scholarly article | Q13442814 |
P819 | ADS bibcode | 2014PLoSO...987116K |
P356 | DOI | 10.1371/JOURNAL.PONE.0087116 |
P932 | PMC publication ID | 3900716 |
P698 | PubMed publication ID | 24466333 |
P5875 | ResearchGate publication ID | 259920565 |
P2093 | author name string | Stanley Lipkowitz | |
Stephen C Kales | |||
Marion M Nau | |||
Anand S Merchant | |||
P2860 | cites work | cbl-3: a new mammalian cbl family protein | Q22009959 |
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53 | Q22253350 | ||
Cbl-c suppresses v-Src-induced transformation through ubiquitin-dependent protein degradation | Q24301400 | ||
Cloning and characterization of cbl-b: a SH3 binding protein with homology to the c-cbl proto-oncogene | Q24322680 | ||
LIM domain recognition of a tyrosine-containing tight turn | Q24322821 | ||
Shc and Enigma are both required for mitogenic signaling by Ret/ptc2. | Q24533621 | ||
ret transforming gene encodes a fusion protein homologous to tyrosine kinases | Q24628687 | ||
The PDZ domain of the LIM protein enigma binds to beta-tropomyosin | Q24648940 | ||
RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis | Q26853207 | ||
Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b | Q27646953 | ||
The LIM domain: regulation by association | Q28137861 | ||
cbl-b inhibits epidermal growth factor receptor signaling | Q28139234 | ||
Genetics of Hirschsprung disease | Q28139433 | ||
Characterization of the ret proto-oncogene products expressed in mouse L cells | Q28265050 | ||
The Cbl interactome and its functions | Q28277251 | ||
Multiple GPI-anchored receptors control GDNF-dependent and independent activation of the c-Ret receptor tyrosine kinase | Q28575205 | ||
Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation | Q28580654 | ||
Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain | Q29614381 | ||
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1 | Q29617290 | ||
Distinct turnover of alternatively spliced isoforms of the RET kinase receptor mediated by differential recruitment of the Cbl ubiquitin ligase | Q33292370 | ||
Altered thymic positive selection and intracellular signals in Cbl-deficient mice | Q33596728 | ||
Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice | Q33776192 | ||
Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization | Q33875853 | ||
Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complex | Q33948376 | ||
Characterization of ret proto-oncogene mRNAs encoding two isoforms of the protein product in a human neuroblastoma cell line | Q33981089 | ||
Multiple endocrine neoplasia type 2 and RET: from neoplasia to neurogenesis | Q34080215 | ||
Comparative genomic organization of the cbl genes | Q34192425 | ||
Enigma negatively regulates p53 through MDM2 and promotes tumor cell survival in mice | Q34360157 | ||
Cbl-c ubiquitin ligase activity is increased via the interaction of its RING finger domain with a LIM domain of the paxillin homolog, Hic 5. | Q34474505 | ||
Identification of novel genes that co-cluster with estrogen receptor alpha in breast tumor biopsy specimens, using a large-scale real-time reverse transcription-PCR approach | Q34589458 | ||
Cbl-3-deficient mice exhibit normal epithelial development | Q36138338 | ||
The rearranged during transfection/papillary thyroid carcinoma tyrosine kinase is an estrogen-dependent gene required for the growth of estrogen receptor positive breast cancer cells | Q36180128 | ||
Alternative splicing results in RET isoforms with distinct trafficking properties. | Q36284502 | ||
EGFRvIII undergoes activation-dependent downregulation mediated by the Cbl proteins | Q36508737 | ||
Specificity of LIM domain interactions with receptor tyrosine kinases | Q36802964 | ||
CD2AP and Cbl-3/Cbl-c constitute a critical checkpoint in the regulation of ret signal transduction | Q37352330 | ||
Inhibition of RET activated pathways: novel strategies for therapeutic intervention in human cancers | Q38042995 | ||
A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer. | Q39751877 | ||
The Ret receptor tyrosine kinase pathway functionally interacts with the ERalpha pathway in breast cancer | Q39981895 | ||
A role for glial cell derived neurotrophic factor induced expression by inflammatory cytokines and RET/GFR alpha 1 receptor up-regulation in breast cancer | Q40033636 | ||
Sorafenib functions to potently suppress RET tyrosine kinase activity by direct enzymatic inhibition and promoting RET lysosomal degradation independent of proteasomal targeting. | Q40100421 | ||
Regulation of stem cell factor receptor signaling by Cbl family proteins (Cbl-b/c-Cbl). | Q40524623 | ||
Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b | Q40531841 | ||
Cbl-b regulates the CD28 dependence of T-cell activation. | Q40904107 | ||
RET activation by germline MEN2A and MEN2B mutations | Q41260398 | ||
Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain | Q42812834 | ||
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b | Q59058408 | ||
The human CBL oncogene | Q70237241 | ||
Molecular implications of RET mutations for pheochromocytoma risk in multiple endocrine neoplasia 2 | Q79354839 | ||
P275 | copyright license | Creative Commons CC0 License | Q6938433 |
P6216 | copyright status | copyrighted, dedicated to the public domain by copyright holder | Q88088423 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | protein ubiquitination | Q3547638 |
P304 | page(s) | e87116 | |
P577 | publication date | 2014-01-01 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | Enigma prevents Cbl-c-mediated ubiquitination and degradation of RETMEN2A | |
P478 | volume | 9 |
Q64231562 | Afadin cooperates with Claudin-2 to promote breast cancer metastasis |
Q27853152 | Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity |
Q38631763 | Differential recruitment of E3-ubiquitin ligase complexes regulates RET isoform internalization |
Q64086696 | Identification of Triple-Negative Breast Cancer Genes and a Novel High-Risk Breast Cancer Prediction Model Development Based on PPI Data and Support Vector Machines |
Q46228906 | Pathologic significance of a novel oncoprotein in thyroid cancer progression |
Q36560048 | RNF135, RING finger protein, promotes the proliferation of human glioblastoma cells in vivo and in vitro via the ERK pathway |
Q38366765 | The RET oncogene in papillary thyroid carcinoma |
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