review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1036147451 |
P356 | DOI | 10.1007/S00115-007-2261-9 |
P698 | PubMed publication ID | 17551708 |
P50 | author | Sven G Meuth | Q88461559 |
Heinz Wiendl | Q27583547 | ||
Christoph Kleinschnitz | Q67221107 | ||
P2093 | author name string | B C Kieseier | |
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Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412 | Q29622893 | ||
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CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris | Q33855058 | ||
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Update on the therapeutic potential of PDE4 inhibitors | Q34107488 | ||
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Treatment of multiple sclerosis with the pregnancy hormone estriol | Q34151750 | ||
Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches | Q34156542 | ||
Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation | Q34178136 | ||
Role of costimulatory molecules in autoimmunity. | Q34233359 | ||
High-dose immunosuppressive therapy and autologous peripheral blood stem cell transplantation for severe multiple sclerosis | Q34237823 | ||
Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators | Q34322193 | ||
Pixantrone (BBR2778): a new immunosuppressant in multiple sclerosis with a low cardiotoxicity | Q34334271 | ||
Autoimmunity provoked by infection: how good is the case for T cell epitope mimicry? | Q34348969 | ||
Treatment with laquinimod reduces development of active MRI lesions in relapsing MS. | Q34405210 | ||
Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity | Q34448370 | ||
The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses | Q34468846 | ||
Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon beta | Q34514715 | ||
Activation and inhibition of lymphocytes by costimulation | Q34517906 | ||
The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses | Q34542227 | ||
Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial | Q34543217 | ||
Oral fingolimod (FTY720) for relapsing multiple sclerosis | Q34565985 | ||
Regulatory CD56(bright) natural killer cells mediate immunomodulatory effects of IL-2Ralpha-targeted therapy (daclizumab) in multiple sclerosis. | Q34596171 | ||
Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases. | Q34710256 | ||
Therapeutic approaches in multiple sclerosis: lessons from failed and interrupted treatment trials | Q34725775 | ||
BX-471 Berlex | Q34757500 | ||
Neurotrophic cross-talk between the nervous and immune systems: implications for neurological diseases | Q35071710 | ||
Sirolimus: its discovery, biological properties, and mechanism of action | Q35125746 | ||
Chemokines and matrix metalloproteinase-9 in leukocyte recruitment to the central nervous system. | Q35196338 | ||
Sensory neuron-specific sodium channel SNS is abnormally expressed in the brains of mice with experimental allergic encephalomyelitis and humans with multiple sclerosis | Q35325861 | ||
Peroxisome proliferator-activated receptor-gamma: therapeutic target for diseases beyond diabetes: quo vadis? | Q35688221 | ||
Lessons learned from anti-CD40L treatment in systemic lupus erythematosus patients | Q35824531 | ||
Mycophenolate mofetil in multiple sclerosis | Q35835852 | ||
Erythropoietin as a novel neuroprotectant. | Q35844687 | ||
Autoimmune concepts of multiple sclerosis as a basis for selective immunotherapy: from pipe dreams to (therapeutic) pipelines | Q35861182 | ||
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Na+ channel expression along axons in multiple sclerosis and its models | Q35921669 | ||
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A single amino acid change in a myelin basic protein peptide confers the capacity to prevent rather than induce experimental autoimmune encephalomyelitis | Q37611832 | ||
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Macrophages in T cell line-mediated, demyelinating, and chronic relapsing experimental autoimmune encephalomyelitis in Lewis rats | Q41348774 | ||
Human T cell autoimmunity against myelin basic protein: CD4+ cells recognizing epitopes of the T cell receptor beta chain from a myelin basic protein-specific T cell clone. | Q41577458 | ||
A phase I trial of solubilized DR2:MBP84-102 (AG284) in multiple sclerosis | Q41728578 | ||
Identification of Epstein-Barr virus proteins as putative targets of the immune response in multiple sclerosis | Q41788436 | ||
Myeloablative and immunosuppressive properties of treosulfan in mice | Q42168522 | ||
TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs | Q42181372 | ||
T cell vaccination in multiple sclerosis patients with autologous CSF-derived activated T cells: results from a pilot study | Q42692324 | ||
Suppressor T cells in human diseases | Q42971257 | ||
Autologous hematopoietic stem cell transplantation suppresses Gd-enhanced MRI activity in MS. | Q43668453 | ||
Multiple sclerosis: altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage | Q43708042 | ||
Mycophenolate-mofetil in the treatment of refractory multiple sclerosis. | Q43746298 | ||
Vaccination against experimental allergic encephalomyelitis with T cell receptor peptides | Q43794379 | ||
First human trial of FTY720, a novel immunomodulator, in stable renal transplant patients | Q43931513 | ||
The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease | Q43934617 | ||
Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis | Q44002202 | ||
The new orally active immunoregulator laquinimod (ABR-215062) effectively inhibits development and relapses of experimental autoimmune encephalomyelitis | Q44133715 | ||
Statins as immunomodulators: comparison with interferon-beta 1b in MS. | Q44172256 | ||
The effect of the neuroprotective agent riluzole on MRI parameters in primary progressive multiple sclerosis: a pilot study | Q44244034 | ||
Peroxisome proliferator-activated receptor gamma thiazolidinedione agonists increase glucose metabolism in astrocytes | Q44251886 | ||
Matrix metalloproteinases in the normal human central nervous system, microglial nodules, and multiple sclerosis lesions | Q44310002 | ||
Amelioration of experimental autoimmune encephalomyelitis in Lewis rats by FTY720 treatment | Q44370378 | ||
Abnormal sodium channel distribution in optic nerve axons in a model of inflammatory demyelination | Q44477086 | ||
Cladribine in treatment of chronic progressive multiple sclerosis | Q44496335 | ||
Cannabinoids inhibit neurodegeneration in models of multiple sclerosis | Q44522438 | ||
Phenytoin protects spinal cord axons and preserves axonal conduction and neurological function in a model of neuroinflammation in vivo | Q44540512 | ||
Action of treosulfan in myelin-oligodendrocyte-glycoprotein-induced experimental autoimmune encephalomyelitis and human lymphocytes | Q44641631 | ||
Exploitation of the Vbeta8.2 T cell receptor in protection against experimental autoimmune encephalomyelitis using a live vaccinia virus vector | Q44779663 | ||
Circulating CD4+CD25+ T regulatory cells are not altered in multiple sclerosis and unaffected by disease-modulating drugs | Q44801480 | ||
Synthesis and biological evaluation of new 1,2-dihydro-4-hydroxy-2-oxo-3-quinolinecarboxamides for treatment of autoimmune disorders: structure-activity relationship | Q44823676 | ||
Axonal protection using flecainide in experimental autoimmune encephalomyelitis. | Q44880213 | ||
Minocycline reduces gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis. | Q44880234 | ||
Oral simvastatin treatment in relapsing-remitting multiple sclerosis | Q44897670 | ||
Calcium channel blockers ameliorate disease in a mouse model of multiple sclerosis | Q45008706 | ||
Modulation of effector cell functions in experimental autoimmune encephalomyelitis by leflunomide--mechanisms independent of pyrimidine depletion | Q45029733 | ||
Sodium channels contribute to microglia/macrophage activation and function in EAE and MS. | Q45076768 | ||
Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life | Q45152665 | ||
The immunomodulator FTY720 interferes with effector functions of human monocyte-derived dendritic cells. | Q45229482 | ||
Peroxisome proliferator-activated receptor-gamma agonists inhibit the activation of microglia and astrocytes: implications for multiple sclerosis | Q45303266 | ||
Epstein-Barr virus and multiple sclerosis: evidence of association from a prospective study with long-term follow-up | Q45417845 | ||
Intrathecal B-cell clonal expansion, an early sign of humoral immunity, in the cerebrospinal fluid of patients with clinically isolated syndrome suggestive of multiple sclerosis | Q46266579 | ||
Lipoic acid in multiple sclerosis: a pilot study | Q46407394 | ||
Erythropoietin decreases cytotoxicity and nitric oxide formation induced by inflammatory stimuli in rat oligodendrocytes | Q46460140 | ||
Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention | Q46499427 | ||
Erythropoietin: novel approaches to neuroprotection in human brain disease | Q35956310 | ||
The promise of minocycline in neurology. | Q35958974 | ||
Autologous haematopoietic-stem-cell transplantation for multiple sclerosis | Q35994389 | ||
Other therapy options and future strategies for treating patients with multiple sclerosis | Q35995796 | ||
Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs | Q36072414 | ||
Therapeutic strategies to prevent neurodegeneration and promote regeneration in multiple sclerosis. | Q36074419 | ||
Therapeutic blockade of TCR signal transduction and co-stimulation in autoimmune disease | Q36107645 | ||
Blocking adhesion molecules as therapy for multiple sclerosis: natalizumab | Q36148448 | ||
The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms | Q36205278 | ||
Therapeutic targeting of alpha 4-integrins in chronic inflammatory diseases: tipping the scales of risk towards benefit? | Q36211855 | ||
Intense T cell depletion followed by autologous bone marrow transplantation for severe multiple sclerosis | Q36226307 | ||
CTLA-4 is a second receptor for the B cell activation antigen B7 | Q36230356 | ||
Natalizumab for the treatment of multiple sclerosis and Crohn's disease | Q36284072 | ||
Cladribine for multiple sclerosis: review and current status | Q36307847 | ||
Granulocyte colony-stimulating factor: a novel mediator of T cell tolerance | Q36318980 | ||
Antigen-specific therapies in multiple sclerosis. | Q36327373 | ||
Antigen-specific therapies in multiple sclerosis: going beyond proteins and peptides | Q36327377 | ||
Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction | Q36368672 | ||
Promotion of remyelination by immunoglobulins: implications for the treatment of multiple sclerosis | Q36384922 | ||
Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients. | Q36402704 | ||
Lymphoid neogenesis in chronic inflammatory diseases. | Q36405080 | ||
Multiple sclerosis--the plaque and its pathogenesis | Q36410882 | ||
Mycophenolate mofetil and tacrolimus: new therapeutic options in neuroimmunological diseases | Q36438898 | ||
The value of animal models for drug development in multiple sclerosis. | Q36458937 | ||
T cell vaccination induces T cell receptor Vbeta-specific Qa-1-restricted regulatory CD8(+) T cells | Q36475992 | ||
Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro | Q37126896 | ||
Effective combination of minocycline and interferon-beta in a model of multiple sclerosis | Q46548808 | ||
Graft-versus-host disease prevention by rapamycin: cellular mechanisms | Q46600793 | ||
Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients | Q46740179 | ||
The effect of anti-alpha4 integrin antibody on brain lesion activity in MS. The UK Antegren Study Group | Q48135012 | ||
Phase I study of a humanized anti-CD11/CD18 monoclonal antibody in multiple sclerosis | Q48383559 | ||
A controlled trial of natalizumab for relapsing multiple sclerosis | Q48414534 | ||
Prevention of experimental autoimmune encephalomyelitis in common marmosets using an anti-IL-12p40 monoclonal antibody | Q48442189 | ||
Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis | Q48475566 | ||
Oral fumaric acid esters for the treatment of active multiple sclerosis: an open-label, baseline-controlled pilot study | Q48488976 | ||
A Phase II study of the safety and efficacy of teriflunomide in multiple sclerosis with relapses | Q48602930 | ||
Antibody-mediated suppression of Vbeta5.2/5.3(+) T cells in multiple sclerosis: results from an MRI-monitored phase II clinical trial | Q48647481 | ||
MK-801 limits neurovascular dysfunction during experimental allergic encephalomyelitis | Q48671716 | ||
Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2. | Q48851709 | ||
A phase II trial of anti-CD4 antibodies in the treatment of multiple sclerosis. | Q48967659 | ||
Microglial expression of the B7 family member B7 homolog 1 confers strong immune inhibition: implications for immune responses and autoimmunity in the CNS. | Q48974951 | ||
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis. | Q49014751 | ||
Double-Blind Pilot Trial of Oral Tolerization with Myelin Antigens in Multiple Sclerosis | Q50127386 | ||
T cell vaccination in multiple sclerosis relapsing-remitting nonresponders patients. | Q50749623 | ||
Hormonal treatment with sex steroids in women is associated with lower p105 serum concentrations. | Q50930145 | ||
Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis. | Q51027456 | ||
The effect of cladribine on T(1) 'black hole' changes in progressive MS. | Q53909697 | ||
Biological assessment and MRI monitoring of the therapeutic efficacy of a monoclonal anti-T CD4 antibody in multiple sclerosis patients. | Q53991755 | ||
Beneficial effect of erythropoietin on experimental allergic encephalomyelitis. | Q54128490 | ||
Immunity to TCR peptides in multiple sclerosis. I. Successful immunization of patients with synthetic V beta 5.2 and V beta 6.1 CDR2 peptides. | Q54481809 | ||
The gelatinase inhibitory activity of tetracyclines and chemically modified tetracycline analogues as measured by a novel microtiter assay for inhibitors. | Q54585384 | ||
Induction of granulocyte colony-stimulating factor mRNA by focal cerebral ischemia and cortical spreading depression. | Q54694225 | ||
Natalizumab effects on immune cell responses in multiple sclerosis | Q57041915 | ||
Do myelin-directed antibodies predict multiple sclerosis? | Q57042143 | ||
Modified anti-CD3 therapy in psoriatic arthritis: a phase I/II clinical trial | Q57101760 | ||
Mechanisms of axonal dysfunction after spinal cord injury: with an emphasis on the role of voltage-gated potassium channels | Q57839822 | ||
Cladribine and progressive MS: Clinical and MRI outcomes of a multicenter controlled trial | Q57911989 | ||
Induction of a non-encephalitogenic type 2 T helper-cell autoimmune responsein multiple sclerosis after administration of an altered peptide ligand ina placebo-controlled, randomized phase II trial | Q57911995 | ||
Cytokine production and surface marker expression in acute and stable multiple sclerosis: altered IL-12 production and augmented signaling lymphocytic activation molecule (SLAM)-expressing lymphocytes in acute multiple sclerosis | Q57997698 | ||
Anti-myelin antibodies do not allow earlier diagnosis of multiple sclerosis | Q59273850 | ||
Glutamate excitotoxicity in a model of multiple sclerosis | Q60450917 | ||
Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange | Q61709608 | ||
Selective and antigen-dependent effects of myelin degeneration on central nervous system inflammation | Q61709613 | ||
Multiple sclerosis: trapped in deadly glue | Q61853106 | ||
P433 | issue | 8 | |
P921 | main subject | immunotherapy | Q1427096 |
multiple sclerosis | Q8277 | ||
P304 | page(s) | 883-911 | |
P577 | publication date | 2007-08-01 | |
P1433 | published in | Der Nervenarzt | Q15446312 |
P1476 | title | [Update on pathophysiologic and immunotherapeutic approaches for the treatment of multiple sclerosis] | |
P478 | volume | 78 |
Q51958899 | [Targeting B cells in multiple sclerosis. Current concepts and strategies]. | cites work | P2860 |
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