Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders.

scientific article published on January 1995

Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/J.1460-2075.1995.TB06970.X
P932PMC publication ID398047
P698PubMed publication ID7530197

P2093author name stringHashimoto H
Suda T
Nagata S
Watanabe D
P2860cites workHuman Fas ligand: gene structure, chromosomal location and species specificityQ24310150
Isolation and characterization of the human chromosomal gene for polypeptide chain elongation factor-1 alphaQ24317250
Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicityQ24680778
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor familyQ28285445
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligandQ28513283
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosisQ29618601
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosisQ30080034
The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigenQ30988634
Overexpression of src family gene for tyrosine-kinase p59fyn in CD4-CD8- T cells of mice with a lymphoproliferative disorderQ34326573
Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative diseaseQ34602392
Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr miceQ36129002
Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicideQ36297378
Association of lpr gene with graft-vs.-host disease-like syndromeQ36350394
Differences defined by bone marrow transplantation suggest that lpr and gld are mutations of genes encoding an interacting pair of moleculesQ36353797
Autoimmune disease in mice due to integration of an endogenous retrovirus in an apoptosis geneQ36362052
The Fas protein is expressed at high levels on CD4+CD8+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lprQ36648389
Lethal effect of the anti-Fas antibody in miceQ36696599
Molecular cloning and tissue distribution of a receptor for pituitary adenylate cyclase-activating polypeptide.Q36772013
Tyrosine phosphorylation of a c-Src-like protein is increased in membranes of CD4- CD8- T lymphocytes from lpr/lpr miceQ36795299
Purification and characterization of the Fas-ligand that induces apoptosisQ38310834
Abnormal antigen receptor-initiated signal transduction in lpr T lymphocytesQ40388334
Positive selection of lymphocytesQ40807424
Negative selection of lymphocytesQ40807431
An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunityQ42941505
The autoimmune mouse MRL/Mp-lpr/lpr contains cells with spontaneous cytotoxic activity against target cells bearing self-determinantsQ43617051
Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunityQ46094710
Abnormal tyrosine phosphorylation on T-cell receptor in lymphoproliferative disordersQ46673762
Transcriptional Repression and Differential Splicing of Fas m-RNA by Early Transposon (ETn) Insertion in Autoimmune LPR MiceQ48129187
Evidence for early onset, polyclonal activation of T cell subsets in mice homozygous for lprQ52070302
Activation interferes with the APO-1 pathway in mature human T cells.Q54239983
Monoclonal antibody-mediated tumor regression by induction of apoptosis.Q55059937
Induction of Graft versus Host Disease in SCID Mice by MRL/lpr Cell TransferQ61883929
DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagementQ67531812
Autoimmunity and increased c-myb transcriptionQ70659793
Spontaneous and antibody directed cytotoxicity of double-negative T cells from autoimmune miceQ70719375
Fas-based lymphocyte-mediated cytotoxicity against syngeneic activated lymphocytes: a regulatory pathway?Q71617372
Functional distinctions between MRL-lpr and MRL-gld lymphocytes. Normal cells reverse the gld but not lpr immunoregulatory defectQ72273666
Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cellsQ72921121
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)12-18
P577publication date1995-01-01
P1433published inThe EMBO JournalQ1278554
P1476titleConstitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders
P478volume14

Reverse relations

cites work (P2860)
Q34600681'Activation-induced cell death': a special program able to preserve the homeostasis of the skin?
Q36368071A critical role for Fas ligand in the active suppression of systemic immune responses by ultraviolet radiation
Q36979743Autoantibody production in lpr/lpr gld/gld mice reflects accumulation of CD4+ effector cells that are resistant to regulatory T cell activity
Q64018952Bcl–2 protects from lethal hepatic apoptosis induced by an ant–Fas antibody in mice
Q33802379Bystander sensitization to activation-induced cell death as a mechanism of virus-induced immune suppression
Q41289470Clonal deletion of major histocompatibility complex class I‐restricted CD4+CD8+ thymocytes in vitro is independent of the CD95 (APO‐1/Fas) ligand
Q33500292Correction of Fas (CD95) deficiency by haploidentical bone marrow transplantation.
Q36366324Cytotoxic T cells deficient in both functional fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease
Q36339524Cytotoxic mechanisms employed by mouse T cells to destroy pancreatic β-cells.
Q35908961Death effectors of beta-cell apoptosis in type 1 diabetes
Q35716736Double negative regulatory T cells in transplantation and autoimmunity: recent progress and future directions
Q37711034Enhanced and accelerated lymphoproliferation in Fas-null mice
Q35092580Enhanced contact allergen- and UVB-induced keratinocyte apoptosis in the absence of CD95/Fas/Apo-1
Q35763713Enhanced lymphocyte longevity and absence of proliferation and lymphocyte apoptosis in Quilty effects of human heart allografts
Q40806057Expression of the functional soluble form of human fas ligand in activated lymphocytes.
Q35766053Fas activation increases neural progenitor cell survival
Q74623258Fas ligand (CD95 ligand) controls angiogenesis beneath the retina
Q53418059Fas ligand is highly expressed in acute leukemia and during the transformation of chronic myeloid leukemia to blast crisis.
Q71564585Fas receptor expression on B-lineage cells
Q57248069Fas-independent apoptosis in T-cell tumours induced by the CD2-myc transgene
Q28584047Fas/Apo [apoptosis]-1 and associated proteins in the differentiating cerebral cortex: induction of caspase-dependent cell death and activation of NF-kappaB
Q34769749FcRγ controls the fas-dependent regulatory function of lymphoproliferative double negative T cells
Q73320396Gender- and androgen-related influence on the expression of proto-oncogene and apoptotic factor mRNAs in lacrimal glands of autoimmune and non-autoimmune mice
Q42856573Identification of Fas-L-expressing apoptotic T lymphocytes in normal human peripheral blood : in vivo suicide
Q78644028Identification of a FasL-like molecule in leucocytes of the teleost fish gilthead seabream (Sparus aurata L.).
Q71708794Local Fas/APO-1 (CD95) ligand-mediated tumor cell killing in vivo
Q40068662Lymphocytic profiling in thyroid cancer provides clues for failure of tumor immunity.
Q36368261MRL-lpr/lpr mice exhibit a defect in maintaining developmental arrest and follicular exclusion of anti-double-stranded DNA B cells
Q73101472MRL/lpr CD4- CD8- and CD8+ T cells, respectively, mediate Fas-dependent and perforin cytotoxic pathways
Q36798787Mechanisms of beta cell death in diabetes: a minor role for CD95.
Q42093656Membrane-bound Fas ligand only is essential for Fas-induced apoptosis
Q34428954Onset of autoimmune lymphoproliferative syndrome (ALPS) in humans as a consequence of genetic defect accumulation
Q36706217Pathology and immunology of lupus glomerulonephritis: can we bridge the two?
Q37773421Programmed cell death of dendritic cells in immune regulation
Q41102922Role of Fas-mediated cell death in the regulation of immune responses
Q36399210T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis
Q59783966TNF-related ligands and their receptors
Q41515265The Fas pathway in apoptosis.
Q33434632The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis
Q37114374The dual functions of fas ligand in the regulation of peripheral CD8+ and CD4+ T cells
Q42944882The immune regulatory function of lymphoproliferative double negative T cells in vitro and in vivo.
Q34205697The many roles of FAS receptor signaling in the immune system
Q81094852The role of Fas ligand as an effector molecule in corneal graft rejection
Q79780583Treatment of autoimmune diseases in MRL/lpr mice by allogenic bone marrow transplantation plus adult thymus transplantation
Q34462324beta-Cell death during progression to diabetes

Search more.