CXCR5 is critically involved in progression of lupus through regulation of B cell and double-negative T cell trafficking

scientific article

CXCR5 is critically involved in progression of lupus through regulation of B cell and double-negative T cell trafficking is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/CEI.12791
P932PMC publication ID4908294
P698PubMed publication ID26990531

P2093author name stringN Wagner
F Tacke
A Schippers
K Tenbrock
T Ostendorf
A Wiener
K Ohl
N Honke
P2860cites workA chemokine-driven positive feedback loop organizes lymphoid folliclesQ28142202
A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleenQ28300225
Follicular helper CD4 T cells (TFH)Q29615063
IL-2 protects lupus-prone mice from multiple end-organ damage by limiting CD4-CD8- IL-17-producing T cellsQ34053939
T cells as therapeutic targets in SLE.Q34075552
Ectopic lymphoid organogenesis: a fast track for autoimmunityQ34363840
Inhibition of aberrant circulating Tfh cell proportions by corticosteroids in patients with systemic lupus erythematosusQ34532672
Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative diseaseQ34602392
Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneysQ34892862
CD4(-)CD8(-) T-cells in primary Sjögren's syndrome: association with the extent of glandular involvementQ35086094
Characterization of a novel and spontaneous mouse model of inflammatory arthritisQ35617627
Pathogenetic role of glomerular CXCL13 expression in lupus nephritis.Q51723759
Systemic lupus erythematosus.Q53202066
Serum BLC/CXCL13 concentrations and renal expression of CXCL13/CXCR5 in patients with systemic lupus erythematosus and lupus nephritis.Q53356773
Circulating CXCR5+CD4+helper T cells in systemic lupus erythematosus patients share phenotypic properties with germinal center follicular helper T cells and promote antibody production.Q53618640
Increased serum levels of soluble L-selectin (CD62L) in patients with active systemic lupus erythematosus (SLE)Q56907703
Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosusQ61411628
Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppressionQ73977252
Analysis and classification of B-cell infiltrates in lupus and ANCA-associated nephritisQ81402177
Aberrant high expression of B lymphocyte chemokine (BLC/CXCL13) by C11b+CD11c+ dendritic cells in murine lupus and preferential chemotaxis of B1 cells towards BLCQ95721431
Double negative regulatory T cells in transplantation and autoimmunity: recent progress and future directionsQ35716736
Mechanisms of B cell autoimmunity in SLE.Q35840704
Programmed cell death 1 and Helios distinguish TCR-αβ+ double-negative (CD4-CD8-) T cells that derive from self-reactive CD8 T cellsQ35856318
Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell toleranceQ36041818
cAMP-responsive element modulator α (CREMα) trans-represses the transmembrane glycoprotein CD8 and contributes to the generation of CD3+CD4-CD8- T cells in health and diseaseQ37272180
The role of IL-23/IL-17 axis in lupus nephritisQ37397437
cAMP responsive element modulator (CREM) α mediates chromatin remodeling of CD8 during the generation of CD3+ CD4- CD8- T cellsQ37511786
B-cell depletion in the treatment of lupus nephritisQ38026784
CXCL13 as a new biomarker of systemic lupus erythematosus and lupus nephritis - from bench to bedside?Q38241317
Interleukin-2 treatment reverses effects of cAMP-responsive element modulator α-over-expressing T cells in autoimmune-prone miceQ41147908
T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritisQ44381577
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)22-32
P577publication date2016-03-14
P1433published inClinical and Experimental ImmunologyQ15716708
P1476titleCXCR5 is critically involved in progression of lupus through regulation of B cell and double-negative T cell trafficking
P478volume185

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cites work (P2860)
Q55266643CD11c-Specific Deletion Reveals CREB as a Critical Regulator of DC Function during the Germinal Center Response.
Q26741199Chemokines and Chemokine Receptors in the Development of Lupus Nephritis
Q39218839Research and therapeutics-traditional and emerging therapies in systemic lupus erythematosus
Q47136733Stabilized β-Catenin Ameliorates ALPS-Like Symptoms of B6/lpr Mice
Q39609044TCF1 deficiency ameliorates autoimmune lymphoproliferative syndrome (ALPS)-like phenotypes of lpr/lpr mice.
Q47095273The correlational research among serum CXCL13 levels, circulating plasmablasts and memory B cells in patients with systemic lupus erythematosus: A STROBE-compliant article

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