Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex

scientific journal article

Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2011PNAS..10811381S
P356DOI10.1073/PNAS.1019711108
P3181OpenCitations bibliographic resource ID983076
P932PMC publication ID3136327
P698PubMed publication ID21709260
P5875ResearchGate publication ID51253731

P50authorAnjana RaoQ85941651
P2093author name stringSonia Sharma
Zhigang Li
David B. Sacks
Patrick G. Hogan
Beate Baust
Shalini Oberdoerffer
Gregory M. Findlay
Hozefa S. Bandukwala
Valentina Schmidt
P2860cites workThe genetic signatures of noncoding RNAsQ21092463
A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complexQ22009369
Long noncoding RNA as modular scaffold of histone modification complexesQ22065890
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFATQ24306261
IQGAP proteins are integral components of cytoskeletal regulationQ24535739
The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivatorQ24548002
Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1Q24554337
Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and toleranceQ24642248
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expressionQ24654249
IQGAPs in cancer: a family of scaffold proteins underlying tumorigenesisQ24655426
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAsQ24673619
NFAT Binding and Regulation of T Cell Activation by the Cytoplasmic Scaffolding Homer ProteinsQ27649708
RNA-mediated response to heat shock in mammalian cellsQ28118457
Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activityQ28140993
A strategy for probing the function of noncoding RNAs finds a repressor of NFATQ28270512
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel functionQ28305026
The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatinQ28506981
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 responseQ28592069
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosomeQ29547359
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expressionQ29614326
Evolution and functions of long noncoding RNAsQ29614331
Long noncoding RNAs: functional surprises from the RNA worldQ29615826
Transcriptional regulation by calcium, calcineurin, and NFATQ29620410
Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cellsQ34003618
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.Q34504363
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cellsQ34581070
Eukaryotic regulatory RNAs: an answer to the 'genome complexity' conundrumQ34599474
Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLsQ37061865
Scaffold proteins and immune-cell signallingQ37357014
Biochemical and functional characterization of Orai proteinsQ40172328
A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1.Q40815624
IQGAP1 promotes cell motility and invasionQ42798469
Centrosome polarization delivers secretory granules to the immunological synapse.Q53587934
IQGAP1 integrates Ca2+/calmodulin and Cdc42 signalingQ77732943
P2507corrigendum / erratumCorrection for Sharma et al., Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complexQ93539434
P433issue28
P407language of work or nameEnglishQ1860
P921main subjectCasein kinase 1, epsilonQ15326636
Interferon gammaQ21494550
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2Q21981052
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1aQ21981053
Glycogen synthase kinase 3 betaQ21983050
IQ motif containing GTPase activating protein 1Q21985377
Nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2Q21987765
P304page(s)11381–11386
P577publication date2011-07-12
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleDephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex
P478volume108

Reverse relations

cites work (P2860)
Q90615917A PI3K/AKT Scaffolding Protein, IQ Motif-Containing GTPase Associating Protein 1 (IQGAP1), Promotes Head and Neck Carcinogenesis
Q24322334A cytoplasmic NF-κB interacting long noncoding RNA blocks IκB phosphorylation and suppresses breast cancer metastasis
Q37464844A feed-forward loop between lncARSR and YAP activity promotes expansion of renal tumour-initiating cells
Q89013363An increase in LRRK2 suppresses autophagy and enhances Dectin-1-induced immunity in a mouse model of colitis
Q41968043An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry
Q90352972Angio-LncRs: LncRNAs that regulate angiogenesis and vascular disease
Q40721443BcIqg1, a fungal IQGAP homolog, interacts with NADPH oxidase, MAP kinase and calcium signaling proteins and regulates virulence and development in Botrytis cinerea
Q55041006Besides Pathology: Long Non-Coding RNA in Cell and Tissue Homeostasis.
Q52559580Beyond mRNA: The role of non-coding RNAs in normal and aberrant hematopoiesis.
Q39027949Biogenesis and Transcriptional Regulation of Long Noncoding RNAs in the Human Immune System.
Q38848213Biological Response Modifier in Cancer Immunotherapy
Q38186014Calcineurin-NFAT activation and DSCR-1 auto-inhibitory loop: how is homoeostasis regulated?
Q33744631Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs
Q38737055Characters, functions and clinical perspectives of long non-coding RNAs
Q40291390Circulating long non-coding RNAs NRON and MHRT as novel predictive biomarkers of heart failure
Q35793475Conserved Motifs within Hepatitis C Virus Envelope (E2) RNA and Protein Independently Inhibit T Cell Activation
Q34789303Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate
Q50053910Control of Immune Cell Homeostasis and Function by lncRNAs.
Q38770693Critical Link Between Epigenetics and Transcription Factors in the Induction of Autoimmunity: a Comprehensive Review
Q56747218Deep sequencing of the mouse lung transcriptome reveals distinct long non-coding RNAs expression associated with the high virulence of H5N1 avian influenza virus in mice
Q37595381Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models
Q36368164Distinct activation properties of the nuclear factor of activated T-cells (NFAT) isoforms NFATc3 and NFATc4 in neurons.
Q91771278Diverging RNPs: Toward Understanding lncRNA-Protein Interactions and Functions
Q38975300Dnmt3a restrains mast cell inflammatory responses
Q62658486Don't move: LRRK2 arrests NFAT in the cytoplasm
Q38987117Dynamic assembly of a membrane signaling complex enables selective activation of NFAT by Orai1.
Q47657395Emerging mechanisms of long noncoding RNA function during normal and malignant hematopoiesis
Q35104397Epigenetic regulation of lncRNA connects ubiquitin-proteasome system with infection-inflammation in preterm births and preterm premature rupture of membranes
Q37204039Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter
Q35381106Exploring the secrets of long noncoding RNAs
Q35540538Expression and functions of long noncoding RNAs during human T helper cell differentiation.
Q37237471Functional diversity of long non-coding RNAs in immune regulation
Q38638798Gene regulation in the immune system by long noncoding RNAs.
Q36190172Global analysis of biogenesis, stability and sub-cellular localization of lncRNAs mapping to intragenic regions of the human genome
Q34356521Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes
Q55462178IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells.
Q39579018IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity
Q35713259IQGAP1 and its binding proteins control diverse biological functions
Q37691687IQGAP1 binds to estrogen receptor-α and modulates its function
Q37985802IQGAP1: a regulator of intracellular spacetime relativity
Q38367073IQGAP1: insights into the function of a molecular puppeteer
Q35132297IQGAPs choreograph cellular signaling from the membrane to the nucleus
Q37594217IRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling
Q38627387Identification and characterization of a long non-coding RNA up-regulated during HIV-1 infection.
Q39104939Immunobiology of Long Noncoding RNAs.
Q47569148Immunological Disorders: Regulation of Ca2+ Signaling in T Lymphocytes
Q40384231Inhibition of lncRNA MIR31HG Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells
Q33945848Integrative genomic and transcriptomic analysis identified candidate genes implicated in the pathogenesis of hepatosplenic T-cell lymphoma
Q59794483Interactome determination of a Long Noncoding RNA implicated in Embryonic Stem Cell Self-Renewal
Q36134420KPNB1 mediates PER/CRY nuclear translocation and circadian clock function
Q39206438LRRK2 and the Immune System
Q94569516LncRNA Nron regulates osteoclastogenesis during orthodontic bone resorption
Q39009966LncRNA as a Therapeutic Target for Angiogenesis
Q33608858LncRNAs and immunity: watchdogs for host pathogen interactions.
Q92129207Long Non-Coding RNA Function in CD4+ T Cells: What We Know and What Next?
Q47111389Long Non-Coding RNAs: Emerging and Versatile Regulators in Host-Virus Interactions.
Q92921576Long Noncoding RNA in Myeloid and Lymphoid Cell Differentiation, Polarization and Function
Q38868308Long Noncoding RNA: Recent Updates in Atherosclerosis
Q33568760Long non-coding RNA NKILA inhibits migration and invasion of non-small cell lung cancer via NF-κB/Snail pathway
Q34616243Long non-coding RNAs and control of gene expression in the immune system
Q36446804Long non-coding RNAs in innate and adaptive immunity
Q28070169Long non-coding RNAs in normal and malignant hematopoiesis
Q38239035Long non-coding RNAs in the regulation of the immune response
Q40405868Long noncoding RNA HULC modulates the phosphorylation of YB-1 through serving as a scaffold of extracellular signal-regulated kinase and YB-1 to enhance hepatocarcinogenesis
Q38769321Long noncoding RNAs as regulators of Toll-like receptor signaling and innate immunity
Q38625682Long noncoding RNAs in T lymphocytes
Q26798082Long noncoding RNAs in innate immunity
Q36553653Long noncoding RNAs in viral infections
Q90261882Long noncoding RNAs: Novel regulators of virus-host interactions
Q38380213Long noncoding RNAs: a potent source of regulation in immunity and disease
Q26991873Long noncoding RNAs: past, present, and future
Q55169246Micro-RNA Feedback Loops Modulating the Calcineurin/NFAT Signaling Pathway.
Q46307966MicroRNA in Immune Regulation.
Q38040813NFAT gene family in inflammation and cancer
Q39591211NFATc1/αA: The other Face of NFAT Factors in Lymphocytes
Q96576417NORAD orchestrates endometrial cancer progression by sequestering FUBP1 nuclear localization to promote cell apoptosis
Q92062346Non-Coding RNAs in CD4+ T Cells: New Insights Into the Pathogenesis of Systemic Lupus Erythematosus
Q89836573Non-coding RNAs in CD8 T cell biology
Q26991500Non-coding RNAs in muscle dystrophies
Q38212814Noncoding RNA and its associated proteins as regulatory elements of the immune system.
Q26823718Noncoding RNA in oncogenesis: a new era of identifying key players
Q38885490Noncoding RNAs in Cancer Immunology.
Q37462378Orai1-NFAT signalling pathway triggered by T cell receptor stimulation
Q89818787Pan-cancer characterization of immune-related lncRNAs identifies potential oncogenic biomarkers
Q64105160Potential Implications of Long Noncoding RNAs in Autoimmune Diseases
Q38130412Potential pathological and functional links between long noncoding RNAs and hematopoiesis
Q39292842Protein sequestration as a normal function of long noncoding RNAs and a pathogenic mechanism of RNAs containing nucleotide repeat expansions
Q38189284Regulatory non-coding RNAs: revolutionizing the RNA world
Q36789282Research resource: identification of novel coregulators specific for thyroid hormone receptor-β2.
Q38572497Role of Ets Proteins in Development, Differentiation, and Function of T-Cell Subsets
Q38136969Role of long non-coding RNAs in normal and malignant hematopoiesis
Q39365927Roles of LncRNAs in Viral Infections
Q39031292S100A1 and S100B: Calcium Sensors at the Cross-Roads of Multiple Chondrogenic Pathways
Q46706123Short-term memory of danger signals and environmental stimuli in immune cells
Q28118440TMEM110 regulates the maintenance and remodeling of mammalian ER-plasma membrane junctions competent for STIM-ORAI signaling
Q64946532Targeting Protein Kinases to Enhance the Response to anti-PD-1/PD-L1 Immunotherapy.
Q38775132The AS-RBM15 lncRNA enhances RBM15 protein translation during megakaryocyte differentiation
Q36346331The Long Noncoding RNA IFNG-AS1 Promotes T Helper Type 1 Cells Response in Patients with Hashimoto's Thyroiditis
Q92647937The NRON complex controls circadian clock function through regulated PER and CRY nuclear translocation
Q93037103The Osteogenic Niche Is a Calcium Reservoir of Bone Micrometastases and Confers Unexpected Therapeutic Vulnerability
Q36932916The Runt domain of AML1 (RUNX1) binds a sequence-conserved RNA motif that mimics a DNA element
Q38885465The Working Modules of Long Noncoding RNAs in Cancer Cells
Q27023065The biology of IQGAP proteins: beyond the cytoskeleton
Q42126397The cytoskeletal adaptor protein IQGAP1 regulates TCR-mediated signaling and filamentous actin dynamics.
Q35134014The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins.
Q36079983The role of LRRK2 in inflammatory bowel disease
Q97072562The role of Long Non-Coding RNAs (lncRNAs) and downstream signaling pathways in Leukemia progression
Q49596604The role of long non-coding RNAs in rheumatic diseases.
Q34245251Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity.
Q34631682Transcriptional and epigenetic regulation of T-helper lineage specification
Q58762555Z Probe, An Efficient Tool for Characterizing Long Non-Coding RNA in FFPE Tissues
Q52343644lncRNA-NKILA/NF-κB feedback loop modulates laryngeal cancer cell proliferation, invasion, and radioresistance.
Q26775906lncRNAs regulate the innate immune response to viral infection
Q41390605miR-9 enhances the transactivation of nuclear factor of activated T cells by targeting KPNB1 and DYRK1B.
Q28082698ncRNA-regulated immune response and its role in inflammatory lung diseases

Search more.