TLR4 activation promotes podocyte injury and interstitial fibrosis in diabetic nephropathy

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TLR4 activation promotes podocyte injury and interstitial fibrosis in diabetic nephropathy is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...997985M
P356DOI10.1371/JOURNAL.PONE.0097985
P932PMC publication ID4026484
P698PubMed publication ID24842252
P5875ResearchGate publication ID262540043

P2093author name stringTony Kwan
Jin Ma
Huiling Wu
Cathy Y Zhao
Carol A Pollock
Xiaochen Chen
Steven J Chadban
Usha Panchapakesan
P2860cites workSignaling danger: toll-like receptors and their potential roles in kidney diseaseQ24570121
Expression of podocyte-associated molecules in acquired human kidney diseasesQ28188737
Transforming growth factor beta in tissue fibrosisQ28239292
TLR4 enhances TGF-beta signaling and hepatic fibrosisQ29620016
Increased toll-like receptor (TLR) activation and TLR ligands in recently diagnosed type 2 diabetic subjectsQ33751565
The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophagesQ33895703
The early natural history of nephropathy in type 1 diabetes: I. Study design and baseline characteristics of the study participants.Q53315483
Toll-Like Receptor 4 Mediates Maladaptive Left Ventricular Remodeling and Impairs Cardiac Function After Myocardial InfarctionQ59981285
Exacerbation of diabetic nephropathy by hyperlipidaemia is mediated by Toll-like receptor 4 in miceQ61648712
Morphometric analysis of cellular infiltration assessed by monoclonal antibody labeling in sequential human renal allograft biopsiesQ70307331
A principle for counting tissue structures on random sectionsQ76418947
Toll-like receptor 4 ligation on intrinsic renal cells contributes to the induction of antibody-mediated glomerulonephritis via CXCL1 and CXCL2Q80219173
Linking metabolism and immunology: diabetic nephropathy is an inflammatory diseaseQ81716398
Toll-like receptor 2 agonists exacerbate accelerated nephrotoxic nephritisQ83886184
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidneyQ33948196
TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injuryQ34124196
HMGB1 contributes to kidney ischemia reperfusion injuryQ34457038
The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potentialQ34527184
From fibrosis to sclerosis: mechanisms of glomerulosclerosis in diabetic nephropathyQ34554570
Knockout of toll-like receptor-2 attenuates both the proinflammatory state of diabetes and incipient diabetic nephropathyQ35143026
Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathyQ35720839
TLR4 activation mediates kidney ischemia/reperfusion injuryQ35987574
Chronic kidney disease in the general populationQ36047316
Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory stateQ36459935
Inflammation and diabetic nephropathyQ36659502
TLR4 signaling mediates inflammation and tissue injury in nephrotoxicityQ36662114
TLR4 links podocytes with the innate immune system to mediate glomerular injuryQ36666867
Role of macrophages in complications of type 2 diabetesQ36916949
Estimating podocyte number and density using a single histologic sectionQ37733611
Macrophages and renal fibrosisQ37771627
Caught flat-footed: podocyte damage and the molecular bases of focal glomerulosclerosisQ39912818
HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.Q40249835
Roles of toll-like receptors in C-C chemokine production by renal tubular epithelial cellsQ40712456
HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathwayQ40751242
Podocyte number predicts long-term urinary albumin excretion in Pima Indians with Type II diabetes and microalbuminuriaQ40790842
Toll-like receptor 4: a novel signaling pathway during renal fibrogenesisQ41204968
A new method for large scale isolation of kidney glomeruli from miceQ42047954
Renal protective effects of toll-like receptor 4 signaling blockade in type 2 diabetic mice.Q42823402
Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetesQ43565027
Alpha-lipoic acid attenuates hyperglycemia and prevents glomerular mesangial matrix expansion in diabetesQ43829978
The TLR4 antagonist CRX-526 protects against advanced diabetic nephropathy.Q45903757
Antibody blockade of c-fms suppresses the progression of inflammation and injury in early diabetic nephropathy in obese db/db miceQ47733423
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue5
P407language of work or nameEnglishQ1860
P921main subjecttoll-like receptorQ408004
P304page(s)e97985
P577publication date2014-05-19
P1433published inPLOS OneQ564954
P1476titleTLR4 activation promotes podocyte injury and interstitial fibrosis in diabetic nephropathy
P478volume9

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cites work (P2860)
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