Control of T-cell development by the pre-T and alpha beta T-cell receptor

scientific article published on September 1995

Control of T-cell development by the pre-T and alpha beta T-cell receptor is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1749-6632.1995.TB26648.X
P8608Fatcat IDrelease_s5koht2movclxcnqli5ixo5veu
P698PubMed publication ID7486699

P2093author name stringVon Boehmer H
P2860cites workGenes and antibodiesQ28185156
Early expression of a T-cell receptor beta-chain transgene suppresses rearrangement of the V gamma 4 gene segmentQ33687935
Positive selection of transgenic receptor-bearing thymocytes by Kb antigen is altered by Kb mutations that involve peptide bindingQ33741290
Stochastic component to development of class I major histocompatibility complex-specific T cellsQ34927276
T cells respond preferentially to antigens that are similar to self H-2.Q35333156
On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?Q36340069
Suppression of T cells specific for the nonthymic parental H-2 haplotype in thymus-grafted chimerasQ36343268
Regulation of thymocyte development through CD3. I. Timepoint of ligation of CD3 epsilon determines clonal deletion or induction of developmental programQ36361460
Positive selection of CD8+ T cells induced by major histocompatibility complex binding peptides in fetal thymic organ cultureQ36361722
Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilonQ36703755
Major histocompatibility complex-linked immune-responsiveness is acquired by lymphocytes of low-responder mice differentiating in thymus of high-responder miceQ37586973
A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoproteinQ41520076
Clonal deletion of immature CD4+8+ thymocytes in suspension culture by extrathymic antigen-presenting cellsQ41807593
Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptorQ41902311
Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stagesQ44151375
I-E expression and susceptibility to parasite infectionQ44674271
Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytesQ44851100
Evidence for a differential avidity model of T cell selection in the thymusQ45155438
Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.Q45999974
Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptorQ46155874
Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes.Q46778527
The selection of the α,β heterodimeric T-cell receptor for antigenQ47688392
Rearrangement and diversity of T cell receptor beta chain genes in thymocytes: a critical role for the beta chain in developmentQ48120520
In transgenic mice the introduced functional T cell receptor beta gene prevents expression of endogenous beta genesQ48327246
Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice.Q50800754
Another view of the selective model of thymocyte selection.Q51142565
An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.Q52511681
Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cellsQ58991849
The generation of mature T cells requires interaction of the αβ T-cell receptor with major histocompatibility antigensQ59073001
Positive selection of antigen-specific T cells in thymus by restricting MHC moleculesQ59080081
P407language of work or nameEnglishQ1860
P304page(s)52-61
P577publication date1995-09-01
P1433published inAnnals of the New York Academy of SciencesQ2431664
P1476titleControl of T-cell development by the pre-T and alpha beta T-cell receptor
P478volume766

Reverse relations

cites work (P2860)
Q28769430Evolution of T-cell receptor gamma and delta constant region and other T-cell-related proteins in the human-rodent-artiodactyl triplet
Q52191951Exit of the pre-TCR from the ER/cis-Golgi is necessary for signaling differentiation, proliferation, and allelic exclusion in immature thymocytes.
Q36237886Maintenance of TCR clonality in T cells expressing genes for two TCR heterodimers
Q52191905Separately expressed T cell receptor alpha and beta chain transgenes exert opposite effects on T cell differentiation and neoplastic transformation.
Q35751012T-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex.
Q41514626TCR zeta chain in T cell development and selection
Q89474911The actin remodeling protein cofilin is crucial for thymic αβ but not γδ T-cell development
Q33932904The requirement for pre-TCR during thymic differentiation enforces a developmental pause that is essential for V-DJβ rearrangement
Q36822300The role of the LAT-PLC-gamma1 interaction in T regulatory cell function
Q34792441Uncertainties - discrepancies in immunology