| Q53562298 | 'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR. |
| Q41734593 | A binding site for the T-cell co-receptor CD8 on the alpha 3 domain of HLA-A2. |
| Q40801692 | A challenge to the instructive model of positive selection |
| Q46608878 | A combination of a particular HLA-DP beta allele and an HLA-DQ heterodimer confers susceptibility to coeliac disease |
| Q36230129 | A gamma/delta cell receptor heterodimer induces the expression of CD4 and CD8 in thymocytes |
| Q71889571 | A gut-homing, oligoclonal CD4+ T cell population in severe-combined immunodeficient mice expressing a rearranged, transgenic class I-restricted alpha beta T cell receptor |
| Q51132081 | A human CD4 transgene rescues CD4-CD8+ cells in beta 2-microglobulin-deficient mice. |
| Q52930208 | A kinetic window constricts the T cell receptor repertoire in the thymus. |
| Q41701573 | A novel MHC class I-related molecule expressed on mouse thymic stroma cells and mature lymphocytes |
| Q81291549 | A novel role for CD28 in thymic selection: elimination of CD28/B7 interactions increases positive selection |
| Q73690847 | A novel, highly efficient peptide-HLA class I binding assay using unfolded heavy chain molecules: identification of HIV-1 derived peptides that bind to HLA-A*0201 and HLA-A*0301 |
| Q42058596 | A potential role for Elf-1 in CD4 promoter function |
| Q36807094 | A recombinant antibody with the antigen-specific, major histocompatibility complex-restricted specificity of T cells. |
| Q24601796 | A specific HLA-DP beta allele is associated with pauciarticular juvenile rheumatoid arthritis but not adult rheumatoid arthritis |
| Q40792734 | A transcriptional silencer controls the developmental expression of the CD4 gene. |
| Q68046975 | A unified model for T cell antigen recognition and thymic selection of the T cell repertoire |
| Q52075352 | A viral peptide can mimic an endogenous peptide for allorecognition of a major histocompatibility complex class I product |
| Q58991614 | Accessories or coreceptors? |
| Q70567962 | Activation of extrathymic T cells in the liver during liver regeneration following partial hepatectomy |
| Q67697654 | Activation of human thymocytes by antibodies to the CD3/T-cell receptor complex: Triggering of different epitopes results in different signals |
| Q36002606 | Activation of naturally occurring lung CD4(+)CD25(+) regulatory T cells requires CD8 and MHC I interaction |
| Q52165633 | Affinity of thymic self-peptides for the TCR determines the selection of CD8(+) T lymphocytes in the thymus. |
| Q45889625 | All or none peripheral tolerance induction in H-Y antigen-specific TCR transgenic mice |
| Q58143695 | Allelic sequence variation in the HLA class II genes and proteins in patients with autoimmune hepatitis |
| Q33867426 | Allorecognition of DR1 by T cells from a DR4/DRw13 responder mimics self-restricted recognition of endogenous peptides |
| Q41099544 | Altered major histocompatibility complex-restricted antigen recognition by T cells from elderly humans |
| Q58690522 | An Emerging Role for Serine Protease Inhibitors in T Lymphocyte Immunity and Beyond |
| Q36401412 | An opposite pattern of selection of a single T cell antigen receptor in the thymus and among intraepithelial lymphocytes |
| Q36230612 | An unusual lineage of alpha/beta T cells that contains autoreactive cells |
| Q42941471 | Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex |
| Q37373793 | Analysis of the immune system with transgenic mice: T cell development |
| Q51573067 | Analysis of the inflammatory response in HY-TCR transgenic mice highlights the pathogenic potential of CD4- CD8- T cells. |
| Q41658115 | Analysis of the peripheral T-cell compartment in the MHC class II deficiency syndrome |
| Q36364608 | Anergy and exhaustion are independent mechanisms of peripheral T cell tolerance |
| Q56888991 | Antibodies against the T cell receptor/CD3 complex interfere with distinct intra-thymic cell-cell interactionsin vivo: correlation with arrest of T cell differentiation |
| Q40833872 | Antigen receptors on T and B lymphocytes: parallels in organization and function |
| Q37620959 | Antigen-receptor induced clonal expansion and deletion of lymphocytes are impaired in mice lacking HS1 protein, a substrate of the antigen-receptor-coupled tyrosine kinases |
| Q35656611 | Apoptosis and T-cell repertoire selection in the thymus |
| Q35370169 | Apoptosis in the development of the immune system: growth factors, clonal selection and bcl-2 |
| Q40615110 | Are MHC-bound peptides a nuisance for positive selection? |
| Q59127586 | Association of bovine major histocompatibility complex (BoLA) gene polymorphism with colostrum and milk microbiota of dairy cows during the first week of lactation |
| Q71066513 | Asymmetric redundancy in CD4 silencer function |
| Q41710718 | Autoimmunity, immunologic tolerance, and gene therapy |
| Q36369138 | Autonomous maturation of alpha/beta T lineage cells in the absence of COOH-terminal Src kinase (Csk). |
| Q54323329 | Autoreactive T cells in normal mice: unrestricted recognition of self peptides on dendritic cell I-A molecules by CD4-CD8- T cell receptor alpha/beta+ T cell clones expressing V beta 8.1 gene segments. |
| Q38760990 | B and T cell antigen receptor repertoires in lupus/arthritis murine models |
| Q35869104 | Bcl-2 expression during T-cell development: early loss and late return occur at specific stages of commitment to differentiation and survival |
| Q52862373 | Biased expression of individual T cell receptor V gene segments in CD4+ and CD8+ human peripheral blood T lymphocytes |
| Q67902646 | Bone marrow-derived progenitor T cells convey the origin of maturational arrest from CD4+CD8+ to CD4−CD8+ thymocytes in LEC mutant rats |
| Q36371828 | CD27 Promotes Survival of Activated T Cells and Complements CD28 in Generation and Establishment of the Effector T Cell Pool |
| Q36370455 | CD28 costimulation is required for in vivo induction of peripheral tolerance in CD8 T cells |
| Q71118162 | CD3-induced apoptosis of CD4+CD8+ thymocytes in the absence of clonotypic T cell antigen receptor |
| Q68089269 | CD4+CD8+ thymocytes are susceptible to DNA fragmentation induced by phorbol ester, calcium ionophore and anti-CD3 antibody |
| Q54286224 | CD4+CD8+CD3high thymocytes appear transiently during ontogeny: evidence from phenotypic and functional studies |
| Q36071442 | CD4-CD8 lineage differentiation: Thpok-ing into the nucleus |
| Q68056870 | CD4-CD8+ T-cell receptor-alpha beta+ major histocompatibility complex class-II-specific T-cell clones isolated from aged athymic mice |
| Q35769448 | CD4/CD8 coreceptors in thymocyte development, selection, and lineage commitment: analysis of the CD4/CD8 lineage decision |
| Q40994026 | CD4/CD8 lineage commitment: back to instruction? |
| Q35824059 | CD4/CD8-lineage differentiation in the thymus: from nuclear effectors to membrane signals |
| Q73468032 | CD45 enhances positive selection and is expressed at a high level in large, cycling, positively selected CD4+CD8+ thymocytes |
| Q54247021 | CD69 expression during selection and maturation of CD4+8+ thymocytes. |
| Q33963637 | CD8 coreceptor extinction in signaled CD4(+)CD8(+) thymocytes: coordinate roles for both transcriptional and posttranscriptional regulatory mechanisms in developing thymocytes |
| Q70527012 | CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny |
| Q36350462 | CD8 is required during positive selection of CD4-/CD8+ T cells |
| Q36231201 | CD8 surface levels alter the fate of alpha/beta T cell receptor-expressing thymocytes in transgenic mice |
| Q40729394 | CD8+ T cell tolerance and autoimmunity to extra-thymic antigens |
| Q48065352 | CTX, a novel molecule specifically expressed on the surface of cortical thymocytes in Xenopus. |
| Q36222775 | Cell-specific regulation of apoptosis by designed enediynes |
| Q71785375 | Cellular competition modulates survival and selection of CD8+ T cells |
| Q52218448 | Central tolerance: clonal deletion or clonal arrest? |
| Q40434747 | Changes in the Intestinal Lymphoid Compartment Throughout Life: Implications for the Local Generation of Intestinal T Cells |
| Q42151891 | Chicken major histocompatibility complex congenic lines differ in the percentages of lymphocytes bearing CD4 and CD8 antigens |
| Q36361696 | Clonal anergy blocks in vivo growth of mature T cells and can be reversed in the absence of antigen |
| Q41817218 | Coming to grips with Notch |
| Q36380314 | Commitment of immature CD4+8+ thymocytes to the CD4 lineage requires CD3 signaling but does not require expression of clonotypic T cell receptor (TCR) chains |
| Q36701545 | Constitutive Tyrosine Phosphorylation of the T-Cell Receptor (TCR) ζ Subunit: Regulation of TCR-Associated Protein Tyrosine Kinase Activity by TCR ζ |
| Q40374666 | Control of T-cell development by the pre-T and alpha beta T-cell receptor |
| Q36409478 | Control of gamma delta T-cell development. |
| Q41646846 | Coordinate change in phenotype in a mouse cell line selected for CD8 expression |
| Q68422653 | Correlation between the V beta 4+ CD8+ T-cell population and the H-2d haplotype |
| Q36365822 | Critical role for the common cytokine receptor gamma chain in intrathymic and peripheral T cell selection |
| Q47740949 | Crucial function of the pre-T-cell receptor (TCR) in TCR beta selection, TCR beta allelic exclusion and alpha beta versus gamma delta lineage commitment |
| Q36089503 | Current status review: antibodies to the T cell antigen receptor |
| Q69739647 | Cytotoxic T lymphocyte recognition of HLA-A2 antigens in normal and HLA-Cw3-transgenic mice |
| Q71764422 | Cytotoxic activity against tumour cells mediated by intermediate TCR cells in the liver and spleen |
| Q33558790 | DR3 regulates negative selection during thymocyte development |
| Q30443591 | Death pathways in T cell homeostasis and their role in autoimmune diabetes |
| Q34305240 | Deciphering thymic development |
| Q36402681 | Defined alphabeta T cell receptors with distinct ligand specificities do not require those ligands to signal double negative thymocyte differentiation |
| Q36367518 | Delayed maturation of CD4- CD8- Fc gamma RII/III+ T and natural killer cell precursors in Fc epsilon RI gamma transgenic mice |
| Q36356209 | Deletion of autospecific T cells in T cell receptor (TCR) transgenic mice spares cells with normal TCR levels and low levels of CD8 molecules |
| Q51061315 | Deletion of the CD4 silencer element supports a stochastic mechanism of thymocyte lineage commitment. |
| Q42186905 | Demonstration of Functional Heterogeneity of T lymphocytes and Identification of Their Two Major Subsets |
| Q36357132 | Depletion of CD8+ cells in human thymic medulla results in selective immune deficiency |
| Q33938706 | Development and function of T cells in mice with a disrupted CD2 gene |
| Q72650435 | Development of T cells in SCID mice grafted with fetal thymus from AKR mice or F344 rats |
| Q35923678 | Development of the CD4 and CD8 lineage of T cells: instruction versus selection |
| Q52208053 | Developmental changes predispose the fetal thymus to positive selection of CD4+CD8- T cells |
| Q41855601 | Developmental regulation of thymocyte susceptibility to deletion by "self"-peptide |
| Q41570922 | Differential effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin, bis(tri-n-butyltin) oxide and cyclosporine on thymus histophysiology |
| Q36363091 | Differential effects of zeta and eta transgenes on early alpha/beta T cell development |
| Q37161842 | Differential role of the transcription factor NF-kappaB in selection and survival of CD4+ and CD8+ thymocytes |
| Q44556255 | Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes. |
| Q36228639 | Differential synergy of Notch and T cell receptor signaling determines alphabeta versus gammadelta lineage fate. |
| Q71150829 | Differential usage of T-cell receptor V beta gene families by CD4+ and CD8+ T cells in patients with CD8hi common variable immunodeficiency: evidence of a post-thymic effect |
| Q68074355 | Disruption of CD8-dependent negative and positive selection of thymocytes is correlated with a decreased association between CD8 and the protein tyrosine kinase, p56lck |
| Q44704873 | Distinct sequence of negative or positive selection implied by thymocyte T-cell receptor densities |
| Q37583565 | Dominant expression of a distinctive V14+ T-cell antigen receptor alpha chain in mice |
| Q67905145 | Double-Negative (CD4-CD8-), TCRalphabeta-Expressing, Peripheral T Cells |
| Q36364748 | Dual T cell receptor beta chain expression on human T lymphocytes |
| Q61419908 | Early degenerate selection of thymocytes by class I major histocompatibility complex |
| Q36363101 | Early progression of thymocytes along the CD4/CD8 developmental pathway is regulated by a subset of thymic epithelial cells expressing transforming growth factor beta |
| Q43690329 | Effect of phorbol ester and calcium ionophore on human thymocytes |
| Q33609038 | Elimination of CD8+ thymocytes in transgenic mice expressing an anti-Lyt2.2 immunoglobulin heavy chain gene |
| Q38002514 | Elucidating the pathogenesis of autoimmune disease: recent advances at the molecular level and relevance to oral mucosal disease |
| Q36356927 | Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways |
| Q35605098 | Engagement of the external domains of CD45 tyrosine phosphatase can regulate the differentiation of immature CD4+CD8+ thymocytes into mature T cells |
| Q36231030 | Estrogen administration activates extrathymic T cell differentiation in the liver |
| Q45155438 | Evidence for a differential avidity model of T cell selection in the thymus |
| Q36362755 | Evidence for differential intracellular signaling via CD4 and CD8 molecules |
| Q38329183 | Exclusion and inclusion of α and β T cell receptor alleles |
| Q67532966 | Existence of mature human CD4+ T cells with genuine class I restriction |
| Q72463019 | Expansion of intermediate T-cell receptor cells in mice with autoimmune-like graft-versus-host disease |
| Q68436451 | Expression of the human V beta 8 gene product preferentially correlates with class II major histocompatibility complex restriction specificity |
| Q40686863 | Extrathymic pathways of T-cell differentiation in the liver and other organs |
| Q71645614 | FK506 inhibits the differentiation of developing thymocytes but not negative selection of T cell receptor Vβ5+ and Vβ;11+ T lymphocytes in vivo |
| Q34507508 | Facilitation of beta selection and modification of positive selection in the thymus of PD-1-deficient mice |
| Q57078475 | Failure of HY-Specific Thymocytes to Escape Negative Selection by Receptor Editing |
| Q52291012 | Feedback regulation of T cell development: manifestations in aging. |
| Q36362299 | Functional GATA-3 binding sites within murine CD8 alpha upstream regulatory sequences |
| Q34028508 | Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells |
| Q51137998 | Generation of mature T cell populations in the thymus: CD4 or CD8 down-regulation occurs at different stages of thymocyte differentiation. |
| Q35532733 | Genetic analysis of susceptibility to type 1 diabetes |
| Q36537692 | Genetic control of immune response and disease susceptibility by the HLA-DQ gene |
| Q41610117 | HLA class II peptide binding specificity and autoimmunity |
| Q42024302 | Highly restricted T cell repertoire shaped by a single major histocompatibility complex-peptide ligand in the presence of a single rearranged T cell receptor beta chain |
| Q92653789 | How does the immune system learn to distinguish between good and evil? The first definitive studies of T cell central tolerance and positive selection |
| Q37977320 | How the TCR balances sensitivity and specificity for the recognition of self and pathogens. |
| Q36365522 | Human CD8 transgene regulation of HLA recognition by murine T cells |
| Q47637082 | Identification of lineage-specifying cytokines that signal all CD8+-cytotoxic-lineage-fate 'decisions' in the thymus. |
| Q38606072 | Idiotypic regulation of T cells in graft-versus-host disease and autoimmunity |
| Q36562973 | Immune Cell Identity: Perspective from a Palimpsest |
| Q73339904 | Immunity or tolerance: opposite outcomes of microchimerism from skin grafts |
| Q68083776 | Immunohistology of T cell differentiation in the thymus of H-Y-specific T cell receptor alpha/beta transgenic mice |
| Q57185434 | Impaired Negative Selection of T Cells in Hodgkin's Disease Antigen CD30–Deficient Mice |
| Q28589968 | Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice |
| Q79074350 | In Vivo Treatment of Class II MHC-Deficient Mice with Anti-TCR Antibody Restores the Generation of Circulating CD4 T Cells and Optimal Architecture of Thymic Medulla |
| Q36231231 | In vivo and in vitro clonal deletion of double-positive thymocytes |
| Q36527898 | Induction of Immunological Unresponsiveness in vivo and in vitro by Conventional and Super-Antigens in Developing and Mature T Cells |
| Q73013446 | Induction of the specific tolerance and enhancing the allograft survival by transfection of recipient cells with donor MHC class I cDNA |
| Q73899965 | Influence of estrogen deficiency and replacement on T-cell populations in rat lymphoid tissues and organs |
| Q64448633 | Insights into T-Cell Development from Studies Using Transgenic and Knockout Mice |
| Q36096780 | Interactions with multiple peptide ligands determine the fate of developing thymocytes. |
| Q71918566 | Intra- and extra-thymic expression of the pre-T cell receptor alpha gene |
| Q67568266 | Intrathymic injection of donor alloantigens induces donor-specific vascularized allograft tolerance without immunosuppression |
| Q37693679 | Involvement of p21ras distinguishes positive and negative selection in thymocytes |
| Q37113952 | Kinetics of Negative and Positive Selection in the Thymus |
| Q37730111 | Kinetics of mature T-cell development in the thymus |
| Q30159670 | Lck SH3 domain function is required for T-cell receptor signals regulating thymocyte development |
| Q34831201 | Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice |
| Q59792917 | Live-Cell FRET Imaging Reveals a Role of Extracellular Signal-Regulated Kinase Activity Dynamics in Thymocyte Motility |
| Q67924867 | Lymphotoxin activates hepatic T cells and simultaneously induces profound thymic atrophy |
| Q70706485 | MHC class II presenting cells are necessary for the induction of intrathymic tolerance |
| Q37464963 | MHC restriction and allogeneic immune responses. |
| Q38665386 | MHC-antigen interaction: what does the T cell receptor see? |
| Q35197104 | Major Histocompatibility Complex class IIb polymorphism influences gut microbiota composition and diversity |
| Q36354135 | Maturational arrest from CD4+8+ to CD4+8- thymocytes in a mutant strain (LEC) of rat. |
| Q24538980 | Medical immunology: a new journal for a new subspecialty |
| Q36352076 | Molecular analysis of the influences of positive selection, tolerance induction, and antigen presentation on the T cell receptor repertoire |
| Q38220900 | Molecular and cellular events of T cell development |
| Q34981899 | Molecular and cellular mechanisms of donor cell-induced tolerance |
| Q36681942 | Mutagenesis and Expression of Putative Class II Susceptibility Genes: a “Reverse Immunogenetics” Approach to Analysis of HLA and Disease |
| Q38680365 | Mutational analysis of the structure and function of the CD4 protein |
| Q36230282 | Mutations in CD8 that affect interactions with HLA class I and monoclonal anti-CD8 antibodies |
| Q58451234 | Mutations in the major histocompatibility complex class I antigen-presenting groove affect both negative and positive selection of T cells |
| Q37995690 | NF-κB subunit specificity in hemopoiesis. |
| Q52057518 | Naive T cells can mediate delayed-type hypersensitivity response in T cell receptor transgenic mice. |
| Q44276459 | Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the alpha 3 domain of MHC I molecules |
| Q39458972 | Negative regulation of CD4 gene expression by a HES-1-c-Myb complex |
| Q59058408 | Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b |
| Q34547220 | New perspectives on a developmental dilemma: the kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision |
| Q37111712 | Non-deletional mechanisms of peripheral and central tolerance: studies with transgenic mice with tissue-specific expression of a foreign MHC class I antigen |
| Q86190175 | Normal development and function but impaired memory phenotype of CD8⁺ T cells in transgenic mice expressing HIV-1 Nef in its natural target cells |
| Q68317625 | Ontogeny of T cell maturation in LEC mutant rats which bear a congenital arrest of maturation from CD4+CD8+ to CD4+CD8− thymocytes |
| Q39912767 | Organ-specific autoimmunity in mice whose T cell repertoire is shaped by a single antigenic peptide |
| Q59096940 | Participation of CD4 coreceptor molecules in T-cell repertoire selection |
| Q36364795 | Peptide binding specificity of HLA-DR4 molecules: correlation with rheumatoid arthritis association |
| Q63363368 | Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymus |
| Q51103760 | Peptide-induced positive selection of TCR transgenic thymocytes in a coreceptor-independent manner. |
| Q69208568 | Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo |
| Q36380653 | Peripheral selection of T cell repertoires: the role of continuous thymus output |
| Q48040399 | Pertussis toxin can replace T cell receptor signals that induce positive selection of CD8 T cells |
| Q51148862 | Phenotypic changes accompanying positive selection of CD4+CD8+ thymocytes |
| Q36482546 | Phospholipase Cγ2 plays a role in TCR signal transduction and T cell selection |
| Q62590795 | Positive and Negative CD4+ Thymocyte Selection by a Single MHC Class II/Peptide Ligand Affected by Its Expression Level in the Thymus |
| Q81306346 | Positive and negative selection in Basel |
| Q36367050 | Positive and negative selection invoke distinct signaling pathways. |
| Q35556452 | Positive and negative selection of T cell repertoires during differentiation in allogeneic bone marrow chimeras |
| Q35045775 | Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene |
| Q35879598 | Positive and negative selection of the T cell repertoire: role of MHC and other ligands |
| Q51090801 | Positive selection as a developmental progression initiated by alpha beta TCR signals that fix TCR specificity prior to lineage commitment. |
| Q36356589 | Positive selection determines T cell receptor V beta 14 gene usage by CD8+ T cells |
| Q52214778 | Positive selection of CD4+ T cells by TCR ligation without aggregation even in the absence of MHC. |
| Q58993577 | Positive selection of CD4-CD8+ T cells in the thymus of normal mice |
| Q36365004 | Positive selection of T cells: rescue from programmed cell death and differentiation require continual engagement of the T cell receptor. |
| Q34287303 | Positive selection of a T-cell subpopulation in the thymus in which it develops |
| Q59080081 | Positive selection of antigen-specific T cells in thymus by restricting MHC molecules |
| Q37852643 | Positive selection of gamma delta T cells |
| Q40801741 | Positive selection of immature alpha beta T cells |
| Q51085683 | Positive selection of thymocytes induced by gene transfer: MHC class II-mediated selection of CD8 lineage cells. |
| Q33740209 | Positive selection of thymocytes: the long and winding road. |
| Q33741290 | Positive selection of transgenic receptor-bearing thymocytes by Kb antigen is altered by Kb mutations that involve peptide binding |
| Q68158055 | Postnatal development of T lymphocytes in a novel X-linked immunodeficiency disease |
| Q42000372 | Preferential association of α and β chains of the T cell antigen receptor |
| Q36356355 | Preferential differentiation of T cell receptor specificities based on the MHC glycoproteins encountered during development. Evidence for positive selection |
| Q68302432 | Preferential expression of Vβ6.7 domain on human peripheral CD4+ T cells. Implication for positive selection of T cells in man |
| Q41325052 | Presentation of antigen, foreign major histocompatibility complex proteins and self by thymus cortical epithelium |
| Q46409946 | Prethymic Nylon Wool-Passed Bone Marrow Cells, Substituting for Helper T Cells, Can Augment the Generation of Cytotoxic T Lymphocytes from Their Precursors |
| Q59081175 | Prevention of diabetes in non-obese diabetic I-Ak transgenic mice |
| Q48612168 | Proceedings of the conference "Lymphocyte development, tolerance and autoimmunity: solved and open questions", held at the Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, on May 12, 2011 (Wrocław, Polan |
| Q39120700 | Programmed cell death and the immune system |
| Q71740162 | Raf regulates positive selection |
| Q44278812 | Rat Thymic Epithelium Positively Selects Mouse T Cells with Specificity for Rat MHC Class II Antigens but Fails to Induce Detectable Tolerance in the Mouse T Cells to the Rat MHC Antigens |
| Q37428024 | Receptor-stimulated death pathway is opened by antigen in mature T cells |
| Q37718898 | Recognition by CD8 on cytotoxic T lymphocytes is ablated by several substitutions in the class I alpha 3 domain: CD8 and the T-cell receptor recognize the same class I molecule |
| Q37624987 | Recognition of beta 2-microglobulin-negative (beta 2m-) T-cell blasts by natural killer cells from normal but not from beta 2m- mice: nonresponsiveness controlled by beta 2m- bone marrow in chimeric mice |
| Q24680530 | Reconstitution of the subclass-specific expression of CD4 in thymocytes and peripheral T cells of transgenic mice: identification of a human CD4 enhancer |
| Q41988156 | Reduced thymic maturation but normal effector function of CD8+ T cells in CD8 beta gene-targeted mice. |
| Q40872594 | Regulated expression of human CD4 rescues helper T cell development in mice lacking expression of endogenous CD4. |
| Q36557490 | Regulation of AP-1 and NFAT transcription factors during thymic selection of T cells |
| Q52199698 | Regulation of LMP2 and TAP1 genes by IRF-1 explains the paucity of CD8+ T cells in IRF-1-/- mice. |
| Q72707290 | Regulation of apoptosis in leukemic cells by analogs of dynemicin A |
| Q43148564 | Regulatory role of leukocyte-common-antigen-related molecule (LAR) in thymocyte differentiation |
| Q67514958 | Repertoire of V alpha and V beta regions of T cell antigen receptors on CD4+ and CD8+ peripheral blood T cells in a novel X-linked combined immunodeficiency disease |
| Q40801703 | Repertoire-determining role of peptide in the positive selection of CD8+ T cells |
| Q36231558 | Requirement for CD8-major histocompatibility complex class I interaction in positive and negative selection of developing T cells |
| Q53496965 | Requirement for Positive Selection of γδ Receptor-Bearing T Cells |
| Q46508660 | Requirement for association of p56lck with CD4 in antigen-specific signal transduction in T cells |
| Q36367266 | Requirement for p56lck tyrosine kinase activation in T cell receptor-mediated thymic selection |
| Q41910605 | Rescue of cytotoxic function in the CD8alpha knockout mouse by removal of MHC class II. |
| Q33908248 | Response of naïve and memory CD8+ T cells to antigen stimulation in vivo |
| Q36370544 | Restricting Zap70 expression to CD4+CD8+ thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection |
| Q73694695 | Reversible activation of c-Myc in thymocytes enhances positive selection and induces proliferation and apoptosis in vitro |
| Q24309394 | Role of CD4 and CD8 in T cell activation and differentiation |
| Q36356408 | Role of CD4 in thymocyte selection and maturation |
| Q43801688 | Role of CD4 molecule in intrathymic T-cell development |
| Q73745038 | Role of CD8beta domains in CD8 coreceptor function: importance for MHC I binding, signaling, and positive selection of CD8+ T cells in the thymus |
| Q37055518 | Selection of intraepithelial lymphocytes with CD8 alpha/alpha co-receptors by self-antigen in the murine gut |
| Q35832518 | Selection of the T-cell repertoire: receptor-controlled checkpoints in T-cell development |
| Q46155874 | Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor |
| Q36361703 | Selective enrichment of major histocompatibility complex class II-specific autoreactive T cells in the thymic Thy0 subset |
| Q51126213 | Selective requirement for MAP kinase activation in thymocyte differentiation. |
| Q38018297 | Self recognition by the immune system |
| Q33794175 | Self-reactive T cells can escape clonal deletion in T-cell receptor V beta 8.1 transgenic mice |
| Q46506862 | Self-reactive gamma delta T cells are eliminated in the thymus |
| Q47631646 | Self-reactivity in thymic double-positive cells commits cells to a CD8 alpha alpha lineage with characteristics of innate immune cells |
| Q59064809 | Self-tolerance to transgenic γδ T cells by intrathymic inactivation |
| Q24302036 | Signal for T-cell differentiation to a CD4 cell lineage is delivered by CD4 transmembrane region and/or cytoplasmic tail |
| Q52217356 | Small CD4+8+TCRlow thymocytes contain precursors of mature T cells. |
| Q35827260 | Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction |
| Q38469675 | Spatial mapping of thymic stromal microenvironments reveals unique features influencing T lymphoid differentiation. |
| Q30434357 | Species specificity and augmentation of responses to class II major histocompatibility complex molecules in human CD4 transgenic mice |
| Q36380824 | Specific activation of the cysteine protease CPP32 during the negative selection of T cells in the thymus. |
| Q41741324 | Specific deletion of the J-C delta locus in murine alpha/beta T cell clones and studies using transgenic mice |
| Q36635313 | Speculations on Mechanisms of HLA Associations with Autoimmune Diseases and the Specificity of "Autoreactive" T Lymphocytes |
| Q72282252 | Spontaneous generation of human CD8+ TCR alpha beta+ cells derived from precursors within the double negative compartment |
| Q42265829 | Stochastic coreceptor shut-off is restricted to the CD4 lineage maturation pathway |
| Q36363495 | Stoichiometry of the T cell antigen receptor (TCR) complex: each TCR/CD3 complex contains one TCR alpha, one TCR beta, and two CD3 epsilon chains |
| Q73835287 | Strength of signaling by CD4 and CD8 coreceptor tails determines the number but not the lineage direction of positively selected thymocytes |
| Q38169708 | Strict Major Histocompatibility Complex Molecule Class-Specific Binding by Co-Receptors Enforces MHC-Restricted αβ TCR Recognition during T Lineage Subset Commitment |
| Q59097178 | Strong xenogeneic HLA response in transgenic mice after introducing an α3 domain into HLA B27 |
| Q36681772 | Structural and functional constraints on HLA class II dimers implicated in susceptibility to insulin dependent diabetes mellitus |
| Q37961459 | Structure and function of the T cell antigen receptor |
| Q68852767 | Study of the thymocyte cell cycle by bivariate analysis of incorporated bromodeoxyuridine and DNA content |
| Q34044419 | Sulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development |
| Q45222694 | Suppression of the immune response by cytotoxic T cells |
| Q36230424 | Surface expression of a T cell receptor beta (TCR-beta) chain in the absence of TCR-alpha, -delta, and -gamma proteins |
| Q73167510 | Surface molecules that drive T cell development in vitro in the absence of thymic epithelium and in the absence of lineage-specific signals |
| Q57719083 | Survival-independent function of NF-κB⧹Rel during late stages of thymocyte differentiation |
| Q57185252 | T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance |
| Q59048606 | T cell depletion in transgenic mice carrying a mutant gene for TCR-β |
| Q40410980 | T cell differentiation: control by the pre-TCR and alpha beta TCR. |
| Q41529750 | T cell receptor (TCR) beta chain homodimers on the surface of immature but not mature alpha, gamma, delta chain deficient T cell lines |
| Q36353463 | T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages |
| Q40854066 | T cell repertoire selection by mouse mammary tumour viruses |
| Q68053766 | T cell subset-specific expression of antigen receptor beta chains in alpha chain-transgenic mice |
| Q33560835 | T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice. |
| Q41441621 | T-call development: is notch a key player in lineage decisions? |
| Q41704753 | T-cell activation. IV. Evidence for a functional linkage between MHC class I, interleukin-2 receptor, and interleukin-4 receptor molecules |
| Q34659128 | T-cell development and the CD4-CD8 lineage decision |
| Q37092026 | T-cell development and transmembrane signaling: changing biological responses through an unchanging receptor |
| Q33540521 | T-cell development: What does Notch do for T cells? |
| Q34038383 | T-cell lineage fate: instructed by receptor signals? |
| Q69099433 | T-cell receptor V beta 5 usage defines reactivity to a human T-cell receptor monoclonal antibody |
| Q40853617 | T-cell receptor repertoire selection by mouse mammary tumor viruses and MHC molecules. |
| Q36931900 | T-cell responsiveness to an oncogenic peripheral protein and spontaneous autoimmunity in transgenic mice |
| Q37628748 | Targeted disruption within the CD3 zeta/eta/phi/Oct-1 locus in mouse |
| Q34418401 | The MHC reactivity of the T cell repertoire prior to positive and negative selection. |
| Q35739633 | The NF-κB1 transcription factor prevents the intrathymic development of CD8 T cells with memory properties |
| Q36362663 | The T cell receptor repertoire of CD4-8+ thymocytes is altered by overexpression of the BCL-2 protooncogene in the thymus |
| Q42618585 | The T-cell repertoire is not dictated by self antigens alone |
| Q87628572 | The ThPOK transcription factor differentially affects the development and function of self-specific CD8(+) T cells and regulatory CD4(+) T cells |
| Q36401807 | The action of Bax and bcl-2 on T cell selection |
| Q41393104 | The agonist-antagonist balance in positive selection. |
| Q36230307 | The appearance of T cells bearing self-reactive T cell receptor in the livers of mice injected with bacteria |
| Q72715937 | The balance between deletion and activation of CD4+8+ thymocytes is controlled by T cell receptor-antigen interactions and is affected by cyclosporin A |
| Q35348304 | The development of functionally responsive T cells |
| Q51081581 | The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate. |
| Q38206218 | The expression of CD4 and CD8 accessory molecules on mature T cells is not random but correlates with the specificity of the alpha beta receptor for antigen |
| Q59073001 | The generation of mature T cells requires interaction of the αβ T-cell receptor with major histocompatibility antigens |
| Q36431046 | The highly alloreactive nature of dual TCR T cells |
| Q37616730 | The human leukocyte antigen (HLA) system: 1990. |
| Q41096340 | The interferon regulatory transcription factor IRF-1 controls positive and negative selection of CD8+ thymocytes. |
| Q36229856 | The kinetics of T cell antigen receptor expression by subgroups of CD4+8+ thymocytes: delineation of CD4+8+3(2+) thymocytes as post-selection intermediates leading to mature T cells |
| Q36361600 | The life span of naive alpha/beta T cells in secondary lymphoid organs |
| Q71708783 | The peripheral T cell repertoire: independent homeostatic regulation of virgin and activated CD8+ T cell pools |
| Q73720189 | The presence and longevity of peripherally expanded donor-derived TCRalphabeta+ mature T lymphocyte clones after allogeneic bone marrow transplantation for adult myeloid leukemias |
| Q24803143 | The quantal theory of how the immune system discriminates between "self and non-self" |
| Q40801736 | The specificity of positive selection: MHC and peptides. |
| Q30443379 | The timing of TCR alpha expression critically influences T cell development and selection |
| Q40905788 | The transcriptional landscape of αβ T cell differentiation |
| Q81483894 | The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection |
| Q24657605 | Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling |
| Q37636838 | Thymic Nurse Cells Participate in Heterotypic Internalization and Repertoire Selection of Immature Thymocytes; Their Removal from the Thymus of Autoimmune Animals May be Important to Disease Etiology |
| Q37869636 | Thymic dendritic cells: phenotype and function |
| Q44794947 | Thymic epithelium induces neither clonal deletion nor anergy to Mls 1a antigens |
| Q35216936 | Thymic generation and regeneration |
| Q33697134 | Thymic nurse cells exhibit epithelial progenitor phenotype and create unique extra-cytoplasmic membrane space for thymocyte selection |
| Q41230457 | Thymic selection defines multiple T cell receptor V beta 'repertoire phenotypes' at the CD4/CD8 subset level |
| Q51161910 | Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage. |
| Q41902311 | Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor |
| Q35076679 | Thymic selection revisited: how essential is it? |
| Q36375680 | Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47 |
| Q38578530 | Thymocyte selection in Vav and IRF-1 gene-deficient mice |
| Q36361553 | Thymus epithelium induces tissue-specific tolerance |
| Q73419066 | Thymus-dependent modulation of Ly49 inhibitory receptor expression on NK1.1+gamma/delta T cells |
| Q36377298 | Thymus-derived glucocorticoids regulate antigen-specific positive selection |
| Q43554100 | Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen |
| Q37551646 | Toward a Molecular Understanding of Adaptive Immunity: A Chronology, Part III. |
| Q36964635 | Transcription of germ line V alpha segments correlates with ongoing T-cell receptor alpha-chain rearrangement |
| Q68059685 | Transgenic T cell receptor interactions in the lymphoproliferative and autoimmune syndromes of lpr and gld mutant mice |
| Q36354116 | Transgenic rearranged T cell receptor gene inhibits lymphadenopathy and accumulation of CD4-CD8-B220+ T cells in lpr/lpr mice |
| Q45203257 | Tyrosine kinase activation in thymic epithelial cells: necessity of thymocyte contact through the gp23/45/90 adhesion complex |
| Q33567980 | Ubc9 Is Required for Positive Selection and Late-Stage Maturation of Thymocytes |
| Q63965623 | Ultrastructural analysis of mouse thymocyte subpopulations |
| Q40922234 | Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation. |
| Q36370932 | Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells |
| Q43654859 | Upregulation of RCAN1 causes Down syndrome-like immune dysfunction. |
| Q52859821 | Variation in human T cell receptor V beta and J beta repertoire: analysis using anchor polymerase chain reaction |
| Q36401225 | Vav regulates peptide-specific apoptosis in thymocytes |
| Q43930610 | Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells |
| Q36401327 | Visualization of CD4/CD8 T cell commitment |
| Q43922688 | Weak positive selection of transgenic T cell receptor-bearing thymocytes: importance of major histocompatibility complex class II, T cell receptor and CD4 surface molecule densities |
| Q37008257 | What do we know about the mechanisms of elimination of autoreactive T and B cells and what challenges remain |
| Q33757632 | Who is in control of the immune system in head and neck cancer? |
| Q41381299 | [EXPRESS] Immune System Involvement in Specific Pain Conditions |
| Q42082679 | c-Myb regulates lineage choice in developing thymocytes via its target gene Gata3. |