Hypoxia-inducible factor 1 in dendritic cells is crucial for the activation of protective regulatory T cells in murine colitis

scientific article published on 29 July 2015

Hypoxia-inducible factor 1 in dendritic cells is crucial for the activation of protective regulatory T cells in murine colitis is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1027535168
P356DOI10.1038/MI.2015.67
P698PubMed publication ID26220168

P50authorJoachim FandreyQ59550768
P2093author name stringG Breves
K Flück
S Winning
P2860cites workControl of T(H)17/T(reg) balance by hypoxia-inducible factor 1Q24336199
Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homingQ24646057
Hypoxia: an alarm signal during intestinal inflammationQ27691319
Control of regulatory T cell development by the transcription factor Foxp3Q27860489
Dendritic cells and the control of immunityQ27860918
Overview of retinoid metabolism and functionQ28026612
Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injuryQ28591880
Interleukin-10-deficient mice develop chronic enterocolitisQ29547881
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanismQ29614266
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acidQ29615586
HIF-1alpha is essential for myeloid cell-mediated inflammationQ29617581
Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protectionQ29618129
Retinoic acid imprints gut-homing specificity on T cellsQ29619126
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acidQ29619479
Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteriaQ29619620
Toll-like receptor 9-induced type I IFN protects mice from experimental colitisQ33683729
Anatomical basis of tolerance and immunity to intestinal antigensQ33965210
Fecal lipocalin 2, a sensitive and broadly dynamic non-invasive biomarker for intestinal inflammationQ34408108
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6Q34521302
Muc-2-deficient mice display a sex-specific, COX-2-related impairment of gastric mucosal repairQ34756209
The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cellsQ35167567
Mini-review: regulatory T cells and infection: suppression revisitedQ35651745
Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cellsQ35678887
Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosaQ36339991
Mucosal protection by hypoxia-inducible factor prolyl hydroxylase inhibition.Q36372667
Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activityQ36402484
Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammationQ36563545
Mucosal barrier in ulcerative colitis and Crohn's diseaseQ36877117
Regulation of hypoxia-inducible factors during inflammationQ36999102
Hypoxia and gastrointestinal diseaseQ37008518
Dendritic cells in intestinal immune regulation.Q37171796
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heartQ37256152
Role of mucosal dendritic cells in inflammatory bowel diseaseQ37263002
Monocytes and dendritic cells in a hypoxic environment: Spotlights on chemotaxis and migrationQ37300245
Toll-like receptor-7 ligand Imiquimod induces type I interferon and antimicrobial peptides to ameliorate dextran sodium sulfate-induced acute colitisQ37426746
Dendritic cells in intestinal homeostasis and disease.Q37591719
T cells, dendritic cells and epithelial cells in intestinal homeostasisQ37603610
Transmigrating neutrophils shape the mucosal microenvironment through localized oxygen depletion to influence resolution of inflammationQ37633213
Hypoxia and inflammationQ37842498
Role of hypoxia inducible factor-1α for interferon synthesis in mouse dendritic cellsQ38077750
Hydroxylases as therapeutic targets in inflammatory bowel disease.Q38082620
UVB induces HIF-1α-dependent TSLP expression via the JNK and ERK pathwaysQ39156879
Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis.Q40176806
Proinflammatory cytokines trigger MUC gene expression and mucin release in the intestinal cancer cell line LS180.Q40873306
Structural and functional analysis of hypoxia-inducible factor 1.Q41347443
Activation of HIF-1α does not increase intestinal tumorigenesis.Q41992484
Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier functionQ42989196
Characterization of the mouse Muc3 membrane bound intestinal mucin 5' coding and promoter regions: regulation by inflammatory cytokinesQ44485578
A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in miceQ44753508
Enhanced production of interleukin 6 in peripheral blood monocytes stimulated with mucins secreted into the bloodstreamQ46689390
Increased serum amyloid a levels reflect colitis severity and precede amyloid formation in IL-2 knockout miceQ46812863
The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis.Q46827571
Influence of hypoxia-inducible factor 1α on dendritic cell differentiation and migrationQ47844444
Hypoxia affects dendritic cell survival: role of the hypoxia-inducible factor-1α and lipopolysaccharide.Q53257878
Cysteine-rich domains of muc3 intestinal mucin promote cell migration, inhibit apoptosis, and accelerate wound healing.Q54452038
Bone Marrow-Derived Macrophages (BMM): Isolation and ApplicationsQ56882737
Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cellsQ61276176
Cutting Edge: Trans-Signaling via the Soluble IL-6R Abrogates the Induction of FoxP3 in Naive CD4+CD25- T CellsQ62658842
IL-6 is required for the development of Th1 cell-mediated murine colitisQ73709135
HIF-1 in T cells ameliorated dextran sodium sulfate-induced murine colitisQ83763046
P433issue2
P921main subjectdendritic cellQ506253
colitisQ2453464
P304page(s)379-390
P577publication date2015-07-29
P1433published inMucosal ImmunologyQ15817743
P1476titleHypoxia-inducible factor 1 in dendritic cells is crucial for the activation of protective regulatory T cells in murine colitis
P478volume9

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cites work (P2860)
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