CD3-induced apoptosis of CD4+CD8+ thymocytes in the absence of clonotypic T cell antigen receptor

scientific article published on 01 May 1996

CD3-induced apoptosis of CD4+CD8+ thymocytes in the absence of clonotypic T cell antigen receptor is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/EJI.1830260509
P698PubMed publication ID8647161

P2093author name stringNakauchi H
Tanaka S
Tsuda S
Tokoro Y
Takahama Y
P2860cites workT cell receptor antagonist peptides induce positive selectionQ29618820
Analysis and expression of a cloned pre-T cell receptor geneQ30193904
Identification of a monoclonal antibody specific for a murine T3 polypeptideQ34602051
Surface expression of a T cell receptor beta (TCR-beta) chain in the absence of TCR-alpha, -delta, and -gamma proteinsQ36230424
Mice lacking major histocompatibility complex class I and class II moleculesQ36271130
Developmentally regulated expression of CD3 components independent of clonotypic T cell antigen receptor complexes on immature thymocytesQ36363821
Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilonQ36703755
The T cell antigen receptor: insights into organelle biologyQ38023531
Molecular and cellular events of T cell developmentQ38220900
Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.Q38321834
The T cell receptor/CD3 complex: a dynamic protein ensembleQ39647384
A role for a pre-T-cell receptor in T-cell developmentQ40620699
A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoproteinQ41520076
Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cellsQ42806482
Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stagesQ44151375
Evidence for a differential avidity model of T cell selection in the thymusQ45155438
Expression and function of the CD3-antigen receptor on murine CD4+8+ thymocytesQ46524941
Another view of the selective model of thymocyte selection.Q51142565
Entry of CD4-CD8- immature thymocytes into the CD4/CD8 developmental pathway is controlled by tyrosine kinase signals that can be provided through TCR components.Q52214030
Positive selection of CD4+ T cells by TCR ligation without aggregation even in the absence of MHC.Q52214778
CD3 epsilon-mediated signals rescue the development of CD4+CD8+ thymocytes in RAG-2-/- mice in the absence of TCR beta chain expression.Q52215925
The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR.Q54344555
T cell tolerance by clonal elimination in the thymusQ56922465
CD3 components at the surface of pro-T cells can mediate pre-T cell developmentin vivoQ58451232
Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cellsQ58991849
Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic culturesQ59070003
Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cellsQ59070257
T-cell apoptosis detected in situ during positive and negative selection in the thymusQ59087078
Identification of a murine monoclonal antibody specific for an allotypic determinant on mouse CD3Q61863707
P433issue5
P921main subjectthymocyteQ7799635
P304page(s)1012-1017
P577publication date1996-05-01
P1433published inEuropean Journal of ImmunologyQ5412727
P1476titleCD3-induced apoptosis of CD4+CD8+ thymocytes in the absence of clonotypic T cell antigen receptor
P478volume26

Reverse relations

cites work (P2860)
Q35834615An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis
Q44556255Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.
Q52107361In vivo ligation of CD3 on neonatal scid thymocytes blocks gamma-irradiation-induced TCRbeta rearrangements and thymic lymphomagenesis.
Q44937387Thymic lymphoproliferative disease after successful correction of CD40 ligand deficiency by gene transfer in mice

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