Oxygen in health and disease: regulation of oxygen homeostasis--clinical implications

scientific article published on March 2009

Oxygen in health and disease: regulation of oxygen homeostasis--clinical implications is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1017888042
P356DOI10.1203/PDR.0B013E31818FC83F
P698PubMed publication ID18852690
P5875ResearchGate publication ID23317774

P50authorOla Didrik SaugstadQ47546644
P2093author name stringEmin Maltepe
P2860cites workArchean Molecular Fossils and the Early Rise of EukaryotesQ22065553
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensingQ24291102
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylationQ24291783
A conserved family of prolyl-4-hydroxylases that modify HIFQ24291794
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tensionQ24307473
The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic developmentQ24595910
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylationQ27860876
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alphaQ28259513
HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxiaQ28300406
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumptionQ28300415
Lack of hypoxia-inducible factor-1 alpha impairs midbrain neural precursor cells involving vascular endothelial growth factor signalingQ28506157
Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2Q28508549
Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature miceQ28508637
Defective brain development in mice lacking the Hif-1alpha gene in neural cellsQ28512300
HIF-1 alpha is required for solid tumor formation and embryonic vascularization.Q28588778
VEGFA is necessary for chondrocyte survival during bone developmentQ28590528
Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- miceQ28594703
Purification and characterization of hypoxia-inducible factor 1Q28678375
Mitochondrial reactive oxygen species trigger hypoxia-induced transcriptionQ29614203
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensingQ29615506
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumoursQ29618396
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblastsQ29618748
Avoiding hyperoxia in infants 1250 g is associated with improved short- and long-term outcomesQ30463931
Pulse oximetry, severe retinopathy, and outcome at one year in babies of less than 28 weeks gestationQ30473664
Can Changes in Clinical Practice Decrease the Incidence of Severe Retinopathy of Prematurity in Very Low Birth Weight Infants?Q30477134
Effects of oxygen toxicity on early development of mouse embryosQ33432686
Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development.Q47645076
HO-2 provides endogenous protection against oxidative stress and apoptosis caused by TNF-alpha in cerebral vascular endothelial cellsQ48478299
The developmental potential of the human oocyte is related to the dissolved oxygen content of follicular fluid: association with vascular endothelial growth factor levels and perifollicular blood flow characteristicsQ48958485
Factors affecting the developmental competence of mouse oocytes grown in vitro: oxygen concentrationQ49030684
Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.Q52195684
Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes.Q52563106
Plasma Hypoxanthine Concentrations in PigsQ58144098
Hypoxanthine as a Measurement of HypoxiaQ58144110
Maternal arterial connections to the placental intervillous space during the first trimester of human pregnancy: the Boyd collection revisitedQ33732595
Toxic effects of oxygen on human embryo developmentQ34066138
HIF-1 and mechanisms of hypoxia sensingQ34180645
Oxygen poisoning and x-irradiation: a mechanism in commonQ34235248
Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agentQ34501431
Carbon monoxide-induced suspended animation protects against hypoxic damage in Caenorhabditis elegansQ34836826
Oxygen deprivation induced cell death: an updateQ34949087
Genetic models in applied physiology: invited review: effect of oxygen deprivation on cell cycle activity: a profile of delay and arrestQ35101172
Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activationQ35120687
Multilineage embryonic hematopoiesis requires hypoxic ARNT activityQ35207418
Placental cell fates are regulated in vivo by HIF-mediated hypoxia responsesQ35209175
Mitochondrial regulation of oxygen sensingQ36250880
Oxygen deprivation causes suspended animation in the zebrafish embryoQ36304805
Inhibition of NGF deprivation-induced death by low oxygen involves suppression of BIMEL and activation of HIF-1Q36321474
Free radicals, mitochondria, and hypoxia-ischemia in the developing brainQ36380301
Defective placental vasculogenesis causes embryonic lethality in VHL-deficient miceQ36551258
Culture of rabbit zygotes into blastocysts in protein-free medium with one to twenty per cent oxygenQ36766323
Executive summary of the workshop on oxygen in neonatal therapies: controversies and opportunities for researchQ36778370
Optimal oxygenation at birth and in the neonatal periodQ36851888
Oxygen, the lead actor in the pathophysiologic drama: enactment of the trinity of normoxia, hypoxia, and hyperoxia in disease and therapyQ36932714
Oxygen-reactive species and antioxidant responses during development: the metabolic paradox of cellular differentiationQ37630871
Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical productionQ39634654
Oxygen radicals and pulmonary damageQ39832951
A targeted antioxidant reveals the importance of mitochondrial reactive oxygen species in the hypoxic signaling of HIF-1alpha.Q40429133
ERK activation upon hypoxia: involvement in HIF-1 activationQ40898952
Maternal circulation in the first-trimester human placenta--myth or reality?Q41392140
Expression of NADPH oxidases and enhanced H(2)O(2)-generating activity in human coronary artery endothelial cells upon induction with tumor necrosis factor-alphaQ42439900
Suspended Animation in C. elegans Requires the Spindle CheckpointQ42612760
ARNT-deficient mice and placental differentiationQ43703428
Intrauterine Oxygen Tension in the Rat During Progestation: Its Possible Relation to Carbohydrate Metabolism and the Regulation of NidationQ43978222
Hyperoxia-induced NAD(P)H oxidase activation and regulation by MAP kinases in human lung endothelial cellsQ44185726
HIF-1alpha controls extracellular matrix synthesis by epiphyseal chondrocytesQ44383061
Tolerance to low O2: lessons from invertebrate genetic modelsQ44825477
Life with oxygenQ45345070
Reactive oxygen metabolites relax the lamb ductus arteriosus by stimulating prostaglandin production.Q46040152
Hypoxia-inducible factor-dependent histone deacetylase activity determines stem cell fate in the placentaQ46081787
To oxygenate or not to oxygenate--that is the questionQ46425704
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylationQ46626427
Regulation of human placental development by oxygen tensionQ46733260
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectoxygenQ629
P304page(s)261-268
P577publication date2009-03-01
P1433published inPediatric ResearchQ7159215
P1476titleOxygen in health and disease: regulation of oxygen homeostasis--clinical implications
P478volume65

Reverse relations

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