| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1146/ANNUREV.PA.22.040182.002505 |
| P953 | full work available at URL | https://www.annualreviews.org/doi/pdf/10.1146/annurev.pa.22.040182.002505 |
| P3181 | OpenCitations bibliographic resource ID | 1849045 |
| P698 | PubMed publication ID | 6282188 |
| P2093 | author name string | A. Poland | |
| J. C. Knutson | |||
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | pharmacology | Q128406 |
| P304 | page(s) | 517-54 | |
| P577 | publication date | 1982-01-01 | |
| P1433 | published in | Annual Review of Pharmacology and Toxicology | Q567365 |
| P1476 | title | 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity | |
| 2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity | |||
| P478 | volume | 22 |
| Q70150157 | 1-amino-3,7,8-trichlorodibenzo-p-dioxin: a specific antagonist for TCDD-induced myelotoxicity |
| Q34638914 | 12th meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals: susceptibility to environmental hazards |
| Q42915368 | 2,3,4,7,8-pentachlorodibenzofuran is a more potent cytochrome P4501A inducer than 2,3,7,8-tetrachlorodibenzo-p-dioxin in herring gull hepatocyte cultures |
| Q28373922 | 2,3,7,8 Tetrachlorodibenzo-p-dioxin induction of cytochrome P4501A in cultured rat and human hepatocytes |
| Q50188454 | 2,3,7,8 Tetrachlorodibenzodioxin in fish from the pigeon river of Eastern Tennessee, USA: Its toxicity and mutagenicity as revealed by the Ames Salmonella assay |
| Q54447595 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and 2,3,7,8-tetrachlorodibenzofuran (TCDF) in pregnant C57BL/6N mice: distribution to the embryo and excretion. |
| Q36899159 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and Related Compounds as Antioestrogens: Characterization and Mechanism of Action |
| Q35035961 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) as a potent and persistent thyroxine agonist: a mechanistic model for toxicity based on molecular reactivity |
| Q41100277 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) causes an Ah receptor-dependent and ARNT-independent increase in membrane levels and activity of p60(Src). |
| Q44663217 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced activation of mitogen-activated protein kinase signaling pathway in Jurkat T cells |
| Q41725049 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced changes in activities of nuclear protein kinases and phosphatases affecting DNA binding activity of c-Myc and AP-1 in the livers of guinea pigs |
| Q68010776 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced lipid peroxidation in genetically responsive and non-responsive mice |
| Q28361484 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin causes increases in expression of c-erb-A and levels of protein-tyrosine kinases in selected tissues of responsive mouse strains |
| Q42540117 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin co-stimulates staphylococcal enterotoxin beta (SEB) cytokine production and phenotypic cell cycling in Long-Evans rats |
| Q34208237 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin induced cell-specific drug transporters with acquired cisplatin resistance in cisplatin sensitive cancer cells. |
| Q40710980 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin is a possible activator of human cytomegalovirus replication in a human fibroblast cell line |
| Q68982009 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced lipid peroxidation in hepatic and extrahepatic tissues of male and female rats |
| Q28354266 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible aryl hydrocarbon receptor-mediated change in CYP1A1 chromatin structure occurs independently of transcription |
| Q42730146 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin: its effect on genes for mandible traits in mice. |
| Q40492964 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin: molecular mechanism of carcinogenesis and its implication in human in vitro model |
| Q47754692 | 2,3,7,8-Tetrafluorodibenzo-p-dioxin: a potent agonist of the murine dioxin receptor |
| Q34995999 | 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) poisoning in Victor Yushchenko: identification and measurement of TCDD metabolites |
| Q23919662 | 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway: role of the transcription activaton and DNA binding of AhR |
| Q54688604 | 3,3',4,4'-Tetrabromobiphenyl sensitizes rats to the hepatotoxic effects of endotoxin by a mechanism that involves more than tumor necrosis factor. |
| Q42207459 | 3,3',4,4'-tetrachloro[14C]biphenyl in pregnant mice: enrichment of phenol and methyl sulphone metabolites in late gestational fetuses |
| Q63377957 | 3,3′,4,4′-Tetrachlorobiphenyl oxidation in fish, bird and reptile species: relationship to cytochrome P450 1A inactivation and reactive oxygen production |
| Q28341699 | 3,4,3',4'-tetrachlorobiphenyl-induced effects in the rat liver. II. Electron microscopic autoradiographic localization of 3H-TCB |
| Q44490829 | 3-methylcholanthrene activates human immunodeficiency virus type 1 replication via aryl hydrocarbon receptor |
| Q43672556 | 7-Ethoxyresorufin O-deethylase induction in rainbow trout gill epithelium cultured on permeable supports: asymmetrical distribution of substrate metabolites |
| Q61470506 | A Comparison of Water Quality Criteria for the Great Lakes Based on Human and Wildlife Health |
| Q38707211 | A Molecular Mechanism To Switch the Aryl Hydrocarbon Receptor from a Transcription Factor to an E3 Ubiquitin Ligase. |
| Q73485988 | A Nuclear Localization Signal of Human Aryl Hydrocarbon Receptor Nuclear Translocator/Hypoxia-inducible Factor 1β Is a Novel Bipartite Type Recognized by the Two Components of Nuclear Pore-targeting Complex |
| Q43703051 | A Partnership Between the Dioxin Receptor and a Basic Helix-Loop-Helix Protein |
| Q57383549 | A Perspective on Biologically-Based Approaches to Dioxin Risk Assessment |
| Q34636467 | A QSAR evaluation of Ah receptor binding of halogenated aromatic xenobiotics |
| Q36244860 | A TDO2-AhR signaling axis facilitates anoikis resistance and metastasis in triple-negative breast cancer. |
| Q33792456 | A bistable switch underlying B-cell differentiation and its disruption by the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q40560925 | A comparative study of the regulation of cytochrome P-450 and glutathione transferase gene expression in rat liver |
| Q44327090 | A constitutively active aryl hydrocarbon receptor causes loss of peritoneal B1 cells |
| Q28387023 | A critical comparison of murine pathology and epidemiological data of TCDD, PCB126, and PeCDF |
| Q23919658 | A cycloheximide-sensitive factor regulates TCDD-induced degradation of the aryl hydrocarbon receptor |
| Q28280266 | A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle |
| Q46632130 | A histochemical and pathological study on the interrelationship between TCDD-induced AhR expression, AhR activation, and hepatotoxicity in mice. |
| Q34018779 | A hypomorphic allele of aryl hydrocarbon receptor-associated protein-9 produces a phenocopy of the AHR-null mouse |
| Q42536276 | A malignant transformation of human cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin exhibits altered expressions of growth regulatory factors |
| Q28306680 | A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q35776751 | A novel nonconsensus xenobiotic response element capable of mediating aryl hydrocarbon receptor-dependent gene expression |
| Q41107424 | A point mutation responsible for defective function of the aryl-hydrocarbon-receptor nuclear translocator in mutant Hepa-1c1c7 cells |
| Q38531332 | A sensitive, rapid, and simple DR-EcoScreen bioassay for the determination of PCDD/Fs and dioxin-like PCBs in environmental and food samples |
| Q40722710 | A survey of dioxin-like contaminants in fish from recreational fishing. |
| Q55340353 | Aberrant CYP1A1 induction: discrepancy of CYP1A1 mRNA and aryl hydrocarbon hydroxylase activity in mutant cells of mouse hepatoma line, Hepa-1. |
| Q36927028 | Abnormal liver development and resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in mice carrying a mutation in the DNA-binding domain of the aryl hydrocarbon receptor. |
| Q41500833 | Absence of lipid peroxidation as determined by ethane exhalation in rats treated with 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD). |
| Q28359809 | Absence of positive co-operativity in the binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin to its cytosolic receptor protein |
| Q72384113 | Accumulation and persistence of individual polychlorinated biphenyl congeners in liver, blood, and adipose tissue of rats following dietary exposure to Aroclor 1254 |
| Q33634245 | Activation of the aryl-hydrocarbon receptor inhibits invasive and metastatic features of human breast cancer cells and promotes breast cancer cell differentiation |
| Q46022262 | Activation of transcription as a general mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin action. |
| Q42223955 | Acute toxicity in the guinea pig and in vitro "dioxin-like" activity of the environmental contaminant 1,2,4,5,7,8-hexachloro (9H)xanthene |
| Q68254568 | Acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin to mink |
| Q35574602 | Advances in analytical techniques for polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and dioxin-like PCBs |
| Q28383178 | Adverse effects in adulthood resulting from low-level dioxin exposure in juvenile zebrafish |
| Q27921845 | Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment |
| Q36139135 | Agonist and chemopreventative ligands induce differential transcriptional cofactor recruitment by aryl hydrocarbon receptor |
| Q38330069 | Ah receptor and NF-kappaB interactions, a potential mechanism for dioxin toxicity |
| Q34815793 | Ah receptor and NF-kappaB interactions: mechanisms and physiological implications |
| Q37663370 | Ah receptor-mediated suppression of liver regeneration through NC-XRE-driven p21Cip1 expression |
| Q34660185 | Ah receptor: relevance of mechanistic studies to human risk assessment |
| Q68209508 | Alterations in the cortical thymic epithelium of rats after in vivo exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): An (immuno)histological study |
| Q73781716 | Alterations in the developing immune system of the F344 rat after perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin I. [correction of II]. Effects on the fetus and the neonate |
| Q69688238 | Alterations in vitamin A metabolism by polyhalogenated aromatic hydrocarbons |
| Q68323654 | Alterations of hepatic acetyl-CoA carboxylase by 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q40412410 | Altered gene expression in human cells induced by the agricultural chemical Enable |
| Q23922213 | Altered gene expression in human cells treated with the insecticide diazinon: correlation with decreased DNA excision repair capacity |
| Q45106187 | Altered hepatic iron distribution and release in rats after exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). |
| Q46225042 | Altered in vivo toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in C-SRC deficient mice |
| Q60054002 | An imazamox-based herbicide causes apoptotic changes in rat liver and pancreas |
| Q57409035 | An in vitro rainbow trout cell bioassay for aryl hydrocarbon receptor-mediated toxins |
| Q34413378 | An integrated genomic analysis of aryl hydrocarbon receptor-mediated inhibition of B-cell differentiation |
| Q31012928 | An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q44094044 | Analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced gene expression profile in vivo using pathway-specific cDNA arrays |
| Q35035426 | Analysis of polychlorinated dibenzofurans, dioxins and related compounds in environmental samples |
| Q67239025 | Analysis of polychlorobiphenyl congeners in Wisconsin fish |
| Q71951714 | Analysis of structural requirements for Ah receptor antagonist activity: ellipticines, flavones, and related compounds |
| Q39658987 | Analysis of the CYP1A1 mRNA Dose-Response in Human Keratinocytes Indicates that Relative Potencies of Dioxins, Furans, and PCBs Are Species and Congener Specific |
| Q40916857 | Analysis of the murine AhR gene promoter |
| Q28390140 | Animal models of human response to dioxins |
| Q40665098 | Antagonism of aryl hydrocarbon receptor-dependent induction of CYP1A1 and inhibition of IgM expression by di-ortho-substituted polychlorinated biphenyls |
| Q41199568 | Antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin are mediated by direct transcriptional interference with the liganded estrogen receptor. Cross-talk between aryl hydrocarbon- and estrogen-mediated signaling |
| Q54207899 | Antioxidant compounds in the seaweed Gelidiella acerosa protects human Peripheral Blood Mononuclear Cells against TCDD induced toxicity. |
| Q73344250 | Apolipoprotein A-I gene expression is upregulated by polychlorinated biphenyls in rat liver |
| Q24812775 | Application of genomics to toxicology research |
| Q44172844 | Application of the luciferase recombinant cell culture bioassay system for the analysis of polycyclic aromatic hydrocarbons |
| Q35030800 | Applications of physiologic pharmacokinetic modeling in carcinogenic risk assessment |
| Q44547059 | Area under the curve as a dose metric for promotional responses following 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure |
| Q71843940 | Aromatic hydrocarbon receptor in cultured fetal cells from C57BL/6J and DBA/2J mice: similarity in molecular mass to receptors in adult livers |
| Q38336259 | Aromatic hydrocarbon receptor polymorphism: development of new methods to correlate genotype with phenotype |
| Q92894585 | Aryl Hydrocarbon Receptor (AhR) Ligands as Selective AhR Modulators: Genomic Studies |
| Q47292774 | Aryl Hydrocarbon Receptor Activation Suppresses EBF1 and PAX5 and Impairs Human B Lymphopoiesis. |
| Q36727433 | Aryl Hydrocarbon Receptor Plays Protective Roles against High Fat Diet (HFD)-induced Hepatic Steatosis and the Subsequent Lipotoxicity via Direct Transcriptional Regulation of Socs3 Gene Expression |
| Q36745322 | Aryl hydrocarbon receptor (AHR) regulation of L-Type Amino Acid Transporter 1 (LAT-1) expression in MCF-7 and MDA-MB-231 breast cancer cells |
| Q51220592 | Aryl hydrocarbon receptor activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs human B lymphopoiesis. |
| Q33860725 | Aryl hydrocarbon receptor activation by cAMP vs. dioxin: divergent signaling pathways |
| Q37048317 | Aryl hydrocarbon receptor activation by dioxin targets phosphoenolpyruvate carboxykinase (PEPCK) for ADP-ribosylation via 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly(ADP-ribose) polymerase (TiPARP). |
| Q64059188 | Aryl hydrocarbon receptor acts as a tumor suppressor in a syngeneic MC38 colon carcinoma tumor model |
| Q40232048 | Aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha in MCF-7 breast cancer cells. |
| Q57096209 | Aryl hydrocarbon receptor and intestinal immunity |
| Q37167304 | Aryl hydrocarbon receptor and lung cancer |
| Q39847613 | Aryl hydrocarbon receptor inhibition downregulates the TGF-beta/Smad pathway in human glioblastoma cells |
| Q45964613 | Aryl hydrocarbon receptor is an ozone sensor in human skin. |
| Q36448857 | Aryl hydrocarbon receptor-dependence of dioxin's effects on constitutive mouse hepatic cytochromes P450 and growth hormone signaling components |
| Q24538933 | Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types |
| Q35550990 | Aryl hydrocarbon receptor-mediated induction of Stearoyl-CoA desaturase 1 alters hepatic fatty acid composition in TCDD-elicited steatosis |
| Q41429404 | Aryl hydrocarbon receptor-mediated signal transduction |
| Q34815809 | Aryl hydrocarbon receptors: diversity and evolution |
| Q34829134 | Aryl hydrocarbon-induced interactions at multiple DNA elements of diverse sequence--a multicomponent mechanism for activation of cytochrome P4501A1 (CYP1A1) gene transcription |
| Q68008591 | Assessment of biological activities of mixtures of polychlorinated dibenzo-p-dioxins (PCDDs) and their constituents in human HepG2 cells |
| Q68242428 | Assessment of biological activities of mixtures of polychlorinated dibenzo-p-dioxins: comparison between defined mixtures and their constituents |
| Q44555250 | Assessment of metabolites and AhR and CYP1A1 mRNA expression subsequent to prenatal exposure to inhaled benzo(a)pyrene |
| Q36138283 | Assignment of the human 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P1-450 gene to chromosome 15 |
| Q47215935 | Association between PCBs and lower embryonic weight in black-crowned night herons in San Francisco Bay. |
| Q36004704 | Association between the levels of biogenic amines and superoxide anion production in brain regions of rats after subchronic exposure to TCDD. |
| Q28281351 | Association of the dioxin receptor with the Mr 90,000 heat shock protein: a structural kinship with the glucocorticoid receptor |
| Q34200656 | Automated dose-response analysis and comparative toxicogenomic evaluation of the hepatic effects elicited by TCDD, TCDF, and PCB126 in C57BL/6 mice. |
| Q38888410 | Autophagy potentially protects against 2,3,7,8-tetrachlorodibenzo-p-Dioxin induced apoptosis in SH-SY5Y cells |
| Q59094233 | Benoxaprofen suppression of polychlorinated biphenyl toxicity without alteration of mixed function oxidase function |
| Q40476662 | Benzo[a]pyrene, 3-methylcholanthrene and beta-naphthoflavone induce oxidative stress in hepatoma hepa 1c1c7 Cells by an AHR-dependent pathway. |
| Q89073870 | Beyond the Aryl Hydrocarbon Receptor: Pathway Interactions in the Hepatotoxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Related Compounds |
| Q42200336 | Binding characteristics of 4-S proteins from rat and mouse liver. High affinity of ellipticines |
| Q44262417 | Binding characteristics of 4S PAH-binding protein and Ah receptor from rats and mice |
| Q42200334 | Binding characteristics of Ah receptors from rats and mice before and after separation from hepatic cytosols. 7-Hydroxyellipticine as a competitive antagonist of cytochrome P-450 induction |
| Q61782314 | Binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin to AH receptor in placentas from normal versus abnormal pregnancy outcomes |
| Q23911835 | Binding of aryl hydrocarbon receptor (AhR) to AhR-interacting protein - The role of hsp90 |
| Q34847222 | Binding of polychlorinated biphenyls to the aryl hydrocarbon receptor |
| Q28645942 | Binding of polycyclic aromatic hydrocarbons (PAHs) to teleost aryl hydrocarbon receptors (AHRs) |
| Q34471183 | Bioanalytical screening methods for dioxins and dioxin-like compounds a review of bioassay/biomarker technology |
| Q46832557 | Bioavailability and cytochrome P-450 induction from 2,3,7,8-tetrachlorodibenzo-P-dioxin contaminated soils from Times Beach, Missouri, and Newark, New Jersey |
| Q34086035 | Biochemical and toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in immature male and female chickens |
| Q69264130 | Biochemical and toxicological effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) congeners in female rats |
| Q40463191 | Biochemical effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds on the central nervous system |
| Q44237075 | Biological and chemical determination of dioxin-like compounds in sediments by means of a sediment triad approach in the catchment area of the river Neckar |
| Q50775265 | Biological effects of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in double-crested cormorant chicks (Phalacrocorax auritus). |
| Q24815975 | Biomarker measurements in a coastal fish-eating population environmentally exposed to organochlorines |
| Q34670985 | Biomarkers and bioassays for detecting dioxin-like compounds in the marine environment |
| Q37967145 | Biomolecular interactions and tools for their recognition: focus on the quartz crystal microbalance and its diverse surface chemistries and applications |
| Q28391548 | Bisphenol A inhibits cultured mouse ovarian follicle growth partially via the aryl hydrocarbon receptor signaling pathway |
| Q33787781 | Bone marrow lymphoid and myeloid progenitor cells are suppressed in 7,12-dimethylbenz(a)anthracene (DMBA) treated mice |
| Q41327667 | Both short- and long-term effects of nerve growth factor on tyrosine hydroxylase in calf adrenal chromaffin cells are blocked by S-adenosylhomocysteine hydrolase inhibitors |
| Q35593051 | CCAAT/ enhancer-binding protein β activation by capsaicin contributes to the regulation of CYP1A1 expression, mediated by the aryl hydrocarbon receptor |
| Q42803127 | CCAAT/enhancer-binding protein beta is not affected by tetrachlorodibenzo-p-dioxin (TCDD) inhibition of 3T3-L1 preadipocyte differentiation |
| Q34131886 | CH223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor |
| Q36485692 | CYP induction-mediated drug interactions: in vitro assessment and clinical implications |
| Q39015123 | CYP1A andother biomarker responses to effluents from a textile mill in the Volta River (Ghana) using caged tilapia (Oreochromis niloticus) andsediment-exposed mudfish (Clarias anguillaris). |
| Q36473507 | CYP1A in TCDD toxicity and in physiology-with particular reference to CYP dependent arachidonic acid metabolism and other endogenous substrates |
| Q23919665 | CYP1A induction and human risk assessment: an evolving tale of in vitro and in vivo studies |
| Q44082385 | CYP1A1 induction by pyridine and its metabolites in HepG2 cells |
| Q28259718 | CYP1A1: friend or foe? |
| Q34659087 | Calculation of 2,3,7,8-TCDD equivalent concentrations of complex environmental contaminant mixtures |
| Q34231307 | Cancer-promoting and Inhibiting Effects of Dietary Compounds: Role of the Aryl Hydrocarbon Receptor (AhR) |
| Q37218276 | Canola oil is an excellent vehicle for eliminating pesticide residues in aqueous ginseng extract |
| Q91976059 | Canonical and non-canonical aryl hydrocarbon receptor signaling pathways |
| Q34438479 | Carcinogenic risks of dioxin: mechanistic considerations |
| Q36627760 | Carcinogenicity of "non-dioxinlike" polychlorinated biphenyls |
| Q37886498 | Carcinogenicity of polyhalogenated biphenyls: PCBs and PBBs |
| Q50617474 | Cardiac toxicity by sublethal 2,3,7,8-tetrachlorodibenzo-p-dioxin correlates with its anti-proliferation effect on cardiomyocytes in zebrafish embryos. |
| Q44192985 | Cell bioassays for detection of aryl hydrocarbon (AhR) and estrogen receptor (ER) mediated activity in environmental samples |
| Q52591069 | Cell bioassays for detection of aryl hydrocarbon (AhR) and estrogen receptor (ER) mediated activity in environmental samples. |
| Q37090146 | Cell proliferation and oxidative stress pathways are modified in fibroblasts from Sturge-Weber syndrome patients |
| Q44188830 | Cell-type specificity of ectonucleotidase expression and upregulation by 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q70158390 | Cellular and genetic basis for suppression of cytotoxic T cell generation by haloaromatic hydrocarbons |
| Q41699289 | Changes in thyroid hormone economy following consumption of environmentally contaminated Great Lakes fish |
| Q59958277 | Chapter 7 Xenobiotic receptors in fish: Structural and functional diversity and evolutionary insights |
| Q33482542 | Characterization of MCF mammary epithelial cells overexpressing the Arylhydrocarbon receptor (AhR). |
| Q58100986 | Characterization of TCDD-Inducible Poly-ADP-Ribose Polymerase (TIPARP/ARTD14) Catalytic Activity |
| Q28507862 | Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development |
| Q67916375 | Characterization of an inducible aryl hydrocarbon receptor-like protein in rat liver |
| Q40760338 | Characterization of dioxin-like activity of sediments from a Czech river basin |
| Q38336078 | Characterization of multiple forms of the Ah receptor: recognition of a dioxin-responsive enhancer involves heteromer formation |
| Q41401124 | Characterization of polyclonal antibodies to the aromatic hydrocarbon receptor |
| Q41633478 | Characterization of the aryl hydrocarbon receptor in the human C-4II cervical squamous carcinoma cell line |
| Q38337434 | Characterization of the interaction of transformed rat hepatic cytosolic Ah receptor with a dioxin responsive transcriptional enhancer |
| Q28205293 | Characterization of the phosphorylation status of the hepatitis B virus X-associated protein 2 |
| Q41643801 | Chemical cross-linking of the cytosolic and nuclear forms of the Ah receptor in hepatoma cell line 1c1c7 |
| Q39477196 | Chloracne and chloracnegens |
| Q35129292 | Chlordecone altered hepatic disposition of [14C]cholesterol and plasma cholesterol distribution but not SR-BI or ABCG8 proteins in livers of C57BL/6 mice |
| Q44470074 | Chlordecone impairs Na+-stimulated l-[3H]glutamate transport and mobility of 16-doxyl stearate in rat liver plasma membrane vesicles |
| Q34019174 | Chlordecone increased subcellular distribution of scavenger receptor class B type II to murine hepatic microsomes without altering cytosolic cholesterol binding proteins |
| Q37106874 | Chlordecone, a mixed pregnane X receptor (PXR) and estrogen receptor alpha (ERalpha) agonist, alters cholesterol homeostasis and lipoprotein metabolism in C57BL/6 mice |
| Q24811813 | Chlorophyll derived from Chlorella inhibits dioxin absorption from the gastrointestinal tract and accelerates dioxin excretion in rats |
| Q28115715 | Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein |
| Q36003360 | Cobaltous chloride and hypoxia inhibit aryl hydrocarbon receptor-mediated responses in breast cancer cells |
| Q34500308 | Combinatorial bio/chemical analysis of dioxin and dioxin-like compounds in waste recycling, feed/food, humans/wildlife and the environment. |
| Q30778906 | Combining NMR spectral and structural data to form models of polychlorinated dibenzodioxins, dibenzofurans, and biphenyls binding to the AhR. |
| Q92770466 | Comparative Lethality of In ovo Exposure to PCB 126, PCB 77, and 2 Environmentally Relevant PCB Mixtures in Japanese Quail (Coturnix japonica) |
| Q42254465 | Comparative ability of TCDD to induce lipid peroxidation in rats, guinea pigs, and Syrian golden hamsters |
| Q36599268 | Comparative analysis of homology models of the AH receptor ligand binding domain: verification of structure-function predictions by site-directed mutagenesis of a nonfunctional receptor |
| Q36769360 | Comparative analysis of temporal and dose-dependent TCDD-elicited gene expression in human, mouse, and rat primary hepatocytes |
| Q35626784 | Comparative metabolomic and genomic analyses of TCDD-elicited metabolic disruption in mouse and rat liver |
| Q70504976 | Comparative studies on distribution and covalent tissue binding of 2,4,2',4'- and 3,4,3',4'-tetrachlorobiphenyl isomers in the rat |
| Q44107199 | Comparative toxicity of four chlorinated dibenzo-p-dioxins (CDDs) and their mixture. Part II: Structure-activity relationships with inhibition of hepatic phosphoenolpyruvate carboxykinase, pyruvate carboxylase, and gamma-glutamyl transpeptidase acti |
| Q33923892 | Comparison of TCDD-elicited genome-wide hepatic gene expression in Sprague-Dawley rats and C57BL/6 mice |
| Q50880675 | Comparison of polychlorinated dibenzodioxin levels with hepatic mixed-function oxidase induction in great blue herons. |
| Q46955199 | Comparison of the sex and subcellular distributions, catalytic and immunochemical reactivities of hepatic epoxide hydrolases in seven mammalian species |
| Q33896948 | Comparisons of differential gene expression elicited by TCDD, PCB126, βNF, or ICZ in mouse hepatoma Hepa1c1c7 cells and C57BL/6 mouse liver |
| Q34196453 | Competitive inhibition of the transcription of rabbit CYP1A1 gene by upstream stimulatory factor 1 (USF1). |
| Q36778762 | Complexities in understanding the nature of the dose-response for dioxins and related compounds |
| Q40497776 | Computational prediction of 7-ethoxyresorufin-O-diethylase (EROD) and luciferase (luc) inducing potency for 75 congeners of chloronaphthalene |
| Q44018833 | Conditional expression of a constitutively active aryl hydrocarbon receptor in MCF-7 human breast cancer cells |
| Q28767710 | Conformational analysis of environmental agents: use of X-ray crystallographic data to determine molecular reactivity |
| Q34564136 | Considerations for potency equivalent calculations in the Ah receptor-based CALUX bioassay: normalization of superinduction results for improved sample potency estimation |
| Q92060725 | Constitutive Aryl Hydrocarbon Receptor Signaling in Prostate Cancer Progression |
| Q39631404 | Constitutive activation of the aromatic hydrocarbon receptor |
| Q44583493 | Construction of reporter yeasts for mouse aryl hydrocarbon receptor ligand activity |
| Q28768660 | Contribution of organic particulates to respiratory cancer |
| Q37724777 | Contributions of the Ah receptor to bilirubin homeostasis and its antioxidative and atheroprotective functions |
| Q28360390 | Control of cytochrome P1-450 gene expression: analysis of a dioxin-responsive enhancer system |
| Q41197895 | Cooperative interaction between AhR.Arnt and Sp1 for the drug-inducible expression of CYP1A1 gene. |
| Q35956173 | Coordinate regulation of drug metabolism by xenobiotic nuclear receptors: UGTs acting together with CYPs and glucuronide transporters |
| Q55154999 | Copy Number Changes Identified Using Whole Exome Sequencing in Nonsyndromic Cleft Lip and Palate in a Honduran Population. |
| Q37604179 | Correlation between an in vitro and an in vivo measure of dioxin sensitivity in birds |
| Q40735460 | Correlation between the high expression of C/EBPbeta protein in F442A cells and their relative resistance to antiadipogenic action of TCDD in comparison to 3T3-L1 cells |
| Q36659973 | Cross-coupling of signal transduction pathways: the dioxin receptor mediates induction of cytochrome P-450IA1 expression via a protein kinase C-dependent mechanism |
| Q41646529 | Cross-talk between the aryl hydrocarbon receptor and hypoxia inducible factor signaling pathways. Demonstration of competition and compensation |
| Q91893459 | Crosstalk between hydroxytyrosol, a major olive oil phenol, and HIF-1 in MCF-7 breast cancer cells |
| Q53257699 | Curcumin, myrecen and cineol modulate the percentage of lymphocyte subsets altered by 2,3,7, 8-tetracholorodibenzo-p-dioxins (TCDD) in rats. |
| Q47693193 | Current state of yusho and prospects for therapeutic strategies |
| Q73335834 | Cytochrome P450 isoenzyme activities in cultured rat and mouse liver slices |
| Q47884757 | Cytochrome P4501A expression, chemical contaminants and histopathology in roach, goby and sturgeon and chemical contaminants in sediments from the Caspian Sea, Lake Balkhash and the Ily River Delta, Kazakhstan. |
| Q39143304 | Cytochrome P4501A1 expression in blubber biopsies of endangered false killer whales (Pseudorca crassidens) and nine other odontocete species from Hawai'i |
| Q47864441 | Cytochromes P450 in liver of the turtle Chrysemys picta picta and the induction and partial purification of CYP1A-like proteins |
| Q73039945 | Cytokines (IL-1beta and TNFalpha) in relation to biochemical and immunological effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in rats |
| Q84589454 | Cytotoxic response profiles of cultured rat hepatocytes to selected aromatic hydrocarbons |
| Q40772509 | Cytotoxicity and transcriptional activation of stress genes in human liver carcinoma cells (HepG2) exposed to cadmium chloride |
| Q28291880 | DNA Binding Specificities and Pairing Rules of the Ah Receptor, ARNT, and SIM Proteins |
| Q40874245 | Definition of a novel ligand binding domain of a nuclear bHLH receptor: co-localization of ligand and hsp90 binding activities within the regulable inactivation domain of the dioxin receptor |
| Q28539741 | Depletion of the aryl hydrocarbon receptor in MDA-MB-231 human breast cancer cells altered the expression of genes in key regulatory pathways of cancer |
| Q67913154 | Detection and characterization of Ah receptor in tissue and cells from human tonsils |
| Q46526112 | Detection of interaction of binding affinity of aromatic hydrocarbon receptor to the specific DNA by exonuclease protection mediated PCR assay |
| Q41668269 | Detection of the Ah receptor in rainbow trout: Use of 2-azido-3-[125I]iodo-7,8-dibromodibenzo-P-dioxmin in cell culture |
| Q38829494 | Determination of the CYP1A-inducing potential of single substances, mixtures and extracts of samples in the micro-EROD assay with H4IIE cells |
| Q38718595 | Development and validation of in vitro induction assays for toxic halogenated aromatic mixtures: a review |
| Q40029707 | Development of a human adipocyte model derived from human mesenchymal stem cells (hMSC) as a tool for toxicological studies on the action of TCDD. |
| Q40361490 | Development of a recombinant yeast assay to detect ah-receptor ligands |
| Q34856969 | Development of bioassays and approaches for the risk assessment of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds |
| Q33942473 | Development of the murine and human immune system: differential effects of immunotoxicants depend on time of exposure |
| Q61463240 | Development of toxic equivalency factors for PCB congeners and the assessment of TCDD and PCB mixtures in rainbow trout |
| Q52205520 | Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo. |
| Q49834562 | Dietary Broccoli Impacts Microbial Community Structure and Attenuates Chemically Induced Colitis in Mice in an Ah receptor dependent manner |
| Q42214268 | Dietary iron and 2,3,7,8-tetrachlorodibenzo-p-dioxin induced alterations in hepatic lipid peroxidation, glutathione content and body weight |
| Q73448662 | Dietary taurine potentiates polychlorinated biphenyl-induced hypercholesterolemia in rats* |
| Q28316093 | Differences in 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible CYP1A1 expression in human breast carcinoma cell lines involve altered trans-acting factors |
| Q33874371 | Differences in TCDD-elicited gene expression profiles in human HepG2, mouse Hepa1c1c7 and rat H4IIE hepatoma cells |
| Q89621809 | Differential Display Analysis of 2,3,7,8-Tetrachlorodibenzo-p-dioxin Identified Induction of Ras-related Nuclear Protein Binding Protein2 (RanBP2) Gene |
| Q60960962 | Differential Hepatic Gene Expression Profile of Male Fathead Minnows Exposed to Daily Varying Dose of Environmental Contaminants Individually and in Mixture |
| Q41570922 | Differential effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin, bis(tri-n-butyltin) oxide and cyclosporine on thymus histophysiology |
| Q30493724 | Differential gene regulation by the human and mouse aryl hydrocarbon receptor |
| Q45114106 | Differential induction of apoptosis in activated and resting T cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and its repercussion on T cell responsiveness |
| Q28140877 | Differential recruitment of coactivator RIP140 by Ah and estrogen receptors. Absence of a role for LXXLL motifs |
| Q35742037 | Differential tissue accumulation of 2,3,7,8-Tetrachlorinated dibenzo-p-dioxin in Arabidopsis thaliana affects plant chronology, lipid metabolism and seed yield |
| Q41687197 | Differential toxicities of TCDD in vivo among normal, c-src knockout, geldanamycin- and quercetin-treated mice |
| Q28396008 | Dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin) enhances triggered afterdepolarizations in rat ventricular myocytes |
| Q28367854 | Dioxin activates HIV-1 gene expression by an oxidative stress pathway requiring a functional cytochrome P450 CYP1A1 enzyme |
| Q24656224 | Dioxin cancer risk--example of hormesis? |
| Q34582073 | Dioxin exposure and porcine reproductive hormonal activity |
| Q28368202 | Dioxin induces localized, graded changes in chromatin structure: implications for Cyp1A1 gene transcription |
| Q52643341 | Dioxin pollution disrupts reproduction in male Japanese field mice. |
| Q36002965 | Dioxin silences gonadotropin expression in perinatal pups by inducing histone deacetylases: a new insight into the mechanism for the imprinting of sexual immaturity by dioxin |
| Q28343069 | Dioxin-dependent activation of murine Cyp1a-1 gene transcription requires protein kinase C-dependent phosphorylation |
| Q24650888 | Dioxin-induced CYP1A1 transcription in vivo: the aromatic hydrocarbon receptor mediates transactivation, enhancer-promoter communication, and changes in chromatin structure |
| Q36553707 | Dioxin-induced chloracne--reconstructing the cellular and molecular mechanisms of a classic environmental disease. |
| Q43606326 | Dioxin-inducible transactivation in a chromosomal setting. Analysis of the acidic domain of the Ah receptor |
| Q28330731 | Dioxin-inducible, Ah receptor-dependent transcription in vitro |
| Q36423404 | Dioxin-mediated tumor progression through activation of mitochondria-to-nucleus stress signaling |
| Q28767805 | Dioxin-receptor ligands in urban air and vehicle exhaust |
| Q34419662 | Dioxin: a review of its environmental effects and its aryl hydrocarbon receptor biology |
| Q32172238 | Dioxinlike components in incinerator fly ash: a comparison between chemical analysis data and results from a cell culture bioassay |
| Q28768742 | Dioxinlike properties of a trichloroethylene combustion-generated aerosol |
| Q28287699 | Dioxins, the aryl hydrocarbon receptor and the central regulation of energy balance |
| Q37255560 | Dioxins: diagnostic and prognostic challenges arising from complex mechanisms |
| Q36490903 | Direct, continuous monitoring of air pollution by transgenic sensor mice responsive to halogenated and polycyclic aromatic hydrocarbons |
| Q35329434 | Discovery and biological characterization of 1-(1H-indol-3-yl)-9H-pyrido[3,4-b]indole as an aryl hydrocarbon receptor activator generated by photoactivation of tryptophan by sunlight |
| Q70369247 | Disposition of toxic PCB congeners in snapping turtle eggs: expressed as toxic equivalents of TCDD |
| Q35021811 | Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse |
| Q38471284 | Distribution and inducibility of a P450I activity in cellular components of the avian immune system |
| Q42945905 | Distribution of 14C-2,3,7,8-tetrachlorodibenzo-p-dioxin to the brain and peripheral tissues of fetal rats and its comparison with adults |
| Q52541388 | Distribution of mRNAs encoding the arylhydrocarbon receptor, arylhydrocarbon receptor nuclear translocator, and arylhydrocarbon receptor nuclear translocator-2 in the rat brain and brainstem. |
| Q59956622 | Diversity as Opportunity: Insights from 600 Million Years of AHR Evolution |
| Q40189612 | Domestication of chemistry by design of safer chemicals: structure-activity relationships |
| Q41815120 | Dose-dependent acinar induction of cytochromes P450 in rat liver. Evidence for a differential mechanism of induction of P450IA1 by β-naphthoflavone and dioxin |
| Q36890799 | Down-regulation of major histocompatibility complex Q1b gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q36664441 | Down-regulation of nuclear aryl hydrocarbon receptor DNA-binding and transactivation functions: requirement for a labile or inducible factor |
| Q45910530 | Drug metabolism. Growth signal pathways. |
| Q28372455 | ECC-1 human endometrial cells as a model system to study dioxin disruption of steroid hormone function |
| Q42350421 | EWS-FLI1 impairs aryl hydrocarbon receptor activation by blocking tryptophan breakdown via the kynurenine pathway |
| Q42278011 | Early effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on rat thymocytes in vitro |
| Q37118497 | Early experiences matter: a review of the effects of prenatal environment on offspring characteristics in poultry |
| Q40937295 | Ecological risk assessment for mink and short-tailed shrew exposed to PCBs, dioxins, and furans in the Housatonic River area |
| Q68031033 | Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on benzo(a)pyrene hydroxylase activity in embryos of the Japanese medaka (Oryzias latipes) |
| Q53527760 | Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on testicular spermatogenesis-related panels and serum sex hormone levels in rats. |
| Q38517278 | Effect of TCDD on corpus cavernosum histology and smooth muscle physiology. |
| Q73065728 | Effect of a single or repeated dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on T cell subpopulations in the Long-Evans rat |
| Q42726093 | Effect of aflatoxin B1 on nuclear receptors PXR, CAR, and AhR and their target cytochromes P450 mRNA expression in primary cultures of human hepatocytes. |
| Q38014817 | Effect of cis-platinum on heme, drug, and steroid metabolism pathways: possible involvement in nephrotoxicity and infertility |
| Q47711963 | Effect of curcumin on the aryl hydrocarbon receptor and cytochrome P450 1A1 in MCF-7 human breast carcinoma cells |
| Q69961136 | Effect of hexachlorobiphenyl on vitamin A homeostasis in the rat |
| Q38306614 | Effect of in vitro administered 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on DNA-binding activities of nuclear transcription factors in NIH-3T3 mouse fibroblasts |
| Q43132141 | Effect of piratoxin II and acutohaemolysin phospholipase (PLA2) proteins on myristic fatty acid--an ONIOM and DFT study |
| Q44461834 | Effects of 3,3',4,4',5-pentachlorobiphenyl, a coplanar polychlorinated biphenyl congener, on cultured neonatal mouse testis |
| Q46411873 | Effects of PCB 126 on primary immune organs and thymocyte apoptosis in chicken embryos |
| Q33647833 | Effects of TCDD on the expression of nuclear encoded mitochondrial genes |
| Q43946649 | Effects of benzo[a]pyrene exposure on a fish population resistant to the toxic effects of dioxin-like compounds |
| Q48241013 | Effects of chlorinated organics on intermediates in the heme pathway and on uroporphyrinogen decarboxylase |
| Q52455189 | Effects of commercial chlorophenolate, 2,3,7,8-TCDD, and pure phenoxyacetic acids on hepatic peroxisome proliferation, xenobiotic metabolism and sister chromatid exchange in the rat. |
| Q44384660 | Effects of dietary carbohydrate and myo-inositol on metabolic changes in rats fed 1,1,1-trichloro-2,2-bis (p-chlorophenyl) ethane (DDT). |
| Q43625116 | Effects of dioxin, an environmental pollutant, on mouse blastocyst development and apoptosis |
| Q50856013 | Effects of environmentally relevant concentrations of 2,3,7,8-TCDD on domestic chicken immune function and CYP450 activity: F1 generation and egg injection studies. |
| Q77598948 | Effects of in ovo exposure to 2,3,7,8-TCDD on F1 generation adult chickens (Gallus gallus) |
| Q28646019 | Effects of in vivo-administered 2,3,7,8-tetrachlorodibenzo-p-dioxin on receptor binding of epidermal growth factor in the hepatic plasma membrane of rat, guinea pig, mouse, and hamster |
| Q37351621 | Effects of organochlorine chemicals on the reproductive outcome of humans who consumed contaminated Great Lakes fish: an epidemiologic consideration |
| Q43100105 | Effects of polycyclic aromatic hydrocarbons in northern bobwhite quail (Colinus virginianus). |
| Q39281290 | Effects of selected phytoestrogens and their mixtures on the function of the thyroid hormone and the aryl hydrocarbon receptor |
| Q43908005 | Effects of src-deficiency on the expression of in vivo toxicity of TCDD in a strain of c-src knockout mice procured through six generations of backcrossings to C57BL/6 mice |
| Q35035942 | Effects of structure on binding to the 2,3,7,8-TCDD receptor protein and AHH induction--halogenated biphenyls |
| Q52389895 | Effects of the mechanism of receptor-mediated gene expression on the shape of the dose-response curve. |
| Q41367917 | Effects of thyroidectomy on the Ah receptor and enzyme inducibility by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat liver |
| Q44063481 | Electronic elasticity-toxicity relationships for polychlorinated dibenzo-p-dioxin congeners |
| Q74505313 | Elimination kinetics and toxicity of 2,3,7,8-tetrachlorothianthren, a thio analogue of 2,3,7,8-TCDD |
| Q87843580 | Embryonic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs prey capture by zebrafish larvae |
| Q84696556 | Embryotoxic potency of 2,4,5-trichlorophenoxyacetic acid on sea urchin eggs: Association with calcium homoeostasis |
| Q37084259 | Endocrine disruptors and falling sperm counts: lessons learned or not! |
| Q43733538 | Enhanced activation-induced cell death as a mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immunotoxicity in peripheral T cells. |
| Q40200353 | Enhancement of xenobiotic elimination: role of intestinal excretion |
| Q26747621 | Environmental Ligands of the Aryl Hydrocarbon Receptor and Their Effects in Models of Adult Liver Progenitor Cells |
| Q34638179 | Environmental effects and aquatic organisms: investigations of molecular mechanisms of carcinogenesis |
| Q40118443 | Environmental reactions to chemical, physical, and biologic agents |
| Q34843146 | Environmental toxicology of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans |
| Q41480836 | Environmental toxins and endometriosis |
| Q39847955 | Enzymatic activation of chemicals to toxic metabolites. |
| Q82862617 | Estrogen receptor and aromatic hydrocarbon receptor in the primate ovary |
| Q37197814 | Estrogen receptor α can selectively repress dioxin receptor-mediated gene expression by targeting DNA methylation |
| Q43617190 | Estrogenic and antiestrogenic effect of in vitro treatment of follicular cells with 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q46824032 | Estrogenic status modulates aryl hydrocarbon receptor--mediated hepatic gene expression and carcinogenicity. |
| Q73574526 | Estrous cycle-dependent changes in the expression of aromatic hydrocarbon receptor (AHR) and AHR-nuclear translocator (ARNT) mRNAs in the rat ovary and liver |
| Q42746968 | Evaluation of chlorinated benz[a]anthracene on hepatic toxicity in rats and mutagenic activity in Salmonella typhimurium. |
| Q46646391 | Evidence for a second pathway in the action mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Significance of Ah-receptor mediated activation of protein kinase under cell-free conditions |
| Q24812042 | Evidence that GABAergic neurons in the preoptic area of the rat brain are targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin during development |
| Q28392826 | Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor |
| Q70195814 | Examination and rapid analysis of hepatic cytosolic receptors for 2,3,7,8-tetrachlorodibenzo-p-dioxin using gel-permeation high performance liquid chromatography |
| Q39829778 | Exposure to toxic agents: the heme biosynthetic pathway and hemoproteins as indicator |
| Q70887445 | Expression of 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P4501A1 in human splenic lymphocyte cultures |
| Q40908395 | Expression of E16/CD98LC/hLAT1 is responsive to 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q48056644 | Expression of aryl hydrocarbon receptor (AhR) and aryl hydrocarbon receptor nuclear translocator (Arnt) in adult rabbits known to be non-responsive to cytochrome P-450 1A1 (CYP1A1) inducers |
| Q43815506 | Expression of human and mouse genes encoding polkappa: testis-specific developmental regulation and AhR-dependent inducible transcription |
| Q41157876 | Expression of the aryl hydrocarbon receptor is regulated by serum and mitogenic growth factors in murine 3T3 fibroblasts. |
| Q34835746 | Expression of xenobiotic-metabolizing enzymes in cultured rat tracheal epithelial cells |
| Q74062826 | Flavones and flavonols at dietary levels inhibit a transformation of aryl hydrocarbon receptor induced by dioxin |
| Q28586157 | For dioxin-induced birth defects, mouse or human CYP1A2 in maternal liver protects whereas mouse CYP1A1 and CYP1B1 are inconsequential |
| Q35035551 | Formation, occurrence and analysis of polychlorinated dibenzofurans, dioxins and related compounds |
| Q40152462 | From dioxin to drug lead--the development of 2,3,7,8-tetrachlorophenothiazine |
| Q46286517 | From the Cover: Development and Application of a Dual Rat and Human AHR Activation Assay |
| Q40656399 | Functional alterations in CD11b+Gr-1+ cells in mice injected with allogeneic tumor cells and treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q28504815 | Functional analysis of activation and repression domains of the rainbow trout aryl hydrocarbon receptor nuclear translocator (rtARNT) protein isoforms |
| Q28335996 | Functional analysis of the transcriptional promoter for the CYP1A1 gene |
| Q28609386 | Functional role of AhR in the expression of toxic effects by TCDD |
| Q72412010 | Gastrointestinal uptake and vascular transport of 2,4'-dichlorobiphenyl |
| Q28727353 | Gender differences in transcriptional signature of developing rat testes and ovaries following embryonic exposure to 2,3,7,8-TCDD |
| Q35470109 | Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation |
| Q34468175 | Genetic differences in lethality of newborn mice treated in utero with coplanar versus non-coplanar hexabromobiphenyl |
| Q33684503 | Genome-wide computational analysis of dioxin response element location and distribution in the human, mouse, and rat genomes |
| Q53958801 | Gestational and lactational exposure to TCDD or coplanar PCBs alters adult expression of saccharin preference behavior in female rats. |
| Q37692340 | Gestational exposure of Ahr and Arnt hypomorphs to dioxin rescues vascular development |
| Q36764382 | Glutathione S-transferases: gene structure and regulation of expression |
| Q34435865 | Glycine N-methyltransferase is an example of functional diversity. Role as a polycyclic aromatic hydrocarbon-binding receptor |
| Q69416110 | Goitre and wasting induced in hamsters by hexachlorobenzene |
| Q37255104 | Great Lakes embryo mortality, edema, and deformities syndrome (GLEMEDS) in colonial fish-eating birds: similarity to chick-edema disease |
| Q41586074 | Growth stimulation of primary rat hepatocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q68255486 | H4IIE rat hepatoma cell bioassay-derived 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents in colonial fish-eating waterbird eggs from the Great Lakes |
| Q40091673 | HDAC1 bound to the Cyp1a1 promoter blocks histone acetylation associated with Ah receptor-mediated trans-activation |
| Q71876206 | Halogenated aromatic hydrocarbon-induced suppression of the plaque-forming cell response in B6C3F1 splenocytes cultured with allogenic mouse serum: Ah receptor structure activity relationships |
| Q48776795 | Halogenated aromatic hydrocarbon-mediated porphyrin accumulation and induction of cytochrome P4501A in chicken embryo hepatocytes |
| Q68257116 | Halogenated aryl hydrocarbon-induced suppression of the in vitro plaque-forming cell response to sheep red blood cells is not dependent on the Ah receptor |
| Q34940845 | Hazard and risk assessment of chemical mixtures using the toxic equivalency factor approach |
| Q34563180 | Hazard characterisation of chemicals in food and diet. dose response, mechanisms and extrapolation issues |
| Q50201678 | Health-risk estimates for 2,3,7,8-tetrachloro-dibenzodioxin: an overview |
| Q37486608 | Heart as a target organ in 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity: decreased beta-adrenergic responsiveness and evidence of increased intracellular calcium |
| Q73065734 | Hepatic Ah receptor binding affinity for 2,3,7,8-tetrachlorodibenzo-p-dioxin: similarity between beagle dog and cynomolgus monkey |
| Q89008886 | Hepatocyte-Specific Deletion of TIPARP, a Negative Regulator of the Aryl Hydrocarbon Receptor, Is Sufficient to Increase Sensitivity to Dioxin-Induced Wasting Syndrome |
| Q42947878 | Highly purified hexachlorobenzene induces cytochrome P4501A in primary cultures of chicken embryo hepatocytes |
| Q36282906 | Homocitrullination Is a Novel Histone H1 Epigenetic Mark Dependent on Aryl Hydrocarbon Receptor Recruitment of Carbamoyl Phosphate Synthase 1. |
| Q34467146 | How can chemical compounds alter human fertility? |
| Q33911330 | Human risk assessment and TEFs |
| Q68459648 | Hypothalamic site of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) |
| Q58765321 | Identification of a dioxin-responsive oxylipin signature in roots of date palm: involvement of a 9-hydroperoxide fatty acid reductase, caleosin/peroxygenase PdPXG2 |
| Q42554179 | Identification of a novel cis-acting negative regulatory element affecting expression of the CYP1A1 gene in rat epidermal cells |
| Q24609846 | Identification of a novel mechanism of regulation of Ah (dioxin) receptor function |
| Q42552290 | Identification of c-Src as the integral component of the cytosolic Ah receptor complex, transducing the signal of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) through the protein phosphorylation pathway |
| Q40108569 | Identification of novel dioxin-responsive genes by representational difference analysis |
| Q34385994 | Identification of the Aryl Hydrocarbon Receptor Target Gene TiPARP as a Mediator of Suppression of Hepatic Gluconeogenesis by 2,3,7,8-Tetrachlorodibenzo-p-dioxin and of Nicotinamide as a Corrective Agent for This Effect |
| Q28589085 | Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor |
| Q78017654 | Immunochemical approaches to studies of CYP1A localization and induction by xenobiotics in fish |
| Q64765384 | Immunochemical quantitation of cytochrome P-450 isozymes and epoxide hydrolase in liver microsomes from polychlorinated or polybrominated biphenyl-treated rats. A study of structure-activity relationships |
| Q34830969 | Immunological effects of chlorinated dibenzo-p-dioxins |
| Q34832366 | Immunoresponsiveness in endometriosis: implications of estrogenic toxicants |
| Q34154137 | Immunotoxicology: past, present, and future |
| Q35985194 | Impact of environmental exposures on ovarian function and role of xenobiotic metabolism during ovotoxicity |
| Q26343882 | Impact of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls on human and environmental health, with special emphasis on application of the toxic equivalency factor concept |
| Q36358349 | Impaired glucose and lipid metabolism in ageing aryl hydrocarbon receptor deficient mice |
| Q34636543 | Implications for risk assessment of suggested nongenotoxic mechanisms of chemical carcinogenesis |
| Q70194259 | Importance of the route of administration for genetic differences in benzo[a]pyrene-induced in utero toxicity and teratogenicity |
| Q36920142 | In situ protein-DNA interactions at a dioxin-responsive enhancer associated with the cytochrome P1-450 gene |
| Q43832576 | In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin decreases serotonin-immunoreactive neurons in raphe nuclei of male mouse offspring |
| Q34136666 | In utero exposure to dioxin causes neocortical dysgenesis through the actions of p27Kip1 |
| Q36255259 | In vitro System for Assessing Dioxin Absorption by Intestinal Epithelial Cells and for Preventing this Absorption by Food Substances |
| Q24561542 | In vitro analysis of Ah receptor domains involved in ligand-activated DNA recognition |
| Q43672573 | In vitro response of fish and mammalian cells to complex mixtures of polychlorinated naphthalenes, polychlorinated biphenyls, and polycyclic aromatic hydrocarbons |
| Q69819874 | In vivo and in vitro interactions of TCDD and other ligands of the Ah-receptor: effect on embryonic and fetal tissues |
| Q31007679 | In vivo dioxin favors interleukin-22 production by human CD4+ T cells in an aryl hydrocarbon receptor (AhR)-dependent manner |
| Q42514790 | In vivo up-regulation of aryl hydrocarbon receptor expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in a dioxin-resistant rat model |
| Q33239768 | In vivo-in vitro toxicogenomic comparison of TCDD-elicited gene expression in Hepa1c1c7 mouse hepatoma cells and C57BL/6 hepatic tissue |
| Q40636933 | Increased arylhydrocarbon receptor expression offers a potential therapeutic target for pancreatic cancer |
| Q36077694 | Indole and Tryptophan Metabolism: Endogenous and Dietary Routes to Ah Receptor Activation |
| Q28359811 | Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer |
| Q70168041 | Induction of 7-ethoxycoumarin O-deethylase activity in cultured human epithelial cells by 2,3,7,8-tetrachlorodibenzo-P-dioxin (TCDD): Evidence for TCDD receptor |
| Q23923467 | Induction of P-450 in workers exposed to dioxin |
| Q42528121 | Induction of cytochrome P-450-dependent monooxygenase systems in embryos and eleutheroembryos of the killfish Fundulus heteroclitus |
| Q40660197 | Induction of cytochrome P4501A and endocrine disrupting effects of school incinerator residues. |
| Q72164972 | Induction of cytochrome P4501A by smoking or omeprazole in comparison with UDP-glucuronosyltransferase in biopsies of human duodenal mucosa |
| Q28378843 | Induction of cytochrome P4501A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin or indolo(3,2-b)carbazole is associated with oxidative DNA damage |
| Q41676803 | Induction of drug-metabolizing enzymes by dioxin |
| Q37831726 | Induction of drug-metabolizing enzymes by xenobiotics |
| Q39733543 | Induction of drug-metabolizing enzymes: mechanisms and consequences |
| Q67465696 | Induction of hepatic CYP1A in male F344/NCr rats by dietary exposure to Aroclor 1254: examination of immunochemical, RNA, catalytic, and pharmacokinetic endpoints |
| Q70304773 | Induction of immunotoxicity in mice by polyhalogenated biphenyls |
| Q52452194 | Induction of lipid peroxidation by hexachlorocyclohexane, dieldrin, TCDD, carbon tetrachloride, and hexachlorobenzene in rats. |
| Q43513412 | Induction of lung lesions in female rats following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q23919661 | Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap n collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) |
| Q44038383 | Induction of oxidative stress in the tissues of rats after chronic exposure to TCDD, 2,3,4,7,8-pentachlorodibenzofuran, and 3,3',4,4',5-pentachlorobiphenyl |
| Q28384931 | Induction of oxidative stress responses by dioxin and other ligands of the aryl hydrocarbon receptor |
| Q77386688 | Induction of pulmonary CYP1A1 by nicotine |
| Q43774710 | Induction of rat liver cytochrome P450 isoenzymes CYP 1A and CYP 2B by different fungicides, nitrofurans, and quercetin |
| Q77994126 | Inductive and inhibitory effects of non-ortho-substituted polychlorinated biphenyls on estrogen metabolism and human cytochromes P450 1A1 and 1B1 |
| Q51013378 | Influence of AHRR Pro189Ala polymorphism on kidney functions. |
| Q23919671 | Influence of light on aryl hydrocarbon receptor signaling and consequences in drug metabolism, physiology and disease |
| Q73305434 | Inhibition of 3,3',4,4',5-pentachlorobiphenyl-induced fetal cleft palate and immunotoxicity in C57BL/6 mice by 2,2',4,4',5,5'-hexachlorobiphenyl |
| Q71876202 | Inhibition of DNA synthesis in primary cultures of adult rat hepatocytes by benzo[a]pyrene and related aromatic hydrocarbons: Role of Ah receptor-dependent events |
| Q73438445 | Inhibition of LPS-induced splenocyte proliferation by ortho-substituted polychlorinated biphenyl congeners |
| Q54406587 | Inhibition of TCDD-induced lipid peroxidation, glutathione peroxidase activity and toxicity by BHA and glutathione. |
| Q36873039 | Inhibition of constitutive aryl hydrocarbon receptor (AhR) signaling attenuates androgen independent signaling and growth in (C4-2) prostate cancer cells |
| Q73889909 | Inhibition of the transcription of CYP1A1 gene by the upstream stimulatory factor 1 in rabbits. Competitive binding of USF1 with AhR.Arnt complex |
| Q28327185 | Integrated approach for evaluating species and interindividual differences in responsiveness to dioxins and structural analogs |
| Q33962508 | Integration of genome-wide computation DRE search, AhR ChIP-chip and gene expression analyses of TCDD-elicited responses in the mouse liver |
| Q44593859 | Interaction of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) with induced adipocyte differentiation in mouse embryonic fibroblasts (MEFs) involves tyrosine kinase c-Src |
| Q69974382 | Interaction of 3,4,3',4'-tetrachlorobiphenyl metabolites formed by cytochrome P-450 in vitro with rat erythrocytes |
| Q73946886 | Interactions between aryl hydrocarbon receptor (AhR) and hypoxia signaling pathways |
| Q22010224 | Interactions of nuclear receptor coactivator/corepressor proteins with the aryl hydrocarbon receptor complex |
| Q36801801 | Interference of endocrine disrupting chemicals with aromatase CYP19 expression or activity, and consequences for reproduction of teleost fish |
| Q34072962 | Interpretation of studies on the developmental reproductive toxicology of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male offspring |
| Q47143523 | Interrelated Roles for the Aryl Hydrocarbon Receptor and Hypoxia Inducible Factor-1α in the Immune Response to Infection. |
| Q42542131 | Interruption of estradiol signal transduction by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) through disruption of the protein phosphorylation pathway in adipose tissues from immature and mature female rats |
| Q38011036 | Interspecies comparisons in toxicology: the utility and futility of plasma concentrations of the test substance |
| Q34124220 | Intrinsic function of the aryl hydrocarbon (dioxin) receptor as a key factor in female reproduction |
| Q28391047 | Introducing the "TCDD-inducible AhR-Nrf2 gene battery" |
| Q72918470 | Isomer-specific analysis and toxic evaluation of polychlorinated biphenyls in striped dolphins affected by an epizootic in the western Mediterranean sea |
| Q70210930 | Key enzymes of gluconeogenesis are dose-dependently reduced in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treated rats |
| Q37231015 | Knockdown of aberrantly upregulated aryl hydrocarbon receptor reduces tumor growth and metastasis of MDA-MB-231 human breast cancer cell line |
| Q70339875 | Lack of correlation between formation of reactive metabolites and thymic atrophy caused by 3, 4, 3', 4'-tetrachlorobiphenyl in C57BL/6N mice |
| Q37419695 | Lack of ligand-selective binding of the aryl hydrocarbon receptor to putative DNA binding sites regulating expression of Bax and paraoxonase 1 genes |
| Q44769181 | Lead-induced cytotoxicity and transcriptional activation of stress genes in human liver carcinoma (HepG2) cells |
| Q28221101 | Ligand binding and activation of the Ah receptor |
| Q24314469 | Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo |
| Q36528871 | Ligand-dependent interactions of the Ah receptor with coactivators in a mammalian two-hybrid assay |
| Q24606019 | Ligand-dependent recruitment of the Arnt coregulator determines DNA recognition by the dioxin receptor |
| Q37764998 | Long-term carcinogenesis studies on 2,3,7,8-tetrachlorodibenzo-p-dioxin and hexachlorodibenzo-p-dioxins |
| Q44900973 | Long-term effects of commercial and congeneric polychlorinated biphenyls on ethane production and malondialdehyde levels, indicators of in vivo lipid peroxidation |
| Q35860542 | Loss of the Mono-ADP-ribosyltransferase, Tiparp, Increases Sensitivity to Dioxin-induced Steatohepatitis and Lethality |
| Q34710039 | Low concentration of a dioxin (2, 3, 7, 8 TCDD) affects the glycosidases and Acid phosphatase activity in mice hepatocytes |
| Q54449975 | Low rate of NADPH/ADP-iron dependent lipid peroxidation in hepatic microsomes of DBA/2 mice. |
| Q54977289 | Lymphocyte-specific protein tyrosine kinase (LCK) is involved in the aryl hydrocarbon receptor (AHR)-mediated impairment of immunoglobulin secretion in human primary B cells. |
| Q33804702 | Malignant transformation of mammary epithelial cells by ectopic overexpression of the aryl hydrocarbon receptor |
| Q28341109 | Marked increases in hepatic NAD(P)H:oxidoreductase gene transcription and mRNA levels correlated with a mouse chromosome 7 deletion |
| Q38337429 | Mechanism of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonists: Characterization of 6-[125I]methyl-8-iodo-1, 3-dichlorodibenzofuran-Ah receptor complexes |
| Q34064165 | Mechanism of action of estrogens and selective estrogen receptor modulators |
| Q35034263 | Mechanism of action of toxic halogenated aromatics |
| Q37030412 | Mechanism of dioxin action: Ah receptor-mediated increase in promoter accessibility in vivo |
| Q28378613 | Mechanism of dioxin action: receptor-enhancer interactions in intact cells |
| Q34564142 | Mechanism-based common reactivity pattern (COREPA) modelling of aryl hydrocarbon receptor binding affinity |
| Q38451487 | Mechanisms of TCDD-induced abnormalities and embryo lethality in white leghorn chickens |
| Q28583725 | Mechanisms of exocrine pancreatic toxicity induced by oral treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Harlan Sprague-Dawley Rats |
| Q46102619 | Mechanisms of gender-specific TCDD-induced toxicity in guinea pig adipose tissue |
| Q35671175 | Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast cancer cells |
| Q42463018 | Mechanisms of ligand-induced aryl hydrocarbon receptor-mediated biochemical and toxic responses |
| Q35035487 | Mechanisms of the biological effects of PCBs, polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in experimental animals |
| Q40155146 | Mechanisms of toxic injury |
| Q51487450 | Meeting the European Commission performance criteria for the use of triple quadrupole GC-MS/MS as a confirmatory method for PCDD/Fs and dl-PCBs in food and feed samples. |
| Q73018742 | Metabolic degradation, inducing potency, and metabolites of fluorinated and chlorinated-fluorinated dibenzodioxins and dibenzofurans |
| Q41528811 | Methods for predicting carcinogenic hazards: new opportunities coming from recent developments in molecular oncology and SAR studies. |
| Q40102359 | Methoxychlor suppresses the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible CYP1A1 expression in murine Hepa-1c1c7 cells |
| Q35196055 | Microbial dechlorination of historically present and freshly spiked chlorinated dioxins and diversity of dioxin-dechlorinating populations |
| Q69771129 | Microcontaminants and reproductive impairment of the Forster's tern on Green Bay, Lake Michigan--1983 |
| Q33844883 | Mitochondrial P450-dependent arachidonic acid metabolism by TCDD-induced hepatic CYP1A5; conversion of EETs to DHETs by mitochondrial soluble epoxide hydrolase |
| Q44193406 | Mitochondrial reactive oxygen production is dependent on the aromatic hydrocarbon receptor |
| Q36466007 | Modeling drug- and chemical-induced hepatotoxicity with systems biology approaches. |
| Q53474841 | Modulating effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on skin carcinogenesis initiated by the weak inducer 7,12-dimethylbenz(a)anthracene. |
| Q47754454 | Modulating effects of thyroid state on the induction of biotransformation enzymes by 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q33851590 | Modulation of 3-methylcholanthrene toxicity in cultured neoplastic keratinocytes by glucocorticoids and retinoids is not accounted for by macromolecular adduct formation |
| Q52680458 | Modulation of aryl hydrocarbon receptor transactivation by carbaryl, a nonconventional ligand. |
| Q82862696 | Modulation of growth axis gene expression by in utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the weaning Holtzman rat |
| Q45094553 | Modulation of liver intracellular C3 in mice by 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q52528757 | Modulation of ovarian follicle maturation and effects on apoptotic cell death in Holtzman rats exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in utero and lactationally. |
| Q51143513 | Molecular Polarization Potential as a Molecular Descriptor to Predict Biological Activity of Dioxins and Dibenzofurans. |
| Q34232300 | Molecular biology of the Ah receptor and its role in carcinogenesis |
| Q28589578 | Molecular characterization of the murine Hif-1 alpha locus |
| Q73739568 | Molecular cloning and expression analysis of the aryl hydrocarbon receptor of Xenopus laevis |
| Q42552028 | Molecular cloning and expression of two novel avian cytochrome P450 1A enzymes induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q33724237 | Molecular evolution of two vertebrate aryl hydrocarbon (dioxin) receptors (AHR1 and AHR2) and the PAS family |
| Q37613529 | Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment |
| Q28378735 | Molecular mechanism of inhibition of estrogen-induced cathepsin D gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in MCF-7 cells |
| Q36473503 | Molecular mechanisms of 2,3,7,8-tetrachlorodibenzo-p-dioxin cardiovascular embryotoxicity |
| Q88046085 | Molecular modeling of the AhR structure and interactions can shed light on ligand-dependent activation and transformation mechanisms |
| Q50773886 | Monitoring biological effects of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in great blue heron chicks (Ardea herodias) in British Columbia. |
| Q33450608 | Morphologic lesions and acute toxicity in rainbow trout (Salmo gairdneri) treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q53029711 | Morphological and histochemical effects of 2,3,7,8-tetrachlorodibenzo-p dioxin (TCDD) on marmoset (Callithrix jacchus) testes. |
| Q41555123 | Mouse Hepa 1c1c7 hepatoma cells produce complement component C3; 2,3,7,8-tetrachlorodibenzo-p-dioxin fails to modulate this capacity |
| Q35034380 | Multifunctional receptor model for dioxin and related compound toxic action: possible thyroid hormone-responsive effector-linked site |
| Q34094520 | Mutagenicity of 3-chlorodibenzofuran and its metabolic activation |
| Q43639957 | Mutagenicity of TCDD in Big Blue transgenic rats |
| Q33720228 | NAD+ loss, a new player in AhR biology: prevention of thymus atrophy and hepatosteatosis by NAD+ repletion |
| Q35748659 | Naturally occurring marine brominated indoles are aryl hydrocarbon receptor ligands/agonists |
| Q35686667 | New aryl hydrocarbon receptor homology model targeted to improve docking reliability |
| Q28391958 | Non-additive hepatic gene expression elicited by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) co-treatment in C57BL/6 mice |
| Q36532748 | Nuclear pyruvate kinase M2 complex serves as a transcriptional coactivator of arylhydrocarbon receptor |
| Q40860785 | Nuclear receptor coactivator SRC-1 interacts with the Q-rich subdomain of the AhR and modulates its transactivation potential. |
| Q28327013 | Nucleoside triphosphates promote the transformation of Ah receptor to its DNA-binding form |
| Q53490734 | Omeprazole, cytochrome P450, and chemical carcinogenesis |
| Q37558012 | On the mechanisms of induction of cancer-protective enzymes: a unifying proposal |
| Q35195331 | On the significance of the role of cellular stress response reactions in the toxic actions of dioxin |
| Q70189583 | Ontogeny of the cytosolic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver, lung, and thymus |
| Q40957710 | Organochlorine compounds and estrogen-related cancers in women |
| Q40976570 | Organochlorine compounds in relation to breast cancer, endometrial cancer, and endometriosis: an assessment of the biological and epidemiological evidence |
| Q39665059 | Overdose toxicity studies versus threshold: elements of biology must be incorporated into risk assessment |
| Q23919654 | Overview of AHR functional domains and the classical AHR signaling pathway: induction of drug-metabolizing enzymes |
| Q37703439 | PCB153-elicited hepatic responses in the immature, ovariectomized C57BL/6 mice: comparative toxicogenomic effects of dioxin and non-dioxin-like ligands |
| Q24669769 | PCBs: structure-function relationships and mechanism of action |
| Q52176492 | Panax ginseng protects the testis against 2,3,7, 8-tetrachlorodibenzo-p-dioxin induced testicular damage in guinea pigs. |
| Q73459521 | Pathogenesis of cleft palate in mouse embryos exposed to 2,3,7, 8-tetrachlorodibenzo-p-dioxin (TCDD) |
| Q34059850 | Pathology and toxicology of beluga whales from the St. Lawrence Estuary, Quebec, Canada. Past, present and future |
| Q53495401 | Pathology reevaluation of the Kociba et al. (1978) bioassay of 2,3,7,8-TCDD: implications for risk assessment. |
| Q42429253 | Persistence of decreased T-helper cell function in industrial workers 20 years after exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q33803848 | Persistent binding of ligands to the aryl hydrocarbon receptor |
| Q35032650 | Perturbations of the immune system by xenobiotics |
| Q42555939 | Phenobarbital induction of CYP1A1 gene expression in a primary culture of rainbow trout hepatocytes. |
| Q35172859 | Photocontact dermatitis and chloracne: two major occupational and environmental skin diseases induced by different actions of halogenated chemicals |
| Q43614929 | Physiological modeling of a proposed mechanism of enzyme induction by TCDD. |
| Q35031091 | Polybrominated dibenzo-p-dioxins and dibenzofurans: literature review and health assessment |
| Q36873760 | Polybrominated dibenzo-p-dioxins, dibenzofurans, and biphenyls: inclusion in the toxicity equivalency factor concept for dioxin-like compounds |
| Q34245440 | Polychlorinated Biphenyls (PCBs) and Polybrominated Biphenyls (PBBs): Biochemistry, Toxicology, and Mechanism of Action |
| Q67488427 | Polychlorinated and polybrominated biphenyl congeners and retinoid levels in rat tissues: Structure-activity relationships |
| Q37830191 | Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). |
| Q29615426 | Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment |
| Q71557952 | Polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents in eggs of double-crested cormorants from a colony near Green Bay, Wisconsin, USA |
| Q70407921 | Polychlorinated biphenyls and polychlorinated dibenzofurans in the tissues of patients with yusho or yu-chen: total toxicity |
| Q34815832 | Polymorphisms in the human AH receptor |
| Q41925049 | Polypeptide hormone degradation and receptor regulation are coupled to ligand internalization. A direct biochemical and morphologic demonstration |
| Q52282476 | Possible effect of neonatal polybrominated biphenyl exposure on the developmental abilities of children |
| Q34057926 | Possible mechanisms of action of environmental contaminants on St. Lawrence beluga whales (Delphinapterus leucas) |
| Q51426758 | Prediction of subcooled vapor pressures (log PL) of 399 polychlorinated trans-azoxybenzenes by using the QSPR and ANN approach. |
| Q24672015 | Prenatal immunotoxicant exposure and postnatal autoimmune disease |
| Q37312637 | Pretreatment with TCDD exacerbates liver injury from Concanavalin A: critical role for NK cells |
| Q46223017 | Pretreatment with mixed-function oxidase inducers increases the sensitivity of the hepatocyte/DNA repair assay |
| Q71819077 | Production and Characterization of Monoclonal Antibodies Directed against theAhReceptor |
| Q57409037 | Production of a novel recombinant cell line for use as a bioassay system for detection of 2,3,7,8-tetrachlorodibenzo-P-dioxin-like chemicals |
| Q45094699 | Production of complement component C3 in vivo following 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure |
| Q43639093 | Production of superoxide anion, lipid peroxidation and DNA damage in the hepatic and brain tissues of rats after subchronic exposure to mixtures of TCDD and its congeners |
| Q39142602 | Promoter analysis of two aromatase genes in the serial-sex changing gobiid fish, Trimma okinawae |
| Q33632061 | Proteomic analysis of human keratinocyte response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure |
| Q37077861 | Pulmonary lesions in female Harlan Sprague-Dawley rats following two-year oral treatment with dioxin-like compounds |
| Q40031954 | Quantitative analysis of aryl hydrocarbon receptor activation using fluorescence-based cell imaging--a high-throughput mechanism-based assay for drug discovery |
| Q41569966 | Quantitative structure-activity relationships in substrates, inducers, and inhibitors of cytochrome P4501 (CYP1). |
| Q84530768 | RNA expressions of AHR, ARNT and CYP1B1 are influenced by AHR Arg554Lys polymorphism |
| Q57409034 | Rainbow trout cell bioassay-derived relative potencies for halogenated aromatic hydrocarbons: Comparison and sensitivity analysis |
| Q37352919 | Receptor interactions by polybrominated diphenyl ethers versus polychlorinated biphenyls: a theoretical Structure-activity assessment |
| Q28360351 | Receptor-dependent mechanisms of glucocorticoid and dioxin-induced cleft palate |
| Q30321069 | Receptor-mediated effects of chlorinated hydrocarbons |
| Q28570416 | Recombinant expression of aryl hydrocarbon receptor for quantitative ligand-binding analysis |
| Q53502950 | Regulation of 2-acetylaminofluorene-and 3-methylcholanthrene-mediated induction of multidrug resistance and cytochrome P450IA gene family expression in primary hepatocyte cultures and rat liver |
| Q35307354 | Regulation of CYP1A1 and Inflammatory Cytokine by NCOA7 Isoform 4 in Response to Dioxin Induced Airway Inflammation |
| Q49544001 | Regulation of Innate Lymphoid Cells by Aryl Hydrocarbon Receptor. |
| Q28370342 | Regulation of cytochrome P4501B1 (CYP1B1) in mouse embryo fibroblast (C3H10T1/2) cells by protein kinase C (PKC) |
| Q41110649 | Regulation of dioxin receptor function by omeprazole |
| Q28378800 | Regulation of glucose transport in the NIH 3T3 L1 preadipocyte cell line by TCDD |
| Q28342819 | Regulation of mouse CYP1A1 gene expression by dioxin: requirement of two cis-acting elements during induction |
| Q49990707 | Regulation of the Immune Response by the Aryl Hydrocarbon Receptor |
| Q24293065 | Regulation of transactivation function of the aryl hydrocarbon receptor by the Epstein-Barr virus-encoded EBNA-3 protein |
| Q39511119 | Relationship of basic research in toxicology to environmental standard setting: the case of polybrominated biphenyls in Michigan |
| Q40732476 | Relationships among the cell cycle, cell proliferation, and aryl hydrocarbon receptor expression in PLHC-1 cells |
| Q35029793 | Relationships between environmental organochlorine contaminant residues, plasma corticosterone concentrations, and intermediary metabolic enzyme activities in Great Lakes herring gull embryos |
| Q40970439 | Relative potencies of PAHs and PCBs based on the response of human cells |
| Q37565671 | Relevance of the aryl hydrocarbon receptor (AhR) for clinical toxicology |
| Q38325252 | Repression of dioxin signal transduction in fibroblasts. Identification Of a putative repressor associated with Arnt |
| Q73368747 | Reproductive effects of hexachlorobenzene in female rats |
| Q43258036 | Reproductive lesions in female Harlan Sprague-Dawley rats following two-year oral treatment with dioxin and dioxin-like compounds |
| Q35031029 | Requirement for metabolic activation of acetylaminofluorene to induce multidrug gene expression |
| Q38356998 | Resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity and abnormal liver development in mice carrying a mutation in the nuclear localization sequence of the aryl hydrocarbon receptor. |
| Q27335193 | Restoration of dioxin-induced damage to fetal steroidogenesis and gonadotropin formation by maternal co-treatment with α-lipoic acid |
| Q41150794 | Retinoic acid affects the expression rate of the differentiation-related genes aryl hydrocarbon receptor, ARNT and keratin 4 in proliferative keratinocytes only |
| Q28321903 | Ribonuclease inhibits Ah receptor transformation in vitro |
| Q34940048 | Risk assessment of low-level chemical exposures from consumer products under the U.S. Consumer Product Safety Commission chronic hazard guidelines |
| Q62086878 | Risk for animal and human health related to the presence of dioxins and dioxin‐like PCBs in feed and food |
| Q38751346 | Role of aryl hydrocarbon receptor polymorphisms on TCDD-mediated CYP1B1 induction and IgM suppression by human B cells |
| Q39696675 | Role of cytochrome P-450 in porphyria caused by halogenated aromatic compounds |
| Q40857331 | Role of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer, and signal transduction. |
| Q37108803 | Role of the aryl hydrocarbon receptor in carcinogenesis and potential as a drug target |
| Q39309007 | Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target. |
| Q36680876 | Role of the ligand in intracellular receptor function: receptor affinity determines activation in vitro of the latent dioxin receptor to a DNA-binding form |
| Q37368782 | Roles of UDP-glucuronosyltransferases in chemical carcinogenesis |
| Q41269934 | Science policy choices and the estimation of cancer risk associated with exposure to TCDD. |
| Q34419026 | Selected lesions of dioxin in laboratory rodents |
| Q35031749 | Selective retention of hydroxylated PCB metabolites in blood |
| Q51312956 | Serum aryl hydrocarbon receptor ligand activity is associated with insulin resistance and resulting type 2 diabetes. |
| Q43635054 | Serum dioxin and hepatic abnormalities in veterans of Operation Ranch Hand |
| Q28569040 | Significant suppression of rat liver aldolase B by a toxic coplanar polychlorinated biphenyl, 3,3',4,4',5-pentachlorobiphenyl |
| Q38100938 | Solution by dilution?--A review on the pollution status of the Yangtze River |
| Q73698970 | Species-specific alteration of hepatic glucose 6-phosphate dehydrogenase activity with coplanar polychlorinated biphenyl: evidence for an Ah-receptor-linked mechanism |
| Q37562326 | Specific Caleosin/Peroxygenase and Lipoxygenase Activities Are Tissue-Differentially Expressed in Date Palm (Phoenix dactylifera L.) Seedlings and Are Further Induced Following Exposure to the Toxin 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q33827688 | Specific protein-DNA interactions at a xenobiotic-responsive element: copurification of dioxin receptor and DNA-binding activity. |
| Q35141693 | Stability of the aryl hydrocarbon receptor and its regulated genes in the low activity variant of Hepa-1 cell line |
| Q34940384 | Stepping backward to improve assessment of PCB congener toxicities |
| Q72370936 | Stimulation of NADPH-dependent reactive oxygen species formation and DNA damage by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat peritoneal lavage cells |
| Q41564389 | Stimulatory effect of the CYPlAl inducer 2,3,7,8-tetrachlorodibenzo-pdioxin on the reproduction of HIV-1 in human lymphoid cell culture |
| Q33548534 | Stochastic modeling of B lymphocyte terminal differentiation and its suppression by dioxin |
| Q45953721 | Structural analysis and the effect of cyclo(His-Pro) dipeptide on neurotoxins--a dynamics and density functional theory study. |
| Q40963146 | Structural and mechanistic aspects of transcriptional induction of cytochrome P450 1A1 by benzimidazole derivatives in rat hepatoma H4IIE cells |
| Q38845142 | Structural modeling of the AhR:ARNT complex in the bHLH-PASA-PASB region elucidates the key determinants of dimerization. |
| Q28203447 | Structure and expression of the Ah receptor repressor gene |
| Q40741144 | Structure dependent induction of CYP1A by polychlorinated biphenyls in hepatocytes of male castrated pigs |
| Q42246695 | Structure elucidation of some minor components of the polybromobiphenyl mixture, Firemaster |
| Q41447733 | Structure-activity relationships of dietary indoles: a proposed mechanism of action as modifiers of xenobiotic metabolism |
| Q35035475 | Structure-induction versus structure-toxicity relationships for polychlorinated biphenyls and related aromatic hydrocarbons |
| Q42105992 | Studies of the influence of chloro-substituent sites and conformational energy in polychlorinated biphenyls on uroporphyrin formation in chick-embryo liver cell cultures |
| Q72051963 | Subchronic effects of 2,3,7,8-TCDD or PCBs on thyroid hormone metabolism: use in risk assessment |
| Q28333972 | Superinduction of 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible expression of aldehyde dehydrogenase by the inhibition of protein synthesis |
| Q23919663 | Superinduction of CYP1A1 gene expression. Regulation of 2,3,7,8- tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximide |
| Q38336354 | Suppression of C/EBPalpha and induction of C/EBPbeta by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse adipose tissue and liver |
| Q87829455 | Suppression of the IgM Response by Aryl Hydrocarbon Receptor Activation in Human Primary B Cells Involves Impairment of Immunoglobulin Secretory Processes |
| Q28371123 | Suppressive effects of estradiol on 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated transcriptional activation of murine Cyp1a-1 in mouse hepatoma Hepa 1c1c7 cells |
| Q41938430 | Synergism of iron and hexachlorobenzene inhibits hepatic uroporphyrinogen decarboxylase in inbred mice |
| Q34635734 | Synergistic effect of 2,2',4,4',5,5'-hexachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin on hepatic porphyrin levels in the rat. |
| Q42787123 | Synthesis and biological evaluation of 2,3'-diindolylmethanes as agonists of aryl hydrocarbon receptor |
| Q44608946 | T Cell-Specific Disruption of Arylhydrocarbon Receptor Nuclear Translocator (Arnt) Gene Causes Resistance to 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Thymic Involution |
| Q67278794 | TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) causes increases in protein kinases particularly protein kinase C in the hepatic plasma membrane of the rat and the guinea pig |
| Q42246834 | TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) causes reduction in the low density lipoprotein (LDL) receptor activities in the hepatic plasma membrane of the guinea pig and rat |
| Q53909950 | TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) reduces lipoprotein lipase activity in the adipose tissue of the guinea pig. |
| Q48618415 | TCDD Decreases Rapidly and Persistently Serum Melatonin Concentration Without Morphologically Affecting the Pineal Gland in TCDD-Resistant Han/Wistar Rats |
| Q35012642 | TCDD increases inhibin A production by human luteinized granulosa cells in vitro |
| Q23919655 | TCDD-inducible poly (ADP-ribose) polmerase: a novel response to 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q34272223 | Tampons, dioxins, and endometriosis |
| Q89507021 | Taxol Induces Brk-dependent Prosurvival Phenotypes in TNBC Cells through an AhR/GR/HIF-driven Signaling Axis |
| Q53392067 | Teratogenic potency of 2,3,4,7,8-pentachlorodibenzofuran and of three mixtures of polychlorinated dibenzo-p-dioxins and dibenzofurans in mice. Problems with risk assessment using TCDD toxic-equivalency factors. |
| Q43635321 | Teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the expression of EGF and/or TGF-alpha |
| Q71383575 | Teratological studies on the TCDD congener 3,3',4,4'-tetrachloroazoxybenzene in sensitive and nonsensitive mouse strains: evidence for direct effect on embryonic tissues |
| Q35094599 | The 2001 Veylien Henderson Award of the Society of Toxicology of Canada. Positive and negative transcriptional regulation of cytochromes P450 by polycyclic aromatic hydrocarbons |
| Q72689132 | The Ah locus: Correlation of intranuclear appearance of inducer-receptor complex with induction of cytochrome P1-450 mRNA |
| Q38317576 | The Ah locus: genetic differences in toxicity, cancer, mutation, and birth defects |
| Q36390569 | The Ah receptor and the mechanism of dioxin toxicity |
| Q38185125 | The Ah receptor in stem cell cycling, regulation, and quiescence |
| Q28326910 | The Ah receptor, cytochrome P450IA1 mRNA induction, and aryl hydrocarbon hydroxylase in a human lymphoblastoid cell line |
| Q35890891 | The AhR Ligand, TCDD, Regulates Androgen Receptor Activity Differently in Androgen-Sensitive versus Castration-Resistant Human Prostate Cancer Cells |
| Q30318583 | The AhR is constitutively activated and affects granulosa cell features in the human cell line KGN |
| Q87962958 | The Aryl Hydrocarbon Receptor (AhR) as a Drug Target for Cancer Chemotherapy |
| Q50327400 | The Aryl Hydrocarbon Receptor and Tumor Immunity. |
| Q33952165 | The Aryl Hydrocarbon Receptor: A Target for Breast Cancer Therapy |
| Q24530042 | The Comparative Toxicogenomics Database (CTD). |
| Q58651156 | The Possibilities of Reduction of Polychlorinated Dibenzo-P-Dioxins and Polychlorinated Dibenzofurans Emission |
| Q28215966 | The Q-rich subdomain of the human Ah receptor transactivation domain is required for dioxin-mediated transcriptional activity |
| Q41975121 | The activation mechanism of the aryl hydrocarbon receptor (AhR) by molecular chaperone HSP90. |
| Q34201337 | The aqueous solubility of some herbicidal by-side toxic impurities: predicted data of the 399 chlorinated trans-azoxybenzene congeners |
| Q36559117 | The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin |
| Q33861124 | The aromatic hydrocarbon receptor, transcription, and endocrine aspects of dioxin action |
| Q45025050 | The aryl hydrocarbon (Ah) receptor transcriptional regulator hepatitis B virus X-associated protein 2 antagonizes p23 binding to Ah receptor-Hsp90 complexes and is dispensable for receptor function |
| Q38344514 | The aryl hydrocarbon receptor (AhR) tyrosine 9, a residue that is essential for AhR DNA binding activity, is not a phosphoresidue but augments AhR phosphorylation |
| Q40659865 | The aryl hydrocarbon receptor antagonist, 3'methoxy-4'nitroflavone, attenuates 2,3,7,8-tetrachlorodibenzo-p-dioxin-dependent regulation of growth factor signaling and apoptosis in the MCF-10A cell line. |
| Q37397536 | The aryl hydrocarbon receptor as a target for estrogen receptor-negative breast cancer chemotherapy |
| Q39535889 | The aryl hydrocarbon receptor interacts with ATP5α1, a subunit of the ATP synthase complex, and modulates mitochondrial function |
| Q23917017 | The aryl hydrocarbon receptor interacts with nuclear factor erythroid 2-related factor 2 to mediate induction of NAD(P)H:quinoneoxidoreductase 1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q28538111 | The aryl hydrocarbon receptor is constitutively active in advanced prostate cancer cells |
| Q59959371 | The aryl hydrocarbon receptor: A comparative perspective |
| Q24338766 | The aryl hydrocarbon receptor: a perspective on potential roles in the immune system |
| Q41557722 | The comparative biologic and toxic potencies of polychlorinated biphenyls and polybrominated biphenyls |
| Q37155403 | The conversion of rapid TCCD nongenomic signals to persistent inflammatory effects via select protein kinases in MCF10A cells |
| Q47806695 | The crystal structure of the AhRR-ARNT heterodimer reveals the structural basis of the repression of AhR-mediated transcription |
| Q37944828 | The cytochrome P450 I gene family of microsomal hemoproteins and their role in the metabolic activation of chemicals |
| Q28339524 | The cytogenetic and hepatotoxic effects of dioxin on mouse liver cells |
| Q37815733 | The determination of polychlorinated biphenyl residues: a review with special reference to foods |
| Q36801793 | The dioxin (aryl hydrocarbon) receptor as a model for adaptive responses of bHLH/PAS transcription factors |
| Q68419281 | The dioxin receptor: Characterization of its DNA-binding properties |
| Q41128193 | The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on tumor necrosis factor (TNF) production by peritoneal cells |
| Q38618889 | The emerging role of aryl hydrocarbon receptor in the activation and differentiation of Th17 cells. |
| Q54635090 | The importance of biological realism in dioxin risk assessment models. |
| Q85023093 | The induction by monochlorodibenzofuran isomers of xenobiotic metabolizing systems in cell lines derived from rat and human hepatoma |
| Q84789906 | The interactions of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 6-methyl-1,3,8-trichlorodibenzofuran in chick embryo hepatocytes |
| Q37595515 | The mammalian aryl hydrocarbon (Ah) receptor: from mediator of dioxin toxicity toward physiological functions in skin and liver |
| Q35595674 | The mammalian basic helix-loop-helix/PAS family of transcriptional regulators |
| Q35030918 | The mechanism of dioxin toxicity: relationship to risk assessment |
| Q34536448 | The molecular basis for differential dioxin sensitivity in birds: role of the aryl hydrocarbon receptor |
| Q35035934 | The molecular basis of chemical toxicity |
| Q41772682 | The mouse and human Ah receptor differ in recognition of LXXLL motifs |
| Q46208435 | The mycotoxin, patulin, increases the expression of PXR and AhR and their target cytochrome P450s in primary cultured human hepatocytes. |
| Q67924749 | The possible role of phospholipase A2 in hepatic microsomal lipid peroxidation induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats |
| Q35012728 | The rat as a model in developmental immunotoxicology |
| Q73689376 | The relative abilities of TCDD and its congeners to induce oxidative stress in the hepatic and brain tissues of rats after subchronic exposure |
| Q44627910 | The role of antioxidant enzymes in TCDD-induced oxidative stress in various brain regions of rats after subchronic exposure |
| Q37911282 | The role of endogenous aryl hydrocarbon receptor signaling in cardiovascular physiology |
| Q28359863 | The role of the Ah locus in hexachlorobenzene-induced porphyria. Studies in congenic C57BL/6J mice |
| Q36946755 | The search for endogenous activators of the aryl hydrocarbon receptor |
| Q37137946 | The selective aryl hydrocarbon receptor modulator 6-methyl-1,3,8-trichlorodibenzofuran inhibits prostate tumor metastasis in TRAMP mice. |
| Q34141139 | The silencing mediator of retinoic acid and thyroid hormone receptors can interact with the aryl hydrocarbon (Ah) receptor but fails to repress Ah receptor-dependent gene expression |
| Q33916567 | The specific DNA binding activity of the dioxin receptor is modulated by the 90 kd heat shock protein |
| Q44251445 | The subdomains of the transactivation domain of the aryl hydrocarbon receptor (AhR) inhibit AhR and estrogen receptor transcriptional activity |
| Q40747739 | The toxicokinetics and metabolism of polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) and their relevance for toxicity. |
| Q46669070 | The toxicological significance of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds in human adipose tissue |
| Q33643360 | The transcription factor aryl hydrocarbon receptor nuclear translocator functions as an estrogen receptor beta-selective coactivator, and its recruitment to alternative pathways mediates antiestrogenic effects of dioxin |
| Q44252647 | The transcriptional activation of the human copper/zinc superoxide dismutase gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin through two different regulator sites, the antioxidant responsive element and xenobiotic responsive element |
| Q40601327 | The use of carbon thirteen nuclear magnetic resonance spectra to predict dioxin and furan binding affinities to the aryl hydrocarbon receptor |
| Q30679025 | The use of quantitative histological and molecular data for risk assessment and biologically based model development |
| Q45145076 | Therapeutic basis of vidarabine on adenovirus-induced haemorrhagic cystitis |
| Q57009044 | Thermodynamical and quantum-chemical characterization and chemometrical selection of representative congeners oftrans-chloroazoxybenzene |
| Q73291743 | Thymocyte development in Ah-receptor-deficient mice is refractory to TCDD-inducible changes |
| Q35009427 | Tissue specific expression of the rat Ah-receptor and ARNT mRNAs |
| Q38783074 | Toward a molecular understanding of the photosensitizer-copper interaction for tumor destruction. |
| Q24289511 | Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples |
| Q34659943 | Toxic effects in C57B1/6 and DBA/2 mice following consumption of halogenated aromatic hydrocarbon-contaminated Great Lakes coho salmon (Oncorhynchus kisutch Walbaum) |
| Q74514099 | Toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds |
| Q41623622 | Toxic effects of griseofulvin: disease models, mechanisms, and risk assessment. |
| Q43617180 | Toxic effects of the herbicide 2,4-dichlorophenoxyacetic acid on lymphoid organs of the rat. |
| Q24682490 | Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife |
| Q45305246 | Toxicity and 7-ethoxyresorufin O-deethylase-inducing potency of coplanar polychlorinated biphenyls (PCBs) in chick embryos |
| Q68027632 | Toxicity and EROD-inducing potency of 24 polycyclic aromatic hydrocarbons (PAHs) in chick embryos |
| Q35035491 | Toxicity and fetotoxicity of TCDD, TCDF and PCB isomers in rhesus macaques (Macaca mulatta). |
| Q41697693 | Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in vitro: H4IIEC3-derived 5L hepatoma cells as a model system |
| Q39495916 | Toxicity of chlorinated aromatic compounds in animals and humans: in vitro approaches to toxic mechanisms and risk assessment |
| Q67947915 | Toxicity to chicken embryos of organic extracts from airborne particulates separated into five sizes |
| Q37253515 | Toxicogenomic evaluation of long-term hepatic effects of TCDD in immature, ovariectomized C57BL/6 mice |
| Q37761179 | Toxicology mechanism of the persistent organic pollutants (POPs) in fish through AhR pathway. |
| Q36568936 | Transactivation domains facilitate promoter occupancy for the dioxin-inducible CYP1A1 gene in vivo |
| Q38737467 | Transcript variations, phylogenetic tree and chromosomal localization of porcine aryl hydrocarbon receptor (AhR) and AhR nuclear translocator (ARNT) genes. |
| Q37332482 | Transcription-dependent and transcription-independent nucleosome disruption induced by dioxin |
| Q42279330 | Transcriptional activation by the mouse Ah receptor. Interplay between multiple stimulatory and inhibitory functions |
| Q77436493 | Transcriptional suppression of estrogen receptor gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) |
| Q28378636 | Transformation of the aryl hydrocarbon receptor to a DNA-binding form is accompanied by release of the 90 kDa heat-shock protein and increased affinity for 2,3,7,8-tetrachlorodibenzo-p-dioxin |
| Q72188503 | Transforming growth factor-beta 1 inhibits TCDD-induced cytochrome P450IA1 expression in human lung cancer A549 cells |
| Q73694976 | Tryptanthrins: a novel class of agonists of the aryl hydrocarbon receptor |
| Q69353261 | Tumor-promoting activity and cytotoxicity of 3,4,3',4'-tetrachlorobiphenyl on N-nitrosomorpholine-induced murine liver foci |
| Q42280253 | Tumor-promoting effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and phenobarbital in initiated weanling Sprague-Dawley rats: a quantitative, phenotypic, and ras p21 protein study |
| Q59068749 | Tumour promotion by TCDD in skin of HRS/J hairless mice |
| Q40693472 | UDP-glucuronosyltransferases and their role in metabolism and disposition of carcinogens. |
| Q72718605 | Ultrastructure of the cortical epithelium of the rat thymus after in vivo exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) |
| Q36388135 | Uncertainties related to the assignment of a toxic equivalency factor for 1,2,3,4,6,7,8,9-octachlorodibenzo-p-dioxin |
| Q43906467 | Up-regulated expression of genes encoding Hrk and IL-3R beta subunit by TCDD in vivo and in vitro |
| Q69509374 | Uptake of 2,3,7,8-tetrachlorodibenzo-p-dioxin from plasma lipoproteins by cultured human fibroblasts |
| Q50428210 | Uptake of radiolabeled 3,3',4,4'-tetrachlorobiphenyl into Japanese quail egg compartments and embryo following air cell and albumen injection |
| Q42858662 | Uroporphyria produced in mice by 20-methylcholanthrene and 5-aminolaevulinic acid |
| Q36916038 | Utilization of quantitative structure-activity relationships (QSARs) in risk assessment: Alkylphenols |
| Q35589027 | Very low-dose (femtomolar) 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) disrupts steroidogenic enzyme mRNAs and steroid secretion by human luteinizing granulosa cells |
| Q77816598 | Water-soluble 2,3,7,8-tetrachlorodibenzo-p-dioxin complex with human alpha-fetoprotein: properties, toxicity in vivo and antitumor activity in vitro |
| Q24814829 | Wildlife as sentinels of human health effects in the Great Lakes--St. Lawrence basin |
| Q34831650 | Workshop on perinatal exposure to dioxin-like compounds. VI. Role of biomarkers |
| Q37912165 | Xenobiotic metabolomics: major impact on the metabolome |
| Q28240487 | Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element |
| Q40456814 | Xenobiotic-inducible transcription of cytochrome P450 genes. |
| Q35639784 | Zebrafish cardiotoxicity: the effects of CYP1A inhibition and AHR2 knockdown following exposure to weak aryl hydrocarbon receptor agonists |
| Q42678174 | cDNA cloning and characterization of an aryl hydrocarbon receptor from the harbor seal (Phoca vitulina): a biomarker of dioxin susceptibility? |
| Q28585718 | cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt) |
| Q42686965 | cDNA cloning of an aryl hydrocarbon receptor from Baikal seals (Phoca sibirica). |
| Q28343428 | p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells |
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