Oxidant Mechanisms in Renal Injury and Disease

scientific article

Oxidant Mechanisms in Renal Injury and Disease is …
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scholarly articleQ13442814

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P356DOI10.1089/ARS.2016.6665
P3181OpenCitations bibliographic resource ID476338
P932PMC publication ID4948213
P698PubMed publication ID26906267
P5875ResearchGate publication ID295833870

P2093author name stringMichael S Wolin
Brian B Ratliff
Wasan Abdulmahdi
Rahul Pawar
P2860cites workFree radicals and antioxidants in normal physiological functions and human diseaseQ21710698
Identification of renox, an NAD(P)H oxidase in kidneyQ22254385
Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transitionQ24301382
HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4Q24306365
The protein kinase complement of the human genomeQ24324497
Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivatorsQ24557011
Advances in mechanisms of anti-oxidationQ24704009
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1Q28131760
Effects of angiotensin II receptor blockers on diabetic nephropathyQ28251306
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alphaQ28274682
The antioxidant properties of serum albuminQ28279790
The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagyQ28280478
Oxidative stress as a major culprit in kidney disease in diabetesQ28281957
Glycosylated serum proteins and glycosylated hemoglobin in the assessment of glycemic control in insulin-dependent and non-insulin-dependent diabetes mellitusQ72867605
Nitric oxide-induced inhibition of transport by thick ascending limbs from Dahl salt-sensitive ratsQ72997608
Cytotoxic effect of autocrine and macrophage-derived nitric oxide on cultured rat mesangial cellsQ73016738
Role of lipid peroxidation, trace elements and anti-oxidant enzymes in chronic renal disease patientsQ73156807
Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): randomised placebo-controlled trialQ73176018
The balance between nitric oxide and superoxide determines apoptotic and necrotic death of rat mesangial cellsQ73326135
Nephron pO2 and renal oxygen usage in the hypertensive rat kidneyQ73338499
Localization of the thioredoxin system in normal rat kidneyQ73448152
Selective involvement of superoxide anion, but not downstream compounds hydrogen peroxide and peroxynitrite, in tumor necrosis factor-alpha-induced apoptosis of rat mesangial cellsQ73704078
Alpha-tocopherol supplementation decreases the oxidative susceptibility of LDL in renal failure patients on dialysis therapyQ73712824
The spectrum of acute renal failure in the intensive care unit compared with that seen in other settings. The Madrid Acute Renal Failure Study GroupQ74527759
Molecular mechanisms of inducible nitric oxide synthase gene expression by IL-1beta and cAMP in rat mesangial cellsQ74557578
Role of increased oxygen free radical activity in the pathogenesis of uremic hypertensionQ74601047
Transforming growth factor-beta is a potent inhibitor of extracellular matrix degradation by cultured human mesangial cellsQ77324997
Potentiation of nitric oxide synthase expression by superoxide in interleukin 1β‐stimulated rat mesangial cellsQ77357142
Nitric oxide inhibits sodium/hydrogen exchange activity in the thick ascending limbQ78253168
Redox signaling in mesangial cellsQ78461756
A JNK-Dependent Pathway Is Required for TNFα-Induced ApoptosisQ79129693
Perturbation of oxidant-antioxidant status in non-obese prehypertensive male subjectsQ79378533
Interferon-gamma enhances superoxide production in human mesangial cells via the JAK-STAT pathwayQ79839534
Albumin-bound fatty acids induce mitochondrial oxidant stress and impair antioxidant responses in proximal tubular cellsQ79894716
Novel sources of reactive oxygen species in the human bodyQ79906357
Mechanisms of cell death in oxidative stressQ36658125
The inflammatory response to ischemic acute kidney injury: a result of the 'right stuff' in the 'wrong place'?Q36733531
Role of cardiolipin in cytochrome c release from mitochondriaQ36790564
Sulforaphane attenuates gentamicin-induced nephrotoxicity: role of mitochondrial protection.Q36801830
Molecular cloning of the rat inducible nitric oxide synthase gene promoterQ36805718
Oxyl radicals, redox-sensitive signalling cascades and antioxidantsQ36849942
Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II: role in mesangial cell hypertrophy and fibronectin expressionQ36855830
Superoxide flashes in single mitochondriaQ36900957
Angiotensin II-induced reactive oxygen species and the kidneyQ36905406
Endothelial Peroxisomal Dysfunction and Impaired Pexophagy Promotes Oxidative Damage in Lipopolysaccharide-Induced Acute Kidney InjuryQ36953507
Redox control of renal function and hypertension.Q36970633
Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword?Q36989869
Hypoxia and the HIF system in kidney diseaseQ37008513
Transfer of the CYP4A region of chromosome 5 from Lewis to Dahl S rats attenuates renal injuryQ37018428
Methyl-2-acetamidoacrylate, an ethyl pyruvate analog, decreases sepsis-induced acute kidney injury in mice.Q37018467
Angiotensin II infusion induces nephrin expression changes and podocyte apoptosis.Q37071676
Thioredoxin in vascular biology: role in hypertensionQ37100218
Asymmetric dimethylarginine, oxidative stress, and vascular nitric oxide synthase in essential hypertensionQ37100474
Regulation of T-cell function by endogenously produced angiotensin II.Q37100479
Epidemiology of acute kidney injury: how big is the problem?Q37125697
Catalase and glutathione peroxidase mimicsQ37132691
Nox4 NADPH oxidase mediates peroxynitrite-dependent uncoupling of endothelial nitric-oxide synthase and fibronectin expression in response to angiotensin II: role of mitochondrial reactive oxygen speciesQ37213794
Dopamine receptors and hypertensionQ37215549
Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities.Q37245109
EMT and proteinuria as progression factorsQ37248336
Angiotensin II Type 1 Receptor Blockers Reduce Urinary Angiotensinogen Excretion and the Levels of Urinary Markers of Oxidative Stress and Inflammation in Patients with Type 2 Diabetic NephropathyQ37277601
Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS.Q37294875
Role of oxidative and nitrosative stress in cisplatin-induced nephrotoxicityQ37318389
Oxidative stress and inflammation, a link between chronic kidney disease and cardiovascular disease.Q37335062
In vivo targeting of inducible NO synthase with oligodeoxynucleotides protects rat kidney against ischemia.Q37355240
Platelet-derived growth factor and fibroblast growth factor differentially regulate interleukin 1beta- and cAMP-induced nitric oxide synthase expression in rat renal mesangial cellsQ37375753
Oxidative stress in hypertension: role of the kidneyQ37434021
Renal proximal tubular reabsorption is reduced in adult spontaneously hypertensive rats: roles of superoxide and Na+/H+ exchanger 3Q37438757
Cadmium and cellular signaling cascades: to be or not to be?Q37446113
Reduction of renal immune cell infiltration results in blood pressure control in genetically hypertensive ratsQ43852739
Enhanced nitric oxide inactivation and protein nitration by reactive oxygen species in renal insufficiencyQ43859268
Chronic treatment with a superoxide dismutase mimetic prevents vascular remodeling and progression of hypertension in salt-loaded stroke-prone spontaneously hypertensive ratsQ43874867
Expression and cellular localization of classic NADPH oxidase subunits in the spontaneously hypertensive rat kidneyQ43888058
Selective inhibition of inducible nitric oxide synthase enhances intraglomerular coagulation in chronic anti-Thy 1 nephritisQ43889603
Oxidative stress in leukocytes is a possible link between blood pressure, blood glucose, and C-reacting proteinQ43920043
Angiotensin II induces apoptosis in rat glomerular epithelial cellsQ44024826
Human neutrophils use the myeloperoxidase-hydrogen peroxide-chloride system to chlorinate but not nitrate bacterial proteins during phagocytosisQ44024880
Prognostic value of coronary vascular endothelial dysfunctionQ44090667
Overload proteinuria is followed by salt-sensitive hypertension caused by renal infiltration of immune cellsQ44174264
Hyperglycemic switch from mitochondrial nitric oxide to superoxide production in endothelial cellsQ44183059
Oxidative stress and dysregulation of superoxide dismutase and NADPH oxidase in renal insufficiencyQ44242769
Angiotensin II induces apoptosis in renal proximal tubular cellsQ44278140
Antioxidant-rich diet relieves hypertension and reduces renal immune infiltration in spontaneously hypertensive ratsQ44306702
Neutralization of the extracellular HMGB1 released by ischaemic damaged renal cells protects against renal ischaemia-reperfusion injuryQ44320666
Contributions of 20-HETE to the antihypertensive effects of Tempol in Dahl salt-sensitive ratsQ44353817
Antioxidant Activities and Oxidative Stress Byproducts in Human HypertensionQ44411446
Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicentersQ44418044
Increased renal medullary H2O2 leads to hypertensionQ44463059
Increased H(2)O(2) counteracts the vasodilator and natriuretic effects of superoxide dismutation by tempol in renal medullaQ44468829
Lipoic acid supplementation prevents angiotensin II-induced renal injuryQ44503832
Hospital-acquired renal insufficiency: a prospective studyQ44513316
Gene transfer of eNOS to the thick ascending limb of eNOS-KO mice restores the effects of L-arginine on NaCl absorptionQ44545657
Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged miceQ44609782
The effect of vitamin E supplementation on antioxidant enzyme activities and lipid peroxidation levels in hemodialysis patientsQ44668759
Determinants of platelet activation in human essential hypertensionQ44680949
Activation of the signal transducer and activator of transcription signaling pathway in renal proximal tubular cells by albuminQ44745208
Identification of manganese superoxide dismutase as a NO-regulated gene in rat glomerular mesangial cells by 2D gel electrophoresisQ44783695
Biphasic effect of hydrogen peroxide on skeletal muscle arteriolar tone via activation of endothelial and smooth muscle signaling pathwaysQ44945420
Nephropathy in Zucker diabetic fat rat is associated with oxidative and nitrosative stress: prevention by chronic therapy with a peroxynitrite scavenger ebselenQ45038702
Factors related to the impact of antihypertensive treatment in antioxidant activities and oxidative stress by-products in human hypertensionQ45056037
Attenuation of ischemia-reperfusion injury in a canine model of autologous renal transplantationQ45061944
Extracellular superoxide dismutase functions as a major repressor of hypoxia-induced erythropoietin gene expressionQ45064077
Ascorbate-dependent recycling of the vitamin E homologue Trolox by dihydrolipoate and glutathione in murine skin homogenates.Q45975964
Reactive oxygen species/oxidative stress contributes to progression of kidney fibrosis following transient ischemic injury in mice.Q46003335
Hepato and reno protective action of Calendula officinalis L. flower extract.Q46030758
Advanced lipoxidation end-products mediate lipid-induced glomerular injury: role of receptor-mediated mechanisms.Q46067855
The effect of N-acetylcysteine on proteinuria and markers of tubular injury in non-diabetic patients with chronic kidney disease. A placebo-controlled, randomized, open, cross-over studyQ46192679
Antioxidant effects of ubiquinones in microsomes and mitochondria are mediated by tocopherol recyclingQ46229565
The role of high-mobility group box-1 in renal ischemia and reperfusion injury and the effect of ethyl pyruvate.Q46369259
Vascular oxidative stress precedes high blood pressure in spontaneously hypertensive ratsQ46385767
Resveratrol, a polyphenolic phytoalexin protects against cyclosporine-induced nephrotoxicity through nitric oxide dependent mechanismQ46416889
Effects of a phenolic compound, resveratrol, on the renal function and costimulatory adhesion molecule CD86 expression in rat kidneys with ischemia/reperfusion injuryQ46435331
Angiotensin-II-induced oxidative stress elicits hypoadiponectinaemia in ratsQ46466725
Nitric oxide upregulates induction of PDGF receptor-alpha expression in rat renal mesangial cells and in anti-Thy-1 glomerulonephritisQ46472701
Role of superoxide and hydrogen peroxide in hypertension induced by an antagonist of adenosine receptors.Q46562981
Serum beta 2-microglobulin and prediction of progression to AIDS in HIV infectionQ46624575
Aldosterone stimulates reactive oxygen species production through activation of NADPH oxidase in rat mesangial cellsQ46681426
Acute reactive oxygen species (ROS)-dependent effects of IL-1β, TNF-α, and IL-6 on the glomerular filtration barrier (GFB) in vivoQ46682098
Olmesartan ameliorates progressive glomerular injury in subtotal nephrectomized rats through suppression of superoxide productionQ46687591
Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brainQ46706351
Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienolQ28298967
Regulation of RANTES and ICAM-1 expression in murine mesangial cellsQ28373148
Association of mitochondrial SOD deficiency with salt-sensitive hypertension and accelerated renal senescenceQ28512346
Subcellular localization of Nox4 and regulation in diabetesQ28566200
Nitric oxide down-regulates the expression of the catalytic NADPH oxidase subunit Nox1 in rat renal mesangial cellsQ28567734
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophagesQ28568956
Novel gp91(phox) homologues in vascular smooth muscle cells : nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathwaysQ28571066
The transcription factor ETS-1 regulates angiotensin II-stimulated fibronectin production in mesangial cellsQ28573182
Dysfunctional lysosomal autophagy leads to peroxisomal oxidative burnout and damage during endotoxin-induced stressQ28705063
ROS function in redox signaling and oxidative stressQ29615229
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensingQ29615506
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damageQ29616101
Role of free radicals and catalytic metal ions in human disease: an overviewQ29618022
Superoxide dismutase 1 limits renal microvascular remodeling and attenuates arteriole and blood pressure responses to angiotensin II via modulation of nitric oxide bioavailabilityQ30498139
Production and actions of superoxide in the renal medullaQ30662153
Increased renal medullary oxidative stress produces hypertensionQ30824863
Laser microdissection and gene expression analysis on formaldehyde-fixed archival tissueQ31034541
Induction of glia maturation factor-beta in proximal tubular cells leads to vulnerability to oxidative injury through the p38 pathway and changes in antioxidant enzyme activitiesQ31145011
Hydrogen peroxide increases extracellular matrix mRNA through TGF-beta in human mesangial cellsQ31789716
Antioxidant treatment induces transcription and expression of transforming growth factor beta in cultured renal proximal tubular cellsQ31864155
Superoxide excess in hypertension and aging: a common cause of endothelial dysfunctionQ32071845
Systematic analysis of human kinase genes: a large number of genes and alternative splicing events result in functional and structural diversityQ33229366
Inducible NO synthase: role in cellular signalling.Q33533766
Antioxidant enzymes and their implications in pathophysiologic processes.Q33541272
Edaravone directly reacts with singlet oxygen and protects cells from attackQ33547232
Duality of nitric oxide in acute renal injury.Q33607060
Induction of phagocyte cytochrome b heavy chain gene expression by interferon gammaQ33632741
PKC-alpha mediates flow-stimulated superoxide production in thick ascending limbsQ33783974
Enhanced myogenic response in the afferent arteriole of spontaneously hypertensive ratsQ33917196
A novel superoxide-producing NAD(P)H oxidase in kidneyQ33921569
Advanced glycation and lipoxidation end products: role of reactive carbonyl compounds generated during carbohydrate and lipid metabolism.Q34019427
Reactive oxygen species as glucose signaling molecules in mesangial cells cultured under high glucose.Q34039700
Angiotensin II induces nephrin dephosphorylation and podocyte injury: role of caveolin-1Q34044253
ANG II promotes autophagy in podocytesQ34085732
Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicologyQ34088828
Superoxide stimulates NaCl absorption in the thick ascending limb via activation of protein kinase CQ80071218
A quantitative approach to the free radical interaction between alpha-tocopherol or ascorbate and flavonoidsQ80090532
Protective effect of ebselen, a selenoorganic drug, against gentamicin-induced renal damage in ratsQ80162400
Promotion of oxidative stress in kidney of rats loaded with cystine dimethyl esterQ80396751
Renoprotective effect of trolox against ischaemia-reperfusion injury in ratsQ80546183
ANG II induces c-Jun NH2-terminal kinase activation and proliferation of human mesangial cells via redox-sensitive transactivation of the EGFRQ81324528
Neuroprotective effect of the free radical scavenger MCI-186 in patients with cerebral infarction: clinical evaluation using magnetic resonance imaging and spectroscopyQ81351633
Protective effect of resveratrol, a polyphenolic phytoalexin on glycerol-induced acute renal failure in rat kidneyQ82834263
Role of Intrarenal Angiotensin System Activation, Oxidative Stress, Inflammation, and Impaired Nuclear Factor-Erythroid-2-Related Factor 2 Activity in the Progression of Focal GlomerulosclerosisQ83490500
Effect of Bardoxolone Methyl on Kidney Function in Patients with T2D and Stage 3b–4 CKDQ83917014
Beneficial Effects ofN-Acetylcysteine and Ebselen on Renal Ischemia/Reperfusion InjuryQ84043125
Protective Effect of N-acetylcysteine on Early Outcomes of Deceased Renal TransplantationQ84409652
N-acetylcysteine for the management of anemia and oxidative stress in hemodialysis patientsQ84532629
The Protective Effect of Ebselen on Radiocontrast-Induced NephrotoxicityQ84769115
RAGE: a multiligand receptor contributing to the cellular response in diabetic vasculopathy and inflammationQ34113150
Nitric oxide and the regulation of gene expressionQ34134480
Amplification of nitric oxide synthase expression by nitric oxide in interleukin 1 beta-stimulated rat mesangial cellsQ34212538
Supplementation of Diets with α-Tocopherol Reduces Serum Concentrations of γ- and δ-Tocopherol in HumansQ34266433
Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ.Q34277437
A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomasQ34277465
Extracellular superoxide dismutase (SOD3): tissue-specific expression, genomic characterization, and computer-assisted sequence analysis of the human EC SOD geneQ34325577
Regulation of gene expression by nitric oxideQ34340303
α-Lipoic acid protects diabetic apolipoprotein E-deficient mice from nephropathyQ34440949
Extracellular superoxide dismutaseQ34441296
HMGB1 Contributes to Kidney Ischemia Reperfusion InjuryQ34457038
Hospital-acquired renal insufficiencyQ34522737
Changing gears in the course of glomerulonephritis by shifting superoxide to nitric oxide-dominated chemistryQ34534540
Nitric oxide in acute renal failure: NOS versus NOS.Q34534561
Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt.Q34554825
PKB and megalin determine the survival or death of renal proximal tubule cellsQ34583826
Role of nitric oxide in the regulation of nephron transportQ34588924
Reactive oxygen species production via NADPH oxidase mediates TGF-beta-induced cytoskeletal alterations in endothelial cellsQ34603387
Mitochondrial dysfunction and molecular pathways of diseaseQ34604563
Renal preservation effect of ubiquinol, the reduced form of coenzyme Q10Q34623915
HMBG1 mediates ischemia-reperfusion injury by TRIF-adaptor independent Toll-like receptor 4 signalingQ34627615
Antioxidant Therapy: Current Status and Future ProspectsQ34631489
Antioxidants, reactive oxygen and nitrogen species, gene induction and mitochondrial function.Q34701848
Peroxynitrite signaling: receptor tyrosine kinases and activation of stress-responsive pathways.Q34809217
NAD(P)H oxidase and renal epithelial ion transportQ34979579
Pathophysiology of proteinuriaQ35083600
Nitric oxide and mechanisms of redox signalingQ35182358
Reactive oxygen species-regulated signaling pathways in diabetic nephropathyQ35182363
The role of reactive oxygen species in the regulation of tubular functionQ35583103
Increase of sodium delivery stimulates the mitochondrial respiratory chain H2O2 production in rat renal medullary thick ascending limbQ35652078
Oxidative stress, renal infiltration of immune cells, and salt-sensitive hypertension: all for one and one for all.Q35682855
Oxidative stress in hypertension and chronic kidney disease: role of angiotensin II.Q35689546
Thymoquinone and curcumin attenuate gentamicin-induced renal oxidative stress, inflammation and apoptosis in rats.Q35729273
Catalase deficiency accelerates diabetic renal injury through peroxisomal dysfunctionQ35766906
Provision of antioxidant therapy in hemodialysis (PATH): a randomized clinical trialQ37604744
Interleukin 1-alpha and tumor necrosis factor-alpha induce oxygen radical production in mesangial cellsQ38147103
Nox-4 and progressive kidney diseaseQ38268776
NADPH oxidase 5 and renal disease.Q38270326
The effect of age on cyclooxygenase-2 gene expression: NF-kappaB activation and IkappaBalpha degradationQ38313494
Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharideQ38318972
Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cellsQ38352918
PREMATURE VASCULAR SENESCENCE IN METABOLIC SYNDROME: COULD IT BE PREVENTED AND REVERSED BY A SELENORGANIC ANTIOXIDANT AND PEROXYNITRITE SCAVENGER EBSELEN?Q38569611
The synthesis of sulforaphane analogues and their protection effect against cisplatin induced cytotoxicity in kidney cellsQ38932989
Suppression of Nrf2 signaling by angiotensin II in murine renal epithelial cellsQ39528046
L-carnitine attenuates oxidant injury in HK-2 cells via ROS-mitochondria pathwayQ39749317
Oxidative stress-induced necrotic cell death via mitochondira-dependent burst of reactive oxygen speciesQ39790826
Metabolic substrates, cellular energy production, and the regulation of proximal tubular transportQ39819717
The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA.Q39861713
Catalase: Physical and chemical properties, mechanism of catalysis, and physiological roleQ39990524
Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen speciesQ40046145
Aldosterone-induced increases in superoxide production counters nitric oxide inhibition of epithelial Na channel activity in A6 distal nephron cells.Q40084494
Aldosterone induces epithelial-mesenchymal transition via ROS of mitochondrial originQ40114458
Albumin overload induces adaptive responses in human proximal tubular cells through oxidative stress but not via angiotensin II type 1 receptorQ40165614
Pharmacodynamic effects of orally administered dexlipotam on endothelial function in type 2-diabetic patients.Q40179663
Mitochondrial transcription factor A induction by redox activation of nuclear respiratory factor 1.Q40361051
p38 MAP kinase inhibition ameliorates cisplatin nephrotoxicity in mice.Q40460320
Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidaseQ40467971
Radical scavenger edaravone developed for clinical use ameliorates ischemia/reperfusion injury in rat kidney.Q40566384
Docking of endothelial nitric oxide synthase (eNOS) to the mitochondrial outer membrane: a pentabasic amino acid sequence in the autoinhibitory domain of eNOS targets a proteinase K-cleavable peptide on the cytoplasmic face of mitochondriaQ40592721
Biglycan, a Nitric Oxide-regulated Gene, Affects Adhesion, Growth, and Survival of Mesangial CellsQ40651650
Up-regulation of early growth response gene-1 via the CXCR3 receptor induces reactive oxygen species and inhibits Na+/K+-ATPase activity in an immortalized human proximal tubule cell lineQ40678964
NF-kappaB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-JunQ40742264
Community-acquired acute renal failureQ40752134
Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant. Implication for inflammation-associated carcinogenesisQ40767757
Oxidative and nitrosative stress in acute renal ischemiaQ40775900
Caspases are reversibly inactivated by hydrogen peroxideQ40793718
Advanced glycation endproducts and diabetic nephropathyQ40952828
Antioxidant and redox regulation of gene transcriptionQ40989720
Total antioxidant and oxidant status of plasma and renal tissue of cisplatin-induced nephrotoxic rats: protection by floral extracts of Calendula officinalis LinnQ41172200
Cystine loading induces Fanconi's syndrome in rats: in vivo and vesicle studiesQ41510311
Establishment of a hydrogen peroxide resistant variant of renal tubular epithelial cells: role of calcium-independent phospholipase A2 in cell damageQ41573098
The renoprotective effect of curcumin in cisplatin-induced nephrotoxicity.Q41574195
Mouse extracellular superoxide dismutase: primary structure, tissue-specific gene expression, chromosomal localization, and lung in situ hybridizationQ41647830
Recycling of vitamin E in human low density lipoproteinsQ42028018
Nitric oxide inhibits glomerular TGF-beta signaling via SMOC-1.Q42079452
Effects of Trolox on the activity and gene expression of cytochrome P450 in hepatic ischemia/reperfusionQ42121169
Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine releaseQ42321499
Cyclosporin A disrupts bradykinin signaling through superoxideQ42439764
High-mobility group box 1 is a novel deacetylation target of Sirtuin1.Q42460857
Nitric oxide stimulates the stress-activated protein kinase p38 in rat renal mesangial cells.Q42467965
Oxygen-derived radicals stimulate renin release of isolated juxtaglomerular cellsQ42497139
Regulation of renin gene expression by oxidative stressQ42550738
Nitric oxide donors induce apoptosis in glomerular mesangial cells, epithelial cells and endothelial cellsQ42551700
Mitochondrial Thioredoxin: novel regulator for NADPH oxidase and angiotensin II-induced hypertensionQ42616238
Bardoxolone methyl (BARD) ameliorates aristolochic acid (AA)-induced acute kidney injury through Nrf2 pathwayQ42706839
Expression of neutrophil SOD2 is reduced after lipopolysaccharide stimulation: a potential cause of neutrophil dysfunction in chronic kidney diseaseQ42838493
Extracellular superoxide dismutase and other superoxide dismutase isoenzymes in tissues from nine mammalian speciesQ42848083
Effect of N-acetylcysteine on serum creatinine and kidney function: results of a randomized controlled trial.Q43028857
Effect of oral N-acetylcysteine treatment on plasma inflammatory and oxidative stress markers in peritoneal dialysis patients: a placebo-controlled studyQ43147200
Angiotensin II receptor blocker inhibits tumour necrosis factor-alpha-induced cell damage in human renal proximal tubular epithelial cellsQ46709561
Elevated oxidized glutathione in cystinotic proximal tubular epithelial cellsQ46734471
Byproducts of oxidative protein damage and antioxidant enzyme activities in plasma of patients with different degrees of essential hypertensionQ46845180
The determinants of endothelial dysfunction in CKD: oxidative stress and asymmetric dimethylarginineQ46867931
Albuminuria, expression of nicotinamide adenine dinucleotide phosphate oxidase and monocyte chemoattractant protein-1 in the renal tubules of hypertensive Dahl salt-sensitive ratsQ46874179
Alpha-lipoic acid protects against renal ischaemia-reperfusion injury in ratsQ46946118
Amplification of IL-1 beta-induced matrix metalloproteinase-9 expression by superoxide in rat glomerular mesangial cells is mediated by increased activities of NF-kappa B and activating protein-1 and involves activation of the mitogen-activated protQ47816419
Stress proteins in inflammation.Q47824044
Glycoxidation and inflammation in renal failure patientsQ47887980
Rat phospholipid-hydroperoxide glutathione peroxidase. cDNA cloning and identification of multiple transcription and translation start sitesQ48069265
Adrenergic responses of baroreceptive cells in the nucleus tractus solitarii of the rat: a microiontophoretic studyQ48207139
Tissue distribution of immunoreactive mouse extracellular superoxide dismutaseQ48398715
The effect of gammahydroxy-butyrate on the H-reflex: Pilot studyQ49101654
TNF-alpha and IL-1alpha induce apoptosis in subconfluent rat mesangial cells. Evidence for the involvement of hydrogen peroxide and lipid peroxidation as second messengersQ50510948
Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1.Q51089166
α-Lipoic acid protects kidney from oxidative stress and mitochondrial dysfunction associated to inflammatory conditionsQ51109825
The association between pre-hypertension status and oxidative stress markers related to atherosclerotic disease: the ATTICA studyQ51497485
High-mobility group box 1 release and redox regulation accompany regeneration and remodeling of skeletal muscleQ52607704
Hydrogen peroxide mediates a transient vasorelaxation with tempol during oxidative stress.Q53539061
Inhibition of inducible nitric oxide synthase alters Thy-1 glomeruonephritis in ratsQ53653156
Altered angiotensin II-induced small artery contraction during the development of hypertension in spontaneously hypertensive ratsQ54088022
Endothelium-derived contracting factors in resistance arteries of young spontaneously hypertensive rats before development of overt hypertensionQ54246580
Sulforaphane attenuation of experimental diabetic nephropathy involves GSK-3 beta/Fyn/Nrf2 signaling pathwayQ54287779
Synergistic induction of osteopontin by aldosterone and inflammatory cytokines in mesangial cellsQ54543449
Chronic kidney disease progressionQ55042573
Glutathione antioxidant system as a marker of oxidative stress in chronic renal failureQ57996800
N-ACETYLCYSTEINE IMPROVES THE HEMODYNAMICS AND OXIDATIVE STRESS IN HYPOXIC NEWBORN PIGS REOXYGENATED WITH 100% OXYGENQ58205764
Telmisartan Attenuates Diabetic Nephropathy by Suppressing Oxidative Stress in db/db MiceQ58366410
Atrial natriuretic peptide inhibits endothelin-1-induced activation of JNK in glomerular mesangial cellsQ61436286
Functional expression of NADPH oxidase components (alpha- and beta-subunits of cytochrome b558 and 45-kDa flavoprotein) by intrinsic human glomerular mesangial cellsQ61907383
A novel renal carbonic anhydrase type III plays a role in proximal tubule dysfunctionQ63979934
Risk factors and outcome of hospital-acquired acute renal failure. Clinical epidemiologic studyQ69106373
Effect of decreased dopamine synthesis on the development of hypertension induced by salt loading in spontaneously hypertensive ratsQ69207198
Immunolocalization of copper-zinc superoxide dismutase. II. RatQ69900567
Membrane phospholipid peroxidation in renal insufficiency and chronic hemodialysisQ70157868
The immunolocalization of copper-zinc superoxide dismutase in canine tissuesQ70292163
Urinary dopamine and sodium excretion in spontaneously hypertensive ratsQ70645772
Immunolocalization of manganese superoxide dismutase in normal and transgenic mice expressing the human enzymeQ70710995
Mechanisms of ischemic acute renal failureQ70758601
Antioxidant enzymes activity in polymorphonuclear leukocytes in chronic renal failureQ70920833
Cyclic nucleotides attenuate endothelin-1-induced activation of mitogen-activated protein kinase in cultured rat mesangial cellsQ70930590
Pathways of glutathione metabolism and transport in isolated proximal tubular cells from rat kidneyQ71226663
Antisense oligodeoxynucleotides to inducible NO synthase rescue epithelial cells from oxidative stress injuryQ71418616
Metabolic studies of rat renal tubule cells loaded with cystine: the cystine dimethylester model of cystinosisQ71788771
Induction of Nitric Oxide Synthase in Human Mesangial CellsQ72086220
The expression of NADPH oxidase components in human glomerular mesangial cells: detection of protein and mRNA for p47phox, p67phox, and p22phoxQ72125888
Oxidized LDL and lipoprotein(a) stimulate renin release of juxtaglomerular cellsQ72193005
Maillard reaction-mediated molecular damage to extracellular matrix and other tissue proteins in diabetes, aging, and uremiaQ35840907
Angiotensin II stimulates epithelial sodium channels in the cortical collecting duct of the rat kidneyQ35849490
Redox modulation of chromatin remodeling: impact on histone acetylation and deacetylation, NF-kappaB and pro-inflammatory gene expressionQ35864100
Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology.Q35913809
Angiotensin II-induced mesangial cell apoptosis: role of oxidative stress.Q36087938
Toll-like receptor 4 regulates early endothelial activation during ischemic acute kidney injuryQ36114632
Role of H2O2 in hypertension, renin‐angiotensin system activation and renal medullary disfunction caused by angiotensin IIQ36252796
Oxidative stress and nitric oxide deficiency in the kidney: a critical link to hypertension?Q36267702
HMGB1 in renal ischemic injuryQ36309461
Reactive oxygen production by cultured rat glomerular mesangial cells during phagocytosis is associated with stimulation of lipoxygenase activityQ36348317
The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orallQ36362801
Recent advances in understanding the clinical and genetic heterogeneity of Dent's disease.Q36544168
Reduced stress defense in heme oxygenase 1-deficient cells.Q36601994
Mechanisms of disease: oxidative stress and inflammation in the pathogenesis of hypertensionQ36604954
How does proteinuria cause progressive renal damage?Q36621209
Mechanisms of hydrogen-peroxide-induced biphasic response in rat mesenteric arteryQ43263476
N-acetylcysteine improves renal hemodynamics in rats with cisplatin-induced nephrotoxicity.Q43291996
Rapamycin induces the TGFbeta1/Smad signaling cascade in renal mesangial cells upstream of mTOR.Q43295562
Effects of angiotensin receptor blocker on oxidative stress and cardio-renal function in streptozotocin-induced diabetic ratsQ43299184
Nitric oxide induces MIP-2 transcription in rat renal mesangial cells and in a rat model of glomerulonephritisQ43548082
Mycophenolate mofetil prevents salt-sensitive hypertension resulting from angiotensin II exposureQ43623103
1,2-bis(2-Aminophenoxy)ethane-N,N,N',N'-tetraacetic acid induces caspase-mediated apoptosis and reactive oxygen species-mediated necrosis in cultured cortical neuronsQ43680990
NO decreases thick ascending limb chloride absorption by reducing Na(+)-K(+)-2Cl(-) cotransporter activityQ43761031
Mechanism of heme oxygenase-1 gene induction by curcumin in human renal proximal tubule cellsQ43761042
Irbesartan, an angiotensin type 1 receptor inhibitor, regulates the vascular oxidative state in patients with coronary artery diseaseQ43796478
Prognostic value of systemic endothelial dysfunction in patients with acute coronary syndromes: further evidence for the existence of the "vulnerable" patientQ43838577
Risk factors influencing survival in ICU acute renal failureQ72357093
Nitric oxide mediates immunologic injury to kidney mesangium in experimental glomerulonephritisQ72476309
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectclinical chemistryQ849994
cell biologyQ7141
P304page(s)119-46
P577publication date2016-07-20
P1433published inAntioxidants & Redox SignalingQ4775078
P1476titleOxidant Mechanisms in Renal Injury and Disease
P478volume25