Biochemical characterization of WbpA, a UDP-N-acetyl-D-glucosamine 6-dehydrogenase involved in O-antigen biosynthesis in Pseudomonas aeruginosa PAO1

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Biochemical characterization of WbpA, a UDP-N-acetyl-D-glucosamine 6-dehydrogenase involved in O-antigen biosynthesis in Pseudomonas aeruginosa PAO1 is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M404749200
P698PubMed publication ID15226302
P5875ResearchGate publication ID8482768

P2093author name stringJoseph S. Lam
Craig Daniels
Jean-Robert Brisson
Suzon Larocque
Cory Q. Wenzel
Wayne L. Miller
P2860cites workActivation of the herpes simplex virus type 1 proteaseQ45788855
UDP-galactofuranose precursor required for formation of the lipopolysaccharide O antigen of Klebsiella pneumoniae serotype O1 is synthesized by the product of the rfbDKPO1 geneQ48053898
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Covalent Adduct Formation with a Mutated Enzyme: Evidence for a Thioester Intermediate in the Reaction Catalyzed by UDP-Glucose DehydrogenaseQ57904070
Properties and Kinetic Analysis of UDP-glucose Dehydrogenase from Group A StreptococciQ57904072
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Crystal Structure of GDP-Mannose Dehydrogenase: A Key Enzyme of Alginate Biosynthesis in P. aeruginosa,Q27641022
Novel active site in Escherichia coli fructose 1,6-bisphosphate aldolaseQ27733462
The Hofmeister effect and the behaviour of water at interfacesQ28306938
Molecular characterization of the Pseudomonas aeruginosa serotype O5 (PAO1) B-band lipopolysaccharide gene clusterQ28492492
Topological and functional characterization of WbpM, an inner membrane UDP-GlcNAc C6 dehydratase essential for lipopolysaccharide biosynthesis in Pseudomonas aeruginosaQ28493228
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Pseudomonas aeruginosa lipopolysaccharides and pathogenesisQ30469943
Staphylococcus aureus Cap5O has UDP-ManNAc dehydrogenase activity and is essential for capsule expressionQ34005978
Allosterism and cooperativity in Pseudomonas aeruginosa GDP-mannose dehydrogenaseQ34140611
UDPacetylglucosamine dehydrogenase from Achromobacter georgiopolitanumQ34206351
Visualization of Pseudomonas aeruginosa O antigens by using a protein A-dextran-colloidal gold conjugate with both immunoglobulin G and immunoglobulin M monoclonal antibodiesQ36240668
The serum sensitivity, colonial morphology, serogroup specificity, and outer membrane protein of Pseudomonas aeruginosa strains isolated from several clinical sitesQ38480623
Biosynthesis of 2-acetamido-2,6-dideoxy-L-hexoses in bacteria follows a pattern distinct from those of the pathways of 6-deoxy-L-hexosesQ41860064
A study of the subunit structure and the thiol reactivity of bovine liver uridine diphosphate glucose dehydrogenaseQ42919111
Three highly conserved proteins catalyze the conversion of UDP-N-acetyl-D-glucosamine to precursors for the biosynthesis of O antigen in Pseudomonas aeruginosa O11 and capsule in Staphylococcus aureus type 5. Implications for the UDP-N-acetyl-L-fucoQ44237678
P433issue36
P407language of work or nameEnglishQ1860
P921main subjectPseudomonas aeruginosaQ31856
glucosamineQ32907954
P304page(s)37551–37558
P577publication date2004-09-03
P1433published inJournal of Biological ChemistryQ867727
P1476titleBiochemical characterization of WbpA, a UDP-N-acetyl-D-glucosamine 6-dehydrogenase involved in O-antigen biosynthesis in Pseudomonas aeruginosa PAO1
P478volume279

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cites work (P2860)
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Q24648470Biosynthesis of UDP-GlcNAc(3NAc)A by WbpB, WbpE, and WbpD: enzymes in the Wbp pathway responsible for O-antigen assembly in Pseudomonas aeruginosa PAO1
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Q34023007Flagellin glycosylation in Pseudomonas aeruginosa PAK requires the O-antigen biosynthesis enzyme WbpO
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Q36835447Vi antigen biosynthesis in Salmonella typhi: characterization of UDP-N-acetylglucosamine C-6 dehydrogenase (TviB) and UDP-N-acetylglucosaminuronic acid C-4 epimerase (TviC)

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