HMGB1 contributes to kidney ischemia reperfusion injury

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HMGB1 contributes to kidney ischemia reperfusion injury is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1681/ASN.2009101048
P932PMC publication ID3014003
P698PubMed publication ID20847143

P2093author name stringPeng Wang
Jin Ma
Huiling Wu
Steven J Chadban
Usha Panchapakesan
Kate R Wyburn
Theresa M Corpuz
P2860cites workSignaling danger: toll-like receptors and their potential roles in kidney diseaseQ24570121
A human homologue of the Drosophila Toll protein signals activation of adaptive immunityQ28131769
Release of chromatin protein HMGB1 by necrotic cells triggers inflammationQ28131815
HMG-1 as a late mediator of endotoxin lethality in miceQ28139166
The danger model: a renewed sense of selfQ28214633
High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenalQ28242907
Decoding the patterns of self and nonself by the innate immune systemQ29618448
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGEQ29620722
Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injuryQ33381642
The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanismQ33743664
Blockade of high mobility group box-1 protein attenuates experimental severe acute pancreatitisQ33868755
The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophagesQ33895703
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidneyQ33948196
The cytokine activity of HMGB1.Q34398253
Chronic allograft nephropathy: current concepts and future directionsQ34501818
Toll-like receptors in systemic autoimmune diseaseQ34576448
TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathwaysQ34625047
Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantationQ34945273
Pattern recognition receptors: doubling up for the innate immune responseQ35036522
Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shockQ35052743
Reversing established sepsis with antagonists of endogenous high-mobility group box 1.Q35122534
Ischemic acute renal failure: an inflammatory disease?Q35836380
TLR4 activation mediates kidney ischemia/reperfusion injuryQ35987574
A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA.Q35990737
HMGB1 release induced by liver ischemia involves Toll-like receptor 4 dependent reactive oxygen species production and calcium-mediated signalingQ36229208
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusionQ36403403
Heat shock protein gp96 interacts with protein phosphatase 5 and controls toll-like receptor 2 (TLR2)-mediated activation of extracellular signal-regulated kinase (ERK) 1/2 in post-hypoxic kidney cellsQ37169564
MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cellsQ38147109
Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injuryQ38278784
HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.Q40249835
Predominant role for C5b-9 in renal ischemia/reperfusion injury.Q40437461
HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathwayQ40751242
Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cellsQ40799740
Effects of initial ischemia/reperfusion injury on the transplanted kidneyQ41650470
Do alloreactivity and prolonged cold ischemia cause different elementary lesions in chronic allograft nephropathy?Q42702615
Resident dendritic cells prevent postischemic acute renal failure by help of single Ig IL-1 receptor-related protein.Q43289466
Nonhistone Proteins HMG 1 and HMG 2 Change the DNA Helical StructureQ44863866
Macrophages contribute to the initiation of ischaemic acute renal failure in ratsQ46892805
Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responsesQ47421290
Hemorrhage-induced acute lung injury is TLR-4 dependentQ47794695
HMGB1 contributes to the development of acute lung injury after hemorrhageQ47868867
Complement factor C5a mediates renal ischemia-reperfusion injury independent from neutrophils.Q48024813
Anti-high-mobility group box chromosomal protein 1 antibodies improve survival of rats with sepsis.Q53610623
The Toll-IL-1R Member Tir8/SIGIRR Negatively Regulates Adaptive Immunity against Kidney GraftsQ56942637
High mobility group protein 1 (HMGB1) quantified by ELISA with a monoclonal antibody that does not cross-react with HMGB2Q73827594
HMG-1 as a mediator of acute lung inflammationQ74279708
In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-gamma and TNF-alpha mediated up-regulation during inflammationQ77522414
Ischemia-reperfusion injury activates innate immunity in rat kidneysQ81778100
Cutting edge: high-mobility group box 1 preconditioning protects against liver ischemia-reperfusion injuryQ83918073
P433issue11
P921main subjectreperfusion injuryQ1413991
P304page(s)1878-1890
P577publication date2010-09-16
P1433published inJournal of the American Society of NephrologyQ17123893
P1476titleHMGB1 contributes to kidney ischemia reperfusion injury
P478volume21

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cites work (P2860)
Q47096387A tissue-specific role for Nlrp3 in tubular epithelial repair after renal ischemia/reperfusion
Q50175524AKI on CKD: heightened injury, suppressed repair, and the underlying mechanisms.
Q37162933ATF3 Protects against LPS-Induced Inflammation in Mice via Inhibiting HMGB1 Expression
Q36280335Absence of MyD88 signaling induces donor-specific kidney allograft tolerance
Q37950251Acute kidney injury: a conspiracy of Toll-like receptor 4 on endothelia, leukocytes, and tubules.
Q47630229Adiponectin suppression of late inflammatory mediator, HMGB1-induced cytokine expression in RAW264 macrophage cells
Q35930160An ongoing search for potential targets and therapies for lethal sepsis
Q35692937An update on the role of the inflammasomes in the pathogenesis of kidney diseases
Q36940938Bax and Bak have critical roles in ischemic acute kidney injury in global and proximal tubule-specific knockout mouse models
Q46589921Beneficial Effects of Necrosis Modulator, Indole Derivative NecroX-7, on Renal Ischemia-Reperfusion Injury in Rats.
Q38206875Beyond tissue injury-damage-associated molecular patterns, toll-like receptors, and inflammasomes also drive regeneration and fibrosis
Q33752945Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury.
Q53516911Blockade of Extracellular HMGB1 Suppresses Xenoreactive B Cell Responses and Delays Acute Vascular Xenogeneic Rejection.
Q54967677Blockade of HMGB1 Attenuates Diabetic Nephropathy in Mice.
Q36904960Blue light reduces organ injury from ischemia and reperfusion
Q93052193Bombardier Enables Delivery of Short-Form Bomanins in the Drosophila Toll Response
Q51281990Carbon monoxide inhibits the nuclear-cytoplasmic translocation of HMGB1 in an in vitro oxidative stress injury model of mouse renal tubular epithelial cells.
Q87595135Carbon monoxide potently prevents ischemia-induced high-mobility group box 1 translocation and release and protects against lethal renal ischemia-reperfusion injury
Q35527551Circulating Mitochondrial DAMPs Are Not Effective Inducers of Proteinuria and Kidney Injury in Rodents
Q35210800Cisplatin induces primary necrosis through poly(ADP-ribose) polymerase 1 activation in kidney proximal tubular cells
Q36119405Complement activation and toll-like receptor-2 signaling contribute to cytokine production after renal ischemia/reperfusion
Q64057278Complement-mediated Damage to the Glycocalyx Plays a Role in Renal Ischemia-reperfusion Injury in Mice
Q90318136DAMP-sensing receptors in sterile inflammation and inflammatory diseases
Q38113929Danger control programs cause tissue injury and remodeling.
Q47931207Diabetes increases the susceptibility to acute kidney injury after myocardial infarction through augmented activation of renal Toll-like receptors in rats.
Q35169612Differential activation of Toll-like receptor-mediated apoptosis induced by hypoxia
Q28237208Dipeptidyl peptidase IV inhibitor protects against renal interstitial fibrosis in a mouse model of ureteral obstruction
Q37739688Down-regulation of nuclear HMGB1 reduces ischemia-induced HMGB1 translocation and release and protects against liver ischemia-reperfusion injury
Q36089059Early interleukin 6 production by leukocytes during ischemic acute kidney injury is regulated by TLR4.
Q36403585Endothelial pentraxin 3 contributes to murine ischemic acute kidney injury
Q65000173Ethyl Pyruvate Directly Attenuates Active Secretion of HMGB1 in Proximal Tubular Cells via Induction of Heme Oxygenase-1.
Q47273397Evaluation of metabolomic profiling against renal toxicity in Sprague-Dawley rats treated with melamine and cyanuric acid
Q42241986Exogenous MSCs ameliorate hypoxia/reoxygenation injury in renal tubular epithelial cells through JAK/STAT signaling pathway-mediated regulation of HMGB1.
Q38944042Extracellular nucleotides from dying cells act as molecular signals to promote wound repair in renal tubular injury.
Q59812451FGF10 Protects Against Renal Ischemia/Reperfusion Injury by Regulating Autophagy and Inflammatory Signaling
Q93164918Fibroblast Growth Factors in the Management of Acute Kidney Injury Following Ischemia-Reperfusion
Q39603954Four danger response programs determine glomerular and tubulointerstitial kidney pathology: clotting, inflammation, epithelial and mesenchymal healing
Q37148892G protein α12 (Gα12) is a negative regulator of kidney injury molecule-1-mediated efferocytosis
Q26851850Guidance cue netrin-1 and the regulation of inflammation in acute and chronic kidney disease
Q35758460HCaRG accelerates tubular repair after ischemic kidney injury
Q34801048HMGB1 exacerbates renal tubulointerstitial fibrosis through facilitating M1 macrophage phenotype at the early stage of obstructive injury
Q34622835HMGB1 in health and disease
Q38203471HMGB1 in hormone-related cancer: a potential therapeutic target
Q36309461HMGB1 in renal ischemic injury
Q35919099HMGB1 is activated in type 2 diabetes mellitus patients and in mesangial cells in response to high glucose
Q36758021HMGB1 mediates anemia of inflammation in murine sepsis survivors.
Q35899312HMGB1 promotes the activation of NLRP3 and caspase-8 inflammasomes via NF-κB pathway in acute glaucoma
Q51673193HMGB1/TLR4 signaling induces an inflammatory response following high-pressure renal pelvic perfusion in a porcine model.
Q92126449High Mobility Group Box 1 Mediates TMAO-Induced Endothelial Dysfunction
Q55314635High Mobility Group Box 1 Promotes Aortic Calcification in Chronic Kidney Disease via the Wnt/β-Catenin Pathway.
Q42460857High-mobility group box 1 is a novel deacetylation target of Sirtuin1.
Q92088123High-mobility group box 1 protein antagonizes the immunosuppressive capacity and therapeutic effect of mesenchymal stem cells in acute kidney injury
Q42245543Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4.
Q47161100How Mucosal Epithelia Deal with Stress: Role of NKG2D/NKG2D Ligands during Inflammation.
Q27016140How the Innate Immune System Senses Trouble and Causes Trouble
Q52767331Human CD200 suppresses macrophage-mediated xenogeneic cytotoxicity and phagocytosis.
Q38261586Immune cells in experimental acute kidney injury
Q37991781Immunotherapy for acute kidney injury
Q38832656Inflammasomes in the urinary tract: a disease-based review
Q38187172Inflammatory triggers of acute rejection of organ allografts.
Q91645355Influence of Hypoxic Preservation Temperature on Endothelial Cells and Kidney Integrity
Q36939146Inhibition of Toll-Like Receptor 4 Signaling Mitigates Microvascular Loss but Not Fibrosis in a Model of Ischemic Acute Kidney Injury
Q38808100Innate immune mechanisms in transplant allograft vasculopathy
Q36420171Innate immunity and organ transplantation: focus on lung transplantation
Q35889959Innate immunity in donor procurement
Q38341632Innate immunity in solid organ transplantation: an update and therapeutic opportunities
Q43099963Innate versus adaptive immunity in kidney immunopathology.
Q35849502Interaction between uric acid and HMGB1 translocation and release from endothelial cells
Q94415367Ionizing Radiation Induces HMGB1 Cytoplasmic Translocation and Extracellular Release
Q38690664Ischaemic and inflammatory injury in renal graft from brain death donation: an update review.
Q37578502Kidney protection by hypothermic total liquid ventilation after cardiac arrest in rabbits
Q91776030Landscape of innate immune system transcriptome and acute T cell-mediated rejection of human kidney allografts
Q38692356Links between coagulation, inflammation, regeneration, and fibrosis in kidney pathology.
Q48189798Luteolin Treatment Protects against Renal Ischemia-Reperfusion Injury in Rats
Q53188377MDM2 (murine double minute-2) links inflammation and tubular cell healing during acute kidney injury in mice.
Q28068907Macrophage in chronic kidney disease
Q37524085Macrophage phenotype controls long-term AKI outcomes--kidney regeneration versus atrophy
Q38453872Macrophages in kidney injury, inflammation, and fibrosis
Q88392842Macrophages play an essential role in trauma-induced sterile inflammation and tissue repair
Q91259809Macrophages: versatile players in renal inflammation and fibrosis
Q39012703Mechanisms of graft rejection after lung transplantation
Q33623118Melatonin promoted renal regeneration in folic acid-induced acute kidney injury via inhibiting nucleocytoplasmic translocation of HMGB1 in tubular epithelial cells
Q98177680Metabolic Flexibility and Innate Immunity in Renal Ischemia Reperfusion Injury: The Fine Balance Between Adaptive Repair and Tissue Degeneration
Q33751106Molecular mechanism and therapeutic modulation of high mobility group box 1 release and action: an updated review
Q46471622Mycophenolate mofetil improves renal haemodynamics, microvascular oxygenation, and inflammation in a rat model of supra-renal aortic clamping-mediated renal ischaemia reperfusion injury
Q36363349NKT cell modulates NAFLD potentiation of metabolic oxidative stress-induced mesangial cell activation and proximal tubular toxicity
Q38861198Necroptosis: A Novel Cell Death Modality and Its Potential Relevance for Critical Care Medicine.
Q27009468Novel Mechanisms of Herbal Therapies for Inhibiting HMGB1 Secretion or Action
Q28384392Oxidant Mechanisms in Renal Injury and Disease
Q27000955Oxidative stress-mediated HMGB1 biology
Q38217071Pattern recognition receptors and the inflammasome in kidney disease.
Q34493096Placental growth factor, pregnancy-associated plasma protein-A, soluble receptor for advanced glycation end products, extracellular newly identified receptor for receptor for advanced glycation end products binding protein and high mobility group bo
Q90686395Plasma From Patients Undergoing Liver Transplantation Is Resistant to Anticoagulant Activity of Soluble Thrombomodulin
Q54420635Preconditioning with recombinant high-mobility group box 1 protein protects the kidney against ischemia-reperfusion injury in mice.
Q41330901Pretreatment of cisplatin in recipients attenuates post-transplantation pancreatitis in murine model
Q38135408Processes of sterile inflammation.
Q51023205Protective effects and mechanisms of Shenhua Tablet () on toll-like receptors in rat model of renal ischemia-reperfusion injury.
Q34497328Proximal tubule epithelial cell specific ablation of the spermidine/spermine N1-acetyltransferase gene reduces the severity of renal ischemia/reperfusion injury
Q57809696Pyroptosis versus necroptosis: similarities, differences, and crosstalk
Q54240458RIPK3-mediated necroptosis promotes donor kidney inflammatory injury and reduces allograft survival.
Q99238602Recent Advances in the Role of Natural Killer Cells in Acute Kidney Injury
Q92643552Recombinant thrombomodulin prevents acute lung injury induced by renal ischemia-reperfusion injury
Q38065649Regulation of wound healing and organ fibrosis by toll-like receptors.
Q44911053Report of the second joint meeting of ESOT and AST: current pipelines in biotech and pharma
Q37587328Requirement for TLR2 in the development of albuminuria, inflammation and fibrosis in experimental diabetic nephropathy
Q38042110Role of GLP-1 and DPP-4 in diabetic nephropathy and cardiovascular disease
Q38793108Role of TLRs and DAMPs in allograft inflammation and transplant outcomes.
Q37707474Role of Toll-like receptor-4 in renal graft ischemia-reperfusion injury.
Q38184614Role of Toll-like receptors in diabetic nephropathy
Q38199750Role of high mobility group box 1 and its signaling pathways in renal diseases
Q36884814Role of warm ischemia on innate and adaptive responses in a preclinical renal auto-transplanted porcine model
Q99591829SHP2 inhibitor PHPS1 ameliorates acute kidney injury by Erk1/2-STAT3 signaling in a combined murine hemorrhage followed by septic challenge model
Q35596539Serum-stabilized naked caspase-3 siRNA protects autotransplant kidneys in a porcine model
Q36885661Signaling of high mobility group box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14.
Q38245855Strategies to optimize kidney recovery and preservation in transplantation: specific aspects in pediatric transplantation
Q47736069Strong renal expression of heat shock protein 70, high mobility group box 1, inducible nitric oxide synthase, and nitrotyrosine in mice model of severe malaria
Q38766473TLR-Induced Murine Dendritic Cell (DC) Activation Requires DC-Intrinsic Complement.
Q33633050TLR4 activation promotes podocyte injury and interstitial fibrosis in diabetic nephropathy
Q51538354TLR4-mediated inflammation is a key pathogenic event leading to kidney damage and fibrosis in cyclosporine nephrotoxicity.
Q36344904Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis
Q28085089The HMGB1-RAGE Inflammatory Pathway: Implications for Brain Injury-Induced Pulmonary Dysfunction
Q38646389The Mononuclear Phagocyte System in Organ Transplantation.
Q99712217The Yin and Yang of Alarmins in Regulation of Acute Kidney Injury
Q35106252The alarmin concept applied to human renal transplantation: evidence for a differential implication of HMGB1 and IL-33
Q38174491The gut-renal axis: do incretin-based agents confer renoprotection in diabetes?
Q35519094The high-mobility group box-1 nuclear factor mediates retinal injury after ischemia reperfusion.
Q52900630The protective effect of neutralizing high-mobility group box1 against chronic cyclosporine nephrotoxicity in mice.
Q89871246The protective effect of uric acid in reducing TLR4/NF-κB activation through the inhibition of HMGB1 acetylation in a model of ischemia-reperfusion injury in vitro
Q27024367The renal mononuclear phagocytic system
Q34236827The role of SDF-1-CXCR4/CXCR7 axis in the therapeutic effects of hypoxia-preconditioned mesenchymal stem cells for renal ischemia/reperfusion injury
Q38850055The role of Toll-like receptor 4 (TLR4) in cardiac ischaemic-reperfusion injury, cardioprotection and preconditioning
Q39168114The role of Toll-like receptor proteins (TLR) 2 and 4 in mediating inflammation in proximal tubules
Q26749818The role of high mobility group box 1 (HMGB1) in the pathogenesis of kidney diseases
Q88671029The role of platelets in acute kidney injury
Q30275901The spleen contributes importantly to myocardial infarct exacerbation during post-ischemic reperfusion in mice via signaling between cardiac HMGB1 and splenic RAGE.
Q28305924Therapeutic inflammatory monocyte modulation using immune-modifying microparticles
Q42316686Toll-like receptor 2 agonist exacerbates renal injury in diabetic mice
Q53641263Toll-like receptor 4 is involved in renoprotective effect of ischemic postconditioning after renal ischemia/reperfusion injury in rats.
Q35720839Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy
Q37733573Toll-like receptor 4-induced IL-22 accelerates kidney regeneration.
Q37980655Toll-like receptors in transplantation: sensing and reacting to injury
Q37297556Toll‑like receptor 4 contributes to acute kidney injury after cardiopulmonary resuscitation in mice
Q90332833Trained immunity in organ transplantation
Q39911374Upregulation of IL-1β, IL-6, and CCL-2 by a novel mouse model of pancreatic ischemia-reperfusion injury
Q36380486Upregulation of TLR4 via PKC activation contributes to impaired wound healing in high-glucose-treated kidney proximal tubular cells
Q95840792Vascular Signaling in Allogenic Solid Organ Transplantation - The Role of Endothelial Cells
Q37449283Xenon treatment protects against cold ischemia associated delayed graft function and prolongs graft survival in rats.

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