Lack of hypoxia-inducible factor-1 alpha impairs midbrain neural precursor cells involving vascular endothelial growth factor signaling

scientific journal article

Lack of hypoxia-inducible factor-1 alpha impairs midbrain neural precursor cells involving vascular endothelial growth factor signaling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.2482-06.2007
P932PMC publication ID6672078
P698PubMed publication ID17215402

P2093author name stringAlexander Storch
Manfred Gerlach
Florian Wegner
Johannes Schwarz
Roland H Wenger
Javorina Milosevic
Martina Maisel
Julia Leuchtenberger
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The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes.Q48421828
Low atmospheric oxygen avoids maturation, senescence and cell death of murine mesencephalic neural precursorsQ49088945
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Primitive human HPCs are better maintained and expanded in vitro at 1 percent oxygen than at 20 percentQ73337460
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Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1Q28282227
Defective brain development in mice lacking the Hif-1alpha gene in neural cellsQ28512300
Regulation of tyrosine hydroxylase promoter activity by the von Hippel-Lindau tumor suppressor protein and hypoxia-inducible transcription factorsQ28578496
HIF-1 alpha is required for solid tumor formation and embryonic vascularization.Q28588778
Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disordersQ29614754
For the long run: maintaining germinal niches in the adult brainQ29615156
Conditional gene knockout using cre recombinaseQ33935863
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Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury.Q34075461
HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.Q34471121
Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expressionQ34770083
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In vivo evidence that erythropoietin protects neurons from ischemic damageQ36477827
VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemiaQ39774417
Hypoxia requires notch signaling to maintain the undifferentiated cell stateQ40356897
Neurorescue effects of VEGF on a rat model of Parkinson's diseaseQ40393076
The homeodomain transcription factor Pitx3 facilitates differentiation of mouse embryonic stem cells into AHD2-expressing dopaminergic neurons.Q40462051
Long-term proliferation and dopaminergic differentiation of human mesencephalic neural precursor cellsQ40789736
Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth.Q40861131
A post mortem study on neurochemical markers of dopaminergic, GABA-ergic and glutamatergic neurons in basal ganglia-thalamocortical circuits in Parkinson syndromeQ42528847
Vascular endothelial growth factor rescues hippocampal neurons from glutamate-induced toxicity: signal transduction cascades.Q43601730
Ventral tegmental area dopamine neurons are resistant to human mutant alpha-synuclein overexpression.Q44086156
The regulation of glucose metabolism by HIF-1 mediates a neuroprotective response to amyloid beta peptideQ44505340
The DNA damage-induced decrease of Bcl-2 is secondary to the activation of apoptotic effector caspasesQ44611170
Knockin mice with Leu9'Ser alpha4-nicotinic receptors: substantia nigra dopaminergic neurons are hypersensitive to agonist and lost postnatally.Q44938226
Culture in reduced levels of oxygen promotes clonogenic sympathoadrenal differentiation by isolated neural crest stem cells.Q46020210
Protecting neuronsQ46154638
Hypoxia-induced long-term increase of dopamine and tyrosine hydroxylase mRNA levels.Q46396547
Erythropoietin protects dopaminergic neurons and improves neurobehavioral outcomes in juvenile rats after neonatal hypoxia-ischemiaQ46628252
K-ATP channels promote the differential degeneration of dopaminergic midbrain neuronsQ46813537
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectbrainQ1073
hypoxiaQ105688
endotheliumQ111140
Hypoxia inducible factor 1, alpha subunitQ21981069
Vascular endothelial growth factor AQ21992409
P304page(s)412-421
P577publication date2007-01-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleLack of hypoxia-inducible factor-1 alpha impairs midbrain neural precursor cells involving vascular endothelial growth factor signaling
P478volume27

Reverse relations

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