Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

scientific article (publication date: June 2005)

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CMET.2005.05.001
P3181OpenCitations bibliographic resource ID1353935
P698PubMed publication ID16054089
P5875ResearchGate publication ID7691917

P2093author name stringChen H
Liu L
Schumacker PT
Hammerling U
Simon MC
Robin E
Guzy RD
Hoyos B
Mansfield KD
P2860cites workThe tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysisQ22009936
Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementationQ29614475
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
oxygen sensingQ69984017
hypoxiaQ105688
P304page(s)401-8
P577publication date2005-06-01
P1433published inCell MetabolismQ1254684
P1476titleMitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
P478volume1

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Q37542215Mitochondrial regulation of cell survival and death during low-oxygen conditions
Q50137432Mitochondrial regulation of hematopoietic stem cells
Q37777273Mitochondrial reprogramming through cardiac oxygen sensors in ischaemic heart disease
Q42128038Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury
Q92547045Mitochondrial transport serves as a mitochondrial quality control strategy in axons: Implications for central nervous system disorders
Q37369860Mitochondrial-associated metabolic disorders: foundations, pathologies and recent progress
Q43478776Mitonuclear Interactions Mediate Transcriptional Responses to Hypoxia in Drosophila
Q36078557Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis
Q30580906Modeling the transcriptional regulatory network that controls the early hypoxic response in Candida albicans
Q64899482Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications.
Q28081657Molecular Connections between Cancer Cell Metabolism and the Tumor Microenvironment
Q92192354Molecular and Cellular Response of Co-cultured Cells toward Cobalt Chloride (CoCl2)-Induced Hypoxia
Q28297656Molecular mechanisms of action and therapeutic uses of pharmacological inhibitors of HIF-prolyl 4-hydroxylases for treatment of ischemic diseases
Q28080772Molecular mechanisms of ischemic preconditioning in the kidney
Q33945544Molecular-targeted antitumor agents. 19. Furospongolide from a marine Lendenfeldia sp. sponge inhibits hypoxia-inducible factor-1 activation in breast tumor cells
Q35641801Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro
Q28483921Multistationary and oscillatory modes of free radicals generation by the mitochondrial respiratory chain revealed by a bifurcation analysis
Q90404445N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA
Q91330018NER-factor DDB2 regulates HIF1α and hypoxia-response genes in HNSCC
Q35486167NNC 55-0396, a T-type Ca2+ channel inhibitor, inhibits angiogenesis via suppression of hypoxia-inducible factor-1α signal transduction
Q35408681NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activation
Q37154447NOX2 Antisense Attenuates Hypoxia-Induced Oxidative Stress and Apoptosis in Cardiomyocyte
Q98164577Na+ controls hypoxic signalling by the mitochondrial respiratory chain
Q24620427Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
Q89302561Neonatal Intermittent Hypoxia, Reactive Oxygen Species, and Oxygen-Induced Retinopathy
Q37221793Neonatal intermittent hypoxia leads to long-lasting facilitation of acute hypoxia-evoked catecholamine secretion from rat chromaffin cells
Q48830221Neurodegeneration of Drosophila drop-dead mutants is associated with hypoxia in the brain
Q26865964Neuroglobin, a novel target for endogenous neuroprotection against stroke and neurodegenerative disorders
Q36560145Neuroprotection by Polynitrogen Manganese Complexes: Regulation of Reactive Oxygen Species-Related Pathways
Q37418263Neuroprotective roles and mechanisms of neuroglobin
Q37598306New insights into molecular mechanisms of diabetic kidney disease
Q40009227New method for the detection of reactive oxygen species in anti-tumoural activity of adriamycin: a comparison between hypoxic and normoxic cells
Q35926937Nitric oxide produced by cytochrome c oxidase helps stabilize HIF-1α in hypoxic mammalian cells
Q89905540Nix-Mediated Mitophagy Modulates Mitochondrial Damage During Intestinal Inflammation
Q38351687Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases.
Q36736166Non-heme dioxygenases: cellular sensors and regulators jelly rolled into one?
Q38550320Notch signaling and M1 macrophage activation in obesity-alcohol synergism
Q39143886Nrf2 activation supports cell survival during hypoxia and hypoxia/reoxygenation in cardiomyoblasts; the roles of reactive oxygen and nitrogen species
Q28828596Nrf2 is the key to chemotherapy resistance in MCF7 breast cancer cells under hypoxia
Q92480118O-GlcNAcylation of PGK1 coordinates glycolysis and TCA cycle to promote tumor growth
Q36569981O2 sensing, mitochondria and ROS signaling: The fog is lifting
Q28084261Obstructive sleep apnea, pain, and opioids: is the riddle solved?
Q37522854Occult cardiotoxicity--toxic effects on cardiac ischemic tolerance
Q38004740Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia
Q34072314Overcoming hypoxic-resistance of tumor cells to TRAIL-induced apoptosis through melatonin
Q28384392Oxidant Mechanisms in Renal Injury and Disease
Q50684490Oxidant stress during simulated ischemia primes cardiomyocytes for cell death during reperfusion.
Q37579737Oxidative mechanisms of brain dysfunction during sepsis
Q43079012Oxidative protein modification alters proteostasis under acute hypobaric hypoxia in skeletal muscles: a comprehensive in vivo study
Q27011273Oxidative stress and antioxidant activity in hypothermia and rewarming: can RONS modulate the beneficial effects of therapeutic hypothermia?
Q37501271Oxidative stress and cardiovascular disease: novel tools give (free) radical insight
Q41843353Oxidative stress and hypoxia-induced factor 1α expression in gastric ischemia
Q37245117Oxidative stress in the regulation of normal and neoplastic hematopoiesis
Q39077869Oxidative stress induced mitochondrial protein kinase A mediates cytochrome c oxidase dysfunction
Q40683231Oxidative stress mediates the pathogenic effect of different Alzheimer's disease risk factors
Q42178112Oxidative stress, tumor microenvironment, and metabolic reprogramming: a diabolic liaison
Q57053390Oxygen Regulation in Development: Lessons from Embryogenesis towards Tissue Engineering
Q34876618Oxygen Sensing, Cardiac Ischemia, HIF-1α and Some Emerging Concepts
Q38961810Oxygen availability and metabolic adaptations
Q47903998Oxygen availability and metabolic reprogramming in cancer
Q35287980Oxygen gradients for open well cellular cultures via microfluidic substrates
Q37293099Oxygen in health and disease: regulation of oxygen homeostasis--clinical implications
Q29617805Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway
Q36542391Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia.
Q36997538Oxygen sensing in hypoxic pulmonary vasoconstriction: using new tools to answer an age-old question
Q36710281Oxygen sensing: recent insights from idiopathic erythrocytosis
Q28576990Oxygen tension regulates mitochondrial DNA-encoded complex I gene expression
Q36326686Oxygen versus Reactive Oxygen in the Regulation of HIF-1α: The Balance Tips
Q36804611Oxygen, epigenetics and stem cell fate
Q36842794Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1.
Q51685509Oxygen-induced plasticity in tracheal morphology and discontinuous gas exchange cycles in cockroaches Nauphoeta cinerea.
Q27939786Oxygen-regulated isoforms of cytochrome c oxidase have differential effects on its nitric oxide production and on hypoxic signaling
Q33883415PEDF and PEDF-derived peptide 44mer protect cardiomyocytes against hypoxia-induced apoptosis and necroptosis via anti-oxidative effect
Q33977034PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage
Q37076957PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells
Q38769889PIM Kinase Inhibitors Kill Hypoxic Tumor Cells by Reducing Nrf2 Signaling and Increasing Reactive Oxygen Species
Q100737209PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia
Q64271139Palmitic acid-induced autophagy increases reactive oxygen species via the Ca/PKCα/NOX4 pathway and impairs endothelial function in human umbilical vein endothelial cells
Q36957828Paradoxical effect of mitochondrial respiratory chain impairment on insulin signaling and glucose transport in adipose cells
Q33296881Pathway switching explains the sharp response characteristic of hypoxia response network
Q38323862Perinuclear mitochondrial clustering creates an oxidant-rich nuclear domain required for hypoxia-induced transcription
Q35654714Peroxiredoxin-5 targeted to the mitochondrial intermembrane space attenuates hypoxia-induced reactive oxygen species signalling
Q61808369Peroxiredoxins in Cancer and Response to Radiation Therapies
Q42512019Pharmacological stimulation of nuclear factor (erythroid-derived 2)-like 2 translation activates antioxidant responses.
Q64991870Phosphorylation of human TRM9L integrates multiple stress-signaling pathways for tumor growth suppression.
Q42730944Phylogenetic ubiquity of the effects of altered ubiquinone biosynthesis on survival
Q36523591Physiological roles for amyloid beta peptides
Q29620297Physiological roles of mitochondrial reactive oxygen species
Q41213635Pluripotent Stem Cell Metabolism and Mitochondria: Beyond ATP.
Q35613008Post-treatment with the combination of 5-aminoimidazole-4-carboxyamide ribonucleoside and carnitine improves renal function after ischemia/reperfusion injury
Q51000349Postpneumonectomy lung expansion elicits hypoxia-inducible factor-1alpha signaling.
Q42661742Primary role of mitochondrial Rieske iron-sulfur protein in hypoxic ROS production in pulmonary artery myocytes.
Q90061141Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress
Q38989140Prolyl hydroxylase domain enzymes: important regulators of cancer metabolism
Q37657590Prolyl-hydroxylase 3: Evolving Roles for an Ancient Signaling Protein
Q36072645Promotion of Survival and Engraftment of Transplanted Adipose Tissue-Derived Stromal and Vascular Cells by Overexpression of Manganese Superoxide Dismutase
Q92578363Protective effect of nobiletin on isolated human islets survival and function against hypoxia and oxidative stress-induced apoptosis
Q34030929Protein modulation in mouse heart under acute and chronic hypoxia.
Q38151765Proteomics and metabolomics in cancer drug development
Q46551981Psoriasin (S100A7) promotes stress-induced angiogenesis
Q36026989RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect
Q38012102ROS and SOCE: recent advances and controversies in the regulation of STIM and Orai.
Q39253194ROS in Cancer: The Burning Question
Q36941952Radiation Promptly Alters Cancer Live Cell Metabolic Fluxes: An In Vitro Demonstration.
Q45834311Reactive Oxygen Species and NOX Enzymes Are Emerging as Key Players in Cutaneous Wound Repair
Q38996471Reactive Oxygen Species and Oxidative Stress in Obesity-Recent Findings and Empirical Approaches
Q89373190Reactive Oxygen Species as Intracellular Signaling Molecules in the Cardiovascular System
Q37376997Reactive oxygen and nitrogen species in pulmonary hypertension
Q36950679Reactive oxygen species and cellular oxygen sensing
Q34034025Reactive oxygen species and redox compartmentalization
Q34939523Reactive oxygen species and the brain in sleep apnea
Q38091647Reactive oxygen species involved in regulating fruit senescence and fungal pathogenicity
Q51588475Reactive oxygen species production and discontinuous gas exchange in insects.
Q38841868Reactive oxygen species production has a critical role in hypoxia-induced Stat3 activation and angiogenesis in human glioblastoma
Q42407109Reactive oxygen species regulate hypoxia-inducible factor 1alpha differentially in cancer and ischemia
Q40015395Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells
Q26784413Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved?
Q37560671Reactive oxygen species-dependent signaling regulates cancer
Q37962657Real-time intravital imaging of cancer models
Q37062193Redox Indicator Mice Stably Expressing Genetically Encoded Neuronal roGFP: Versatile Tools to Decipher Subcellular Redox Dynamics in Neuropathophysiology
Q92631111Redox Signaling from Mitochondria: Signal Propagation and Its Targets
Q33830140Redox control of liver function in health and disease
Q39939949Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells
Q27687119Redox modification of proteins as essential mediators of CNS autophagy and mitophagy.
Q28383361Redox regulation of mitochondrial function
Q37493001Redox regulation of mitochondrial function with emphasis on cysteine oxidation reactions
Q36642721Redox regulation of the hypoxia-inducible factor
Q39359788Redox signaling during hypoxia in mammalian cells
Q37446110Redox signaling in cardiovascular health and disease.
Q41441153Redox-optimized ROS balance: a unifying hypothesis
Q84047124Reduced O2 and elevated ROS in sea urchin embryos leads to defects in ectoderm differentiation
Q37138759Reduced liver fibrosis in hypoxia-inducible factor-1alpha-deficient mice
Q39478026Reduction of nitric oxide level enhances the radiosensitivity of hypoxic non-small cell lung cancer
Q40569602Regulation of MMP-1 expression in response to hypoxia is dependent on the intracellular redox status of metastatic bladder cancer cells.
Q43743808Regulation of SIRT3 signal related metabolic reprogramming in gastric cancer by Helicobacter pylori oncoprotein CagA.
Q36659549Regulation of angiogenesis by hypoxia and hypoxia-inducible factors
Q37415406Regulation of angiogenesis by oxygen sensing mechanisms
Q37359659Regulation of cancer cell metabolism by hypoxia-inducible factor 1.
Q38125147Regulation of cellular gas exchange, oxygen sensing, and metabolic control
Q37676060Regulation of fibroblast growth factor-2 expression in pulmonary arterial smooth muscle cells involves increased reactive oxygen species generation
Q28271592Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases
Q38302740Regulation of hypoxia-inducible factor-1a by reactive oxygen species: new developments in an old debate
Q24548975Regulation of late G1/S phase transition and APC Cdh1 by reactive oxygen species
Q34966704Regulation of life span by mitochondrial respiration: the HIF-1 and ROS connection
Q36494841Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1.
Q37461363Regulation of reactive oxygen species generation in cell signaling
Q38854862Renal Carcinogenesis, Tumor Heterogeneity, and Reactive Oxygen Species: Tactics Evolved
Q43896254Reoxygenation Reverses Hypoxic Pulmonary Arterial Remodeling by Inducing Smooth Muscle Cell Apoptosis via Reactive Oxygen Species-Mediated Mitochondrial Dysfunction
Q34258926Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells
Q39035367Responses to reductive stress in the cardiovascular system
Q34902760Retracted: Mitochondrial Dysfunction Promotes Breast Cancer Cell Migration and Invasion through HIF1α Accumulation via Increased Production of Reactive Oxygen Species
Q53415825Role of cyclophilin B in tumorigenesis and cisplatin resistance in hepatocellular carcinoma in humans.
Q46266754Role of mitochondria and mitochondria targeted agents in non-alcoholic fatty liver disease.
Q39391401Role of reactive oxygen species in the regulation of HIF-1 by prolyl hydroxylase 2 under mild hypoxia
Q37216449Role of reactive oxygen species-mediated signaling in aging.
Q46718557Roles of Neuroglobin Binding to Mitochondrial Complex III Subunit Cytochrome c1 in Oxygen-Glucose Deprivation-Induced Neurotoxicity in Primary Neurons
Q38276703S-glutathionylation reactions in mitochondrial function and disease
Q108684847SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 expression in B cells via enhancing B-cell metabolism
Q24328747SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation
Q51701430SIRT3 interactions with FOXO3 acetylation, phosphorylation and ubiquitinylation mediate endothelial cell responses to hypoxia.
Q53294437SLC4A7 sodium bicarbonate co-transporter controls mitochondrial apoptosis in ischaemic coronary endothelial cells.
Q37440350Selective accumulation of hematoporphyrin derivative in glioma through proton-coupled folate transporter SLC46A1.
Q40421377Self-clearance mechanism of mitochondrial E3 ligase MARCH5 contributes to mitochondria quality control
Q28073077Sending Out an SOS: Mitochondria as a Signaling Hub
Q34644383Serine catabolism regulates mitochondrial redox control during hypoxia
Q91809243SerpinB3 Differently Up-Regulates Hypoxia Inducible Factors -1α and -2α in Hepatocellular Carcinoma: Mechanisms Revealing Novel Potential Therapeutic Targets
Q52726988Short-term hypoxia improves early cardiac progenitor cell function in vitro.
Q34207242Signal transduction by mitochondrial oxidants
Q29615230Signal transduction by reactive oxygen species
Q36247647Signalling hypoxia by HIF hydroxylases
Q100559487Specific cyprinid HIF isoforms contribute to cellular mitochondrial regulation
Q34635842Spermidine/spermine-N1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha
Q34181294Stabilization of hypoxia-inducible factor-1alpha protein in hypoxia occurs independently of mitochondrial reactive oxygen species production.
Q89930624Stromal Hedgehog pathway activation by IHH suppresses lung adenocarcinoma growth and metastasis by limiting reactive oxygen species
Q46254809Stronger selective constraint on downstream genes in the oxidative phosphorylation pathway of cetaceans
Q24321241Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates
Q30252373Subcellular Energetics and Metabolism: A Cross-Species Framework
Q30253000Subcellular Energetics and Metabolism: Potential Therapeutic Applications
Q36900957Superoxide flashes in single mitochondria
Q36702768Superoxide generated at mitochondrial complex III triggers acute responses to hypoxia in the pulmonary circulation.
Q38001768Systems biology of antioxidants.
Q28397515TCDD induces the hypoxia-inducible factor (HIF)-1α regulatory pathway in human trophoblastic JAR cells
Q37426436Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies
Q29615491Targeting hypoxia in cancer therapy
Q53085888Targeting mitochondria by α-tocopheryl succinate overcomes hypoxia-mediated tumor cell resistance to treatment.
Q21198861Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers
Q43206778Targeting mitochondrial reactive oxygen species to modulate hypoxia-induced pulmonary hypertension
Q33799828Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing
Q27321453Tether mutations that restore function and suppress pleiotropic phenotypes of the C. elegans isp-1(qm150) Rieske iron-sulfur protein
Q33560653The Caulerpa pigment caulerpin inhibits HIF-1 activation and mitochondrial respiration
Q37799606The HIF Pathway and Erythrocytosis
Q36818360The Mitochondrial Respiratory Chain Is Required for Organismal Adaptation to Hypoxia.
Q50052210The Potential Role of Oxidative Stress in Cardiac Hypertrophy: A Narrative Review.
Q36118624The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production
Q37887129The SirT3 divining rod points to oxidative stress
Q26774894The Tumorigenic Roles of the Cellular REDOX Regulatory Systems
Q84279172The Werner syndrome gene product (WRN): a repressor of hypoxia-inducible factor-1 activity
Q35926921The absence of a mitochondrial genome in rho0 yeast cells extends lifespan independently of retrograde regulation
Q43495714The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells
Q35499600The differential role of Hif1β/Arnt and the hypoxic response in adipose function, fibrosis, and inflammation
Q46738014The expression of redox proteins in phyllodes tumor.
Q30478263The fundamental organization of cardiac mitochondria as a network of coupled oscillators
Q38051339The hypoxic testicle: physiology and pathophysiology
Q39197341The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD.
Q34038381The importance of the stem cell marker prominin-1/CD133 in the uptake of transferrin and in iron metabolism in human colon cancer Caco-2 cells
Q53513869The interplay between MYC and HIF in cancer.
Q38062538The interplay between autophagy and ROS in tumorigenesis
Q26851513The placental pursuit for an adequate oxidant balance between the mother and the fetus
Q59799827The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia
Q50062142The promise and challenges of exploiting the proton-coupled folate transporter for selective therapeutic targeting of cancer
Q36241881The relevance of molecular biomarkers in cervical cancer patients treated with radiotherapy
Q38989135The role of HIFs in ischemia-reperfusion injury.
Q48619292The role of SRC kinase in the caspase-1 pathway after hypoxia in the brain of newborn piglets
Q46978063The role of declining adaptive homeostasis in ageing
Q43252753The role of external and matrix pH in mitochondrial reactive oxygen species generation
Q42174809The role of glucose metabolism and glucose-associated signalling in cancer.
Q28390139The role of hypoxia-inducible factor-1α in zinc oxide nanoparticle-induced nephrotoxicity in vitro and in vivo
Q37079708The role of hypoxia-inducible factors in tumorigenesis.
Q28568843The role of oxidized cytochrome c in regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia
Q37494545The role of reactive oxygen species in apoptosis of the diabetic kidney.
Q28591257The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis
Q33685916The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation
Q36301932The twisted survivin connection to angiogenesis
Q39303258The use of spectroscopic imaging and mapping techniques in the characterisation and study of DLD-1 cell spheroid tumour models
Q36253857The von Hippel-Lindau protein, HIF hydroxylation, and oxygen sensing
Q36540303The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress
Q34569380The von Hippel-Lindau tumor suppressor protein: roles in cancer and oxygen sensing
Q30499819The zebrafish embryo as a dynamic model of anoxia tolerance
Q86513800Therapeutic effects of Qishen Yiqi Dropping Pill on myocardial injury induced by chronic hypoxia in rats
Q38166568Thioredoxin and Cancer: A Role for Thioredoxin in all States of Tumor Oxygenation
Q40640140Three autocrine feedback loops determine HIF1 alpha expression in chronic hypoxia.
Q39983274Thrombopoietin (TPO) regulates HIF-1alpha levels through generation of mitochondrial reactive oxygen species
Q26825809To breathe or not to breathe: the haematopoietic stem/progenitor cells dilemma
Q39357690Toxic effects of microcystin-LR on the HepG2 cell line under hypoxic and normoxic conditions
Q37366441Transcriptional regulation of yeast oxidative phosphorylation hypoxic genes by oxidative stress
Q35120832Translational and transcriptional control of Sp1 against ischaemia through a hydrogen peroxide-activated internal ribosomal entry site pathway.
Q79633258Treatment with a novel hemigramicidin-TEMPO conjugate prolongs survival in a rat model of lethal hemorrhagic shock
Q49495064Trichostatin A resistance is facilitated by HIF-1α acetylation in HeLa human cervical cancer cells under normoxic conditions
Q28087036Tumor progression and the different faces of the PERK kinase
Q37390879Tumor suppressors and cell metabolism: a recipe for cancer growth
Q37955892Tumor-stroma: In vivo assays and intravital imaging to study cell migration and metastasis
Q29248711Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer
Q24304069UCP2 inhibits ROS-mediated apoptosis in A549 under hypoxic conditions
Q58335880Uncoupling Protein 2 in Cardiovascular Health and Disease
Q90446620Unfolded protein response (UPR) integrated signaling networks determine cell fate during hypoxia
Q37787564VHL Disease
Q54943750VHL and Hypoxia Signaling: Beyond HIF in Cancer.
Q38247284Value of caveolin-1 in cancer progression and prognosis: Emphasis on cancer-associated fibroblasts, human cancer cells and mechanism of caveolin-1 expression (Review).
Q37726638Vascular rarefaction mediates whitening of brown fat in obesity.
Q39415253Virus/Host Cell Crosstalk in Hypoxic HPV-Positive Cancer Cells
Q51971299Von Hippel-Lindau disease.
Q39695742XQ2, a novel TPZ derivative, induced G2/M phase arrest and apoptosis under hypoxia in non-small cell lung cancer cells
Q34584445Zfp148 deficiency causes lung maturation defects and lethality in newborn mice that are rescued by deletion of p53 or antioxidant treatment
Q35395850microRNA-210 is upregulated in hypoxic cardiomyocytes through Akt- and p53-dependent pathways and exerts cytoprotective effects
Q28509575p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia

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