| scholarly article | Q13442814 |
| P50 | author | Timothy Alan Bielecki | Q85318335 |
| Hamid Band | Q88305372 | ||
| Bhopal C Mohapatra | Q57039662 | ||
| P2093 | author name string | Vimla Band | |
| Wei An | |||
| Seishi Ogawa | |||
| Masashi Sanada | |||
| Haitao Luan | |||
| Matthew D Storck | |||
| Gulzar Ahmad | |||
| Insha Mushtaq | |||
| Neha Zutshi | |||
| Scott A Nadeau | |||
| P2860 | cites work | Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b | Q59058408 |
| Mechanism of down-regulation of c-kit receptor. Roles of receptor tyrosine kinase, phosphatidylinositol 3'-kinase, and protein kinase C | Q71661337 | ||
| The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor | Q73316781 | ||
| The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor | Q78069495 | ||
| Cbl exposes its RING finger | Q83388672 | ||
| Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G | Q24309656 | ||
| Identification and functional characterization of an Src homology domain 3 domain-binding site on Cbl | Q24313251 | ||
| v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas | Q24624849 | ||
| Phosphotyrosine Binding Domain-Dependent Upregulation of the Platelet-Derived Growth Factor Receptor α Signaling Cascade by Transforming Mutants of Cbl: Implications for Cbl’s Function and Oncogenicity | Q24645473 | ||
| Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases | Q26852269 | ||
| Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors | Q28207179 | ||
| Negative regulation of Lck by Cbl ubiquitin ligase | Q28208259 | ||
| Proto-oncoprotein Vav interacts with c-Cbl in activated thymocytes and peripheral T cells | Q28242076 | ||
| The protein product of the c-cbl protooncogene is the 120-kDa tyrosine-phosphorylated protein in Jurkat cells activated via the T cell antigen receptor | Q28247924 | ||
| A Role for CAP, a Novel, Multifunctional Src Homology 3 Domain-containing Protein in Formation of Actin Stress Fibers and Focal Adhesions | Q28261445 | ||
| The Cbl interactome and its functions | Q28277251 | ||
| Sequences Surrounding the Src-Homology 3 Domain of Phospholipase Cγ-1 Increase the Domain's Association with Cbl | Q28280205 | ||
| A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells | Q28289338 | ||
| Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323 | Q28291812 | ||
| The non-receptor tyrosine kinase Syk is a target of Cbl-mediated ubiquitylation upon B-cell receptor stimulation. | Q28366332 | ||
| p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase | Q28610005 | ||
| Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia | Q29615735 | ||
| The Cbl proto-oncogene product negatively regulates the Src-family tyrosine kinase Fyn by enhancing its degradation | Q30175273 | ||
| The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase | Q30193184 | ||
| Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cells | Q30193317 | ||
| Crk interacts with tyrosine-phosphorylated p116 upon T cell activation | Q30193645 | ||
| Physical association between Src homology 3 elements and the protein product of the c-cbl proto-oncogene | Q30194245 | ||
| Rapid T-cell receptor-mediated tyrosine phosphorylation of p120, an Fyn/Lck Src homology 3 domain-binding protein | Q30194346 | ||
| RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation | Q32138771 | ||
| Altered thymic positive selection and intracellular signals in Cbl-deficient mice | Q33596728 | ||
| Mutations of an E3 ubiquitin ligase c-Cbl but not TET2 mutations are pathogenic in juvenile myelomonocytic leukemia | Q33722741 | ||
| Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice | Q33776192 | ||
| Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells. | Q34088521 | ||
| Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia | Q34130332 | ||
| Rapidly fatal myeloproliferative disorders in mice with deletion of Casitas B-cell lymphoma (Cbl) and Cbl-b in hematopoietic stem cells | Q34136434 | ||
| c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation | Q34157660 | ||
| Novel oncogenic mutations of CBL in human acute myeloid leukemia that activate growth and survival pathways depend on increased metabolism | Q34186690 | ||
| Cbl: many adaptations to regulate protein tyrosine kinases | Q34205572 | ||
| WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation | Q34220865 | ||
| The Loss of Cbl-Phosphatidylinositol 3-Kinase Interaction Perturbs RANKL-mediated Signaling, Inhibiting Bone Resorption and Promoting Osteoclast Survival | Q34299184 | ||
| Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations | Q34317446 | ||
| Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration. | Q34452683 | ||
| Src promotes destruction of c-Cbl: implications for oncogenic synergy between Src and growth factor receptors | Q34806104 | ||
| Dasatinib targets B-lineage cells but does not provide an effective therapy for myeloproliferative disease in c-Cbl RING finger mutant mice | Q35144330 | ||
| Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia | Q35901705 | ||
| Cbl-3-deficient mice exhibit normal epithelial development | Q36138338 | ||
| The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha | Q36164471 | ||
| Physical and functional association of the cbl protooncogen product with an src-family protein tyrosine kinase, p53/56lyn, in the B cell antigen receptor-mediated signaling | Q36366183 | ||
| The E3 ubiquitin ligase c-Cbl restricts development and functions of hematopoietic stem cells | Q36585519 | ||
| Mutations in CBL occur frequently in juvenile myelomonocytic leukemia | Q37334614 | ||
| Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene | Q37636620 | ||
| Mutations of the TET2 and CBL genes: novel molecular markers in myeloid malignancies | Q37701292 | ||
| Repression of c-Cbl leads to enhanced G-CSF Jak-STAT signaling without increased cell proliferation | Q38363901 | ||
| Juvenile myelomonocytic leukaemia-associated mutation in Cbl promotes resistance to apoptosis via the Lyn-PI3K/AKT pathway | Q39029990 | ||
| CBL Linker Region and RING Finger Mutations Lead to Enhanced Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) Signaling via Elevated Levels of JAK2 and LYN | Q39148813 | ||
| Inhibition of SRC Corrects GM-CSF Hypersensitivity That Underlies Juvenile Myelomonocytic Leukemia | Q39196331 | ||
| CBL mutations in myeloproliferative neoplasms are also found in the gene's proline-rich domain and in patients with the V617FJAK2. | Q39399799 | ||
| Binding of Cbl to a phospholipase Cgamma1-docking site on platelet-derived growth factor receptor beta provides a dual mechanism of negative regulation | Q40109529 | ||
| Direct binding of Cbl to Tyr568 and Tyr936 of the stem cell factor receptor/c-Kit is required for ligand-induced ubiquitination, internalization and degradation. | Q40266580 | ||
| Regulation of stem cell factor receptor signaling by Cbl family proteins (Cbl-b/c-Cbl). | Q40524623 | ||
| Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b | Q40531841 | ||
| Biochemical basis for the requirement of kinase activity for Cbl-dependent ubiquitinylation and degradation of a target tyrosine kinase | Q40543230 | ||
| Cbl promotes ubiquitination of the T cell receptor zeta through an adaptor function of Zap-70. | Q40806098 | ||
| The linker phosphorylation site Tyr292 mediates the negative regulatory effect of Cbl on ZAP-70 in T cells | Q40884199 | ||
| Cbl-b regulates the CD28 dependence of T-cell activation. | Q40904107 | ||
| Leucine zipper-mediated homodimerization of the adaptor protein c-Cbl. A role in c-Cbl's tyrosine phosphorylation and its association with epidermal growth factor receptor | Q40923031 | ||
| Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy. | Q41076612 | ||
| Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins | Q42160561 | ||
| Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms | Q42795736 | ||
| 250K single nucleotide polymorphism array karyotyping identifies acquired uniparental disomy and homozygous mutations, including novel missense substitutions of c-Cbl, in myeloid malignancies | Q43078973 | ||
| Cbl-mediated ubiquitinylation and negative regulation of Vav. | Q43578123 | ||
| Molecular complexes that contain both c-Cbl and c-Src associate with Golgi membranes | Q43917038 | ||
| Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms | Q47960630 | ||
| CBL mutation-related patterns of phosphorylation and sensitivity to tyrosine kinase inhibitors | Q54329349 | ||
| Myeloid Leukemia Development in c-Cbl RING Finger Mutant Mice Is Dependent on FLT3 Signaling | Q54642331 | ||
| Flt3-dependent transformation by inactivating c-Cbl mutations in AML | Q57269958 | ||
| The RING Finger Domain of Cbl Is Essential for Negative Regulation of the Syk Tyrosine Kinase | Q58179986 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 3666-3682 | |
| P577 | publication date | 2017-01-12 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Structural Determinants of the Gain-of-Function Phenotype of Human Leukemia-associated Mutant CBL Oncogene | |
| P478 | volume | 292 |
| Q90371256 | c-Cbl Expression Correlates with Human Colorectal Cancer Survival and Its Wnt/β-Catenin Suppressor Function Is Regulated by Tyr371 Phosphorylation | cites work | P2860 |
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