Nε-lysine acetylation of a bacterial transcription factor inhibits Its DNA-binding activity

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Nε-lysine acetylation of a bacterial transcription factor inhibits Its DNA-binding activity is …
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scholarly articleQ13442814

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P819ADS bibcode2010PLoSO...515123T
P356DOI10.1371/JOURNAL.PONE.0015123
P3181OpenCitations bibliographic resource ID4178515
P932PMC publication ID3013089
P698PubMed publication ID21217812
P5875ResearchGate publication ID49739564

P2093author name stringHeng Zhu
Jorge C Escalante-Semerena
Chien-Sheng Chen
Sandy Thao
P2860cites workRcsCDB His-Asp phosphorelay system negatively regulates the flhDC operon in Escherichia coli.Q54521795
Regulation of Escherichia coli cell division genes ftsA and ftsZ by the two-component system rcsC-rcsBQ73189459
Positive control of the two-component RcsC/B signal transduction network by DjlA: a member of the DnaJ family of molecular chaperones in Escherichia coliQ73866641
Structures of Mycobacterium tuberculosis DosR and DosR-DNA complex involved in gene activation during adaptation to hypoxic latencyQ81396757
Acetyl phosphate-sensitive regulation of flagellar biogenesis and capsular biosynthesis depends on the Rcs phosphorelayQ83999384
Protein microarrays: potentials and limitationsQ22241270
Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylationQ24534597
A previously undescribed pathway for pyrimidine catabolismQ24546368
Acetylation of histones and transcription-related factorsQ24548503
Crystal structure of GerE, the ultimate transcriptional regulator of spore formation in Bacillus subtilisQ27630479
Structure of a Sir2 substrate, Alba, reveals a mechanism for deacetylation-induced enhancement of DNA bindingQ27641130
Structural Analysis of the DNA-binding Domain of theErwinia amylovora RcsB Protein and Its Interaction with the RcsAB BoxQ27641203
Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoterQ27860697
A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.Q27931475
Release of proteins and peptides from fusion proteins using a recombinant plant virus proteinaseQ28253169
Acetylation of non-histone proteins modulates cellular signalling at multiple levelsQ28294575
Structure and functions of the GNAT superfamily of acetyltransferasesQ28296840
Global analysis of protein phosphorylation in yeastQ29615057
Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic fluxQ29615102
Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological researchQ29619122
Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysineQ30876890
Identification of the protein acetyltransferase (Pat) enzyme that acetylates acetyl-CoA synthetase in Salmonella entericaQ31088928
The Sir 2 family of protein deacetylasesQ33222287
N-lysine propionylation controls the activity of propionyl-CoA synthetaseQ33293490
A proteome chip approach reveals new DNA damage recognition activities in Escherichia coliQ33310596
DksA and ppGpp directly regulate transcription of the Escherichia coli flagellar cascadeQ33590521
Regulation of osmC gene expression by the two-component system rcsB-rcsC in Escherichia coliQ34011916
Ribosomal protein S4 is a transcription factor with properties remarkably similar to NusA, a protein involved in both non-ribosomal and ribosomal RNA antitermination.Q34080715
A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response.Q34433751
Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptorQ34698474
NhaR and RcsB independently regulate the osmCp1 promoter of Escherichia coli at overlapping regulatory sitesQ35162060
Isolation and characterization of rcsB mutations that affect colanic acid capsule synthesis in Escherichia coli K-12Q35625657
Inactivation of mdoH leads to increased expression of colanic acid capsular polysaccharide in Escherichia coliQ35632109
A combined approach to improving large-scale production of tobacco etch virus proteaseQ36101845
Fine-structure mapping and identification of two regulators of capsule synthesis in Escherichia coli K-12.Q36204735
Capsule synthesis in Escherichia coli K-12 is regulated by proteolysisQ36230246
The Rcs phosphorelay: a complex signal transduction systemQ36253588
The role of the Rcs phosphorelay in EnterobacteriaceaeQ36374373
Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coliQ37080670
Structural and functional analysis of the C-terminal DNA binding domain of the Salmonella typhimurium SPI-2 response regulator SsrB.Q37169461
Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesisQ37227239
The diversity of lysine-acetylated proteins in Escherichia coliQ38498432
Construction and use of new cloning vectors for the rapid isolation of recombinant proteins from Escherichia coli.Q38521352
A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylationQ40097842
CobB regulates Escherichia coli chemotaxis by deacetylating the response regulator CheY.Q40960311
Sir2 and the acetyltransferase, Pat, regulate the archaeal chromatin protein, AlbaQ42653218
Interaction of the regulator proteins RcsA and RcsB with the promoter of the operon for amylovoran biosynthesis in Erwinia amylovora.Q42665576
Acetylation represses the binding of CheY to its target proteinsQ43096475
Genetically encoding N(epsilon)-acetyllysine in recombinant proteins.Q46751659
Escherichia coli transcription factor YncC (McbR) regulates colanic acid and biofilm formation by repressing expression of periplasmic protein YbiM (McbA).Q47879002
Identification of an RcsA/RcsB recognition motif in the promoters of exopolysaccharide biosynthetic operons from Erwinia amylovora and Pantoea stewartii subspecies stewartiiQ47992114
The RcsAB box. Characterization of a new operator essential for the regulation of exopolysaccharide biosynthesis in enteric bacteriaQ50122219
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageQuantQ112270642
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)e15123
P577publication date2010-12-31
P1433published inPLOS OneQ564954
P1476titleNε-lysine acetylation of a bacterial transcription factor inhibits Its DNA-binding activity
P478volume5

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cites work (P2860)
Q42013117A positive selection approach identifies residues important for folding of Salmonella enterica Pat, an N(ε)-lysine acetyltransferase that regulates central metabolism enzymes
Q38958836Acetate metabolism regulation in Escherichia coli: carbon overflow, pathogenicity, and beyond.
Q42094089Acetoacetyl-CoA synthetase activity is controlled by a protein acetyltransferase with unique domain organization in Streptomyces lividans
Q35946161Acetylation of Lysine 201 Inhibits the DNA-Binding Ability of PhoP to Regulate Salmonella Virulence
Q37125410Acetylation of the response regulator RcsB controls transcription from a small RNA promoter
Q35320756Acetylation regulates the stability of a bacterial protein: growth stage-dependent modification of RNase R.
Q26801091Acylation of Biomolecules in Prokaryotes: a Widespread Strategy for the Control of Biological Function and Metabolic Stress
Q41827709Alternate deacylating specificities of the archaeal sirtuins Sir2Af1 and Sir2Af2.
Q47796664Alternative sigma factor RpoN and its modulation protein YhbH are indispensable for Erwinia amylovora virulence.
Q27683358Atypical OmpR/PhoB Subfamily Response Regulator GlnR of Actinomycetes Functions as a Homodimer, Stabilized by the Unphosphorylated Conserved Asp-focused Charge Interactions
Q48031442Biochemical Characterization of the Lysine Acetylation of Tyrosyl-tRNA Synthetase in Escherichia coli.
Q35370523Biochemical and thermodynamic analyses of Salmonella enterica Pat, a multidomain, multimeric N(ε)-lysine acetyltransferase involved in carbon and energy metabolism
Q47397014Conformational dynamism for DNA interaction in the Salmonella RcsB response regulator.
Q86506982Conserved aspartate and lysine residues of RcsB are required for amylovoran biosynthesis, virulence, and DNA binding in Erwinia amylovora
Q34809835Control of protein function by reversible Nɛ-lysine acetylation in bacteria
Q41693951Deacetylation of topoisomerase I is an important physiological function of E. coli CobB.
Q42382046Deciphering the Regulatory Circuitry That Controls Reversible Lysine Acetylation in Salmonella enterica
Q37983986Designer proteins: applications of genetic code expansion in cell biology
Q64259865Designing and Engineering AM1 for Itaconic Acid Production
Q35566272Differential lysine acetylation profiles of Erwinia amylovora strains revealed by proteomics
Q92479384Dynamic Characterization of Protein and Posttranslational Modification Levels in Mycobacterial Cholesterol Catabolism
Q26774700Elucidating Host-Pathogen Interactions Based on Post-Translational Modifications Using Proteomics Approaches
Q35179640Exposure to Glycolytic Carbon Sources Reveals a Novel Layer of Regulation for the MalT Regulon
Q27025953Functional protein microarray as molecular decathlete: a versatile player in clinical proteomics
Q26999463Genetic code expansion as a tool to study regulatory processes of transcription
Q43590820Genetically encoding thioacetyl-lysine as a non-deacetylatable analog of lysine acetylation in Escherichia coli.
Q34572484Genomic analysis of the regulatory elements and links with intrinsic DNA structural properties in the shrunken genome of Buchnera
Q42362552Glucose Induces ECF Sigma Factor Genes, sigX and sigM, Independent of Cognate Anti-sigma Factors through Acetylation of CshA in Bacillus subtilis
Q57798560Identification of Novel Protein Lysine Acetyltransferases in Escherichia coli
Q34099056Identification of lactoferricin B intracellular targets using an Escherichia coli proteome chip
Q41766402In Salmonella enterica, the sirtuin-dependent protein acylation/deacylation system (SDPADS) maintains energy homeostasis during growth on low concentrations of acetate
Q36234801Inhibition of acetyl phosphate-dependent transcription by an acetylatable lysine on RNA polymerase
Q38294952Interaction of the RcsB Response Regulator with Auxiliary Transcription Regulators in Escherichia coli
Q34056806Intracellular concentrations of 65 species of transcription factors with known regulatory functions in Escherichia coli
Q35558005Isolation and Characterization of Acetylated Derivative of Recombinant Insulin Lispro Produced in Escherichia coli
Q57066430Lysine Acetylation Regulates Alanyl-tRNA Synthetase Activity in
Q92864283Lysine acetylation of the housekeeping sigma factor enhances the activity of the RNA polymerase holoenzyme
Q48316779Lysine acetylation regulates the function of the global anaerobic transcription factor FnrL in Rhodobacter sphaeroides.
Q36575096Multiple Posttranslational Modifications of Leptospira biflexa Proteins as Revealed by Proteomic Analysis
Q46271225New Insights into the Non-orthodox Two Component Rcs Phosphorelay System
Q40827378Nonenzymatic Protein Acetylation Detected by NAPPA Protein Arrays
Q42691239Nε- and O-Acetylation in Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains: Proteins Involved in Bioenergetics, Virulence, and Antimicrobial Resistance Are Acetylated.
Q26830244Overview of protein microarrays
Q36099783PanM, an acetyl-coenzyme A sensor required for maturation of L-aspartate decarboxylase (PanD).
Q92239138Post-translational Protein Acetylation: An Elegant Mechanism for Bacteria to Dynamically Regulate Metabolic Functions
Q37160425Post-translational Serine/Threonine Phosphorylation and Lysine Acetylation: A Novel Regulatory Aspect of the Global Nitrogen Response Regulator GlnR in S. coelicolor M145.
Q55454391Post-translational regulation of a Porphyromonas gingivalis regulator.
Q34983997Profiling the dynamics of a human phosphorylome reveals new components in HGF/c-Met signaling.
Q54332700Prokaryotic Nε-lysine acetylomes and implications for new antibiotics.
Q26851625Prokaryotic genome regulation: a revolutionary paradigm
Q40062098Protein Acetylation Is Involved in Salmonella enterica Serovar Typhimurium Virulence
Q53699174Protein Acetylation Mediated by YfiQ and CobB Is Involved in the Virulence and Stress Response of Yersinia pestis.
Q92040656Protein Acetylation in Bacteria
Q38302162Protein acetylation affects acetate metabolism, motility and acid stress response in Escherichia coli
Q52727532Protein acetylation and butyrylation regulate the phenotype and metabolic shifts of the endospore-forming Clostridium acetobutylicum.
Q98778842Protein acetylation and deacetylation: An important regulatory modification in gene transcription (Review)
Q42684891Protein acetylation dynamics in response to carbon overflow in Escherichia coli
Q37889858Protein acetylation in prokaryotes
Q41811914Protein acetylation in prokaryotes increases stress resistance
Q47558014Protein acetylation: an important mechanism in actinobacteria.
Q38590397Protein lysine acetylation in bacteria: Current state of the art.
Q93107143Protein post-translational modifications in bacteria
Q47331651Recent Advances in Substrate Identification of Protein Kinases in Plants and Their Role in Stress Management
Q38386655Regulation of a Protein Acetyltransferase in Myxococcus xanthus by the Coenzyme NADP.
Q38691364Regulation, Function, and Detection of Protein Acetylation in Bacteria
Q37197388Reversible acetylation regulates acetate and propionate metabolism in Mycobacterium smegmatis
Q37147957Reversible lysine acetylation is involved in DNA replication initiation by regulating activities of initiator DnaA in Escherichia coli
Q45376320Reversibly acetylated lysine residues play important roles in the enzymatic activity of Escherichia coli N-hydroxyarylamine O-acetyltransferase
Q57459051Small-Molecule Acetylation Controls the Degradation of Benzoate and Photosynthesis in Rhodopseudomonas palustris
Q52371961Structural Basis for DNA Recognition by the Two-Component Response Regulator RcsB.
Q27683517Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation
Q50664922Studying the Lysine Acetylation of Malate Dehydrogenase.
Q35939782System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases.
Q36210860The Bacterial Two-Hybrid System Uncovers the Involvement of Acetylation in Regulating of Lrp Activity in Salmonella Typhimurium
Q35106207The E. coli sirtuin CobB shows no preference for enzymatic and nonenzymatic lysine acetylation substrate sites
Q49627247The Global Acetylome of the Human Pathogen Vibrio cholerae V52 Reveals Lysine Acetylation of Major Transcriptional Regulators
Q35398904The Porphyromonas gingivalis ferric uptake regulator orthologue binds hemin and regulates hemin-responsive biofilm development.
Q38850956The acetylation motif in AMP-forming Acyl coenzyme A synthetases contains residues critical for acetylation and recognition by the protein acetyltransferase pat of Rhodopseudomonas palustris
Q41993813The missing link in coenzyme A biosynthesis: PanM (formerly YhhK), a yeast GCN5 acetyltransferase homologue triggers aspartate decarboxylase (PanD) maturation in Salmonella enterica
Q49964101The protein acyltransferase Pat post-transcriptionally controls HilD to repress Salmonella invasion
Q42837165The role of activated acetate intermediates in the control of Escherichia coli biofilm amounts
Q60301358The spermidine acetyltransferase SpeG regulates transcription of the small RNA rprA

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