The activation mechanism of the aryl hydrocarbon receptor (AhR) by molecular chaperone HSP90.

scientific article published on 16 September 2014

The activation mechanism of the aryl hydrocarbon receptor (AhR) by molecular chaperone HSP90. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.FOB.2014.09.003
P8608Fatcat IDrelease_s3cfrybzzzhvnlwv37be7jlqwa
P932PMC publication ID4208086
P698PubMed publication ID25349783
P5875ResearchGate publication ID265910454

P2093author name stringMichiro Otaka
Tomoya Okamoto
Hideaki Itoh
Miki Hosaka
Soh Yamamoto
Asami Haga
Ewa Grave
Hirotaka Okada
Shiho Yoshida
Noriko Tsuji
Shiori Hatakeyama
Kana Fukuda
Yuhtaroh Nagata
Kazuhiro Sekine
Kei Ohtaka
P2860cites workMultiple roles of ligand in transforming the dioxin receptor to an active basic helix-loop-helix/PAS transcription factor complex with the nuclear protein ArntQ39446848
P450 genes: structure, evolution, and regulationQ39664988
A novel chaperone-activity-reducing mechanism of the 90-kDa molecular chaperone HSP90.Q42158646
The Ah receptor can bind ligand in the absence of receptor-associated heat-shock protein 90.Q46023296
Response of murine epidermis to 2,3,7,8-tetrachlorodibenzo-p-dioxin: Interaction of the Ah and hr lociQ72957377
Role of heat shock protein 90 dissociation in mediating agonist-induced activation of the aryl hydrocarbon receptorQ73316901
Aryl hydrocarbon receptor signaling in rainbow trout hepatocytes: role of hsp90 and the proteasomeQ80604355
Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathwayQ24310405
Protein-protein interaction via PAS domains: role of the PAS domain in positive and negative regulation of the bHLH/PAS dioxin receptor-Arnt transcription factor complexQ24598943
Identification of functional domains of the aryl hydrocarbon receptorQ28284732
The aryl hydrocarbon receptor complex and the control of gene expressionQ28386260
Functional role of AhR in the expression of toxic effects by TCDDQ28609386
PAS domains: internal sensors of oxygen, redox potential, and lightQ29615332
2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of ToxicityQ29618527
The PAS superfamily: sensors of environmental and developmental signalsQ29622907
Ligand displaces heat shock protein 90 from overlapping binding sites within the aryl hydrocarbon receptor ligand-binding domainQ35266378
The mammalian basic helix-loop-helix/PAS family of transcriptional regulatorsQ35595674
The tumor suppressor Kruppel-like factor 6 is a novel aryl hydrocarbon receptor DNA binding partnerQ36852614
The chaperone Hsp90: changing partners for demanding clientsQ38090850
Structure, function and regulation of the hsp90 machineryQ38117496
Regulatory role of the 90-kDa-heat-shock protein (Hsp90) and associated factors on gene expression.Q38175769
A cellular factor stimulates ligand-dependent release of hsp90 from the basic helix-loop-helix dioxin receptorQ38309573
Aryl hydrocarbon receptor is a target of 17-Allylamino-17-demethoxygeldanamycin and enhances its anticancer activity in lung adenocarcinoma cells.Q39228304
???Q28210976
P921main subjectmolecular chaperonesQ422496
P304page(s)796-803
P577publication date2014-09-16
P1433published inFEBS Open BioQ27724062
P1476titleThe activation mechanism of the aryl hydrocarbon receptor (AhR) by molecular chaperone HSP90.
P478volume4

Reverse relations

cites work (P2860)
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Q26765223Intestinal inflammation and the diet: Is food friend or foe?
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