| P2093 | author name string | J G Vos | |
| | H J Schuurman | |
| | H Van Loveren | |
| | E J De Waal | |
| P2860 | cites work | Is there an interspecific diversity of the thymic microenvironment? | Q28755253 |
| | Cell death: the significance of apoptosis | Q29617620 |
| | 2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity | Q29618527 |
| | The dendritic cell system and its role in immunogenicity | Q29619870 |
| | The mechanism of action of cyclosporin A and FK506 | Q30014847 |
| | Identification of several cyclosporine binding proteins in lymphoid and non-lymphoid cells in vivo | Q41639911 |
| | Selective elimination of double-positive immature thymocytes by a thymic epithelial cell line | Q41756375 |
| | Immunohistochemical characterization of the thymic microenvironment. A light-microscopic and ultrastructural immunocytochemical study | Q41809415 |
| | An in vitro model for studying the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin to human thymus | Q41838033 |
| | TCDD alters medial epithelial cell differentiation during palatogenesis | Q42198166 |
| | 2,3,7,8-Tetrachlorodibenzo-p-dioxin alters embryonic palatal medial epithelial cell differentiation in vitro | Q42198806 |
| | Early effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on rat thymocytes in vitro | Q42278011 |
| | 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced thymic atrophy and lymphocyte stem cell alterations by mechanisms independent of the estrogen receptor | Q42283203 |
| | The thymus does not mediate 2,3,7,8-tetrachlorodibenzo-p-dioxin-elicited alterations in bone marrow lymphocyte stem cells | Q42284860 |
| | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) enhances terminal differentiation of cultured human epidermal cells | Q42495343 |
| | Role of Fas apoptosis and MHC genes in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immunotoxicity of T cells | Q42555992 |
| | Growth of epithelial cells in the thymic medulla is under the control of mature T cells | Q42769057 |
| | Modulation of cytokeratin expression in the hamster thymus: evidence for a plasticity of the thymic epithelium | Q43088714 |
| | Expression of the alpha beta T-cell receptor is necessary for the generation of the thymic medulla | Q43088727 |
| | Negative selection of precursor thymocytes before their differentiation into CD4+CD8+ cells | Q43454926 |
| | Abnormal thymus development and impaired function of the immune system in rats after prenatal exposure to aciclovir | Q43479160 |
| | Effects of FK506 on rat thymus: time-course analysis by immunoperoxidase technique and flow cytofluorometry | Q43620760 |
| | Effects of subchronic exposure of rats to 2-methoxyethanol or 2-butoxyethanol: Thymic atrophy and immunotoxicity*1 | Q43900339 |
| | Rat embryonic palatal shelves respond to TCDD in organ culture | Q43942629 |
| | Deletion of self-reactive thymocytes occurs at a CD4+8+ precursor stage | Q43960795 |
| | The thymic compartment responsible for positive selection of CD4+ T cells | Q43997933 |
| | Flow cytometric analysis of lymphocyte subpopulations in the spleen and thymus of mice exposed to an acute immunosuppressive dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). | Q44185021 |
| | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) kills glucocorticoid-sensitive thymocytes in vivo | Q44299446 |
| | T-cell maturation and clonal deletion in cyclosporine-induced autoimmunity | Q44359938 |
| | Monoclonal antibodies reactive with subsets of mouse and human thymic epithelial cells | Q44379595 |
| | Toxicity of organotin compounds. I. Atrophy of thymus and thymus-dependent lymphoid tissue in rats fed di-n-octyltindichloride | Q44487237 |
| | Studies on the thymus in Chagas' disease. I. Changes in the thymic microenvironment in mice acutely infected with Trypanosoma cruzi | Q44523989 |
| | T Cell Reactivity to MHC Molecules: Immunity Versus Tolerance | Q44650657 |
| | Inhibition of T cell development in thymic organ culture: implications for the mechanism of action of cyclosporin A. | Q44679467 |
| | Distinct sequence of negative or positive selection implied by thymocyte T-cell receptor densities | Q44704873 |
| | Reversal of ageing changes in the thymus of rats by chemical or surgical castration | Q44767274 |
| | Toxicity of organotin compounds. II. Comparative in vivo and in vitro studies with various organotin and organolead compounds in different animal species with special emphasis on lymphocyte cytotoxicity | Q44802236 |
| | Thymic cortical epithelial cells can present self-antigens in vivo | Q59000144 |
| | Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population | Q59056890 |
| | Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures | Q59070003 |
| | Deletion of self-reactive T cells before entry into the thymus medulla | Q59071302 |
| | Intrathymic presentation of circulating non-major histocompatibility complex antigens | Q59077015 |
| | Post-thymectomy organ-specific autoimmunity: enhancement by cyclosporine A and inhibition by IL-2. | Q34343371 |
| | Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes. | Q34545142 |
| | Pathologic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals | Q34662438 |
| | Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the immune system of laboratory animals | Q34662531 |
| | Innervation of lymphoid organs and implications in development, aging, and autoimmunity | Q35229640 |
| | Do we know the site of action of cyclosporin? | Q35236832 |
| | Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction | Q35319681 |
| | Autologous graft-versus-host disease: a novel approach for antitumor immunotherapy | Q35509744 |
| | The thymic education of developing T cells in self neuroendocrine principles | Q35515149 |
| | Thymic selection: a matter of life and death | Q35650383 |
| | Evidence for a single-niche model of positive selection | Q35930529 |
| | Apoptosis and programmed cell death in immunity | Q36135180 |
| | Thymic endocrinology | Q36268647 |
| | Chemicals trophic for the thymus: risk for immunodeficiency and autoimmunity | Q36268667 |
| | Graft-versus-host disease in cyclosporin A-treated rats after syngeneic and autologous bone marrow reconstitution | Q36347989 |
| | Intrathymic presentation of circulating non-MHC antigens by medullary dendritic cells. An antigen-dependent microenvironment for T cell differentiation | Q36351561 |
| | Age-related factors in cyclosporine-induced syngeneic graft-versus-host disease: regulatory role of marrow-derived T lymphocytes | Q36352047 |
| | Cyclosporine-induced autoimmunity. Conditions for expressing disease, requirement for intact thymus, and potency estimates of autoimmune lymphocytes in drug-treated rats | Q36353085 |
| | Thymus and autoimmunity. Transplantation of the thymus from cyclosporin A-treated mice causes organ-specific autoimmune disease in athymic nude mice | Q36354777 |
| | Development of graft-vs.-host disease-like syndrome in cyclosporine-treated rats after syngeneic bone marrow transplantation. I. Development of cytotoxic T lymphocytes with apparent polyclonal anti-Ia specificity, including autoreactivity | Q36355418 |
| | Requirements for the induction and adoptive transfer of cyclosporine-induced syngeneic graft-versus-host disease | Q36356228 |
| | Seeding of thymic microenvironments defined by distinct thymocyte-stromal cell interactions is developmentally controlled | Q36357252 |
| | Thymus epithelium induces tissue-specific tolerance | Q36361553 |
| | Demonstration of large-scale migration of cortical thymocytes to peripheral lymphoid tissues in cyclosporin A-treated rats. | Q36361927 |
| | The T cell receptor repertoire of CD4-8+ thymocytes is altered by overexpression of the BCL-2 protooncogene in the thymus | Q36362663 |
| | The Ah receptor and the mechanism of dioxin toxicity | Q36390569 |
| | Epithelium-free area in the thymic cortex of rats | Q36511033 |
| | A common stem cell for murine cortical and medullary thymic epithelial cells? | Q36511104 |
| | Differential effects of X-irradiation and cyclosporin-A administration on the thymus with respect to the generation of cyclosporin-A-induced autoimmunity | Q36511119 |
| | Distribution and ultrastructure of S-100-immunoreactive cells in the human thymus | Q36624875 |
| | Fibroblasts can induce thymocyte positive selection in vivo | Q36647981 |
| | T-cell differentiation is influenced by thymic microenvironments | Q37357894 |
| | The role of the T-cell receptor in thymocyte maturation: effects in vivo of anti-receptor antibody | Q37407953 |
| | Regulation of epidermal growth factor binding in a human keratinocyte cell line by 2,3,7,8-tetrachlorodibenzo-p-dioxin | Q44835187 |
| | Enhanced suppression of humoral immunity in DBA2 mice following subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) | Q44895906 |
| | Changes in primary and secondary lymphoid organ T-cell subpopulations resulting from acute in vivo exposure to propanil | Q45081381 |
| | Fetal thymic atrophy after exposure to T-2 toxin: selectivity for lymphoid progenitor cells | Q45092005 |
| | Evidence for a differential avidity model of T cell selection in the thymus | Q45155438 |
| | Effect of cyclosporin A on T cell immunity. II. Defective thymic education of CD4 T helper cell function in cyclosporin A-treated mice | Q45402070 |
| | Inefficient positive selection of T cells directed by haematopoietic cells | Q46211796 |
| | Positive selection of the T cell repertoire: where and when does it occur? | Q46212274 |
| | Reduced T-helper cell function in mice exposed to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin(TCDD) | Q46337868 |
| | Does T-cell tolerance require a dedicated antigen-presenting cell? | Q46491587 |
| | The role of hematogenous and intrinsic precursor cells in lymphocyte production in murine bone marrow and thymus | Q46792029 |
| | Abnormal differentiation of thymocytes in mice treated with cyclosporin A. | Q46966737 |
| | Epithelial cell heterogeneity in mammalian thymus: monoclonal antibody to high molecular weight keratins exclusively binds to Hassall's corpuscles | Q47172889 |
| | Hydrocortisone increases the numbers of KL1+ cells, a discrete thymic epithelial cell subset characterized by high molecular weight cytokeratin expression | Q47176863 |
| | An evaluation of the criterion “Organ weight” under conditions of growth retardation | Q47369501 |
| | Rapid in vivo effects of glucocorticoids on the integrity of rat lymphocyte genomic deoxyribonucleic acid. | Q48391685 |
| | Toxicity of triorganotin compounds: comparative in vivo studies with a series of trialkyltin compounds and triphenyltin chloride in male rats | Q48438833 |
| | The neural and neuro-endocrine component of the human thymus. I. Nerve-like structures | Q48439289 |
| | Effects of two weeks of feed restriction on some common toxicologic parameters in Sprague-Dawley rats | Q48822405 |
| | Triorganotin-induced cytotoxicity to rat thymus, bone marrow and red blood cells as determined by several in vitro assays. | Q50910219 |
| | Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes. | Q51127244 |
| | Another view of the selective model of thymocyte selection. | Q51142565 |
| | Effects of diazepam on cell proliferation in cerebral cortex, anterior pituitary and thymus of developing rats. | Q51793232 |
| | Phenotypic Analysis of Spleen, Thymus, and Peripheral Blood Cells in Aged C57B1/6 Mice Following Long-Term Exposure to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin | Q52053707 |
| | Evidence for the promotion of positive selection of thymocytes by Ah receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin. | Q52204159 |
| | Ontogenic development of murine fetal thymocytes is accelerated by 3,3',4,4'-tetrachlorobiphenyl. | Q52222287 |
| | Positive selection of CD4+ T cells mediated by MHC class II-bearing stromal cell in the thymic cortex. | Q52244580 |
| | Immunotoxicity of tributyltin oxide in rats exposed as adults or pre-weanlings. | Q52245646 |
| | Interdigitating cells and macrophages in the acute involuting rat thymus. An electron-microscopic study on phagocytic activity and population development. | Q52290729 |
| | Mouse monoclonal antibodies against rat major histocompatibility antigens. Two Ia antigens and expression of Ia and class I antigens in rat thymus | Q52833957 |
| | Effect of acyclovir in vitro on lymphopoiesis in the foetal rat thymus | Q53026068 |
| | Effect of six virustatic nucleoside analogues on the development of fetal rat thymus in organ culture | Q53027749 |
| | Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in C57B1/6 mice. | Q53720407 |
| | The cytoarchitecture of the human thymus detected by monoclonal antibodies. | Q53812898 |
| | The comparative toxicity of chlorinated dibenzo-p-dioxins in mice and guinea pigs. | Q53981954 |
| | Toxicity of organotin compounds. III. Suppression of thymus-dependent immunity in rats by di-n-butyltindichloride and di-n-octyltindichloride. | Q53988548 |
| | Assessment of host resistance to Trichinella spiralis in mice following preinfection exposure to 2,3,7,8-TCDD. | Q54212565 |
| | Susceptibility and resistance to cyclosporin A-induced autoimmunity in rats. | Q54254262 |
| | Examination of immune parameters and host resistance mechanisms in B6C3F1 mice following adult exposure to 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin | Q54313505 |
| | Immunotoxicity of bis(tri-n-butyltin)oxide in the rat: effects on thymus-dependent immunity and on nonspecific resistance following long-term exposure in young versus aged rats. | Q54319020 |
| | Induction of graft-versus-host disease after autologous bone marrow transplantation. | Q54355574 |
| | The influence of dexamethasone treatment on the lymphoid and stromal composition of the mouse thymus: a flowcytometric and immunohistological analysis. | Q54419314 |
| | Sensitivity to suppression of cytotoxic T cell generation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on the Ah genotype of the murine host. | Q54481908 |
| | Programmed death of autoreactive thymocytes. | Q54529961 |
| | The effect of thymus environment on T cell development and tolerance | Q56922431 |
| | T cell tolerance by clonal elimination in the thymus | Q56922465 |
| | Ultrastructural analysis of thymic nurse cell epithelium | Q57185485 |
| | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters intrathymic T-cell development in mice | Q57351921 |
| | Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells | Q58991849 |
| | Positive selection of CD4-CD8+ T cells in the thymus of normal mice | Q58993577 |
| | Positive selection of T-lymphocytes induced by intrathymic injection of a thymic epithelial cell line | Q37459622 |
| | A review of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced changes in immunocompetence: 1991 update | Q37505381 |
| | Cyclosporine-induced autoimmunity and immune hyperreactivity | Q37526325 |
| | Adhesion of immature thymocytes to thymic stromal cells through fibronectin molecules and its significance for the induction of thymocyte differentiation | Q37541265 |
| | Kinetics of mature T-cell development in the thymus | Q37730111 |
| | Phenotypic and functional stages in the intrathymic development of alpha beta T cells | Q37769126 |
| | Towards an integrated view of thymopoiesis | Q37769128 |
| | 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced changes in immunocompetence: possible mechanisms | Q37774154 |
| | Thymic dendritic cells: phenotype and function | Q37869636 |
| | Death and transfiguration of cortical thymocytes: a reconsideration | Q37923402 |
| | The thymus selects the useful, neglects the useless and destroys the harmful | Q38255315 |
| | The Ah locus: genetic differences in toxicity, cancer, mutation, and birth defects | Q38317576 |
| | Characterization of an antigenic determinant preferentially expressed by type I epithelial cells in the murine thymus | Q38524737 |
| | Toxicity of dibutyltin, tributyltin and other organotin compounds to humans and to experimental animals | Q38628934 |
| | Cyclosporine | Q38733507 |
| | T cell selection in the thymus | Q39633830 |
| | The T cell receptor | Q39682077 |
| | Dynamics of early T cells: prothymocyte migration and proliferation in the adult mouse thymus | Q39739345 |
| | The effects of cyclosporin A on the immune system | Q39849792 |
| | Thymus Independence, Kinetics and Phagocytic Ability of Interdigitating Cells | Q40119008 |
| | Cyclosporine: immunology, toxicity and pharmacology in experimental animals | Q40200051 |
| | Relation between langerhans cells, veiled cells, and interdigitating cells | Q40334266 |
| | Pathology of the thymus: Changes induced by xenobiotics and gene targeting | Q40423253 |
| | Investigations on the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on parameters of various immune functions | Q40599051 |
| | Death and T cells | Q40618204 |
| | A differential-avidity model for T-cell selection | Q40626070 |
| | Thymic education--T cells do it for themselves | Q40668164 |
| | Crosstalk in the mouse thymus | Q40668183 |
| | The ultrastructure of the normal human thymus: A study of 36 cases | Q40673182 |
| | The role of brain-immune interactions in immunotoxicology | Q40675437 |
| | Immunotoxic organotins as possible model compounds in studying apoptosis and thymocyte differentiation | Q40688324 |
| | Immune suppression as a consequence of a selective cytotoxic activity of certain organometallic compounds on thymus and thymus-dependent lymphocytes | Q40714111 |
| | Histopathology of the immune system as a tool to assess immunotoxicity. | Q40725139 |
| | The thymic microenvironment. | Q40769611 |
| | Development in the thymus: it takes two to tango | Q40769624 |
| | Positive selection of TcR alpha beta thymocytes: is cortical thymic epithelium an obligatory participant in the presentation of major histocompatibility complex protein? | Q40801698 |
| | The identity of the cells that positively select thymocytes | Q40801718 |
| | Positive selection of immature alpha beta T cells | Q40801741 |
| | Positive selection of lymphocytes | Q40807424 |
| | Negative selection of lymphocytes | Q40807431 |
| | The Ah receptor: mediator of the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds | Q40815544 |
| | Development of alpha beta T cells | Q40854704 |
| | Cyclosporin binding proteins. Identification, distribution, function and relation to FK binding proteins | Q40856603 |
| | The role of chemical-induced stress responses in immunosuppression: a review of quantitative associations and cause-effect relationships between chemical-induced stress responses and immunosuppression | Q40911227 |
| | The thymic repertoire of neuroendocrine self-antigens: physiological implications in T-cell life and death. | Q41078409 |
| | Rescue of thymocytes and T cell hybridomas from glucocorticoid-induced apoptosis by stimulation via the T cell receptor/CD3 complex: a possiblein vitro model for positive selection of the T cell repertoire | Q41152049 |
| | The role of the T cell receptor in positive and negative selection of developing T cells | Q41174331 |
| | The human thymic microenvironment: thymic epithelium contains specific keratins associated with early and late stages of epidermal keratinocyte maturation | Q41246411 |
| | Response of murine epidermal keratinocyte cultures to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): comparison of haired and hairless genotypes | Q41249634 |
| | Dendritic cells: from ontogenetic orphans to myelomonocytic descendants. | Q41266906 |
| | Presentation of antigen, foreign major histocompatibility complex proteins and self by thymus cortical epithelium | Q41325052 |
| | The thymus atrophy-inducing organotin compound dbtc inhibits the binding of thymocytes to thymic epithelial cells | Q41354858 |
| | Regulation of gene expression and acceleration of differentiation in human keratinocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin | Q41450455 |
| | A thymic epithelial cell line induces both positive and negative selection in the thymus. | Q41490895 |
| | In vitro negative selection of alpha beta T cell receptor transgenic thymocytes by conditionally immortalized thymic cortical epithelial cell lines and dendritic cells | Q41522244 |
| | Positive selection of T lymphocytes on fibroblasts | Q41534256 |
| | Thymic involution in rats given diets containing dioctyltin dichloride | Q41586001 |
| | Induction of terminal differentiation in cultured human keratinocytes by polychlorinated aromatic hydrocarbons as measured by cell size analysis | Q41630953 |
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cyclosporine | Q367700 |
| P304 | page(s) | 381-430 | |
| P577 | publication date | 1997-07-01 | |
| P1433 | published in | Critical Reviews in Toxicology | Q3562267 |
| P1476 | title | Differential effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin, bis(tri-n-butyltin) oxide and cyclosporine on thymus histophysiology | |
| P478 | volume | 27 | |