ||
| Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses | Q33830564 | ||
| Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate | Q33908130 | ||
| Hypoxia inducible factor 1 alpha regulates T cell receptor signal transduction. | Q34144632 | ||
| Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells | Q34189120 | ||
| The adenosine/neutrophil paradox resolved: human neutrophils possess both A1 and A2 receptors that promote chemotaxis and inhibit O2 generation, respectively | Q34248005 | ||
| Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production | Q34248310 | ||
| Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells | Q34299001 | ||
| The resurgence of A2B adenosine receptor signaling | Q34307284 | ||
| Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD. | Q34457199 | ||
| The role of the transcription factor Foxp3 in the development of regulatory T cells | Q34569892 | ||
| Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces | Q34590015 | ||
| Control of regulatory T cell lineage commitment and maintenance | Q34658594 | ||
| CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner. | Q35006074 | ||
| HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells | Q35102340 | ||
| Foxp3+ follicular regulatory T cells control the germinal center response. | Q35239023 | ||
| The Th17 immune response is controlled by the Rel-RORγ-RORγ T transcriptional axis | Q35441559 | ||
| GATA3 controls Foxp3⁺ regulatory T cell fate during inflammation in mice | Q35484886 | ||
| An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes | Q36067669 | ||
| Tuning microenvironments: induction of regulatory T cells by dendritic cells | Q36151935 | ||
| Altering the distribution of Foxp3(+) regulatory T cells results in tissue-specific inflammatory disease | Q36229433 | ||
| JAM-A regulates permeability and inflammation in the intestine in vivo | Q36294373 | ||
| Mucosal protection by hypoxia-inducible factor prolyl hydroxylase inhibition. | Q36372667 | ||
| T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR. | Q36693820 | ||
| Molecular mechanisms regulating TGF-beta-induced Foxp3 expression | Q36905445 | ||
| A protective function for interleukin 17A in T cell-mediated intestinal inflammation | Q37260173 | ||
| Epigenetic mechanisms of regulation of Foxp3 expression | Q37412329 | ||
| Ischemia and reperfusion--from mechanism to translation | Q37455225 | ||
| Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells | Q37474900 | ||
| Oxygen homeostasis | Q37788021 | ||
| Hypoxia and inflammation | Q37842498 | ||
| The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells | Q38336873 | ||
| An essential role of the transcription factor GATA-3 for the function of regulatory T cells | Q38586280 | ||
| Hypoxia enhances cancer cell invasion through relocalization of the proprotein convertase furin from the trans-Golgi network to the cell surface | Q39556460 | ||
| Synovial tissue hypoxia and inflammation in vivo | Q39708042 | ||
| Hypoxia-inducible factor-dependent repression of equilibrative nucleoside transporter 2 attenuates mucosal inflammation during intestinal hypoxia | Q39902165 | ||
| Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis. | Q40176806 | ||
| Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression. | Q40260497 | ||
| Hypoxia-enhanced expression of the proprotein convertase furin is mediated by hypoxia-inducible factor-1: impact on the bioactivation of proproteins. | Q40478703 | ||
| Differential regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1 alpha in activated T lymphocytes | Q40774554 | ||
| The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation | Q41762357 | ||
| Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions | Q41911767 | ||
| Molecular mechanisms underlying FOXP3 induction in human T cells | Q42491664 | ||
| Hypoxia upregulates the synthesis of TGF-beta 1 by human dermal fibroblasts | Q44176698 | ||
| Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1alpha | Q44948359 | ||
| T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response | Q45292627 | ||
| Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia. | Q46175545 | ||
| Hypoxia-inducible factor-1 is central to cardioprotection: a new paradigm for ischemic preconditioning | Q46509525 | ||
| TCR engagement increases hypoxia-inducible factor-1 alpha protein synthesis via rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells | Q46535400 | ||
| HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak | Q46726814 | ||
| The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis. | Q46827571 | ||
| Deacetylase inhibition promotes the generation and function of regulatory T cells. | Q46961808 | ||
| Cutting edge: hypoxia-inducible factor 1alpha and its activation-inducible short isoform I.1 negatively regulate functions of CD4+ and CD8+ T lymphocytes | Q79174323 | ||
| Regulatory T cells dynamically control the primary immune response to foreign antigen | Q79803360 | ||
| Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions | Q94028943 | ||
| P433 | issue | 41 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | inflammation | Q101991 |
| hypoxia | Q105688 | ||
| P304 | page(s) | E2784-93 | |
| P577 | publication date | 2012-09-17 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa | |
| P478 | volume | 109 |
| Q26749571 | A Metabolic Immune Checkpoint: Adenosine in Tumor Microenvironment |
| Q35157591 | A novel oxygen carrier "YQ23" suppresses the liver tumor metastasis by decreasing circulating endothelial progenitor cells and regulatory T cells. |
| Q90114851 | Aberrations in Notch-Hedgehog signalling reveal cancer stem cells harbouring conserved oncogenic properties associated with hypoxia and immunoevasion |
| Q37468682 | Adenosine A2A receptor (A2AR) is a fine-tune regulator of the collagen1:collagen3 balance |
| Q92511975 | An analysis of Treg/Th17 cells imbalance associated microRNA networks regulated by moxibustion therapy on Zusanli (ST36) and Shenshu (BL23) in mice with collagen induced arthritis |
| Q41080205 | Anti-Inflammatory Effects of Hyperbaric Oxygenation during DSS-Induced Colitis in BALB/c Mice Include Changes in Gene Expression of HIF-1α, Proinflammatory Cytokines, and Antioxidative Enzymes. |
| Q37310622 | Antiangiogenic therapy using endostatin increases the number of ALDH+ lung cancer stem cells by generating intratumor hypoxia |
| Q49546319 | Antitumor T cell reconditioning: improving metabolic fitness for optimal cancer immunotherapy |
| Q27006863 | Attenuating myocardial ischemia by targeting A2B adenosine receptors |
| Q91954814 | Blocking Triggering Receptor Expressed on Myeloid Cells-1-Positive Tumor-Associated Macrophages Induced by Hypoxia Reverses Immunosuppression and Anti-Programmed Cell Death Ligand 1 Resistance in Liver Cancer |
| Q36860320 | CD73+ regulatory T cells contribute to adenosine-mediated resolution of acute lung injury. |
| Q98291350 | Cancer Cell Metabolism Bolsters Immunotherapy Resistance by Promoting an Immunosuppressive Tumor Microenvironment |
| Q89748367 | Carbonic anhydrase 9 (CA9) expression in non-small-cell lung cancer: correlation with regulatory FOXP3+T-cell tumour stroma infiltration |
| Q36789958 | Cell surface Glut1 levels distinguish human CD4 and CD8 T lymphocyte subsets with distinct effector functions |
| Q38433996 | Cellular and molecular mechanisms of inflammation-induced angiogenesis |
| Q49788493 | Chemotherapy induces enrichment of CD47+/CD73+/PDL1+ immune evasive triple-negative breast cancer cells |
| Q28069832 | Clinical Potential of Regulatory T Cell Therapy in Liver Diseases: An Overview and Current Perspectives |
| Q59789588 | Copper-Fructose Interactions: A Novel Mechanism in the Pathogenesis of NAFLD |
| Q40504112 | Deficiency of HIF1α in Antigen-Presenting Cells Aggravates Atherosclerosis and Type 1 T-Helper Cell Responses in Mice. |
| Q35138124 | Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo |
| Q39241653 | Determinants of hypoxia inducible factor (HIF) activity in the intestinal mucosa |
| Q50080787 | Dimethyloxalylglycine preserves the intestinal microvasculature and protects against intestinal injury in a neonatal mouse NEC model: role of VEGF signaling |
| Q35837701 | E3 Ubiquitin Ligase VHL Regulates Hypoxia-Inducible Factor-1α to Maintain Regulatory T Cell Stability and Suppressive Capacity. |
| Q91640109 | EGFR-AS1/HIF2A regulates the expression of FOXP3 to impact the cancer stemness of smoking-related non-small cell lung cancer |
| Q38984496 | Effect of HIF1α on Foxp3 expression in CD4+ CD25- T lymphocytes |
| Q36014258 | Effects of hypoxia and its relationship with apoptosis, stem cells, and angiogenesis on the thymus of children with congenital heart defects: a morphological and immunohistochemical study |
| Q91130183 | Effects of oxygen levels and a Lactobacillus plantarum strain on mortality and immune response of chickens at high altitude |
| Q59809040 | Effects of tumor metabolic microenvironment on regulatory T cells |
| Q26775176 | Emerging Roles for MicroRNAs in Perioperative Medicine |
| Q36476035 | Endogenous adaptation to low oxygen modulates T-cell regulatory pathways in EAE. |
| Q102152125 | Endogenous antisense RNA curbs CD39 expression in Crohn's disease |
| Q33878542 | Extracellular adenosine-mediated modulation of regulatory T cells |
| Q41846265 | Fatty Acid Biosynthesis Inhibition Increases Reduction Potential in Neuronal Cells under Hypoxia |
| Q38931576 | Fatty acid biosynthesis from glutamate and glutamine is specifically induced in neuronal cells under hypoxia |
| Q90632881 | Forkhead Box P3 Methylation and Expression in Men with Obstructive Sleep Apnea |
| Q27025284 | Fueling immunity: insights into metabolism and lymphocyte function |
| Q100316586 | Functional CRISPR dissection of gene networks controlling human regulatory T cell identity |
| Q39920027 | Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans |
| Q34515298 | Genome Resequencing Identifies Unique Adaptations of Tibetan Chickens to Hypoxia and High-Dose Ultraviolet Radiation in High-Altitude Environments |
| Q35137138 | HIF transcription factors, inflammation, and immunity |
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| Q64083937 | HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma |
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| Q35717838 | HIF-dependent regulation of claudin-1 is central to intestinal epithelial tight junction integrity. |
| Q33581766 | HIF1A (rs11549465) and AKNA (rs10817595) Gene Polymorphisms Are Associated with Primary Sjögren's Syndrome |
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| Q57092220 | Hypoxia Exacerbates Inflammatory Acute Lung Injury the Toll-Like Receptor 4 Signaling Pathway |
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| Q41107802 | Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation. |
| Q52683574 | Hypoxia and acidosis: immune suppressors and therapeutic targets. |
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| Q34726144 | Hypoxia-Inducible Factor (HIF) as a Pharmacological Target for Prevention and Treatment of Infectious Diseases |
| Q38794703 | Hypoxia-Inducible Factor-1α and Autoimmune Lupus, Arthritis |
| Q39456881 | Hypoxia-Inducible Factors: Master Regulators of Cancer Progression |
| Q38907502 | Hypoxia-dependent regulation of inflammatory pathways in immune cells |
| Q85666783 | Hypoxia-inducible factor 1 in dendritic cells is crucial for the activation of protective regulatory T cells in murine colitis |
| Q39335943 | Hypoxia-inducible factor-1α: a promising therapeutic target for autoimmune diseases |
| Q26752304 | Hypoxia-inducible factors as molecular targets for liver diseases |
| Q93110790 | Hypoxia-inducible factors in CD4+ T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity |
| Q36237075 | Hypoxia-inducible factors in T lymphocyte differentiation and function. A Review in the Theme: Cellular Responses to Hypoxia |
| Q28081650 | Hypoxia-inducible factors regulate T cell metabolism and function |
| Q41678975 | Hypoxia-inducible factors: a central link between inflammation and cancer |
| Q28085029 | Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to Hypoxia |
| Q59793642 | Hypoxic Microenvironment and Metastatic Bone Disease |
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| Q47120916 | Hypoxic Stress-Induced Tumor and Immune Plasticity, Suppression, and Impact on Tumor Heterogeneity |
| Q46835597 | Hypoxic culture conditions enhance the generation of regulatory T cells |
| Q38848404 | Hypoxic stress: obstacles and opportunities for innovative immunotherapy of cancer |
| Q47774246 | Immune Regulation by Ubiquitin Tagging as Checkpoint Code. |
| Q58570450 | Immune regulation by protein ubiquitination: roles of the E3 ligases VHL and Itch |
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| Q46260887 | Intestinal hypoxia and hypoxia-induced signalling as therapeutic targets for IBD. |
| Q26749556 | Intrinsic and Tumor Microenvironment-Induced Metabolism Adaptations of T Cells and Impact on Their Differentiation and Function |
| Q47270990 | Knockdown of myeloid cell hypoxia-inducible factor-1α ameliorates the acute pathology in DSS-induced colitis |
| Q90220303 | Lactate dehydrogenase: a marker of diminished antitumor immunity |
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| Q96952138 | MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3+ regulatory T cells |
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| Q39265746 | Metabolic Cooperation and Competition in the Tumor Microenvironment: Implications for Therapy. |
| Q92072375 | Metabolic Pathways Involved in Regulatory T Cell Functionality |
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| Q92664771 | Metabolic influence on macrophage polarization and pathogenesis |
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| Q26798088 | Metabolic regulation of T cell differentiation and function |
| Q38403644 | Metabolic regulation of intestinal epithelial barrier during inflammation. |
| Q40065267 | Metabolism in Immune Cell Differentiation and Function. |
| Q97424076 | Metabolism of immune cells in cancer |
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| Q92511099 | Systemic silencing of PHD2 causes reversible immune regulatory dysfunction |
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