review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1177/096120339700600316 |
P698 | PubMed publication ID | 9296771 |
P50 | author | David A. Isenberg | Q42326409 |
P2093 | author name string | A Rahman | |
J Kalsi | |||
C T Ravirajan | |||
P2860 | cites work | An autoantibody to single-stranded DNA: Comparison of the three-dimensional structures of the unliganded fab and a deoxynucleotide-fab complex | Q27644751 |
Conformations of immunoglobulin hypervariable regions | Q28273335 | ||
The double edged sword of the immune response: mutational analysis of a murine anti-pneumococcal, anti-DNA antibody | Q28378842 | ||
Somatic generation of antibody diversity | Q29616439 | ||
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis | Q29618601 | ||
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis | Q30080034 | ||
Preferential utilization of conserved immunoglobulin heavy chain variable gene segments during human fetal life | Q33739586 | ||
Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen | Q33896641 | ||
Serological and genetic characterization of a human monoclonal immunoglobulin G anti-DNA idiotype | Q34141241 | ||
The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus | Q34234795 | ||
The human immunoglobulin VH repertoire | Q34312904 | ||
Modeling antibody hypervariable loops: a combined algorithm. | Q34322701 | ||
Human autoantibody recognition of DNA | Q34475971 | ||
Origins of anti-DNA autoantibodies | Q34528072 | ||
Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease | Q34602392 | ||
The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane | Q35161112 | ||
Antibodies specific for left-handed Z-DNA. | Q35377853 | ||
Generation of a fusion partner to sample the repertoire of splenic B cells destined for apoptosis | Q35486835 | ||
A recognition site on synthetic helical oligonucleotides for monoclonal anti-native DNA autoantibody | Q35611954 | ||
Concepts of pathogenesis of systemic lupus erythematosus | Q36140631 | ||
Molecular characteristics of antibodies bearing an anti-DNA-associated idiotype | Q36230634 | ||
Both IgM and IgG anti-DNA antibodies are the products of clonally selective B cell stimulation in (NZB x NZW)F1 mice | Q36231704 | ||
A monoclonal anti-DNA antibody also binds to cell-surface protein(s) | Q36263319 | ||
An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity | Q36270017 | ||
Genetic studies of autoimmunity and retrovirus expression in crosses of New Zealand black mice I. Xenotropic virus | Q36340026 | ||
Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains | Q36342054 | ||
Identification of a B cell differentiation factor(s) spontaneously produced by proliferating T cells in murine lupus strains of the lpr/lpr genotype | Q36347442 | ||
Immunochemical similarities between monoclonal antibacterial Waldenstrom's macroglobulins and monoclonal anti-DNA lupus autoantibodies | Q36350070 | ||
Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation | Q36350233 | ||
Induction of a cationic shift in IgG anti-DNA autoantibodies. Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis | Q36352584 | ||
Autoantibodies encoded by the most Jh-proximal human immunoglobulin heavy chain variable region gene | Q36356822 | ||
Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus | Q36361685 | ||
Mutational analysis of an autoantibody: differential binding and pathogenicity | Q36363653 | ||
The Fas protein is expressed at high levels on CD4+CD8+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr | Q36648389 | ||
An analysis of apoptosis in lymphoid organs and lupus disease in murine systemic lupus erythematosus (SLE). | Q36807788 | ||
Production of autoantibodies by human-human hybridomas | Q36985613 | ||
Charge of circulating immune complexes as a factor in glomerular basement membrane localization in mice | Q36998449 | ||
Ligand recognition by murine anti-DNA autoantibodies. II. Genetic analysis and pathogenicity | Q37353912 | ||
The three dimensional structure of a combining region-ligand complex of immunoglobulin NEW at 3.5-A resolution | Q37440019 | ||
Immunization of rabbits with purified RNA polymerase I induces a distinct population of antibodies against nucleic acids as well as anti-RNA polymerase I antibodies, both characteristic of systemic lupus erythematosus | Q37535169 | ||
Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity | Q37568701 | ||
Acquisition of immunologic self-tolerance | Q38254157 | ||
The developmental biology of T lymphocytes | Q39647331 | ||
A comparative immunologic analysis of several murine strains with autoimmune manifestations | Q40217020 | ||
Immunogenic DNA-related factors. Nucleosomes spontaneously released from normal murine lymphoid cells stimulate proliferation and immunoglobulin synthesis of normal mouse lymphocytes | Q40347118 | ||
The origin, sequence, structure, and consequences of developing anti-DNA antibodies. A human perspective | Q40387098 | ||
MRL-lpr/lpr disease: theories meet Fas. | Q40388330 | ||
Fas and Fas ligand: lpr and gld mutations | Q40398275 | ||
Somatic hypermutation | Q40404787 | ||
Gld and lpr mice: single gene mutant models for failed self tolerance | Q40635205 | ||
Genetic and structural evidence for antigen selection of anti-DNA antibodies. | Q40661152 | ||
Anti-dsdna and complement profiles as prognostic guides in systemic lupus erythematosus | Q40703151 | ||
Development of the T cell receptor repertoire in lpr mice | Q40745038 | ||
The role of B cell abnormalities in the systemic autoimmune syndromes of lpr and gld mice | Q40745058 | ||
Programmed cell death, apoptosis and killer genes | Q40813094 | ||
Activation-induced cell death (apoptosis) of mature peripheral T lymphocytes | Q40841803 | ||
Measurement of increases in anti-double-stranded DNA antibody levels as a predictor of disease exacerbation in systemic lupus erythematosus. A long-term, prospective study | Q41192552 | ||
Significance of enzyme linked immunosorbent assay (ELISA) for antibodies to double stranded and single stranded DNA in patients with lupus nephritis: correlation with severity of renal histology | Q41258120 | ||
Immunological studies concerning the nephritis of systemic lupus erythematosus | Q41510128 | ||
Production and analysis of IgG monoclonal anti-DNA antibodies from systemic lupus erythematosus (SLE) patients | Q41563555 | ||
Structure and physical map of 64 variable segments in the 3'0.8-megabase region of the human immunoglobulin heavy-chain locus | Q41579779 | ||
Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus | Q41697487 | ||
Structural repertoire of the human VH segments | Q42603998 | ||
A unique sequence of the NZW I-E beta chain and its possible contribution to autoimmunity in the (NZB x NZW)F1 mouse | Q42939797 | ||
Crystallographic characterization of the Fab fragment of a monoclonal anti-ss-DNA antibody | Q44460487 | ||
Comparison of pathogenic and non-pathogenic murine antibodies to DNA: antigen binding and structural characteristics | Q46466571 | ||
Antigen-binding diversity of human hybridoma autoantibodies derived from splenocytes of patients with SLE | Q46986045 | ||
Functional and modelling studies of the binding of human monoclonal anti-DNA antibodies to DNA. | Q47629955 | ||
Anti-DNA and anti-platelet specificities of SLE-derived autoantibodies: evidence for CDR2H mutations and CDR3H motifs | Q48072431 | ||
Molecular analyses of anti-DNA antibodies induced by polyomavirus BK in BALB/c mice | Q48073121 | ||
A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q. | Q48082296 | ||
Identification and characterization of a new human DNA reactive monoclonal antibody and a common idiotype, WRI 176 Id beta | Q48085430 | ||
Variable region sequences of autoantibodies from mice with experimental systemic lupus erythematosus | Q48113515 | ||
Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas | Q48166985 | ||
Early restriction of the human antibody repertoire | Q48335513 | ||
Molecular modeling of antibody combining sites. | Q52464878 | ||
Analysis of immunoglobulin variable region genes of a human IgM anti-myeloperoxidase antibody derived from a patient with vasculitis. | Q53793455 | ||
Detection of cross-reactive anti-DNA antibody idiotypes in the serum of systemic lupus erythematosus patients and of their relatives | Q57089850 | ||
The Imprint of Somatic Hypermutation on the Repertoire of Human Germline V Genes | Q57444253 | ||
Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures | Q59070003 | ||
Mechanism of antigen-driven selection in germinal centres | Q59072211 | ||
The role of clonal selection and somatic mutation in autoimmunity | Q59082893 | ||
P433 | issue | 3 | |
P921 | main subject | antibody | Q79460 |
workshop | Q27556165 | ||
P304 | page(s) | 290-304 | |
P577 | publication date | 1997-01-01 | |
P1433 | published in | Lupus | Q6704846 |
P1476 | title | The role of antibodies to DNA in systemic lupus erythematosus--a review and introduction to an international workshop on DNA antibodies held in London, May 1996. | |
P478 | volume | 6 |
Q53877182 | A human anti-dsDNA monoclonal antibody caused hyaline thrombi formation in kidneys of 'leaky' SCID mice. |
Q44183280 | An open study of B lymphocyte depletion in systemic lupus erythematosus |
Q83459571 | Anti-C1q antibodies are associated with systemic lupus erythematosus disease activity and lupus nephritis in northeast of China |
Q35555256 | Anti-C1q antibodies in nephritis: correlation between titres and renal disease activity and positive predictive value in systemic lupus erythematosus |
Q84372154 | Anti-C1q antibody is a valuable biological marker for prediction of renal pathological characteristics in lupus nephritis |
Q35045844 | Anti-DNA antibodies--overview of assays and clinical correlations |
Q88161098 | Antibody repertoire analysis in polygenic autoimmune diseases |
Q33361142 | B cell depletion in autoimmune disease |
Q33828017 | Early diagnosis of systemic lupus erythmatosus using ANN models of dsDNA binding antibody sequence data |
Q33217667 | Elevated immunoglobulin levels in the cerebrospinal fluid from lupus-prone mice |
Q24804411 | Is closer linkage between systemic lupus erythematosus and anti-double-stranded DNA antibodies a desirable and attainable goal? |
Q84449235 | Nonrenal and renal activity of systemic lupus erythematosus: a comparison of two anti-C1q and five anti-dsDNA assays and complement C3 and C4 |
Q40680465 | Nucleosomes possess a high affinity for glomerular laminin and collagen IV and bind nephritogenic antibodies in murine lupus-like nephritis |
Q38297315 | Pre-treatment affinity for LJP 394 influences pharmacodynamic response in lupus patients |
Q84700980 | Prevalence and clinical significance of 15 autoantibodies in patients with new-onset systemic lupus erythematosus |
Q64388631 | Prior anti-dsDNA antibody status does not predict later disease manifestations in systemic lupus erythematosus |
Q30839172 | Production and characterization of human monoclonal anti-idiotype antibodies to anti-dsDNA antibodies |
Q77719715 | SLE autoantibodies binding to native calf thymus DNA brominated in high salt |
Q44439756 | Simultaneous positivity for anti-DNA, anti-nucleosome and anti-histone antibodies is a marker for more severe lupus nephritis |
Q56897860 | Suppressive oligodeoxynucleotides delay the onset of glomerulonephritis and prolong survival in lupus-prone NZB × NZW mice |
Q42953771 | Targeting Notch signaling in autoimmune and lymphoproliferative disease |
Q33716669 | The role of B cells in lupus pathogenesis |
Q77525403 | The role of in vitro expression systems in the investigation of antibodies to DNA |
Q31125361 | The role of somatic mutation in determining the affinity of anti-DNA antibodies. |
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