| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/0092-8674(94)90331-X |
| P698 | PubMed publication ID | 8293461 |
| P50 | author | Gustav Nossal | Q1556241 |
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 229-239 | |
| P577 | publication date | 1994-01-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Cell | Q655814 |
| P1476 | title | Negative selection of lymphocytes | |
| P478 | volume | 76 |
| Q73568263 | 7α‐Hydroxylation and 3‐Dehydrogenation Abolish the Ability of 25‐Hydroxycholesterol and 27‐Hydroxycholesterol to Induce Apoptosis in Thymocytes |
| Q42945090 | A Fail-safe Mechanism for Negative Selection of Isotype-switched B Cell Precursors Is Regulated by the Fas/FasL Pathway |
| Q36551440 | A Myc-associated zinc finger protein binding site is one of four important functional regions in the CD4 promoter |
| Q42971592 | A Role for Fas in Negative Selection of Thymocytes In Vivo |
| Q77372675 | A caspase inhibitor protects thymocytes from diverse signal-mediated apoptosis but not from clonal deletion in fetal thymus organ culture |
| Q40017390 | A central role for a single c-Myb binding site in a thymic locus control region |
| Q74825850 | A defect in central tolerance in NOD mice |
| Q41107303 | A high affinity T cell receptor? |
| Q30448835 | A lung-specific neo-antigen elicits specific CD8+ T cell tolerance with preserved CD4+ T cell reactivity. Implications for immune-mediated lung disease |
| Q57305051 | A mechanism of T cell dependent selection of antigen engaged Germinal Center B cells |
| Q71976536 | A monoclonal antibody against a murine CD38 homologue delivers a signal to B cells for prolongation of survival and protection against apoptosis in vitro: unresponsiveness of X-linked immunodeficient B cells |
| Q36369498 | A naturally processed mitochondrial self-peptide in complex with thymic MHC molecules functions as a selecting ligand for a viral-specific T cell receptor |
| Q42943299 | A novel function of CD40: induction of cell death in transformed cells |
| Q28505565 | A novel gene product that couples TCR signaling to Fas(CD95) expression in activation-induced cell death |
| Q77394137 | A novel immunosuppressant, FTY720, increases the efficiency of a superantigen-induced peripheral T-cell deletion whilst inhibiting negative selection in the thymus |
| Q36365625 | A pathway of costimulation that prevents anergy in CD28- T cells: B7-independent costimulation of CD1-restricted T cells |
| Q33816818 | A portrait of the Bcl-2 protein family: life, death, and the whole picture |
| Q42058596 | A potential role for Elf-1 in CD4 promoter function |
| Q42165830 | A regulatory role for TRAF1 in antigen-induced apoptosis of T cells. |
| Q28285957 | Abnormal in vitro thymocyte differentiation in a patient with severe combined immunodeficiency-Nezelof's syndrome |
| Q40624666 | Absence of Programmed Death Receptor 1 Alters Thymic Development and Enhances Generation of CD4/CD8 Double-Negative TCR-Transgenic T Cells |
| Q36366097 | Activation and negative selection of functionally distinct subsets of antibody-secreting cells by influenza hemagglutinin as a viral and a neo-self antigen. |
| Q35119889 | Activation of Rheumatoid Factor (RF) B Cells and Somatic Hypermutation Outside of Germinal Centers in Autoimmune‐Prone MRL/lpr Mice |
| Q73228067 | Activation-induced T cell death occurs at G1A phase of the cell cycle |
| Q42731034 | Adaptive immunity: Based on the dual recognition responses of αβT cells |
| Q71425950 | Administration of anti-interleukin-2 receptor alpha antibody in vivo induces localized autoimmune disease |
| Q40380711 | Advances in selective immunosuppression. |
| Q37164758 | Advances in type I diabetes associated tolerance mechanisms |
| Q77135735 | Alterations in Early Biochemical Events Following T Cell Activation in Leprosy Patients |
| Q34982958 | Altered positive selection due to corecognition of floppy peptide/MHC II conformers supports an integrative model of thymic selection |
| Q36400982 | An Alternate Pathway for T Cell Development Supported by the Bone Marrow Microenvironment: Recapitulation of Thymic Maturation |
| Q39804843 | An acetylcholine receptor alpha subunit promoter confers intrathymic expression in transgenic mice. Implications for tolerance of a transgenic self-antigen and for autoreactivity in myasthenia gravis |
| Q35834615 | An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis |
| Q37107172 | An introduction to biomaterial-based strategies for curbing autoimmunity |
| Q41315932 | Antigen receptor‐initiated growth inhibition is blocked in CD45‐loss variants of a mature B lymphoma, with limited effects on apoptosis |
| Q41049050 | Apoptosis and the maintenance of homoeostasis in the immune system |
| Q34096282 | Apoptosis genes and autoimmunity. |
| Q39797408 | Apoptosis signal-regulating kinase (ASK)-1 mediates apoptosis through activation of JNK1 following engagement of membrane immunoglobulin. |
| Q34281774 | Apoptosis-linked gene 2-deficient mice exhibit normal T-cell development and function |
| Q71066513 | Asymmetric redundancy in CD4 silencer function |
| Q34299389 | Autoantibodies in the diagnosis of systemicrheumatic diseases |
| Q36362953 | Autoimmunity and apoptosis |
| Q41279358 | Autoreactive T cells in healthy individuals show tolerance in vitro with characteristics similar to but distinct from clonal anergy |
| Q40460122 | B Cell Activation and Apoptosis |
| Q39297230 | B Cell Development in the Bone Marrow Is Regulated by Homeostatic Feedback Exerted by Mature B Cells |
| Q28298373 | B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins |
| Q53643439 | B cells from aged mice exhibit reduced apoptosis upon B-cell antigen receptor stimulation and differential ability to up-regulate survival signals |
| Q28203083 | BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes |
| Q52040363 | Bcl-2 Obstructs Negative Selection of Autoreactive, Hypermutated Antibody V Regions during Memory B Cell Development |
| Q28513839 | Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice |
| Q36365670 | Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice |
| Q41522438 | Bcl-x and the regulation of survival in the immune system. |
| Q42664386 | Blocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor. |
| Q71169434 | CD4 T cell tolerance to nuclear proteins induced by medullary thymic epithelium |
| Q34012863 | CD4+CD25+ regulatory T cells in autoimmune arthritis |
| Q52518610 | CD4-negative cytotoxic T cells with a T cell receptor alpha/beta intermediate expression in CD8-deficient mice. |
| Q90339934 | CXCR5+PD-1+ follicular helper CD8 T cells control B cell tolerance |
| Q28343342 | Calcineurin and vacuolar-type H+-ATPase modulate macrophage effector functions |
| Q44179114 | Caspase cleavage of the transcription factor FLI-1 during preB leukemic cell death. |
| Q67531415 | Cell Death in Development |
| Q39277510 | Cell death and thymic tolerance |
| Q42474645 | Cell death in the olfactory epithelium |
| Q41514584 | Cell death in the regulation of immune responses |
| Q41098056 | Central tolerance of T cells |
| Q40621593 | Changes in bad phosphorylation are correlated with BCR-induced apoptosis of WEHI-231 immature B cells. |
| Q48548636 | Characterisation of CD8 monoclonal antibody-induced protection from diabetes in NOD mice |
| Q28144444 | Characterization of the insulin-like growth factor axis in the human thymus |
| Q33648107 | Cloning and comparative analysis of the human pre-T-cell receptor alpha-chain gene |
| Q40875558 | Comparison of signaling pathways involved in apoptosis of a thymocyte hybridoma triggered by a rat thymic medullary epithelial cell line, dexamethasone or T-cell receptor cross-linking |
| Q44442942 | Con A activates an Akt/PKB dependent survival mechanism to modulate TCR induced cell death in double positive thymocytes. |
| Q33534182 | Conceptual shifts in immunology: comments on the "two-way paradigm". |
| Q41872230 | Conditional Fas-associated death domain protein (FADD): GFP knockout mice reveal FADD is dispensable in thymic development but essential in peripheral T cell homeostasis |
| Q33890366 | Conference highlight: do T cells care about the mitogen-activated protein kinase signalling pathways? |
| Q40805330 | Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders. |
| Q36366830 | Constitutive expression of bcl-2 in B cells causes a lethal form of lupuslike autoimmune disease after induction of neonatal tolerance to H-2b alloantigens |
| Q47593380 | Contribution of alphabeta and gammadelta T cells to the generation of primary immunoglobulin G-driven autoimmune response in immunoglobulin- mu-deficient/lpr mice |
| Q36365305 | Control of CD4 effector fate: transforming growth factor beta 1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion |
| Q35623006 | Control of autoimmunity by naturally arising regulatory CD4+ T cells |
| Q44927725 | Covalent modification as a mechanism for the breakdown of immune tolerance to pyruvate dehydrogenase complex in the mouse. |
| Q37207024 | Critical Role of B Cell Lymphoma 10 in BAFF-Regulated NF-κB Activation and Survival of Anergic B Cells |
| Q47727394 | Crossroads of extrathymic lymphocytes maturation pathways |
| Q21328691 | Current hypotheses on how microsatellite instability leads to enhanced survival of Lynch Syndrome patients |
| Q48049861 | Cyclin G2 is up-regulated during growth inhibition and B cell antigen receptor-mediated cell cycle arrest |
| Q40949947 | Death signals from the B cell antigen receptor target mitochondria, activating necrotic and apoptotic death cascades in a murine B cell line, WEHI-231. |
| Q30193572 | Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes |
| Q42815571 | Deletion of SHIP or SHP-1 Reveals Two Distinct Pathways for Inhibitory Signaling |
| Q40996721 | Deletional and mutational analyses of the human CD4 gene promoter: characterization of a minimal tissue-specific promoter. |
| Q34982085 | Dendritic cell control of tolerogenic responses |
| Q77879066 | Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition |
| Q28144319 | Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor |
| Q37174048 | Development of monoclonal antibodies to detect bovine FOXP3 in PBMCs exposed to a staphylococcal superantigen |
| Q47700492 | Development of t-cells during fish embryogenesis |
| Q51127244 | Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes |
| Q52190945 | Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection. |
| Q36401538 | Differential Effect of B Lymphocyte–induced Maturation Protein (Blimp-1) Expression on Cell Fate during B Cell Development |
| Q41570922 | Differential Effects of 2,3,7,8-Tetrachlorodibenzo-P-Dioxin,bis(Tri-N-Butyltin)Oxide and Cyclosporine on Thymus Histophysiology |
| Q41522446 | Differentiation and apoptosis of human germinal center B-lymphocytes |
| Q73318768 | Do holes in the T-cell repertoire have a center-surround regulatory structure? A rationale for the bifurcation of the Th1 and Th2 pathways of differentiation |
| Q73814879 | Double-positive T cell receptor(high) thymocytes are resistant to peptide/major histocompatibility complex ligand-induced negative selection |
| Q40465770 | Dual receptor T-cells. Implications for alloreactivity and autoimmunity. |
| Q47727264 | Effects of carrier and hapten array on the production of anti‐hapten antibodies analyzed by two‐dimensional affinity electrophoresis |
| Q36684935 | Emergence in C kappa knockout mice of a diverse cytotoxic T lymphocyte repertoire that recognizes a single peptide from the immunoglobulin constant kappa light chain region. |
| Q41383380 | Endogenous antigen presentation by autoantigen-transfected Epstein-Barr virus-lymphoblastoid cells: T cell receptor N-region hydrophobicity relates to thyroid antigen recognition |
| Q33582372 | Endogenous c-src as a determinant of the tumorigenicity of src oncogenes |
| Q36380837 | Enforced Bcl-2 expression inhibits antigen-mediated clonal elimination of peripheral B cells in an antigen dose-dependent manner and promotes receptor editing in autoreactive, immature B cells |
| Q31004523 | Evidence for a bias toward intracellular antigens in the local humoral anti-tumor immune response of a colorectal cancer patient revealed by phage display |
| Q73925023 | Evidence that non-deletional mechanisms are responsible for inducing and maintaining unresponsiveness after intrathymic injection of non-professional antigen presenting cells |
| Q91935600 | Examining pathogenic concepts of autoimmune hepatitis for cues to future investigations and interventions |
| Q41289542 | Expression and function of the murine CD95/FasR/APO‐1 receptor in relation to B cell ontogeny |
| Q73359138 | Expression of activated CDC42 induces T cell apoptosis in thymus and peripheral lymph organs via different pathways |
| Q36857485 | Expression of apoptosis regulators in germinal centers and germinal center-derived B-cell lymphomas: insight into B-cell lymphomagenesis |
| Q71011992 | Expression of bcl-x during mouse B cell differentiation and following activation by various stimuli |
| Q73867620 | Expression of intestine-specific antigen reveals novel pathways of CD8 T cell tolerance induction |
| Q28146131 | Expression of the Bcl-2 family member A1 is developmentally regulated in T cells |
| Q36401145 | Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance |
| Q34507508 | Facilitation of beta selection and modification of positive selection in the thymus of PD-1-deficient mice |
| Q54232262 | Failure of blood-thymus barrier as a mechanism of tumor and trophoblast escape |
| Q73295941 | Failure to down-regulate Bcl-2 protein in thymic germinal center B cells in myasthenia gravis |
| Q39018355 | Fas ligation induces apoptosis of CD40-activated human B lymphocytes |
| Q47320235 | FcgammaRIIB is differentially expressed during B cell maturation and in B-cell lymphomas. |
| Q40431523 | Follicular Dendritic Cells: Origin and Function |
| Q38569164 | Food-Nonfood Discrimination in Ancestral Vertebrates: Gamete Cannibalism and the Origin of the Adaptive Immune System |
| Q40495493 | From AIDS to parasite infection: pathogen-mediated subversion of programmed cell death as a mechanism for immune dysregulation |
| Q41561675 | From stem cells to lymphocytes: biology and transplantation |
| Q48495983 | From variation in genetic information to clonal deletion: Joshua Lederberg's immunological legacy |
| Q40913568 | Functional aspects of apoptosis in hematopoiesis and consequences of failure |
| Q33898975 | Functional dissection of BCR signaling pathways |
| Q28591401 | Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis |
| Q74328329 | Functionally and phenotypically mature mouse CD8+ T cells develop in porcine thymus grafts in mice |
| Q33646713 | Galectins: a key intersection between glycobiology and immunology |
| Q54198120 | Gamma delta and alpha beta T cells are equally susceptible to apoptosis |
| Q40927315 | Genetic background and environment contribute synergistically to the onset of autoimmune diseases |
| Q36365389 | Genetic basis for T cell recognition of a major histocompatibility complex class II-restricted neo-self peptide |
| Q28275284 | Genetic divergence of the rhesus macaque major histocompatibility complex |
| Q41105707 | Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor |
| Q40910237 | Genetic vaccines — a revolution in vaccinology? |
| Q28504958 | H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection |
| Q42942993 | HIVgp120 activates autoreactive CD4-specific T cell responses by unveiling of hidden CD4 peptides during processing |
| Q37888244 | HLA class I-associated diseases with a suspected autoimmune etiology: HLA-B27 subtypes as a model system |
| Q40648771 | Heat shock proteins in immune response to cancer: the Fourth Paradigm |
| Q77589702 | Helix-loop-helix proteins regulate pre-TCR and TCR signaling through modulation of Rel/NF-kappaB activities |
| Q36401743 | Heteroclitic immunization induces tumor immunity |
| Q35675262 | Heteroclitic proliferative responses and changes in cytokine profile induced by altered peptides: Implications for autoimmunity |
| Q34378731 | How specificity for self-peptides shapes the development and function of regulatory T cells |
| Q37499321 | How the immune system achieves self-nonself discrimination during adaptive immunity |
| Q52045269 | Human leukocyte antigen phenotype imposes complex constraints on the antigen-specific cytotoxic T lymphocyte repertoire |
| Q36364533 | Human thymic epithelial cells express an endogenous lectin, galectin-1, which binds to core 2 O-glycans on thymocytes and T lymphoblastoid cells |
| Q37349221 | Hyperresponse to T-cell receptor signaling and apoptosis of Id1 transgenic thymocytes |
| Q71047954 | Identification and characterization of a human CD4 silencer |
| Q36366113 | Ig-specific T cell receptor-transgenic T cells are not deleted in the thymus and are functional in vivo |
| Q35766216 | Immune Regulation through Mitochondrion-Dependent Dendritic Cell Death Induced by T Regulatory Cells |
| Q38307341 | Immune cellular regulation on autoantibody production in pemphigus |
| Q41112926 | Immune evasion strategies of the herpesviruses |
| Q77925665 | Immune privilege in the retina |
| Q41710713 | Immune recognition of influenza hemagglutinin as a viral and a neo-self-antigen |
| Q35155936 | Immune responsiveness, tolerance and dsRNA: implications for traditional paradigms |
| Q45870660 | Immune tolerance induced by platelet-targeted factor VIII gene therapy in hemophilia A mice is CD4 T cell mediated |
| Q34288468 | Immunity to cancer through immune recognition of altered self: studies with melanoma |
| Q33824735 | Immunology: improving on nature in the twenty-first century |
| Q37901992 | Immunophysiology and Pathology of Inflammation in the Testis and Epididymis |
| Q40927838 | Immunotolerance and prevention of ocular autoimmune disease |
| Q74534866 | Importance of thymus to maintain operational tolerance to fully allogeneic cardiac grafts |
| Q73075164 | Induction of thymic tolerance as possibility in prevention of recurrent spontaneous abortion |
| Q71047930 | Inhibition of I-Ad-, but not Db-restricted peptide-induced thymic apoptosis by glucocorticoid receptor antagonist RU486 in T cell receptor transgenic mice |
| Q36366355 | Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self-reactive T cells |
| Q33653653 | Inhibitory pathways triggered by ITIM-containing receptors. |
| Q41500820 | Initiation of autoimmunity to self-proteins complexed with viral antigens |
| Q73855748 | Innate Natural Antibodies. Primary Roles Indicated by Specific Epitopes |
| Q24599847 | Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis |
| Q51125242 | Intrathymic T cell receptor (TcR) targeting in mice lacking CD4 or major histocompatibility complex (MHC) class II: rescue of CD4 T cell lineage without co-engagement of TcR/CD4 by MHC class II. |
| Q52197567 | Kinetics of Fas-induced apoptosis in thymic organ culture |
| Q77436009 | Level of HgCl2-mediated phosphorylation of intracellular proteins determines death of thymic T-lymphocytes with or without DNA fragmentation |
| Q40414738 | Lifespan of lymphocytes |
| Q71868788 | Lipopolysaccharide prevents apoptosis and induces responsiveness to antigen receptor cross-linking in immature B cells |
| Q36371743 | Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells |
| Q47320212 | Low molecular weight antigen arrays delete high affinity memory B cells without affecting specific T-cell help |
| Q37388197 | Low-affinity peptides and T-cell selection |
| Q40455971 | Lymphocyte Development: Intrinsic checkpoints for lineage progression |
| Q60998068 | MHC antigens in interferon γ (IFNγ) receptor deficient mice: IFNγ-independent up-regulation of MHC class II in renal tubules |
| Q40413347 | MHC diversity and selection |
| Q73396262 | Magnitude of protein tyrosine phosphorylation-linked signals determines growth versus death of thymic T lymphocytes |
| Q47917801 | Malaria associated apoptosis is not significantly correlated with either parasitemia or the number of previous malaria attacks |
| Q41881444 | Mature T cell reactivity altered by peptide agonist that induces positive selection |
| Q35670840 | Mechanisms of genetic susceptibility to type I diabetes: beyond HLA. |
| Q35176310 | Mechanisms, manifestations, and failures of self-tolerance |
| Q33908599 | Modulation of immune function by dietary lectins in rheumatoid arthritis |
| Q33604355 | Molecular analysis of immunoglobulin genes in multiple myeloma |
| Q37209084 | Molecular cloning and characterisation of the rock bream, Oplegnathus fasciatus, Fas (CD95/APO-1), and its expression analysis in response to bacterial or viral infection |
| Q34436005 | Molecular mimicry and clonal deletion: A fresh look |
| Q33630981 | Molecular mimicry and multiple sclerosis: degenerate T-cell recognition and the induction of autoimmunity |
| Q40653042 | Molecular mimicry: can epitope mimicry induce autoimmune disease? |
| Q36363807 | Murine B cell proliferation and protection from apoptosis with an antibody against a 105-kD molecule: unresponsiveness of X-linked immunodeficient B cells |
| Q36371320 | Mutation in fas ligand impairs maturation of thymocytes bearing moderate affinity T cell receptors |
| Q43822883 | NF kappa B controls the balance between Fas and tumor necrosis factor cell death pathways during T cell receptor-induced apoptosis via the expression of its target gene A20. |
| Q77990075 | Natural and induced apoptosis during lymphocyte development in the axolotl |
| Q74460566 | Natural autoantibodies and complement promote the uptake of a self antigen, human thyroglobulin, by B cells and the proliferation of thyroglobulin-reactive CD4(+) T cells in healthy individuals |
| Q42947706 | Negative selection in the thymus includes semimature T cells |
| Q42154454 | Negative selection of human germinal center B cells by prolonged BCR cross-linking |
| Q41284955 | Negative signaling in B cells by surface immunoglobulins |
| Q74657062 | Neuroendocrine Control of the Thymusa |
| Q36364722 | Normal T lymphocytes can express two different T cell receptor beta chains: implications for the mechanism of allelic exclusion |
| Q73070855 | Not just another Fab: the crystal structure of a TcR-MHC-peptide complex |
| Q41563476 | Ontogeny of Human Natural and Acquired Immunity |
| Q40913310 | Optimal activation of tumor-reactive T cells by selected antigenic peptide analogues. |
| Q34054880 | Origin and diversification of the clonogenic cell in multiple myeloma: lessons from the immunoglobulin repertoire |
| Q33930556 | Paradoxical intrathymic positive selection in mice with only a covalently presented agonist peptide |
| Q41514577 | Pathways leading to cell death in T cells |
| Q42065157 | Peripheral tolerance in T cell receptor-transgenic mice: evidence for T cell anergy |
| Q57258533 | Peripheral tolerance of CD4 T cells following local activation in adolescent mice |
| Q36377290 | Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB. |
| Q40765687 | Phorbol 12-myristate 13-acetate inhibits death receptor-mediated apoptosis in Jurkat cells by disrupting recruitment of Fas-associated polypeptide with death domain |
| Q42124822 | Phospholipase Cgamma2 contributes to light-chain gene activation and receptor editing |
| Q72614802 | Polyreactive IgM antibodies in the circulation are masked by antigen binding |
| Q28116470 | Positional cloning of the APECED gene |
| Q73691807 | Positive and negative thymic selection in T cell receptor‐transgenic mice correlate with Nur77 mRNA expression |
| Q47849301 | Posttranslational protein modifications, apoptosis, and the bypass of tolerance to autoantigens |
| Q36375444 | Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros |
| Q36370766 | Preferential signaling and induction of allergy-promoting lymphokines upon weak stimulation of the high affinity IgE receptor on mast cells. |
| Q60420174 | Probing the mechanisms of low immunogenicity of a lipocalin allergen, Bos d 2, in a mouse model |
| Q41711455 | Programmed B and T Cell Development |
| Q37773421 | Programmed cell death of dendritic cells in immune regulation |
| Q55035366 | Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. |
| Q40493317 | Prospects for induction of tolerance in renal transplantation |
| Q41844970 | Pulsing with blast cell lysate or blast-derived total RNA reverses the dendritic cell-mediated cytotoxic activity of cytokine-induced killer cells against allogeneic acute myelogenous leukemia cells |
| Q36376530 | Quantitative impact of thymic clonal deletion on the T cell repertoire |
| Q71740162 | Raf regulates positive selection |
| Q35763831 | Rat stem cells developing in irradiated SCID mice fail to become tolerized and cause lethal graft-versus-host disease |
| Q41168240 | Reactivity and specificity of CD8+ T cells in mice with defects in the MHC class I antigen-presenting pathway |
| Q77355819 | Recent Progress on the Regulation of Apoptosis by Bcl-2 Family Members |
| Q42367245 | Recent advances in understanding autoimmune thyroid disease: the tallest tree in the forest of polyautoimmunity. |
| Q33932667 | Receptor selection in B and T lymphocytes |
| Q35919783 | Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway |
| Q37009989 | Regulation of Apoptosis by Gram-Positive Bacteria: Mechanistic Diversity and Consequences for Immunity |
| Q34424352 | Regulation of cell survival and death during Flavivirus infections |
| Q36555939 | Regulation of the Nur77 orphan steroid receptor in activation-induced apoptosis |
| Q35621984 | Regulatory T cells for tolerance therapy: revisiting the concept |
| Q40226369 | Requirement for JNK-dependent upregulation of BimL in anti-IgM-induced apoptosis in murine B lymphoma cell lines WEHI-231 and CH31. |
| Q36367266 | Requirement for p56lck tyrosine kinase activation in T cell receptor-mediated thymic selection |
| Q40965128 | Requirement of PEST domain tyrosine phosphatase PEP in B cell antigen receptor-induced growth arrest and apoptosis |
| Q45711516 | Requirement of c-Jun N terminal kinase and P38 mitogen-activated protein kinase for anti-IgM-induced reduction in mitochondrial membrane potential in CH31 B lymphoma cells |
| Q41290962 | Requirement of phospholipase C-gamma 2 activation in surface immunoglobulin M-induced B cell apoptosis. |
| Q26852927 | Resolve, revise, and relax: The 3 Rs of B cell repertoire adjustment |
| Q34044230 | Restoration of surface IgM-mediated apoptosis in an anti-IgM-resistant variant of WEHI-231 lymphoma cells by HS1, a protein-tyrosine kinase substrate |
| Q42805400 | Retrovirus mediated gene transfer of the self antigen MBP into the bone marrow of mice alters resistance to experimental autoimmune encephalomyelitis |
| Q41175980 | Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor |
| Q40139773 | Role for Btg1 and Btg2 in growth arrest of WEHI-231 cells through arginine methylation following membrane immunoglobulin engagement |
| Q41042940 | SHIP Modulates Immune Receptor Responses by Regulating Membrane Association of Btk |
| Q77994482 | SHIP recruitment attenuates Fc gamma RIIB-induced B cell apoptosis |
| Q28658418 | Selection of apoptotic cell specific human antibodies from adult bone marrow |
| Q36366862 | Selective activation of Fas/Fas ligand-mediated cytotoxicity by a self peptide |
| Q36367455 | Selective activation of the calcium signaling pathway by altered peptide ligands |
| Q42942821 | Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody |
| Q51126213 | Selective requirement for MAP kinase activation in thymocyte differentiation |
| Q47713262 | Self-reactive B lymphocytes overexpressing Bcl-xL escape negative selection and are tolerized by clonal anergy and receptor editing. |
| Q40373293 | Self-tolerance checkpoints in B lymphocyte development |
| Q41642426 | Serological identification of human tumor antigens |
| Q35124060 | Sertoli cell-specific deletion of the androgen receptor compromises testicular immune privilege in mice |
| Q28591321 | Several different cell surface molecules control negative selection of medullary thymocytes |
| Q40500421 | Signal transduction by the antigen receptors of B and T lymphocytes. |
| Q35666703 | Signaling in transitional type 2 B cells is critical for peripheral B-cell development |
| Q24305300 | Siva-1 negatively regulates NF-kappaB activity: effect on T-cell receptor-mediated activation-induced cell death (AICD) |
| Q35670133 | Siva-1 promotes K-48 polyubiquitination of TRAF2 and inhibits TCR-mediated activation of NF-kappaB. |
| Q41711130 | Somatic Mutagenesis and Evolution of Memory B Cells |
| Q42678196 | Somatic hypermutation of immunoglobulin variable region genes: focus on follicular lymphoma and multiple myeloma |
| Q43780118 | Somatic hypermutation targeting to intrinsic hotspots of immunoglobulin genes in follicular lymphoma and multiple myeloma |
| Q73170826 | Split tolerance to the MHC class I molecule H-2Dd in animals transgenic for its soluble analog |
| Q34602699 | Structural basis of T cell recognition of peptides bound to MHC molecules |
| Q77158682 | Structural principles that govern the peptide-binding motifs of class I MHC molecules |
| Q40894111 | Structurally diverse forms of HLA-B27 molecules are displayed in vivo in a cell type-dependent manner |
| Q40976416 | Studying immunological tolerance by physically monitoring antigen-specific T cells in vivo |
| Q36375090 | Subclass-specific nuclear localization of a novel CD4 silencer binding factor |
| Q41269709 | Superantigens in insulin-dependent diabetes mellitus |
| Q41864164 | Survival of Mature CD4 T Lymphocytes Is Dependent on Major Histocompatibility Complex Class II–expressing Dendritic Cells |
| Q36380957 | T Cell Receptor Signals Enhance Susceptibility to Fas-mediated Apoptosis |
| Q45960009 | T Cell Tolerance and the Thymusa |
| Q40379095 | T cell development in CD3-zeta mutant mice |
| Q36365637 | T cell receptor repertoire for a viral epitope in humans is diversified by tolerance to a background major histocompatibility complex antigen |
| Q36364509 | T cell receptor-mediated signaling events in CD4+CD8+ thymocytes undergoing thymic selection: requirement of calcineurin activation for thymic positive selection but not negative selection. |
| Q40434757 | T cell repertoire usage in humans, from newborns to centenarians |
| Q34031721 | T cell-intrinsic and -extrinsic contributions of the IFNAR/STAT1-axis to thymocyte survival. |
| Q33632307 | T-cell development: a role for self-peptides in positive selection |
| Q33886507 | T-cell receptor ligation by peptide/MHC induces activation of a caspase in immature thymocytes: the molecular basis of negative selection. |
| Q28141432 | T-cell receptors and autoimmune thyroid disease--signposts for T-cell-antigen driven diseases |
| Q41441623 | T-cell receptors: is the repertoire inherently MHC-specific? |
| Q61928389 | T-cell repertoire and HIV infection |
| Q41452516 | T-cells in the pathogenesis of rheumatoid arthritis villains or accomplices? |
| Q41126119 | T-lymphocyte development and function in gene-targeted mutant mice |
| Q56953631 | TAP1-deficient mice select a CD8+ T cell repertoire that displays both diversity and peptide specificity |
| Q33937910 | TCF1 and beta-catenin regulate T cell development and function |
| Q28287007 | TGF beta 1 inhibits NF-kappa B/Rel activity inducing apoptosis of B cells: transcriptional activation of I kappa B alpha |
| Q36819179 | TSLP in epithelial cell and dendritic cell cross talk |
| Q42113339 | Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo |
| Q43625722 | Thapsigargin-induced apoptosis involves Cabin1-MEF2-mediated induction of Nur77. |
| Q41684972 | The Association of MHC with Autoimmune Diseases: Understanding the Pathogenesis of Autoimmune Diabetes |
| Q33675345 | The BALB/c mouse B-cell response to pigeon cytochrome c initiates as a heteroclitic response specific for the self antigen mouse cytochrome c. |
| Q74844549 | The Critical Role of LIGHT, a TNF Family Member, in T Cell Development |
| Q48011135 | The Fas Antigen and Fas-Mediated Apoptosis in B-Cell Differentiation |
| Q33989837 | The JNK and P38 MAP kinase signaling pathways in T cell-mediated immune responses |
| Q36401296 | The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes |
| Q34147585 | The Kinetics of Early T and B Cell Immune Recovery after Bone Marrow Transplantation in RAG-2-Deficient SCID Patients |
| Q47821082 | The Role of Interleukin-7 in Early T-Cell Development |
| Q77370064 | The Study of Self‐Tolerance Using Murine Haemoglobin as a Model Self Antigen |
| Q40511561 | The basis of autoimmunity: an overview |
| Q46479032 | The c-kit+ maturation pathway in mouse thymic T cell development: lineages and selection |
| Q35917268 | The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry |
| Q73756726 | The fate of the nuclear matrix-associated-region-binding protein SATB1 during apoptosis |
| Q40575824 | The genes influencing the susceptibility to IDDM in humans |
| Q41180651 | The lambda B cell repertoire of kappa-deficient mice. |
| Q35709655 | The many important facets of T-cell repertoire diversity |
| Q41692805 | The molecular basis of intractable diarrhoea of infancy |
| Q44029844 | The molecular mechanism in activation-induced cell death of an Ag-reactive B cell clone. |
| Q73467410 | The novel mechanism of peripheral tolerance |
| Q71877173 | The post-activation refractory phase: a mechanism to measure antigenic complexity and ensure self-tolerance among mature peripheral T lymphocytes |
| Q46268969 | The regulation and function of the Id proteins in lymphocyte development |
| Q41051482 | The resistance of activated T-cells from SLE patients to apoptosis induced by human thymic stromal cells |
| Q33753130 | The role of Fas-mediated apoptosis in thyroid autoimmune disease |
| Q36877356 | The role of integrins and coreceptors in refining thresholds for B-cell responses |
| Q51889610 | The self-antigen, thyroglobulin, induces antigen-experienced CD4+ T cells from healthy donors to proliferate and promote production of the regulatory cytokine, interleukin-10, by monocytes. |
| Q33942101 | The thymus and negative selection |
| Q36370712 | The transcriptional repressor Gfi1 affects development of early, uncommitted c-Kit+ T cell progenitors and CD4/CD8 lineage decision in the thymus |
| Q34150876 | The ubiquitously expressed Csk adaptor protein Cbp is dispensable for embryogenesis and T-cell development and function |
| Q35216936 | Thymic generation and regeneration |
| Q42943203 | Thymic selection and cell division |
| Q33816812 | Thymocyte apoptosis |
| Q35862276 | Thymocyte-targeted overexpression of xiap transgene disrupts T lymphoid apoptosis and maturation |
| Q42549632 | Thymosin alpha 1 antagonizes dexamethasone and CD3-induced apoptosis of CD4+ CD8+ thymocytes through the activation of cAMP and protein kinase C dependent second messenger pathways |
| Q73343719 | Thymosin alpha1 is a time and dose-dependent antagonist of dexamethasone-induced apoptosis of murine thymocytes in vitro |
| Q42625450 | Thymus‐homing dendritic cells in central tolerance |
| Q36184573 | Tissue-specific expression of the human prostate-specific antigen gene in transgenic mice: implications for tolerance and immunotherapy |
| Q42514204 | Tolerance and immunity to the inducible self antigen C-reactive protein in transgenic mice |
| Q42046571 | Transgenic expression of interleukin 7 restores T cell populations in nude mice |
| Q45771155 | Transgenic mice that express different forms of the influenza virus hemagglutinin as a neo-self-antigen |
| Q36369450 | Transplanted long-term cultured pre-BI cells expressing calpastatin are resistant to B cell receptor-induced apoptosis. |
| Q63965623 | Ultrastructural analysis of mouse thymocyte subpopulations |
| Q26827084 | Use of V(D)J recombination excision circles to identify T- and B-cell defects and to monitor the treatment in primary and acquired immunodeficiencies |
| Q74602325 | Valpha gene replacement in a TCRalpha knock-in mouse |
| Q36404575 | Virus-induced maturation and activation of autoreactive memory B cells |
| Q40434752 | Vβ Gene Repertoire in the Aging Mouse: A Developmental Perspective |
| Q36367471 | Whence the intestinal intraepithelial lymphocyte? |
| Q36647250 | Winner of the Theodore E. Woodward Award: c-Myb and the coordinate regulation of thymic genes |
| Q42480078 | ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells |
| Q46505598 | alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases |
| Q36366215 | bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice. |
| Q30448775 | c-Myb is essential for early T cell development |
| Q41954424 | p50-NF-kappaB complexes partially compensate for the absence of RelB: severely increased pathology in p50(-/-)relB(-/-) double-knockout mice |
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