scholarly article | Q13442814 |
P50 | author | Peter Dedon | Q30069658 |
Siew Pheng Lim | Q57286090 | ||
Pei-Yong Shi | Q59435668 | ||
Fabian Hia | Q62747556 | ||
Shee-Mei Lok | Q89723065 | ||
Hongping Dong | Q114420607 | ||
Petra Kukkaro | Q115165141 | ||
P2093 | author name string | David C Chang | |
Yie Hou Lee | |||
Yok Hian Chionh | |||
Maggie Ho Chia Hua | |||
P2860 | cites work | Induction of sporulation in Saccharomyces cerevisiae leads to the formation of N6-methyladenosine in mRNA: a potential mechanism for the activity of the IME4 gene | Q24537653 |
Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells | Q24563918 | ||
Yeast targets for mRNA methylation | Q24610628 | ||
Inhibition of interferon signaling by dengue virus | Q24630622 | ||
The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids | Q27469354 | ||
Inhibition of Alpha/Beta Interferon Signaling by the NS4B Protein of Flaviviruses | Q27469841 | ||
An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization | Q27472613 | ||
Mutations in the Yellow Fever Virus Nonstructural Protein NS2A Selectively Block Production of Infectious Particles | Q27472873 | ||
Infectious cDNA clone of the epidemic west nile virus from New York City | Q27472878 | ||
Triaryl pyrazoline compound inhibits flavivirus RNA replication | Q27473130 | ||
West Nile Virus 5'-Cap Structure Is Formed by Sequential Guanine N-7 and Ribose 2'-O Methylations by Nonstructural Protein 5 | Q27477465 | ||
Molecular and Functional Analyses of Kunjin Virus Infectious cDNA Clones Demonstrate the Essential Roles for NS2A in Virus Assembly and for a Nonconservative Residue in NS3 in RNA Replication | Q27477562 | ||
Structure and Function of Flavivirus NS5 Methyltransferase | Q27478377 | ||
Distinct RNA Elements Confer Specificity to Flavivirus RNA Cap Methylation Events | Q27480347 | ||
Functional Analysis of Mosquito-Borne Flavivirus Conserved Sequence Elements within 3' Untranslated Region of West Nile Virus by Use of a Reporting Replicon That Differentiates between Viral Translation and RNA Replication | Q27485398 | ||
West Nile Virus Methyltransferase Catalyzes Two Methylations of the Viral RNA Cap through a Substrate-Repositioning Mechanism | Q27485750 | ||
Deletion analysis of dengue virus type 4 nonstructural protein NS2B: identification of a domain required for NS2B-NS3 protease activity | Q27486196 | ||
Processing of the yellow fever virus nonstructural polyprotein: a catalytically active NS3 proteinase domain and NS2B are required for cleavages at dibasic sites | Q27486606 | ||
Cyclosporine Inhibits Flavivirus Replication through Blocking the Interaction between Host Cyclophilins and Viral NS5 Protein | Q27488982 | ||
The 1.85 A structure of vaccinia protein VP39: a bifunctional enzyme that participates in the modification of both mRNA ends | Q27732664 | ||
Structural basis for sequence-nonspecific recognition of 5'-capped mRNA by a cap-modifying enzyme | Q27760566 | ||
The methylated constituents of L cell messenger RNA: evidence for an unusual cluster at the 5' terminus | Q28202411 | ||
5′-Terminal structures of poly(A)+ cytoplasmic messenger RNA and of poly(A)+ and poly(A)− heterogeneous nuclear RNA of cells of the dipteran Drosophila melanogaster | Q28237586 | ||
Recombinant dengue type 1 virus NS5 protein expressed in Escherichia coli exhibits RNA-dependent RNA polymerase activity | Q28276481 | ||
5'-Terminal and internal methylated nucleotide sequences in HeLa cell mRNA | Q28300148 | ||
2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members | Q28513232 | ||
Association between NS3 and NS5 Proteins of Dengue Virus Type 2 in the Putative RNA Replicase Is Linked to Differential Phosphorylation of NS5 | Q29619933 | ||
Inhibition of interferon signaling by the New York 99 strain and Kunjin subtype of West Nile virus involves blockage of STAT1 and STAT2 activation by nonstructural proteins | Q29620712 | ||
West Nile virus inhibits the signal transduction pathway of alpha interferon | Q33718537 | ||
Posttranscriptional modifications in 16S and 23S rRNAs of the archaeal hyperthermophile Sulfolobus solfataricus | Q33731377 | ||
Regulation of pre-mRNA splicing in Xenopus oocytes by targeted 2'-O-methylation | Q33799108 | ||
RNA modifications: a mechanism that modulates gene expression | Q34132194 | ||
Active site in RrmJ, a heat shock-induced methyltransferase | Q34144691 | ||
Functional analysis of two cavities in flavivirus NS5 polymerase | Q34800273 | ||
Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5. | Q35239001 | ||
N6-methyladenosine residues in an intron-specific region of prolactin pre-mRNA. | Q36722908 | ||
5'-Terminal and internal methylated nucleosides in herpes simplex virus type 1 mRNA. | Q37506500 | ||
Biochemical and genetic characterization of dengue virus methyltransferase | Q38975991 | ||
Sequence specificity of internal methylation in B77 avian sarcoma virus RNA subunits | Q40046945 | ||
Identification and mapping of N6-methyladenosine containing sequences in Simian Virus 40 RNA | Q40240837 | ||
De novo synthesis of RNA by the dengue virus RNA-dependent RNA polymerase exhibits temperature dependence at the initiation but not elongation phase | Q40596948 | ||
The importance of being modified: roles of modified nucleosides and Mg2+ in RNA structure and function. | Q40998399 | ||
The NS 3 nonstructural protein of flaviviruses contains an RNA triphosphatase activity | Q41517814 | ||
The carboxy-terminal part of the NS 3 protein of the West Nile Flavivirus can be isolated as a soluble protein after proteolytic cleavage and represents an RNA-stimulated NTPase | Q42985863 | ||
Inhibition of 6-methyladenine formation decreases the translation efficiency of dihydrofolate reductase transcripts. | Q54079522 | ||
N-6-methyl-adenosine in adenovirus type 2 nuclear RNA is conserved in the formation of messenger RNA | Q64382037 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Dengue virus | Q476209 |
Flaviviridae | Q1331256 | ||
dengue virus protein NS5 | Q114698643 | ||
P304 | page(s) | e1002642 | |
P577 | publication date | 2012-01-01 | |
P1433 | published in | PLOS Pathogens | Q283209 |
P1476 | title | 2'-O methylation of internal adenosine by flavivirus NS5 methyltransferase | |
P478 | volume | 8 |
Q115216139 | A conserved arginine in NS5 binds genomic 3' stem-loop RNA for primer-independent initiation of flavivirus RNA replication |
Q37197864 | A multidimensional platform for the purification of non-coding RNA species |
Q38218106 | A new paradigm: innate immune sensing of viruses via the unfolded protein response |
Q38866173 | An Overview of Current Approaches Toward the Treatment and Prevention of West Nile Virus Infection |
Q104566578 | An epigenetic "extreme makeover": the methylation of flaviviral RNA (and beyond) |
Q40403939 | Binding of the Methyl Donor S-Adenosyl-l-Methionine to Middle East Respiratory Syndrome Coronavirus 2'-O-Methyltransferase nsp16 Promotes Recruitment of the Allosteric Activator nsp10. |
Q47558465 | Characterization of a candidate tetravalent vaccine based on 2'-O-methyltransferase mutants |
Q35487910 | Characterization of dengue virus NS4A and NS4B protein interaction |
Q40211835 | Construction of plasmid, bacterial expression, purification, and assay of dengue virus type 2 NS5 methyltransferase |
Q89920678 | Crosstalk between RNA Metabolism and Cellular Stress Responses during Zika Virus Replication |
Q27695629 | Crystal structure of dengue virus methyltransferase without S-adenosyl-L-methionine |
Q35760466 | Determinants of Dengue Virus NS4A Protein Oligomerization |
Q37643762 | Dimerization of flavivirus NS4B protein |
Q27486503 | Dynamics of Human and Viral RNA Methylation during Zika Virus Infection |
Q33570165 | Dysregulated sphingolipid metabolism in endometriosis |
Q38742066 | Evasion of early innate immune response by 2'-O-methylation of dengue genomic RNA. |
Q90971072 | FTSJ3 is an RNA 2'-O-methyltransferase recruited by HIV to avoid innate immune sensing |
Q38184248 | Flavivirus RNA methylation |
Q38289956 | Flavivirus reverse genetic systems, construction techniques and applications: a historical perspective |
Q40037886 | Functional RNA during Zika virus infection |
Q39255013 | Generation and characterization of mouse monoclonal antibodies against NS4B protein of dengue virus |
Q26700125 | Identification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus Methyltransferase |
Q47166784 | Identification of Key Genes in Colorectal Cancer Regulated by miR-34a. |
Q37408421 | Identification of RNase L-dependent, 3'-end-modified, viral small RNAs in Sindbis virus-infected mammalian cells |
Q47559131 | In vitro methods for testing antiviral drugs |
Q34240105 | Innate immunity to dengue virus infection and subversion of antiviral responses |
Q60931107 | Lifestyle modifications: coordinating the tRNA epitranscriptome with codon bias to adapt translation during stress responses |
Q27316483 | Live Cell Analysis and Mathematical Modeling Identify Determinants of Attenuation of Dengue Virus 2'-O-Methylation Mutant |
Q35488254 | Mapping the Interactions between the NS4B and NS3 proteins of dengue virus |
Q27676369 | Membrane Topology and Function of Dengue Virus NS2A Protein |
Q47107616 | Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis |
Q36354903 | Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5) |
Q90616747 | NS5 from Dengue Virus Serotype 2 Can Adopt a Conformation Analogous to That of Its Zika Virus and Japanese Encephalitis Virus Homologues |
Q39196605 | Non-Canonical Roles of Dengue Virus Non-Structural Proteins |
Q28548514 | Novel Broad Spectrum Inhibitors Targeting the Flavivirus Methyltransferase |
Q28681742 | Novel cis-acting element within the capsid-coding region enhances flavivirus viral-RNA replication by regulating genome cyclization |
Q58603462 | Persistence and Intra-Host Genetic Evolution of Zika Virus Infection in Symptomatic Adults: A Special View in the Male Reproductive System |
Q47548659 | Positive-sense RNA viruses reveal the complexity and dynamics of the cellular and viral epitranscriptomes during infection. |
Q26247399 | Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling |
Q90029580 | Quantifying the RNA cap epitranscriptome reveals novel caps in cellular and viral RNA |
Q63979733 | RNA Modifications Modulate Activation of Innate Toll-Like Receptors |
Q27468676 | RNAs Containing Modified Nucleotides Fail To Trigger RIG-I Conformational Changes for Innate Immune Signaling |
Q36827340 | Rational design of a flavivirus vaccine by abolishing viral RNA 2'-O methylation |
Q27334248 | Rational design of a live attenuated dengue vaccine: 2'-o-methyltransferase mutants are highly attenuated and immunogenic in mice and macaques |
Q40185164 | Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase |
Q38127643 | Regulation of flavivirus RNA synthesis and capping |
Q36572805 | Reversible RNA adenosine methylation in biological regulation |
Q38174301 | Revisiting dengue virus-host cell interaction: new insights into molecular and cellular virology |
Q35018619 | S-adenosyl-homocysteine is a weakly bound inhibitor for a flaviviral methyltransferase |
Q27028229 | STAT2 signaling and dengue virus infection |
Q38867867 | Structural basis of Zika virus methyltransferase inhibition by sinefungin |
Q38045106 | Structural biology of dengue virus enzymes: towards rational design of therapeutics |
Q35178437 | Structure-based identification of functional residues in the nucleoside-2'-O-methylase domain of Bluetongue virus VP4 capping enzyme. |
Q34070463 | Substitution of NS5 N-terminal domain of dengue virus type 2 RNA with type 4 domain caused impaired replication and emergence of adaptive mutants with enhanced fitness |
Q26970797 | The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing |
Q115250579 | The Dengue Virus Nonstructural Protein 1 (NS1) Interacts with the Putative Epigenetic Regulator DIDO1 to Promote Flavivirus Replication in Mosquito Cells |
Q60031598 | The Multiples Fates of the Flavivirus RNA Genome During Pathogenesis |
Q115204695 | The Nonstructural Proteins 3 and 5 from Flavivirus Modulate Nuclear-Cytoplasmic Transport and Innate Immune Response Targeting Nuclear Proteins |
Q28114691 | The Zika virus methyltransferase: structure and functions for drug design perspectives |
Q115232658 | The dengue virus non-structural protein 1 (NS1) interacts with the putative epigenetic regulator DIDO1 to promote flavivirus replication |
Q34657530 | The flavivirus protease as a target for drug discovery |
Q28539043 | The interface between methyltransferase and polymerase of NS5 is essential for flavivirus replication |
Q40191623 | The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain |
Q42912740 | The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain |
Q59353120 | The methyltransferase domain of the Sudan ebolavirus L protein specifically targets internal adenosines of RNA substrates, in addition to the cap structure |
Q37336931 | The role of sequence context, nucleotide pool balance and stress in 2'-deoxynucleotide misincorporation in viral, bacterial and mammalian RNA. |
Q38218501 | To sense or not to sense viral RNA--essentials of coronavirus innate immune evasion. |
Q34991051 | Two distinct sets of NS2A molecules are responsible for dengue virus RNA synthesis and virion assembly |
Q37666750 | West Nile virus drug discovery |
Q66679244 | Zika Virus Transmission Through Blood Tissue Barriers |
Q35476652 | mRNA maturation in giant viruses: variation on a theme. |
Search more.