Dendritic Cells under Hypoxia: How Oxygen Shortage Affects the Linkage between Innate and Adaptive Immunity

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Dendritic Cells under Hypoxia: How Oxygen Shortage Affects the Linkage between Innate and Adaptive Immunity is …
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scholarly articleQ13442814

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P356DOI10.1155/2016/5134329
P932PMC publication ID4757696
P698PubMed publication ID26966693
P5875ResearchGate publication ID293044910

P50authorJoachim FandreyQ59550768
P2093author name stringSandra Winning
P2860cites workHypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tensionQ24307473
Regulation of hypoxia-inducible factor-1alpha by NF-kappaBQ24657260
Dendritic cells and the control of immunityQ27860918
Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB siteQ28286400
Taking dendritic cells into medicineQ29619243
EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressorsQ33261811
Effects of TLR agonists on the hypoxia-regulated transcription factor HIF-1alpha and dendritic cell maturation under normoxic conditionsQ33601510
Succinate is an inflammatory signal that induces IL-1β through HIF-1α.Q33652731
Short-term hypoxia enhances the migratory capability of dendritic cell through HIF-1α and PI3K/Akt pathwayQ50663332
Inclusive estimation of complex antigen presentation functions of monocyte-derived dendritic cells differentiated under normoxia and hypoxia conditionsQ54348110
Chronic hypoxia reprograms human immature dendritic cells by inducing a proinflammatory phenotype and TREM-1 expressionQ60430710
Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivoQ60430715
Human dendritic cells differentiated in hypoxia down-modulate antigen uptake and change their chemokine expression profileQ60457330
Transcriptome of Hypoxic Immature Dendritic Cells: Modulation of Chemokine/Receptor ExpressionQ60457335
Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1α (HIF1A) and result in differential HIF1A-dependent gene expressionQ63407114
Hypoxia-inducible factor 1 in dendritic cells is crucial for the activation of protective regulatory T cells in murine colitisQ85666783
Dendritic cell regulation of TH1-TH2 developmentQ34023428
Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammationQ34028645
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulationQ34580976
Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expressionQ34770083
Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) contains hypoxia response elements: relevance to lytic induction by hypoxiaQ35019982
IRF-5-Mediated Inflammation Limits CD8+ T Cell Expansion by Inducing HIF-1α and Impairing Dendritic Cell Functions during Leishmania InfectionQ35653927
In vivo T Cell Activation in Lymphoid Tissues is Inhibited in the Oxygen-Poor MicroenvironmentQ35928036
IL-10: the master regulator of immunity to infectionQ37143028
NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alphaQ37158836
Monocytes and dendritic cells in a hypoxic environment: Spotlights on chemotaxis and migrationQ37300245
Interdependence of hypoxic and innate immune responsesQ37586121
HIF-α/MIF and NF-κB/IL-6 axes contribute to the recruitment of CD11b+Gr-1+ myeloid cells in hypoxic microenvironment of HNSCC.Q37689607
Decisions About Dendritic Cells: Past, Present, and FutureQ37963951
Role of hypoxia inducible factor-1α for interferon synthesis in mouse dendritic cellsQ38077750
Role of reactive oxygen species in the regulation of HIF-1 by prolyl hydroxylase 2 under mild hypoxiaQ39391401
Nitric oxide causes macrophage migration via the HIF-1-stimulated small GTPases Cdc42 and Rac1.Q39838660
Activation of the oxidative stress pathway by HIV-1 Vpr leads to induction of hypoxia-inducible factor 1alpha expressionQ39885717
EBV latent membrane protein 1 up-regulates hypoxia-inducible factor 1alpha through Siah1-mediated down-regulation of prolyl hydroxylases 1 and 3 in nasopharyngeal epithelial cellsQ40219046
Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-kappaB.Q40305741
HIF-1 expression in healing wounds: HIF-1α induction in primary inflammatory cells by TNF-αQ40769970
HIF-1α influences myeloid cell antigen presentation and response to subcutaneous OVA vaccinationQ42051899
Cutting edge: Lipopolysaccharide induces IL-10-producing regulatory CD4+ T cells that suppress the CD8+ T cell responseQ42631213
HIF-dependent induction of adenosine receptor A2b skews human dendritic cells to a Th2-stimulating phenotype under hypoxiaQ43258538
The hypoxic environment reprograms the cytokine/chemokine expression profile of human mature dendritic cellsQ44269341
HIF-1α is a negative regulator of plasmacytoid DC development in vitro and in vivoQ44275769
Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathwayQ44509761
Hypoxia and hypoxia-inducible factor-1 alpha modulate lipopolysaccharide-induced dendritic cell activation and functionQ44869825
Hypoxia stimulus: An adaptive immune response during dendritic cell maturation.Q46793630
Dendritic cell reprogramming by the hypoxic environmentQ47249620
Influence of hypoxia-inducible factor 1α on dendritic cell differentiation and migrationQ47844444
Silver nanoparticle-induced hMSC proliferation is associated with HIF-1α-mediated upregulation of IL-8 expressionQ48672914
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectoxygenQ629
cellQ7868
hypoxiaQ105688
dendritic cellQ506253
inorganic compoundQ190065
adaptive immune systemQ1645075
hemic and immune systemsQ70202933
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)5134329
P577publication date2016-02-04
P13046publication type of scholarly workreview articleQ7318358
P1433published inJournal of Immunology ResearchQ26841936
P1476titleDendritic Cells under Hypoxia: How Oxygen Shortage Affects the Linkage between Innate and Adaptive Immunity
P478volume2016

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cites work (P2860)
Q30241888Dendritic cells and adipose tissue
Q90601927Differential expression of immune markers in the patients with obstructive sleep apnea/hypopnea syndrome
Q56523156HIV vaccine candidate activation of hypoxia and the inflammasome in CD14 monocytes is associated with a decreased risk of SIV acquisition
Q38998450Hypoxia and antitumor CD8+ T cells: An incompatible alliance?
Q37690509Immunogenicity is preferentially induced in sparse dendritic cell cultures.

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