Rational incorporation of selenium into temozolomide elicits superior antitumor activity associated with both apoptotic and autophagic cell death

scientific article

Rational incorporation of selenium into temozolomide elicits superior antitumor activity associated with both apoptotic and autophagic cell death is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...735104C
P356DOI10.1371/JOURNAL.PONE.0035104
P3181OpenCitations bibliographic resource ID4905399
P932PMC publication ID3320619
P698PubMed publication ID22496897
P5875ResearchGate publication ID223978158

P2093author name stringLi Zhang
Yi Zhang
Yan Cheng
Jin-Ming Yang
Jason Liao
Shantu Amin
Arun K Sharma
Yuan-Wan Sun
Ugir Hossain Sk
Kathryn J Huber-Keener
Xingcong Ren
P2860cites workInduction of autophagy in temozolomide treated malignant gliomasQ55463470
Selenium compounds inhibit I kappa B kinase (IKK) and nuclear factor-kappa B (NF-kappa B) in prostate cancer cellsQ64378241
Apoptosis induced by DNA damage O6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independentQ73144195
Chemopreventive agents: seleniumQ77425293
Protection against Fatal Sindbis Virus Encephalitis by Beclin, a Novel Bcl-2-Interacting ProteinQ22003920
Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosisQ24338917
Partial Beclin 1 silencing aggravates doxorubicin- and Fas-induced apoptosis in HepG2 cellsQ28241857
Targeting Akt3 signaling in malignant melanoma using isoselenocyanatesQ33408109
Oncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cellsQ33648384
Temozolomide and treatment of malignant glioma.Q33983627
Activation of AMP-activated Protein Kinase by Temozolomide Contributes to Apoptosis in Glioblastoma Cells via p53 Activation and mTORC1 InhibitionQ34412530
Synthesis and evaluation of the anti-inflammatory properties of selenium-derivatives of celecoxib.Q34417632
MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agentsQ34626127
The Akt inhibitor ISC-4 activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.Q35091427
Melanoma chemoprevention in skin reconstructs and mouse xenografts using isoselenocyanate-4.Q35535167
Selenium in cancer prevention: a review of the evidence and mechanism of actionQ36325137
Stress and mTORture signalingQ36623669
Synthesis and anticancer activity comparison of phenylalkyl isoselenocyanates with corresponding naturally occurring and synthetic isothiocyanates.Q37069862
Autophagy: an emerging target for cancer therapy.Q37117376
Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancerQ37707832
Differential sensitivity of various human tumour-derived cell types to apoptosis by organic derivatives of seleniumQ39972955
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cellsQ40600919
SelSA, selenium analogs of SAHA as potent histone deacetylase inhibitorsQ41487113
DNA damage-mediated apoptosis induced by selenium compounds.Q42801439
Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53.Q43188994
Synthesis and antitumor properties of selenocoxib-1 against rat prostate adenocarcinoma cellsQ43240660
Se-methylselenocysteine induces apoptosis through caspase activation in HL-60 cellsQ43564035
Phase II trial of arsenic trioxide and ascorbic acid with temozolomide in patients with metastatic melanoma with or without central nervous system metastasesQ46704707
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectautophagyQ288322
apoptotic processQ14599311
temozolomideQ425088
P304page(s)e35104
P577publication date2012-01-01
P1433published inPLOS OneQ564954
P1476titleRational incorporation of selenium into temozolomide elicits superior antitumor activity associated with both apoptotic and autophagic cell death
P478volume7

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cites work (P2860)
Q34488011Adenovirus-mediated FKHRL1/TM sensitizes melanoma cells to apoptosis induced by temozolomide
Q36769227Cancer chemoprevention research with selenium in the post-SELECT era: Promises and challenges
Q35148935Cytotoxic activity of the methanolic extract of Turnera diffusa Willd on breast cancer cells
Q34517339Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas
Q27015669Friend or foe? The current epidemiologic evidence on selenium and human cancer risk
Q38692702Glutathione in metastases: From mechanisms to clinical applications
Q40231870HIF-1α Inhibition Sensitized Pituitary Adenoma Cells to Temozolomide by Regulating Presenilin 1 Expression and Autophagy
Q38932012Human Lung Cancer Cell Line A-549 ATCC Is Differentially Affected by Supranutritional Organic and Inorganic Selenium.
Q37301756Magnolol and honokiol exert a synergistic anti-tumor effect through autophagy and apoptosis in human glioblastomas
Q38077547Post SELECT: Selenium on Trial
Q35658137Redox-active selenium compounds--from toxicity and cell death to cancer treatment
Q30357185Regulation of p53wt glioma cell proliferation by androgen receptor-mediated inhibition of small VCP/p97-interacting protein expression.
Q38040788Selenium Compounds, Apoptosis and Other Types of Cell Death: An Overview for Cancer Therapy
Q38243994Selenium action in neuro-oncology
Q28087476The Role of Glucose Modulation and Dietary Supplementation in Patients With Central Nervous System Tumors
Q37236107Therapeutic Targeting of Autophagy in Disease: Biology and Pharmacology
Q57469839Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cells in vitro via Akt-mediated pathway
Q57180130Tunable Stability of Imidazotetrazines Leads to a Potent Compound for Glioblastoma

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