Hypoxic Stress-Induced Tumor and Immune Plasticity, Suppression, and Impact on Tumor Heterogeneity

scientific article published on 24 November 2017

Hypoxic Stress-Induced Tumor and Immune Plasticity, Suppression, and Impact on Tumor Heterogeneity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2017.01625
P932PMC publication ID5705542
P698PubMed publication ID29225600

P50authorSalem ChouaibQ98108267
P2093author name stringStéphane Terry
Stéphanie Buart
P2860cites workCutting edge: Hypoxia-induced Nanog favors the intratumoral infiltration of regulatory T cells and macrophages via direct regulation of TGF-β1.Q39063349
Hypoxia-inducible miR-210 regulates the susceptibility of tumor cells to lysis by cytotoxic T cellsQ39282438
Hypoxia induces escape from innate immunity in cancer cells via increased expression of ADAM10: role of nitric oxideQ39456593
Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.Q39496267
Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells.Q39507131
The cooperative induction of hypoxia-inducible factor-1 alpha and STAT3 during hypoxia induced an impairment of tumor susceptibility to CTL-mediated cell lysis.Q39876494
EMT in immuno-resistanceQ43141024
Plasticity of tumour and immune cells: a source of heterogeneity and a cause for therapy resistance?Q51239492
Acquisition of tumor cell phenotypic diversity along the EMT spectrum under hypoxic pressure: Consequences on susceptibility to cell-mediated cytotoxicity.Q53399279
Divergent effects of hypoxia on dendritic cell functionsQ56942671
Hypoxia-Inducible Factors and the Response to Hypoxic StressQ24629323
Targeting hypoxic response for cancer therapyQ26767351
Molecular pathways: hypoxia response in immune cells fighting or promoting cancerQ26829571
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Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to HypoxiaQ28085029
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeuticsQ29615944
Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxiaQ30554443
PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activationQ33569771
Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype.Q33588105
New insights into the role of EMT in tumor immune escape.Q33869781
HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironmentQ34243443
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA.Q34519307
Opposing roles for HIF-1α and HIF-2α in the regulation of angiogenesis by mononuclear phagocytesQ34568910
Hypoxia-inducible factors, stem cells, and cancerQ34625782
Targeting HIF1α eliminates cancer stem cells in hematological malignancies.Q34887224
E3 Ubiquitin Ligase VHL Regulates Hypoxia-Inducible Factor-1α to Maintain Regulatory T Cell Stability and Suppressive Capacity.Q35837701
CD47 blockade triggers T cell-mediated destruction of immunogenic tumorsQ36137576
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cellsQ36300305
Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosaQ36339991
The multifaceted role of autophagy in tumor evasion from immune surveillanceQ37109549
Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cellsQ37221453
ITPRs/inositol 1,4,5-trisphosphate receptors in autophagy: From enemy to allyQ38570193
Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma Induces an Immunosuppressive Tumor Microenvironment to Promote MetastasisQ38797313
EMT: 2016.Q38883448
Epithelial-to-mesenchymal transition (EMT) induced by inflammatory priming elicits mesenchymal stromal cell-like immune-modulatory properties in cancer cells.Q38911110
ITPR1 protects renal cancer cells against natural killer cells by inducing autophagyQ38949623
A mechanism of hypoxia-mediated escape from adaptive immunity in cancer cellsQ39043650
P921main subjecthypoxiaQ105688
P304page(s)1625
P577publication date2017-11-24
P1433published inFrontiers in ImmunologyQ27723748
P1476titleHypoxic Stress-Induced Tumor and Immune Plasticity, Suppression, and Impact on Tumor Heterogeneity
P478volume8

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cites work (P2860)
Q96155624Characterization of Hypoxia Signature to Evaluate the Tumor Immune Microenvironment and Predict Prognosis in Glioma Groups
Q58768316Chemokine Receptors and Exercise to Tackle the Inadequacy of T Cell Homing to the Tumor Site
Q61797406Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery
Q92874681Hepatic Tumor Microenvironments and Effects on NK Cell Phenotype and Function
Q59136348Hypoxia Modifies the Transcriptome of Human NK Cells, Modulates Their Immunoregulatory Profile, and Influences NK Cell Subset Migration
Q94503539Hypoxia increases mutational load of breast cancer cells through frameshift mutations
Q92637526MIF family proteins in genitourinary cancer: tumorigenic roles and therapeutic potential
Q64102265Rationale for Combining Radiotherapy and Immune Checkpoint Inhibition for Patients With Hypoxic Tumors
Q90697892Role and mechanism of programmed death-ligand 1 in hypoxia-induced liver cancer immune escape
Q57296955Role of Hypoxic Stress in Regulating Tumor Immunogenicity, Resistance and Plasticity
Q90293432The Air Sac Primordium of Drosophila: A Model for Invasive Development
Q107670795The regulation of immune checkpoints by the hypoxic tumor microenvironment

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