Origin and diversification of the clonogenic cell in multiple myeloma: lessons from the immunoglobulin repertoire

scientific article

Origin and diversification of the clonogenic cell in multiple myeloma: lessons from the immunoglobulin repertoire is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1050266486
P356DOI10.1038/SJ.LEU.2401908
P698PubMed publication ID11021746
P5875ResearchGate publication ID12301573

P2093author name stringYataganas X
Kollia P
Kosmas C
Stamatopoulos K
Viniou N
Zoi K
Stavroyianni N
Belessi C
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Characterization of the immunoglobulin light chain variable region gene expressed in multiple myelomaQ74476207
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Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3Q28242697
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Unusual patterns of immunoglobulin gene rearrangement and expression during human B cell ontogeny: human B cells can simultaneously express cell surface kappa and lambda light chainsQ36361880
The bone marrow of multiple myeloma patients contains B cell populations at different stages of differentiation that are clonally related to the malignant plasma cellQ36362222
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Bence Jones proteins and light chains of immunoglobulins. Preferential association of the V lambda VI subgroup of human light chains with amyloidosis AL (lambda).Q37016453
Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myelomaQ37148117
The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacementQ40626080
Negative selection of lymphocytesQ40807431
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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cellsQ40972355
Clonal selection and learning in the antibody systemQ41002744
The molecular basis of somatic hypermutation of immunoglobulin genesQ41049026
Quantitation of circulating peripheral blood plasma cells and their relationship to disease activity in patients with multiple myelomaQ41073565
Markers of multiple hematopoietic-cell lineages in multiple myelomaQ41196868
Transfer of myeloma idiotype-specific immunity from an actively immunised marrow donorQ41349219
Interaction of tumor and host cells with adhesion and extracellular matrix molecules in the development of multiple myelomaQ41396622
Idiotype/granulocyte-macrophage colony-stimulating factor fusion protein as a vaccine for B-cell lymphomaQ41559182
The systemic amyloidosesQ41596634
The normal counterpart of IgD myeloma cells in germinal center displays extensively mutated IgVH gene, Cmu-Cdelta switch, and lambda light chain expressionQ41853009
Evidence for a bone marrow B cell transcribing malignant plasma cell VDJ joined to C mu sequence in immunoglobulin (IgG)- and IgA-secreting multiple myelomasQ42614266
Analysis of the kappa light chain variable region in multiple myelomaQ42636552
Somatic hypermutation of immunoglobulin variable region genes: focus on follicular lymphoma and multiple myelomaQ42678196
Antibody engineering for the analysis of affinity maturation of an anti-hapten response.Q42735546
Induction of immune responses in patients with B-cell lymphoma against the surface-immunoglobulin idiotype expressed by their tumorsQ43475849
DNA immunization induces protective immunity against B-cell lymphomaQ46694174
P433issue10
P921main subjectmultiple myelomaQ467635
P304page(s)1718-1726
P577publication date2000-10-01
P1433published inLeukemiaQ6534498
P1476titleOrigin and diversification of the clonogenic cell in multiple myeloma: lessons from the immunoglobulin repertoire
P478volume14

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cites work (P2860)
Q37101674Anti-CD20 monoclonal antibody therapy in multiple myeloma.
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Q54771689Incomplete DJH rearrangements as a novel tumor target for minimal residual disease quantitation in multiple myeloma using real-time PCR.
Q47791159Incomplete DJH rearrangements of the IgH gene are frequent in multiple myeloma patients: immunobiological characteristics and clinical implications.
Q36872779Molecular genetic analysis of haematological malignancies II: Mature lymphoid neoplasms
Q89582276Molecular profiling of immunoglobulin heavy-chain gene rearrangements unveils new potential prognostic markers for multiple myeloma patients
Q43780118Somatic hypermutation targeting to intrinsic hotspots of immunoglobulin genes in follicular lymphoma and multiple myeloma.
Q37948866Therapeutic potential of CCR1 antagonists for multiple myeloma.
Q86848592[Application of BIOMED- 2 standardized Ig gene rearrangement system in multiple myeloma]