| scholarly article | Q13442814 |
| P2093 | author name string | Kenneth A Frauwirth | |
| Craig B Thompson | |||
| P2860 | cites work | Role of the CD28 receptor in T-cell activation | Q37881494 |
| The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response | Q39337556 | ||
| B7-dependent T-cell costimulation in mice lacking CD28 and CTLA4. | Q39907809 | ||
| The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A. | Q40850973 | ||
| Cbl-b regulates the CD28 dependence of T-cell activation. | Q40904107 | ||
| Signaling through CD28/CTLA-4 family receptors: puzzling participation of phosphatidylinositol-3 kinase | Q41006886 | ||
| Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B. | Q41079207 | ||
| Immunoreceptor tyrosine-based inhibition motifs | Q41504931 | ||
| The Emerging Role of CTLA-4 as an Immune Attenuator | Q41630509 | ||
| Genetic analysis of protein tyrosine phosphatases | Q41732769 | ||
| Cytotoxic T Lymphocyte Antigen 4 (CTLA-4) Interferes with Extracellular Signal-regulated Kinase (ERK) and Jun NH2-terminal Kinase (JNK) Activation, but Does Not Affect Phosphorylation of T Cell Receptor ζ and ZAP70 | Q41909802 | ||
| A point mutation in CD28 distinguishes proliferative signals from survival signals | Q43558088 | ||
| Lymphocyte signalling: A coordinating role for Vav? | Q47679732 | ||
| Functional responses and costimulator dependence of memory CD4+ T cells | Q52030310 | ||
| Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha | Q52533405 | ||
| ICOS costimulation requires IL-2 and can be prevented by CTLA-4 engagement | Q56905227 | ||
| CTLA-4 (CD152) can inhibit T cell activation by two different mechanisms depending on its level of cell surface expression | Q56905906 | ||
| The CD28-related molecule ICOS is required for effective T cell-dependent immune responses | Q56905959 | ||
| The inhibitory function of CTLA-4 does not require its tyrosine phosphorylation | Q56906426 | ||
| Cutting edge: tyrosine-independent transmission of inhibitory signals by CTLA-4 | Q56906434 | ||
| Studies using antigen-presenting cells lacking expression of both B7-1 (CD80) and B7-2 (CD86) show distinct requirements for B7 molecules during priming versus restimulation of Th2 but not Th1 cytokine production | Q56907534 | ||
| CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes | Q56908828 | ||
| Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4 | Q56908993 | ||
| Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b | Q59058408 | ||
| Elevation of intracellular cyclic AMP induces an anergic-like state in Th1 clones | Q71767651 | ||
| p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes | Q73505007 | ||
| Networking Rho Family GTPases in Lymphocytes | Q74545043 | ||
| CD3- and CD28-dependent induction of PDE7 required for T cell activation | Q77952555 | ||
| ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28 | Q22001503 | ||
| B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production | Q24290870 | ||
| CD28/B7 system of T cell costimulation | Q24313544 | ||
| Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation | Q24675931 | ||
| AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation | Q28139447 | ||
| Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS | Q28139731 | ||
| Characterization of human inducible costimulator ligand expression and function | Q28142816 | ||
| Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor | Q28144319 | ||
| The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase | Q28145635 | ||
| ICOS co-stimulatory receptor is essential for T-cell activation and function | Q28187985 | ||
| PD-L2 is a second ligand for PD-1 and inhibits T cell activation | Q28202471 | ||
| Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes | Q28282689 | ||
| Molecular basis of T cell inactivation by CTLA-4 | Q28291723 | ||
| ICOS is critical for CD40-mediated antibody class switching | Q28589705 | ||
| ICOS is essential for effective T-helper-cell responses | Q28594859 | ||
| Structural analysis of CTLA-4 function in vivo | Q28610379 | ||
| B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha | Q30807749 | ||
| Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines | Q31793569 | ||
| Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo | Q32133119 | ||
| Regulation of protein kinase cascades by protein phosphatase 2A. | Q33632946 | ||
| T cell co-stimulatory molecules other than CD28. | Q33664723 | ||
| T cells: A proliferation of costimulatory molecules. | Q33879734 | ||
| Costimulation in antiviral immunity: differential requirements for CD4(+) and CD8(+) T cell responses | Q33971036 | ||
| On guard--activating NK cell receptors | Q34117069 | ||
| The expanding B7 superfamily: increasing complexity in costimulatory signals regulating T cell function | Q34165325 | ||
| ITAMs versus ITIMs: striking a balance during cell regulation | Q34502855 | ||
| Cytotoxic T lymphocyte antigen 4 (CTLA-4) engagement delivers an inhibitory signal through the membrane-proximal region in the absence of the tyrosine motif in the cytoplasmic tail | Q34505121 | ||
| Adapters in lymphocyte signaling | Q34517916 | ||
| Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis | Q36375265 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 295-299 | |
| P577 | publication date | 2002-02-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Activation and inhibition of lymphocytes by costimulation | |
| P478 | volume | 109 |
| Q35594106 | A CT60G>A polymorphism in the CTLA-4 gene of the recipient may confer susceptibility to acute graft versus host disease after allogeneic hematopoietic stem cell transplantation |
| Q47721941 | A novel feedback mechanism by Ephrin-B1/B2 in T-cell activation involves a concentration-dependent switch from costimulation to inhibition |
| Q26345262 | A role for regulatory T cells in a murine model of epicutaneous toluene diisocyanate sensitization |
| Q38264144 | AMPK in lymphocyte metabolism and function |
| Q39419895 | ASP2409, A Next-Generation CTLA4-Ig, Versus Belatacept in Renal Allograft Survival in Cynomolgus Monkeys |
| Q34517916 | Adapters in lymphocyte signaling |
| Q58698089 | Adhesive Interactions Delineate the Topography of the Immune Synapse |
| Q24795134 | Ageing, autoimmunity and arthritis: Perturbations of TCR signal transduction pathways with ageing - a biochemical paradigm for the ageing immune system |
| Q35809402 | Altered signaling triggered by ligation of the TCR/CD3 receptor in T lymphocytes from patients with systemic lupus erythematosus: the road from anergy to autoimmunity |
| Q95270598 | An Integrative Network Modeling Approach to T CD4 Cell Activation |
| Q37625553 | An immunological overview of allergen specific immunotherapy -- subcutaneous and sublingual routes |
| Q36589870 | Anti-cytotoxic T lymphocyte antigen-4 (CTLA-4) immunotherapy for the treatment of prostate cancer |
| Q33714913 | Antigen-specific suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor: structure optimization and pharmacokinetics |
| Q64094265 | Association Between the CD28 c.17 +3 T>C Polymorphism (rs3116496) and Cancer Risk: An Updated Meta-Analysis |
| Q56897763 | Association of CTLA-4 and TNF-α polymorphism with recurrent miscarriage among North Indian women |
| Q37099555 | Association of the +49 A/G Polymorphism of CTLA4 Gene with Idiopathic Recurrent Spontaneous Abortion in Women in Southwest of Iran |
| Q34190823 | Azathioprine: old drug, new actions |
| Q34207477 | B7S1, a novel B7 family member that negatively regulates T cell activation |
| Q40419059 | BAFF supports human B cell differentiation in the lymphoid follicles through distinct receptors |
| Q36088049 | Block and tackle: CTLA4Ig takes on lupus |
| Q28274563 | Blue honeysuckle fruit (Lonicera caerulea L.) from eastern Russia: phenolic composition, nutritional value and biological activities of its polar extracts |
| Q54408164 | CD28 signaling in primary CD4(+) T cells: identification of both tyrosine phosphorylation-dependent and phosphorylation-independent pathways |
| Q36370694 | CD28, costimulator or agonist receptor? |
| Q35828826 | CD28-mediated regulation of multiple myeloma cell proliferation and survival |
| Q52568487 | CD4+ T cells contribute to postischemic liver injury in mice by interacting with sinusoidal endothelium and platelets. |
| Q36998531 | CD70–CD27 ligation between neural stem cells and CD4+ T cells induces Fas–FasL-mediated T-cell death |
| Q45308646 | CLTA-4 blockade in vivo promotes the generation of short-lived effector CD8 T cells and a more persistent central memory CD4 T cell response |
| Q41321356 | CTLA-4 and CD28 genes' polymorphisms and renal cell carcinoma susceptibility in the Polish population--a prospective study. |
| Q73068588 | Cancer T cell therapy expands |
| Q37869180 | Cell density sensing and size determination |
| Q35564025 | Choice of resident costimulatory molecule can influence cell fate in human naïve CD4+ T cell differentiation |
| Q36370717 | Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor kappaB in regulating mature T cell survival and in vivo function |
| Q36148651 | Combined donor specific transfusion and anti-CD154 therapy achieves airway allograft tolerance |
| Q28291648 | Controlling NF-kappaB activation in T cells by costimulatory receptors |
| Q33212786 | Costimulation by CD137/4-1BB inhibits T cell apoptosis and induces Bcl-xL and c-FLIP(short) via phosphatidylinositol 3-kinase and AKT/protein kinase B. |
| Q51980393 | Costimulation of naive human CD4 T cells through intercellular adhesion molecule-1 promotes differentiation to a memory phenotype that is not strictly the result of multiple rounds of cell division |
| Q27490355 | Costimulatory molecule programmed death-1 in the cytotoxic response during chronic hepatitis C |
| Q35733851 | Costimulatory molecules and T-cell-B-cell interactions |
| Q60046462 | Current Options and Future Directions in Immune Therapy for Glioblastoma |
| Q36337258 | Current imaging strategies in rheumatoid arthritis |
| Q44432122 | Differential Control of Cell Cycle, Proliferation, and Survival of Primary T Lymphocytes by Purine and Pyrimidine Nucleotides |
| Q57279479 | Differential expression of NF-κB pathway genes among peripheral T-cell lymphomas |
| Q35094706 | Disease-modifying therapies in multiple sclerosis: an update on recent and ongoing trials and future strategies |
| Q41528800 | Distinct infiltration of neutrophils in lesion shoulders in ApoE-/- mice. |
| Q45927002 | Distinct kinetics and dynamics of cross-presentation in liver sinusoidal endothelial cells compared to dendritic cells. |
| Q28391838 | Effect of fermented porcine placenta on physical fatigue in mice |
| Q34243893 | Effects of ASKP1240 combined with tacrolimus or mycophenolate mofetil on renal allograft survival in Cynomolgus monkeys |
| Q39325384 | Effects of ICOSLG expressed in mouse hematological neoplasm cell lines in the GVL reaction |
| Q50055700 | Efficacy of Hepatitis B Vaccination among Children in Special Region of Yogyakarta, Indonesia: Evaluation of Humoral and Cellular Immunity |
| Q36545348 | Efficiency of CD19 chimeric antigen receptor-modified T cells for treatment of B cell malignancies in phase I clinical trials: a meta-analysis |
| Q54305225 | Enhanced MHC class I and costimulatory molecules on B16F10 cells byGanoderma lucidumpolysaccharides |
| Q34583014 | Enhanced T-cell signaling in cells bearing linker for activation of T-cell (LAT) molecules resistant to ubiquitylation |
| Q24601345 | Ex Vivo Enzymatic Treatment of Aged CD4 T Cells Restores Cognate T Cell Helper Function and Enhances Antibody Production in Mice |
| Q39465952 | Expression of ICOSLG on Mouse Hematologic Neoplasm Cell Lines and Their Influence on Cytotoxicity in Allogeneic Mixed Lymphocyte Reactions |
| Q39165415 | Expression of Th17-related genes in PHA/IL-2-activated human T cells by Fas signaling via caspase-1- and Stat3-dependent pathway |
| Q54234131 | Fatty acid metabolism in CD8+ T cell memory: Challenging current concepts. |
| Q40369456 | Feline B7.1 and B7.2 proteins produced from swinepox virus vectors are natively processed and biologically active: potential for use as nonchemical adjuvants |
| Q42876926 | Fine tuning and efficient T cell activation with stimulatory aCD3 nanoarrays. |
| Q85954238 | Foxp3+ regulatory T cells are activated in spite of B7-CD28 and CD40-CD40L blockade |
| Q45859343 | Gene transfer of antisense B7.1 attenuates acute rejection against liver allografts in rats |
| Q45873806 | Gene transfer of antisense B7.1 attenuates acute rejection against splenic allografts in rats |
| Q45345418 | HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection |
| Q28078211 | Heterogeneity of B Cell Functions in Stroke-Related Risk, Prevention, Injury, and Repair |
| Q39241549 | Human skin-derived precursor cells are poorly immunogenic and modulate the allogeneic immune response |
| Q95411196 | Immune-Related Antigens, Surface Molecules and Regulatory Factors in Human-Derived Mesenchymal Stromal Cells: The Expression and Impact of Inflammatory Priming |
| Q48532758 | Immunotherapy for cardiovascular disease. |
| Q35794358 | Impaired NFAT and NFκB activation are involved in suppression of CD40 ligand expression by Δ(9)-tetrahydrocannabinol in human CD4(+) T cells |
| Q42146101 | In vitro polyclonal activation of conventional T cells with a CD28 superagonist protects mice from acute graft versus host disease |
| Q35031404 | In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA. |
| Q44972273 | Inducible-costimulator-mediated suppression of human immunodeficiency virus type 1 replication in CD4(+) T lymphocytes |
| Q42703902 | Inhibition and genetic ablation of the B7/CD28 T-cell costimulation axis prevents experimental hypertension |
| Q33827752 | Inhibitors of B7-CD28 costimulation in urologic malignancies |
| Q87954935 | In Vivo Expansion and Antitumor Activity of Coinfused CD28- and 4-1BB-Engineered CAR-T Cells in Patients with B Cell Leukemia |
| Q48336884 | Is the Genetic Background of Co-Stimulatory CD28/CTLA-4 Pathway the Risk Factor for Prostate Cancer? |
| Q34754748 | It's all Rel-ative: NF-kappaB and CD28 costimulation of T-cell activation. |
| Q33755007 | Linked tumor-selective virus replication and transgene expression from E3-containing oncolytic adenoviruses |
| Q36189902 | Lymphocyte Activation Dynamics Is Shaped by Hereditary Components at Chromosome Region 17q12-q21 |
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| Q36494214 | Modification of accessory molecule signaling |
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| Q30845162 | Modulation of NKT cell development by B7-CD28 interaction: an expanding horizon for costimulation |
| Q36376714 | Modulation of T-Cell Costimulation as Immunotherapy or Immunochemotherapy in Experimental Visceral Leishmaniasis |
| Q36033294 | Molecular mechanisms of glucocorticoids in the control of inflammation and lymphocyte apoptosis |
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| Q39273543 | Nanobody-induced perturbation of LFA-1/L-plastin phosphorylation impairs MTOC docking, immune synapse formation and T cell activation |
| Q35146722 | Negative T cell costimulation and islet tolerance. |
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