| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1146/ANNUREV.IY.09.040191.001331 |
| P698 | PubMed publication ID | 1910678 |
| P2093 | author name string | Cohen PL | |
| Eisenberg RA | |||
| P304 | page(s) | 243-269 | |
| P577 | publication date | 1991-01-01 | |
| P1433 | published in | Annual Review of Immunology | Q567362 |
| P1476 | title | Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease | |
| P478 | volume | 9 |
| Q33882490 | 4SC-101, a novel small molecule dihydroorotate dehydrogenase inhibitor, suppresses systemic lupus erythematosus in MRL-(Fas)lpr mice |
| Q28210876 | 77 C/G mutation in the tyrosine phosphatase CD45 gene and autoimmune hepatitis: evidence for a genetic link |
| Q44410223 | A Function of Fas-Associated Death Domain Protein in Cell Cycle Progression Localized to a Single Amino Acid at Its C-Terminal Region |
| Q71806450 | A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma |
| Q53136156 | A novel IL-23p19/Ebi3 (IL-39) cytokine mediates inflammation in Lupus-like mice. |
| Q35604700 | A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease |
| Q44407054 | A novel role for sphingolipid intermediates in activation-induced cell death in T cells |
| Q73023757 | A pivotal role of cell-bound but not soluble CD4 molecules in full development of lupus-like manifestations in MRL-Fas(lprcg)/Fas(lprcg) mice |
| Q37949666 | A polygene network model for the complex pathological phenotypes of collagen disease |
| Q33654274 | A role for perforin in downregulating T-cell responses during chronic viral infection. |
| Q72416074 | A specific intercellular pathway of apoptotic cell death is defective in the mature peripheral T cells of autoimmune lpr and gld mice |
| Q72614796 | A unique syndrome of immunodeficiency and autoimmunity associated with absent T cell CD2 expression |
| Q36129002 | Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice |
| Q51067865 | Abnormal thymic maturation and lymphoproliferation in MRL-Fas lpr/lpr mice can be partially reversed by synthetic oligonucleotides: implications for systemic lupus erythematosus and autoimmune lymphoproliferative syndrome. |
| Q36426921 | Absence of CD59 exacerbates systemic autoimmunity in MRL/lpr mice |
| Q44973891 | Absence of citrulline-specific autoantibodies in animal models of autoimmunity |
| Q71524006 | Acquired immune deficiency syndrome caused by hyperimmunity |
| Q35848308 | Activated CD4+CD25+ T cells selectively kill B lymphocytes |
| Q33343068 | Activation and differentiation of autoreactive B-1 cells by interleukin 10 induce autoimmune hemolytic anemia in Fas-deficient antierythrocyte immunoglobulin transgenic mice |
| Q79361609 | Activation of autoreactive B cells by CpG dsDNA |
| Q71677084 | Acute rejection of vascular heart allografts by perforin-deficient mice |
| Q34606650 | Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies. |
| Q88500089 | Administration of activated lymphocyte-derived DNA accelerates and aggravates lupus nephritis in B6/lpr mice: a new approach to modify a lupus murine model |
| Q36032325 | Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus |
| Q35567264 | Alterations in the apoptotic machinery and their potential role in anticancer drug resistance |
| Q36934640 | Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor alpha (WSX-1). |
| Q44519899 | An abnormal signal transduction pathway in CD4−CD8− double-negative lymph node cells of MRLlpr/lpr mice |
| Q42941505 | An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunity |
| Q39326265 | An update on lupus animal models |
| Q37672419 | Analysis of gene profile, steady state proliferation and apoptosis of double-negative T cells in the periphery and gut epithelium provides new insights into the biological functions of the Fas pathway. |
| Q71800463 | Anatomy of autoantibody production: Dominant localization of antibody-producing cells to T cell zones in fas-deficient mice |
| Q27473541 | Animal models in ANCA-vasculitis |
| Q35646179 | Anti-Sm autoantibodies in systemic lupus erythematosus mice: a model system for disease-specific autoreactivity |
| Q77925969 | Antibody deposition in the stria vascularis of the MRL-Fas(lpr) mouse |
| Q35611385 | Antigen nonspecific effect of major histocompatibility complex haplotype on autoantibody levels in systemic lupus erythematosus-prone lpr mice |
| Q37175936 | Antigen presenting cells expressing Fas ligand down-modulate chronic inflammatory disease in Fas ligand-deficient mice |
| Q47401182 | Anti‑IL‑39 (IL‑23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus‑like mice |
| Q33836347 | Apoptosis and CD95 ligand in immune privileged sites |
| Q41493232 | Apoptosis and the B cell response to antigen |
| Q28304002 | Apoptosis by death factor |
| Q40396183 | Apoptosis defects analyzed in TcR transgenic and fas transgenic lpr mice |
| Q35091131 | Apoptosis in hematological disorders. |
| Q40551607 | Apoptosis in viral infections |
| Q37385429 | Apoptosis mediated by Fas but not tumor necrosis factor receptor 1 prevents chronic disease in mice infected with murine cytomegalovirus |
| Q43838631 | Apoptosis of CD4+ and CD8+ T cells during experimental infection with Mycobacterium avium is controlled by Fas/FasL and Bcl-2-sensitive pathways, respectively |
| Q45710561 | Apoptosis of infiltrating T cells in the central nervous system of mice infected with Theiler's murine encephalomyelitis virus. |
| Q37591407 | Apoptosis of nur77/N10-transgenic thymocytes involves the Fas/Fas ligand pathway |
| Q42132336 | Apoptosis regulators Fas and Bim synergistically control T-lymphocyte homeostatic proliferation |
| Q73985142 | Apoptosis with FasL+ cell infiltration in the periphery and thymus of corrected autoimmune mice |
| Q34404626 | Apoptosis, Part I: Biochemical assessment |
| Q71517555 | Apoptosis, nucleosomes, and nephritis in systemic lupus erythematosus |
| Q86081826 | Apoptosis-related Fas and FasL gene polymorphisms' associations with knee osteoarthritis |
| Q34015892 | Apoptosis: implications for inflammatory bowel disease |
| Q36905990 | Apoptotic Debris Accumulates on Hematopoietic Cells and Promotes Disease in Murine and Human Systemic Lupus Erythematosus |
| Q36581453 | Apoptotic cell death and lupus |
| Q71815100 | Apoptotic death of lymphocytes in murine acquired immunodeficiency syndrome: involvement of Fas-Fas ligand interaction |
| Q59276618 | Apoptotic responses common to cancer and inflammation |
| Q67546044 | Attenuation of autoimmune disease and lymphocyte accumulation in MRL/lpr mice by treatment with anti-V beta 8 antibodies |
| Q47901611 | Augmented levels of macrophage and Th1 cell-related cytokine mRNA in submandibular glands of MRL/lpr mice with autoimmune sialoadenitis. |
| Q40829522 | Autoantigen Ro52 directly interacts with human IgG heavy chain in vivo in mammalian cells |
| Q41098064 | Autoantigen-induced deletion of peripheral self-reactive T cells |
| Q36363024 | Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes |
| Q36362052 | Autoimmune disease in mice due to integration of an endogenous retrovirus in an apoptosis gene |
| Q40393793 | Autoimmune disease. a problem of defective apoptosis |
| Q72921121 | Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells |
| Q34114550 | Autoimmune lymphoproliferative syndrome. A human disorder of abnormal lymphocyte survival |
| Q33885931 | Autoimmunity as a consequence of retrovirus-mediated expression of C-FLIP in lymphocytes |
| Q36632364 | Autoimmunity: twenty years in the Fas lane |
| Q36799302 | Autophagy is dispensable for B-cell development but essential for humoral autoimmune responses |
| Q42741742 | Autoreactive MZ and B-1 B-cell activation by Faslpr is coincident with an increased frequency of apoptotic lymphocytes and a defect in macrophage clearance |
| Q36851881 | Autoregulation of Th1-mediated inflammation by twist1. |
| Q50134139 | B cell lymphoma 2 (Bcl-2) residues essential for Bcl-2's apoptosis-inducing interaction with Nur77/Nor-1 orphan steroid receptors. |
| Q30426692 | B cell maturation antigen deficiency exacerbates lymphoproliferation and autoimmunity in murine lupus |
| Q36979948 | B cells drive lymphocyte activation and expansion in mice with the CD45 wedge mutation and Fas deficiency |
| Q45295655 | B cells regulate thymic CD8+T cell differentiation in lupus-prone mice. |
| Q34813171 | B lymphocytes: how they develop and function. |
| Q57598947 | Bacille Calmette Guérin and interleukin-12 down-modulate interleukin-4-producing CD4+ NK1+ T lymphocytes |
| Q40393908 | Bcl-2 and Fas, molecules which influence apoptosis. A possible role in systemic lupus erythematosus? |
| Q38735628 | Bcl-2 proteins in development, health, and disease of the hematopoietic system. |
| Q43279065 | Beta(2) integrin deficiency yields unconventional double-negative T cells distinct from mature classical natural killer T cells in mice |
| Q35737865 | Bim and Bmf in tissue homeostasis and malignant disease |
| Q35145645 | Biology of FasL. |
| Q45113910 | Biology of the interleukin-2 receptor |
| Q39155259 | Bone marrow-derived mesenchymal stem cells inhibit T follicular helper cell in lupus-prone mice |
| Q41363502 | Bortezomib treatment induces a higher mortality rate in lupus model mice with a higher disease activity. |
| Q89236084 | Both perforin and FasL are required for optimal CD8 T cell control of autoreactive B cells and autoantibody production in parent-into-F1 lupus mice |
| Q36364520 | Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus |
| Q40193479 | C1q deficiency promotes the production of transgenic-derived IgM and IgG3 autoantibodies in anti-DNA knock-in transgenic mice |
| Q57956197 | CD 95-independent mechanisms of IL-2 deprivation-induced apoptosis in activated human lymphocytes |
| Q36536913 | CD1d deficiency exacerbates inflammatory dermatitis in MRL-lpr/lpr mice |
| Q28274504 | CD27-CD70 interaction: unravelling its implication in normal and neoplastic B-cell growth |
| Q62590575 | CD4 engagement induces Fas antigen-dependent apoptosis of T cellsin vivo |
| Q36403153 | CD4-CD8- T cells control intracellular bacterial infections both in vitro and in vivo |
| Q36229478 | CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance |
| Q34232649 | CD45: new jobs for an old acquaintance |
| Q36166909 | CD47 deficiency ameliorates autoimmune nephritis in Fas(lpr) mice by suppressing IgG autoantibody production |
| Q40386272 | CD5 B cells, a fetal B cell lineage |
| Q35769467 | CD8+ effector cells |
| Q45971909 | CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells |
| Q40375390 | CD95 and the MRL-lpr Mouse Model. |
| Q39656970 | CD95 is a key mediator of invasion and accelerated outgrowth of mouse colorectal liver metastases following radiofrequency ablation |
| Q41964046 | CD95 ligand (CD95L) in normal human lymphoid tissues: a subset of plasma cells are prominent producers of CD95L. |
| Q57462077 | CDR3 regions in the preimmune VH B cell repertoire of lpr mice |
| Q37034711 | CTL-promoting effects of CD40 stimulation outweigh B cell-stimulatory effects resulting in B cell elimination and disease improvement in a murine model of lupus |
| Q56906450 | CTLA4IgG gene delivery prevents autoantibody production and lupus nephritis in MRL/lpr mice |
| Q40846193 | CXCR5 is critically involved in progression of lupus through regulation of B cell and double-negative T cell trafficking |
| Q36252570 | Calcium/calmodulin-dependent protein kinase IV suppresses IL-2 production and regulatory T cell activity in lupus |
| Q33819040 | Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation |
| Q36403055 | Caspase-8 deficiency in T cells leads to a lethal lymphoinfiltrative immune disorder |
| Q35406486 | Caspase-8 inactivation in T cells increases necroptosis and suppresses autoimmunity in Bim-/- mice |
| Q36430147 | Caspases at the crossroads of immune-cell life and death |
| Q28300792 | Causes and consequences of the autoimmune lymphoproliferative syndrome |
| Q42728732 | Cell cycle arrest caused by MEK/ERK signaling is a mechanism for suppressing growth of antigen-hyperstimulated effector T cells |
| Q35269870 | Cell death in disease: from 2010 onwards |
| Q40872590 | Cell death/apoptosis: normal, chemically induced, and teratogenic effect |
| Q40379090 | Cell-mediated cytotoxicity in perforin-less mice |
| Q41231888 | Cellular interactions in the lpr and gld models of systemic autoimmunity |
| Q48570326 | Cerebral leucocyte infiltration in lupus-prone MRL/MpJ-fas lpr mice--roles of intercellular adhesion molecule-1 and P-selectin. |
| Q73643420 | Characterization of C5aR expression on murine myeloid and lymphoid cells by the use of a novel monoclonal antibody |
| Q72011159 | Characterization of autoimmune thyroiditis in MRL-lpr/lpr mice |
| Q80163940 | Characterization of the ETnII-alpha endogenous retroviral element in the BALB/cJ Zhx2 ( Afr1 ) allele |
| Q90373607 | Chronic Inflammation Promotes Skin Carcinogenesis in Cancer-Prone Discoid Lupus Erythematosus |
| Q59062762 | Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages |
| Q34441762 | Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation |
| Q36380452 | Clinical and serologic manifestations of autoimmune disease in MRL-lpr/lpr mice lacking nitric oxide synthase type 2. |
| Q41737519 | Clinical effects of mutations to CD95 (Fas): relevance to autoimmunity? |
| Q44778826 | Clonal analysis of peripheral T cell precursors in lpr mice |
| Q41289470 | Clonal deletion of major histocompatibility complex class I‐restricted CD4+CD8+ thymocytes in vitro is independent of the CD95 (APO‐1/Fas) ligand |
| Q74582446 | Combination of molecular mimicry and aberrant autoantigen expression is important for development of anti-Fas ligand autoantibodies in patients with systemic lupus erythematosus |
| Q34534879 | Complement factor H deficiency accelerates development of lupus nephritis |
| Q51021948 | Concomitant Disruption of CD4 and CD8 Genes Facilitates the Development of Double Negative αβ TCR+ Peripheral T Cells That Respond Robustly to Staphylococcal Superantigen. |
| Q41872230 | Conditional Fas-associated death domain protein (FADD): GFP knockout mice reveal FADD is dispensable in thymic development but essential in peripheral T cell homeostasis |
| Q36168991 | Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner. |
| Q33912061 | Conditional up-regulation of MHC class I in skeletal muscle leads to self-sustaining autoimmune myositis and myositis-specific autoantibodies |
| Q40805330 | Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders. |
| Q33654218 | Constitutive expression of murine c-FLIPR causes autoimmunity in aged mice |
| Q47593380 | Contribution of alphabeta and gammadelta T cells to the generation of primary immunoglobulin G-driven autoimmune response in immunoglobulin- mu-deficient/lpr mice |
| Q38170793 | Contributions of B cells to lupus pathogenesis |
| Q71824439 | Controlling programmed cell death with a cyclophilin-cyclosporin-based chemical inducer of dimerization |
| Q36361165 | Conventional B cells, not B-1 cells, are responsible for producing autoantibodies in lpr mice |
| Q35108481 | Correction of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal Fas apoptosis gene in the T cells of transgenic MRL-lpr/lpr mice |
| Q35909505 | CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease. |
| Q36377368 | Cross-linking of Fas by antibodies to a peculiar domain of gp120 V3 loop can enhance T cell apoptosis in HIV-1-infected patients |
| Q37778643 | Cutaneous lupus erythematosus: recent lessons from animal models |
| Q42942508 | Cytotoxicity of fresh NK1.1+ T cell receptor alpha/beta+ thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the target |
| Q36310860 | Daxx plays a novel role in T cell survival but is dispensable in Fas-induced apoptosis |
| Q28200822 | Death receptor Fas and autoimmune disease: from the original generation to therapeutic application of agonistic anti-Fas monoclonal antibody |
| Q35176421 | Death receptor signaling and autoimmunity |
| Q36290306 | Death receptors and caspases: role in lymphocyte proliferation, cell death, and autoimmunity |
| Q35691607 | Decay-accelerating factor ameliorates systemic autoimmune disease in MRL/lpr mice via both complement-dependent and -independent mechanisms |
| Q36132667 | Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice. |
| Q35547588 | Defective in vitro IL-2 production in lupus is an early but secondary event paralleling disease activity: evidence from the murine parent-into-F1 model supports staging of IL-2 defects in human lupus |
| Q36231826 | Defective maintenance of T cell tolerance to a superantigen in MRL-lpr/lpr mice |
| Q44541039 | Defects in the regulation of B cell apoptosis are required for the production of citrullinated peptide autoantibodies in mice |
| Q52589114 | Deficiency in EBV-induced gene 3 (EBI3) in MRL/lpr mice results in pathological alteration of autoimmune glomerulonephritis and sialadenitis. |
| Q35460597 | Deficiency of scavenger receptor BI leads to impaired lymphocyte homeostasis and autoimmune disorders in mice |
| Q73378621 | Delayed neurite regeneration and its improvement by nerve growth factor (NGF) in dorsal root ganglia from MRL-lpr/lpr mice in vitro |
| Q35789124 | Deletion of decay-accelerating factor (CD55) exacerbates autoimmune disease development in MRL/lpr mice |
| Q37395145 | Deletion of microRNA-155 reduces autoantibody responses and alleviates lupus-like disease in the Fas(lpr) mouse |
| Q72333309 | Development of grafted gld cells in athymic and euthymic recipients |
| Q28144319 | Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor |
| Q48060639 | Differences in V kappa gene utilization and VH CDR3 sequence among anti-DNA from C3H-lpr mice and lupus mice with nephritis |
| Q36237736 | Differentiation of rodent immune and hematopoietic system reactive lesions from neoplasias |
| Q30442845 | Distinct T cell receptor signaling requirements for perforin- or FasL-mediated cytotoxicity |
| Q81219854 | Do autoantigens define autoimmunity or vice versa? |
| Q35186959 | Double negative (DN) αβ T cells: misperception and overdue recognition |
| Q91646560 | Double negative T cells, a potential biomarker for systemic lupus erythematosus |
| Q74510647 | Double-negative (CD4-CD8-) TCRalphabeta+ cells in patients with systemic lupus erythematosus |
| Q52894083 | Double-negative BV8S3 T cells expanded in MRL lpr/lpr lymph nodes conserve TCRBJ gene usage of single-positive BV8S3 T cells. |
| Q38313878 | Double-negative T cells from MRL-lpr/lpr mice mediate cytolytic activity when triggered through adhesion molecules and constitutively express perforin gene. |
| Q52663141 | Drug delivery and epimorphic salamander-type mouse regeneration: A full parts and labor plan. |
| Q36278075 | Dual-reactive B cells are autoreactive and highly enriched in the plasmablast and memory B cell subsets of autoimmune mice |
| Q44919838 | Dysregulated Expression of Cellular Adhesion Molecules in Autoimmune‐prone Mice |
| Q97529670 | EGR2 is elevated and positively regulates inflammatory IFNγ production in lupus CD4+ T cells |
| Q36536967 | Effect of an exogenous trigger on the pathogenesis of lupus in (NZB x NZW)F1 mice |
| Q54254873 | Effect of mycobacterial infection in the lupus-prone MRL/lpr mice: enhancement of life span of autoimmune mice, amelioration of kidney disease and transient decrease in host resistance. |
| Q33811734 | Effects of anti-Fas antibodies on lymphocytes and other organs: preparation of original and new monoclonal antibodies and amelioration of systemic autoimmune disease |
| Q74551655 | Effects of dexamethasone on the expression of Fas molecules and apoptosis of lymphocytes in patients with systemic lupus erythematosus |
| Q42845326 | Effects of low-dose-gamma rays on the immune system of different animal models of disease |
| Q71942236 | Efficient Inhibition of Activation-induced Fas Ligand Up-regulation and T Cell Apoptosis by Retinoids Requires Occupancy of both Retinoid X Receptors and Retinoic Acid Receptors |
| Q39492463 | Elimination of autoreactive B cells in humanized SCID mouse model of SLE. |
| Q55077356 | Emerging Functions of Regulatory T Cells in Tissue Homeostasis. |
| Q40671712 | Endothelial cell overexpression of fas ligand attenuates ischemia-reperfusion injury in the heart |
| Q37711034 | Enhanced and accelerated lymphoproliferation in Fas-null mice |
| Q34564667 | Enhanced auto-antibody production and Mott cell formation in FcμR-deficient autoimmune mice. |
| Q41187911 | Enhanced tubular epithelial CD44 expression in MRL-lpr lupus nephritis |
| Q78257965 | Epistatic modifiers of autoimmunity in a murine model of lupus nephritis |
| Q33803417 | Establishment of monoclonal anti-retroviral gp70 autoantibodies from MRL/lpr lupus mice and induction of glomerular gp70 deposition and pathology by transfer into non-autoimmune mice. |
| Q24648556 | Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival |
| Q84860683 | Evaluation of apoptosis-related gene Fas (CD95) and FasL (CD178) polymorphisms in Iranian rheumatoid arthritis patients |
| Q71729343 | Evaluation of the BCL-2 gene locus as a susceptibility locus linked to the clinical expression of systemic lupus erythematosus (SLE) |
| Q45859807 | Evidence for aberrant regulation of MAP kinase signal transduction pathway in peripheral blood mononuclear cells in patients with active celiac disease |
| Q36399625 | Evidence for selective transformation of autoreactive immature plasma cells in mice deficient in Fasl |
| Q46863693 | Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor. |
| Q73882570 | Expression of Fas ligand mRNA in germinal centres of the human tonsil |
| Q36670145 | Expression of a Pim-1 transgene accelerates lymphoproliferation and inhibits apoptosis in lpr/lpr mice |
| Q42799698 | Expression of the B cell repertoire in lpr mice; abnormal expansion of a few VHJ558 germ-line genes |
| Q40806057 | Expression of the functional soluble form of human fas ligand in activated lymphocytes. |
| Q40686851 | Extrathymic differentiation of a T cell bearing invariant V alpha 14J alpha 281 TCR. |
| Q33711133 | FAS is highly expressed in the germinal center but is not required for regulation of the B-cell response to antigen |
| Q33782588 | FTY720: mechanisms of action and its effect on organ transplantation (review). |
| Q71577021 | Fas (CD95) expression on CD4+ T cells from HIV-infected patients increases with disease progression |
| Q33761193 | Fas (CD95)-dependent cell-mediated immunity to Listeria monocytogenes. |
| Q34538716 | Fas (CD95/APO-1) limits the expansion of T lymphocytes in an environment of limited T-cell antigen receptor/MHC contacts |
| Q36236704 | Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover |
| Q33860215 | Fas and Fas ligand in gut and liver |
| Q40398073 | Fas and Fas ligand: a death factor and its receptor. |
| Q36364854 | Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: inhibition of Fas ligand expression by retinoic acid and glucocorticoids |
| Q35326190 | Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity |
| Q37305254 | Fas expression on antigen-specific T cells has costimulatory, helper, and down-regulatory functions in vivo for cytotoxic T cell responses but not for T cell-dependent B cell responses |
| Q48377105 | Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire |
| Q77394164 | Fas ligand (FasL, CD95L, APO-1L) expression in murine mast cells |
| Q34334400 | Fas ligand deficiency impairs host inflammatory response against infection with the spirochete Borrelia burgdorferi |
| Q42942730 | Fas ligand mediates activation-induced cell death in human T lymphocytes |
| Q28115268 | Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease |
| Q39018355 | Fas ligation induces apoptosis of CD40-activated human B lymphocytes |
| Q28248826 | Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation |
| Q36314636 | Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis |
| Q71564585 | Fas receptor expression on B-lineage cells |
| Q41710749 | Fas- and perforin-independent mechanism of cytotoxic T lymphocyte |
| Q71617372 | Fas-based lymphocyte-mediated cytotoxicity against syngeneic activated lymphocytes: a regulatory pathway? |
| Q57248069 | Fas-independent apoptosis in T-cell tumours induced by the CD2-myc transgene |
| Q37174968 | Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis |
| Q33378507 | Fas-mediated apoptosis regulates the composition of peripheral alphabeta T cell repertoire by constitutively purging out double negative T cells |
| Q36238055 | Fas-positive T cells regulate the resolution of airway inflammation in a murine model of asthma |
| Q37541681 | Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction |
| Q62071806 | Fas/Fas ligand (FasL)-deregulated apoptosis and IL-6 insensitivity in highly malignant myeloma cells |
| Q40893570 | Fas/FasL, Bcl2 and Caspase-8 gene polymorphisms in Chinese patients with rheumatoid arthritis |
| Q45050335 | Fas/FasL-mediated apoptosis in perinatal murine lungs |
| Q52548809 | FasL deficiency enhances the development of tumors in p53+/- mice. |
| Q57338698 | Fascinating death factor |
| Q39681532 | Fn14 deficiency protects lupus-prone mice from histological lupus erythematosus-like skin inflammation induced by ultraviolet light |
| Q39084764 | Foxd3 suppresses interleukin-10 expression in B cells |
| Q72564555 | Frequent occurrence of in vivo clonal expansion of CD4- CD8- T cells bearing T cell receptor alpha beta chains in adult humans |
| Q43876842 | Functional Analyses of lprGene in MRL/Mp-lpr/lprMice. Role of Lymph Node StromalCells in lpr-Lymphadenopathy |
| Q58415191 | Functional Consequences of APO-1/Fas (CD95) Antigen Expression by Normal and Neoplastic Hematopoietic Cells |
| Q41187958 | Functional analysis of Fas signaling in vivo using synthetic inducers of dimerization |
| Q60532577 | Functional double-negative T cells in the periphery express T cell receptor Vβ gene products that cause deletion of single-positive T cells |
| Q28591401 | Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis |
| Q34167992 | Generation and maintenance of memory T cells |
| Q40433254 | Genetic Contributions to Lupus‐like Disease in (NZB×NZW)F1 Mice |
| Q36232118 | Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci |
| Q36321639 | Genetic analysis of a mammalian wound-healing trait |
| Q35661227 | Genetic basis of murine lupus. |
| Q71972615 | Genetic basis of systemic lupus erythematosus |
| Q34052010 | Genetic basis of the complex pathological manifestations of collagen disease: lessons from MRL/lpr and related mouse models |
| Q36923999 | Genetic contributions to the autoantibody profile in a rabbit model of Systemic Lupus Erythematosus (SLE). |
| Q36370883 | Genetic dissection of SLE: SLE1 and FAS impact alternate pathways leading to lymphoproliferative autoimmunity |
| Q33853007 | Genetic dissection of lupus pathogenesis: a recipe for nephrophilic autoantibodies |
| Q33814991 | Genetic dissection of systemic lupus erythematosus |
| Q79333229 | Genetic interactions between susceptibility loci reveal epistatic pathogenic networks in murine lupus |
| Q56922011 | Genetic susceptibility to PolyI:C-induced IFNα/β-dependent accelerated disease in lupus-prone mice |
| Q78157765 | Glomerular overexpression and increased tyrosine phosphorylation of focal adhesion kinase p125FAK in lupus-prone MRL/MP-lpr/lpr mice |
| Q36364361 | Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I. |
| Q35016981 | HDAC inhibition in lupus models |
| Q36219516 | Harnessing programmed cell death as a therapeutic strategy in rheumatic diseases |
| Q35070659 | Hematopoietic Fas deficiency does not affect experimental atherosclerotic lesion formation despite inducing a proatherogenic state |
| Q36375688 | High pathogenic potential of low-affinity autoantibodies in experimental autoimmune hemolytic anemia. |
| Q71930222 | Homeostatic regulation of CD8+ T cells after antigen challenge in the absence of Fas (CD95) |
| Q38062548 | Hormones and AID: balancing immunity and autoimmunity |
| Q35764934 | Host modifier genes affect mouse autoimmunity induced by the lpr gene |
| Q24633207 | How I treat autoimmune lymphoproliferative syndrome |
| Q83024649 | How host defense is encoded in the mammalian genome |
| Q38554722 | Human autoimmune diseases: a comprehensive update |
| Q33338363 | Hyperactivity in a mouse model of the antiphospholipid syndrome |
| Q48160460 | Hypothalamic beta-endorphin concentrations are decreased in animals models of autoimmune disease |
| Q37838092 | IL-17-producing T cells in lupus nephritis |
| Q33715791 | IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease |
| Q36745302 | IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice |
| Q35142708 | IRF4 deficiency abrogates lupus nephritis despite enhancing systemic cytokine production |
| Q35070231 | IRF5 deficiency ameliorates lupus but promotes atherosclerosis and metabolic dysfunction in a mouse model of lupus-associated atherosclerosis |
| Q81733014 | Identification of T-cell epitopes on U1A protein in MRL/lpr mice: double-negative T cells are the major responsive cells |
| Q77924186 | Identification of candidate genes for Sjögren's syndrome using MRL/lpr mouse model of Sjögren's syndrome and cDNA microarray analysis |
| Q58826931 | IgG glycosylation in autoimmune-prone strains of mice |
| Q67792108 | Imbalanced cytokine production by macrophages from autoimmune-prone mice |
| Q37957001 | Immune functioning in non lymphoid organs: the liver |
| Q30679878 | Immunocytochemical detection of leukocyte-associated and apoptosis-related antigen expression in childhood brain tumors |
| Q44087976 | Immunoglobulin and autoantibody responses in MRL/lpr mice treated with 'toxic oils'. |
| Q81239549 | Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: roles of IL-2 versus IL-15 |
| Q22008837 | Immunophilins, Refsum disease, and lupus nephritis: the peroxisomal enzyme phytanoyl-COA alpha-hydroxylase is a new FKBP-associated protein |
| Q41154690 | Impact of loss of NF-κB1, NF-κB2 or c-REL on SLE-like autoimmune disease and lymphadenopathy in Fas(lpr/lpr) mutant mice |
| Q36371686 | Impaired T cell death and lupus-like autoimmunity in T cell-specific adapter protein-deficient mice |
| Q36399434 | Impaired clearance of apoptotic cells promotes synergy between atherogenesis and autoimmune disease |
| Q36789696 | In vitro detection of apoptotic stimuli by use of the HL-60 myeloid leukemic cell line. |
| Q41780931 | Increased B cell deletion and significantly reduced auto-antibody titre due to premature expression of human complement receptor 2 (CR2, CD21). |
| Q31002573 | Increased ICAM-1 and VCAM-1 expression in the brains of autoimmune mice |
| Q52519969 | Increased activation and altered ratio of interferon-gamma: interleukin-4 secreting cells in MRL-lpr/lpr mice. |
| Q60156866 | Increased inducible apoptosis in CD4+ T lymphocytes during polymicrobial sepsis is mediated by Fas ligand and not endotoxin |
| Q40694417 | Increased interleukin-6 (IL-6) production in a young child with clinical and pathologic features of multicentric Castleman's disease |
| Q79696856 | Increased proliferation of CD8+ T cells in SAP-deficient mice is associated with impaired activation-induced cell death |
| Q26827445 | Increased serum IL-10 in lupus patients promotes apoptosis of T cell subsets via the caspase 8 pathway initiated by Fas signaling |
| Q24293504 | Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death |
| Q34146806 | Inducible resistance to Fas-mediated apoptosis in B cells |
| Q42119270 | Induction of rapid T cell death and phagocytic activity by Fas-deficient lpr macrophages |
| Q28247635 | Inflammation and Its Correlates in Regenerative Wound Healing: An Alternate Perspective |
| Q72590688 | Influence of the lpr environment on the lymph node cell phenotypes in C57BL/6 nubg and nulpr chimeras |
| Q22010404 | Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II |
| Q52230956 | Inhibition of abnormal T cell development and autoimmunity in gld mice by transgenic T cell receptor beta chain. |
| Q54661197 | Inhibition of osteoporosis in autoimmune disease prone MRL/Mpj-Fas(lpr) mice by N-3 fatty acids. |
| Q39594251 | Inhibition of tumor necrosis factor alpha by an adenovirus-encoded soluble fusion protein extends transgene expression in the liver and lung |
| Q54113549 | Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development. |
| Q41123935 | Inner ear DNA receptors in MRL/lpr autoimmune mice: potential 30 and 70 kDa link between autoimmune disease and hearing loss. |
| Q90040247 | Insights into Thymus Development and Viral Thymic Infections |
| Q47966533 | Insulin growth factor-I inhibits apoptosis in hematopoietic progenitor cells. Implications in thymic aging |
| Q43538775 | Interferon regulatory factor 5 is critical for the development of lupus in MRL/lpr mice. |
| Q38758838 | Interleukin (IL)-39 [IL-23p19/Epstein-Barr virus-induced 3 (Ebi3)] induces differentiation/expansion of neutrophils in lupus-prone mice |
| Q72564621 | Interleukin-1 dysregulation is an intrinsic defect in macrophages from MRL autoimmune-prone mice |
| Q48959151 | Involvement of Fas antigen in ovarian follicular atresia and luteolysis |
| Q28586379 | Involvement of a tissue-specific autoantibody in skin disorders of murine systemic lupus erythematosus and autoinflammatory diseases |
| Q45751487 | Involvement of autoimmunity against type II collagen in the development of arthritis in mice transgenic for the human T cell leukemia virus type I tax gene |
| Q40701449 | Involvement of the peripheral benzodiazepine receptor in the development of rheumatoid arthritis in Mrl/lpr mice |
| Q34516568 | Isotype-dependent pathogenicity of autoantibodies: analysis in experimental autoimmune hemolytic anemia |
| Q52197567 | Kinetics of Fas-induced apoptosis in thymic organ culture. |
| Q40894893 | Labor-associated changes in Fas ligand expression and function in human placenta |
| Q36368991 | Lack of coreceptor allows survival of chronically stimulated double-negative alpha/beta T cells: implications for autoimmunity |
| Q33920964 | Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus |
| Q72221552 | Lack of transfer of lpr-type abnormalities (lymphoproliferation or lymphoid aplasia) in double congenic nude beige mice engrafted with lpr haematopoietic cells |
| Q34109058 | Lessons from animal models of vasculitis |
| Q34051998 | Lessons from the NZM2410 model and related strains |
| Q22254187 | Limitin: An interferon-like cytokine that preferentially influences B-lymphocyte precursors |
| Q36086411 | Liver immunobiology |
| Q38838638 | Liver receptor homolog-1 (NR5a2) regulates CD95/Fas ligand transcription and associated T-cell effector functions. |
| Q41195420 | Looking beneath the surface: the cell death pathway of Fas/APO-1 (CD95). |
| Q91595484 | Low-dose 17α-ethinyl estradiol (EE) exposure exacerbates lupus renal disease and modulates immune responses to TLR7/9 agonists in genetically autoimmune-prone mice |
| Q55061885 | Lpr-induced systemic autoimmunity is unaffected by mast cell deficiency. |
| Q37364712 | Lung lymphocyte elimination by apoptosis in the murine response to intratracheal particulate antigen |
| Q35763464 | Lymphocyte apoptosis during early phase of Listeria infection in mice |
| Q42789442 | Lymphocyte apoptosis during the silencing of the immune response to acute viral infections in normal, lpr, and Bcl-2-transgenic mice |
| Q30080034 | Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis |
| Q64060940 | MMP-9/Gelatinase B Degrades Immune Complexes in Systemic Lupus Erythematosus |
| Q73101472 | MRL/lpr CD4- CD8- and CD8+ T cells, respectively, mediate Fas-dependent and perforin cytotoxic pathways |
| Q34516535 | Maintenance and loss of self-tolerance in B cells |
| Q50738767 | Manipulation of B-cell responses with histone deacetylase inhibitors. |
| Q35045888 | Many paths lead to lupus. |
| Q71548635 | Marked depletion at the late pro-B cell stage in the bone marrow of lpr mice correlates with the development of lymphadenopathy but not autoimmunity |
| Q41404960 | Massive upregulation of the Fas ligand in lpr and gld mice: implications for Fas regulation and the graft-versus-host disease-like wasting syndrome |
| Q35758450 | Mdm2 promotes systemic lupus erythematosus and lupus nephritis |
| Q44096997 | Mechanisms behind flare of renal lupus during murine pregnancy |
| Q73663942 | Mechanisms of autoimmunity |
| Q36798787 | Mechanisms of beta cell death in diabetes: a minor role for CD95. |
| Q36069516 | Mechanisms of gastric mucosal cell loss in autoimmune gastritis |
| Q28592588 | Mechanisms of necroptosis in T cells |
| Q34170767 | Mechanisms of self-tolerance and autoimmunity: from whole-animal phenotypes to molecular pathways. |
| Q40868802 | Mechanisms of systemic autoimmunity in murine models of SLE. |
| Q40928703 | Mechanisms of the pathogenic autoimmune response in lupus: prospects for specific immunotherapy |
| Q41312354 | Mechanisms of tolerance to self |
| Q26852802 | Membrane trafficking of death receptors: implications on signalling |
| Q48275307 | Mice lacking functional CD95-ligand display reduced proliferation of the intestinal epithelium without gross homeostatic alterations. |
| Q28216909 | Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus |
| Q71959132 | Modulation of B-cell abnormalities in lupus-prone (NZB x NZW)F1 mice by normal bone marrow-derived B-lineage cells |
| Q36419531 | Modulation of Lupus Phenotype by Adiponectin Deficiency in Autoimmune Mouse Models |
| Q41098577 | Modulation of resistance to anti-APO-1-induced apoptosis in osteosarcoma cells by cytokines |
| Q28210886 | Molecular Cloning, Genomic Structure, and Expression Analysis of MUC20, a Novel Mucin Protein, Up-regulated in Injured Kidney |
| Q32067958 | Molecular cloning of metaphase chromosome protein 1 (MCP1), a novel human autoantigen that associates with condensed chromosomes during mitosis. |
| Q37973770 | Monogenic autoimmunity |
| Q42047613 | Multiple T cell subsets control Francisella tularensis LVS intracellular growth without stimulation through macrophage interferon gamma receptors |
| Q52206363 | Murine lupus in MRL/lpr mice lacking CD4 or CD8 T cells. |
| Q36231469 | Murine thymic CD4+ T cell subsets: a subset (Thy0) that secretes diverse cytokines and overexpresses the V beta 8 T cell receptor gene family |
| Q36991699 | NADPH oxidase inhibits the pathogenesis of systemic lupus erythematosus. |
| Q28586033 | NFAT/Fas signaling mediates the neuronal apoptosis and motor side effects of GSK-3 inhibition in a mouse model of lithium therapy |
| Q33547794 | NK cells and apoptosis. |
| Q33908254 | Naja naja atra Venom Protects against Manifestations of Systemic Lupus Erythematosus in MRL/lpr Mice |
| Q37074021 | Naturally occurring mitochondrial DNA heteroplasmy in the MRL mouse |
| Q34936432 | Neuronal apoptosis and motor deficits in mice with genetic inhibition of GSK-3 are Fas-dependent |
| Q34941147 | Nitric oxide as an inflammatory mediator in autoimmune MRL-lpr/lpr mice |
| Q34242689 | Nitric oxide synthase 2 and cyclooxygenase 2 interactions in inflammation |
| Q74069414 | Nitrosylation of blood hemoglobin and renal nonheme proteins in autoimmune MRL-lpr/lpr mice |
| Q34506140 | Normal regulatory alpha/beta T cells effectively eliminate abnormally activated T cells lacking the interleukin 2 receptor beta in vivo |
| Q28396263 | Nuclear Factor Erythroid 2-related Factor 2 Deficiency Exacerbates Lupus Nephritis in B6/lpr mice by Regulating Th17 Cell Function |
| Q36361685 | Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus |
| Q30417375 | Optimized protocol for the isolation of spleen-resident murine neutrophils |
| Q53640412 | Oral vaccination against Helicobacter pylori infection is not effective in mice with Fas ligand deficiency. |
| Q37549558 | Osteopontin Bridging Innate and Adaptive Immunity in Autoimmune Diseases. |
| Q42284538 | Overexpression of Epstein-Barr virus-induced gene 3 protein (EBI3) in MRL/lpr mice suppresses their lupus nephritis by activating regulatory T cells |
| Q37691426 | Overexpression of Mcl-1 exacerbates lymphocyte accumulation and autoimmune kidney disease in lpr mice. |
| Q73807451 | PD-1: an inhibitory immunoreceptor involved in peripheral tolerance |
| Q36364838 | Pancreatic islet beta cells drive T cell-immune responses in the nonobese diabetic mouse model. |
| Q34700085 | Parasites alter the pathological phenotype of lupus nephritis |
| Q35060808 | Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice |
| Q37371294 | Perforin/granzyme-dependent and independent mechanisms are both important for the development of graft-versus-host disease after murine bone marrow transplantation |
| Q36370130 | Perinatal blockade of b7-1 and b7-2 inhibits clonal deletion of highly pathogenic autoreactive T cells |
| Q34193042 | Peripheral T-cell tolerance defined through transgenic mouse studies |
| Q36380653 | Peripheral selection of T cell repertoires: the role of continuous thymus output |
| Q87152428 | Peroxisome proliferator-activated receptor gamma agonists in the prevention and treatment of murine systemic lupus erythematosus |
| Q35949095 | Pharmacokinetics of Py-Im polyamides depend on architecture: cyclic versus linear |
| Q29620319 | Points of control in inflammation |
| Q36107352 | Polymorphism of murine Fas ligand that affects the biological activity |
| Q47849301 | Posttranslational protein modifications, apoptosis, and the bypass of tolerance to autoantigens |
| Q34278189 | Prevention of immune nephritis by the small molecular weight immunomodulator iguratimod in MRL/lpr mice |
| Q35981808 | Programmed Death 1 (PD-1) is involved in the development of proliferative diabetic retinopathy by mediating activation-induced apoptosis. |
| Q46163524 | Programmed cell death (apoptosis) in cord blood lymphocytes |
| Q52530889 | Proliferation of CD3+ B220- single-positive normal T cells was suppressed in B-cell-deficient lpr mice. |
| Q24806392 | Prostaglandin F2alpha- and FAS-activating antibody-induced regression of the corpus luteum involves caspase-8 and is defective in caspase-3 deficient mice |
| Q35928288 | Protection from autoimmune diabetes and T-cell lymphoproliferation induced by FasL mutation are differentially regulated and can be uncoupled pharmacologically |
| Q37950926 | RIP1-mediated regulation of lymphocyte survival and death responses |
| Q90456884 | RNAi Silencing of HIF-1α Ameliorates Lupus Development in MRL/lpr Mice |
| Q36158038 | Radiation and stress-induced apoptosis: a role for Fas/Fas ligand interactions |
| Q42485739 | Radiation-induced expression of functional Fas ligand in EBV-positive human nasopharyngeal carcinoma cells. |
| Q40890162 | Rapid B cell apoptosis induced by antigen receptor ligation does not require Fas (CD95/APO-1), the adaptor protein FADD/MORT1 or CrmA-sensitive caspases but is defective in both MRL-+/+ and MRL-lpr/lpr mice |
| Q34170819 | Receptor-mediated apoptosis in T lymphocytes |
| Q41737516 | Receptors and ligands that mediate activation-induced death of T cells |
| Q73444728 | Recognition of DNA by VH and Fv domains of an IgG anti-poly(dC) antibody with a singly mutated VH domain |
| Q72463299 | Reduced galactosyltransferase mRNA levels are associated with the agalactosyl IgG found in arthritis-prone MRL-lpr/lpr strain mice |
| Q28592335 | Regulation of Fas ligand expression and cell death by apoptosis-linked gene 4 |
| Q40691063 | Regulation of T cell-dependent autoantibody production by a gammadelta T cell line derived from lupus-prone mice |
| Q40400964 | Regulation of apoptosis in immune cells |
| Q61628138 | Regulation of autoimmunity by proinflammatory cytokines |
| Q36419022 | Regulatory T cells in lupus |
| Q34325897 | Regulatory role of CD4+ T cells during the development of contact hypersensitivity responses |
| Q35083681 | Relationship of acute lung inflammatory injury to Fas/FasL system |
| Q36186103 | Reno-protective effect and mechanism study of Huang Lian Jie Du Decoction on lupus nephritis MRL/lpr mice |
| Q35791280 | Requirement of myeloid cell-specific Fas expression for prevention of systemic autoimmunity in mice |
| Q32045053 | Rheumatoid arthritis synovial macrophages express the Fas-associated death domain-like interleukin-1beta-converting enzyme-inhibitory protein and are refractory to Fas-mediated apoptosis |
| Q37801738 | Role for toll-like receptors in autoimmune disease: The example of systemic lupus erythematosus |
| Q53912452 | Role of Complement-Binding CD21/CD19/CD81 in Enhancing Human B Cell Protection from Fas-Mediated Apoptosis |
| Q33850700 | Role of Fas--FasL interactions in the pathogenesis and regulation of autoimmune demyelinating disease |
| Q36065912 | Role of MHC-linked susceptibility genes in the pathogenesis of human and murine lupus |
| Q33966313 | Role of TNF in lymphocyte-mediated cytotoxicity |
| Q40932742 | Role of apoptosis in HIV disease pathogenesis |
| Q80562640 | Role of endogenous 4-1BB in the development of systemic lupus erythematosus |
| Q37365961 | Roles of interferon-gamma and interleukin-4 in murine lupus |
| Q47992177 | SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development |
| Q41399533 | Searching for genes involved in the pathogenesis of primary immunodeficiency diseases: lessons from mouse knockouts |
| Q42942821 | Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody |
| Q40373293 | Self-tolerance checkpoints in B lymphocyte development |
| Q41070378 | Separate domains of the human fas ligand dictate self-association and receptor binding |
| Q91740956 | Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL-Faslpr Mice |
| Q35879514 | Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus. |
| Q40376398 | Signaling Lymphocytic Activation Molecule Family Member 7 Engagement Restores Defective Effector CD8+ T Cell Function in Systemic Lupus Erythematosus. |
| Q29616428 | Signalling pathways of the TNF superfamily: a double-edged sword |
| Q74556952 | Significant role of Fas ligand-binding but defective Fas receptor (CD95) in lymph node hyperplasia composed of abnormal double-negative T cells |
| Q37311012 | Silica, apoptosis, and autoimmunity |
| Q51743751 | Skin disease is prevented but nephritis is accelerated by multiple pregnancies in autoimmune MRL/LPR mice. |
| Q90266667 | Soluble FAS ligand is not required for pancreatic islet inflammation or beta-cell destruction in non-obese diabetic mice |
| Q42060857 | Soluble FasR ligand-binding domain: high-yield production of active fusion and non-fusion recombinant proteins using the baculovirus/insect cell system |
| Q46404853 | Soy isoflavones supplementation alleviates disease severity in autoimmune-prone MRL-lpr/lpr mice. |
| Q36400965 | Spontaneous development of plasmacytoid tumors in mice with defective Fas-Fas ligand interactions |
| Q42942667 | Spontaneous elaboration of transforming growth factor beta suppresses host defense against bacterial infection in autoimmune MRL/lpr mice |
| Q47136733 | Stabilized β-Catenin Ameliorates ALPS-Like Symptoms of B6/lpr Mice |
| Q35691052 | Stage-dependent reactivity of thymocytes to self-peptide--MHC complexes |
| Q41613826 | Stearoyl-CoA desaturase gene expression in lymphocytes |
| Q46595056 | Structural requirements for signal-induced target binding of FADD determined by functional reconstitution of FADD deficiency |
| Q32081421 | Structure-activity relationship of the p55 TNF receptor death domain and its lymphoproliferation mutants |
| Q35176317 | Studies of murine systemic autoimmunity |
| Q39207717 | Sugar-free, glycine-stabilized intravenous immunoglobulin prevents skin but not renal disease in the MRL/lpr mouse model of systemic lupus |
| Q78951897 | Suppression of antibody production by TNF-related apoptosis-inducing ligand (TRAIL) |
| Q71046919 | Systemic lupus erythematosus |
| Q36958449 | T cell receptor-induced activation and apoptosis in cycling human T cells occur throughout the cell cycle |
| Q40787117 | T cell repertoire and autoimmune diseases |
| Q35940897 | T cell-specific FADD-deficient mice: FADD is required for early T cell development |
| Q36399210 | T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis |
| Q41472266 | T cells of staphylococcal enterotoxin B-tolerized autoimmune MRL-lpr/lpr mice require co-stimulation through the B7-CD28/CTLA-4 pathway for activation and can be reanergized in vivo by stimulation of the T cell receptor in the absence of this co-sti |
| Q37783748 | T follicular helper cells during immunity and tolerance. |
| Q34702070 | T follicular helper cells mediate expansion of regulatory B cells via IL-21 in Lupus-prone MRL/lpr mice |
| Q33957697 | T-cell receptor crossreactivity and autoimmune disease |
| Q34093298 | T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency |
| Q34716347 | T-cell signalling and autoimmunity: molecular mechanisms of disease |
| Q41942006 | T-cell tolerance: central and peripheral |
| Q33954374 | T. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosis |
| Q22254041 | TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease |
| Q74171887 | TCR antigen-induced cell death occurs from a late G1 phase cell cycle check point |
| Q24746223 | TDAG51 is not essential for Fas/CD95 regulation and apoptosis in vivo |
| Q34463612 | TGF-β3-expressing CD4+CD25(-)LAG3+ regulatory T cells control humoral immune responses |
| Q59783966 | TNF-related ligands and their receptors |
| Q37640818 | TSPAN33 is a novel marker of activated and malignant B cells. |
| Q35858608 | TWEAK/Fn14 Signaling Involvement in the Pathogenesis of Cutaneous Disease in the MRL/lpr Model of Spontaneous Lupus. |
| Q73789814 | Tamoxifen alleviates disease severity and decreases double negative T cells in autoimmune MRL-lpr/lpr mice |
| Q71794021 | Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver |
| Q42953771 | Targeting Notch signaling in autoimmune and lymphoproliferative disease |
| Q94445506 | Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice |
| Q71673360 | Tetrahydrobiopterin is a limiting factor of nitric oxide generation in interleukin 1 beta-stimulated rat glomerular mesangial cells |
| Q35189911 | Tetramers reveal IL-17-secreting CD4+ T cells that are specific for U1-70 in lupus and mixed connective tissue disease. |
| Q33766466 | Th1 CD4+ lymphocytes delete activated macrophages through the Fas/APO-1 antigen pathway |
| Q41096065 | Th1 and Th2 subsets equally undergo Fas-dependent and -independent activation-induced cell death |
| Q31143990 | The -844C/T polymorphism in the Fas ligand promoter associates with Taiwanese SLE. |
| Q38302171 | The APO-1/Fas (CD95) receptor is expressed in homozygous MRL/lpr mice |
| Q48011135 | The Fas antigen and Fas-mediated apoptosis in B-cell differentiation |
| Q24621785 | The Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cells |
| Q36114138 | The Fas/CD95 Receptor Regulates the Death of Autoreactive B Cells and the Selection of Antigen-Specific B Cells |
| Q40393393 | The Genetic Basis of Autoimmune Disease in MRL-lpr/lpr Mice |
| Q34420235 | The NOD mouse as a model of SLE. |
| Q53933125 | The Naive B Cell Repertoire Predisposes to Antigen-Induced Systemic Lupus Erythematosus |
| Q41334206 | The TNF-ligand and receptor superfamilies: controllers of immunity and the Trojan horses of autoimmune disease? |
| Q34779998 | The U1-snRNP complex: structural properties relating to autoimmune pathogenesis in rheumatic diseases |
| Q72463290 | The Yaa gene-dependent B-cell deficiency worsens the generalized lymphadenopathy and autoimmunity of C57BL/6-gld male mice |
| Q47680947 | The absence of CD44 ameliorates Fas(lpr/lpr) disease |
| Q83477877 | The absence of immunoglobulin D B cell receptor-mediated signals promotes the production of autoantibodies and exacerbates glomerulonephritis in murine lupus |
| Q34131476 | The apoptosis-1/Fas protein in human systemic lupus erythematosus |
| Q34283820 | The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes |
| Q38990736 | The contribution of the programmed cell death machinery in innate immune cells to lupus nephritis |
| Q35579076 | The current concept of T (h) 17 cells and their expanding role in systemic lupus erythematosus |
| Q36362018 | The defect in Fas mRNA expression in MRL/lpr mice is associated with insertion of the retrotransposon, ETn |
| Q35294513 | The dysregulation of cytokine networks in systemic lupus erythematosus |
| Q64964840 | The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity. |
| Q34148175 | The genetics of systemic lupus erythematosus: putting the pieces together |
| Q29977762 | The human autoantigen MCP1 is required during early stages of DNA replication |
| Q40743666 | The immunogenetics of glomerulonephritis |
| Q36362485 | The induction of experimental autoimmune myocarditis in mice lacking CD4 or CD8 molecules [corrected]. |
| Q37631369 | The inflammatory role of phagocyte apoptotic pathways in rheumatic diseases. |
| Q45304523 | The keratan sulfate disaccharide Gal(6S03) beta1,4-GlcNAc(6S03) modulates interleukin 12 production by macrophages in murine Thy-1 type autoimmune disease |
| Q35161112 | The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane |
| Q35646213 | The lupus-prone BXSB strain: the Yaa gene model of systemic lupus erythematosus |
| Q73958834 | The lymphoproliferation mutation in Fas locally unfolds the Fas death domain |
| Q34205697 | The many roles of FAS receptor signaling in the immune system |
| Q33836041 | The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutations |
| Q50975972 | The molecular signature of murine T cell homeostatic proliferation reveals both inflammatory and immune inhibition patterns. |
| Q28139188 | The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity |
| Q28585701 | The peroxisome proliferator-activated receptor gamma agonist rosiglitazone ameliorates murine lupus by induction of adiponectin |
| Q71517030 | The phosphotyrosine phosphatase inhibitor-phenylarsine oxide restores defective phosphoinositide hydrolysis response in anergic C3H-gld/gld lymphocytes |
| Q36090331 | The potential of Fas ligand (apoptosis-inducing molecule) as an unconventional therapeutic target in type 1 diabetes |
| Q35176329 | The regulation and activation potential of autoreactive B cells |
| Q40473992 | The relationship between inflammation and regeneration in the MRL mouse: potential relevance for putative human regenerative(scarless wound healing) capacities? |
| Q33781851 | The relative role of lymphocyte granule exocytosis versus death receptor-mediated cytotoxicity in viral pathophysiology |
| Q33685257 | The rise and fall of long-lived humoral immunity: terminal differentiation of plasma cells in health and disease |
| Q33636111 | The role of Fas and related death receptors in autoimmune and other disease states |
| Q37397437 | The role of IL-23/IL-17 axis in lupus nephritis |
| Q41593886 | The role of antibodies to DNA in systemic lupus erythematosus--a review and introduction to an international workshop on DNA antibodies held in London, May 1996. |
| Q33787902 | The role of apoptosis in systemic lupus erythematosus. |
| Q36366817 | The role of cell-mediated cytotoxicity in acute GVHD after MHC-matched allogeneic bone marrow transplantation in mice |
| Q33898921 | The role of fas ligand in vivo as a cause and regulator of pathogenesis |
| Q36366549 | The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice |
| Q36362801 | The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orall |
| Q40635201 | The role of the Yaa gene in lupus syndrome |
| Q41659044 | The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy |
| Q46110412 | The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice. |
| Q34602545 | The significance of immunohistochemistry in the diagnosis and therapy of neoplasms |
| Q33747849 | The spectrum of apoptotic defects and clinical manifestations, including systemic lupus erythematosus, in humans with CD95 (Fas/APO-1) mutations |
| Q37852758 | The tumour necrosis factor/TNF receptor superfamily: therapeutic targets in autoimmune diseases |
| Q34292932 | The understanding of contact-dependent T-cell helper function in molecular, cellular and physiological detail |
| Q74237719 | Therapeutic neutralization of CD95-ligand and TNF attenuates brain damage in stroke |
| Q35547592 | Therapeutic potential of CD8+ cytotoxic T lymphocytes in SLE |
| Q71930264 | Thiols prevent Fas (CD95)-mediated T cell apoptosis by down-regulating membrane Fas expression |
| Q74171891 | Thymocyte glucocorticoid resistance alters positive selection and inhibits autoimmunity and lymphoproliferative disease in MRL-lpr/lpr mice |
| Q33955244 | Thyroid cell apoptosis. A new understanding of thyroid autoimmunity |
| Q36851869 | Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens. |
| Q37541469 | Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction. |
| Q36403146 | Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus |
| Q35209364 | Tracking death dealing by Fas and TRAIL in lymphatic neoplastic disorders: pathways, targets, and therapeutic tools |
| Q36375875 | Tumor necrosis factor sustains the generalized lymphoproliferative disorder (gld) phenotype |
| Q34360681 | Type I interferons and limitin: a comparison of structures, receptors, and functions |
| Q36974265 | Understanding B-cell tolerance through the use of immunoglobulin transgenic models |
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