| scholarly article | Q13442814 |
| P50 | author | Liliana Schaefer | Q55296508 |
| Ramanjaneyulu Allam | Q42134972 | ||
| P2093 | author name string | Hans-Joachim Anders | |
| Shrikant R Mulay | |||
| Kristin Moreth | |||
| Marc Monestier | |||
| Bernd Hohenstein | |||
| Christian Hugo | |||
| Helen Liapis | |||
| Fritz Krombach | |||
| Julia Lichtnekert | |||
| Mi Ryu | |||
| Bernd Uhl | |||
| Christoph A Reichel | |||
| Christina Rebecca Scherbaum | |||
| Claudia Schwarzenberger | |||
| Holger Hägele | |||
| Jan Henrik Hagemann | |||
| Khader Valli Rupanagudi | |||
| Murthy Narayana Darisipudi | |||
| P2860 | cites work | Ischemia reperfusion induces IFN regulatory factor 4 in renal dendritic cells, which suppresses postischemic inflammation and prevents acute renal failure | Q42986642 |
| Sepsis: the dark side of histones | Q43247465 | ||
| Bacterial lipopeptide triggers massive albuminuria in murine lupus nephritis by activating Toll-like receptor 2 at the glomerular filtration barrier | Q43744733 | ||
| Inhibition of Toll-like receptors TLR4 and 7 signaling pathways by SIGIRR: a computational approach. | Q43807287 | ||
| Role of TLR1 and TLR6 in the host defense against disseminated candidiasis | Q44211471 | ||
| Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway | Q45178588 | ||
| Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice | Q47200145 | ||
| Toll-like receptor-2 modulates ventricular remodeling after myocardial infarction. | Q47341057 | ||
| Isolation, culture, and characterization of endothelial cells from mouse glomeruli | Q47588468 | ||
| Structure and binding properties of monoclonal antibodies to core histones from autoimmune mice | Q48107620 | ||
| CD14-dependent and CD14-independent signaling pathways in murine macrophages from normal and CD14 knockout mice stimulated with lipopolysaccharide or taxol. | Q52525157 | ||
| In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-gamma and TNF-alpha mediated up-regulation during inflammation | Q77522414 | ||
| Unresponsiveness of MyD88-deficient mice to endotoxin | Q78093558 | ||
| Spiegelmer inhibition of CCL2/MCP-1 ameliorates lupus nephritis in MRL-(Fas)lpr mice | Q80598527 | ||
| Chemokine receptors Ccr1, Ccr2, and Ccr5 mediate neutrophil migration to postischemic tissue | Q81455010 | ||
| Postischemic vascular permeability requires both TLR-2 and TLR-4, but only TLR-2 mediates the transendothelial migration of leukocytes | Q82603912 | ||
| First responders: understanding monocyte-lineage traffic in the acutely injured kidney | Q82729619 | ||
| Trif is not required for immune complex glomerulonephritis: dying cells activate mesangial cells via Tlr2/Myd88 rather than Tlr3/Trif | Q83214030 | ||
| Cutting edge: cyclic polypeptide and aminoglycoside antibiotics trigger IL-1β secretion by activating the NLRP3 inflammasome | Q83324869 | ||
| Toll-like receptors and danger signaling in kidney injury | Q84586593 | ||
| Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis | Q24606320 | ||
| Release of chromatin protein HMGB1 by necrotic cells triggers inflammation | Q28131815 | ||
| Protein-binding assays in biological liquids using microscale thermophoresis | Q28296871 | ||
| Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components | Q28511151 | ||
| Identification of Lps2 as a key transducer of MyD88-independent TIR signalling | Q28587545 | ||
| Netting neutrophils in autoimmune small-vessel vasculitis | Q29615432 | ||
| How dying cells alert the immune system to danger | Q29615501 | ||
| Enhanced progenitor cell recruitment and endothelial repair after selective endothelial injury of the mouse kidney | Q30494903 | ||
| The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages | Q33895703 | ||
| The nucleosome (histone-DNA complex) is the TLR9-specific immunostimulatory component of Plasmodium falciparum that activates DCs. | Q33936854 | ||
| Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney | Q33948196 | ||
| Extracellular histones are major mediators of death in sepsis | Q34019901 | ||
| HMGB1 contributes to kidney ischemia reperfusion injury | Q34457038 | ||
| TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways | Q34625047 | ||
| Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury | Q35175597 | ||
| Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice | Q35541859 | ||
| Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9. | Q35629356 | ||
| Mdm2 promotes systemic lupus erythematosus and lupus nephritis | Q35758450 | ||
| Ischemic acute renal failure: an inflammatory disease? | Q35836380 | ||
| Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits | Q35963056 | ||
| TLR4 activation mediates kidney ischemia/reperfusion injury | Q35987574 | ||
| Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens. | Q36851869 | ||
| Potential roles of histones in host defense as antimicrobial agents | Q37265041 | ||
| Inhibiting glycogen synthase kinase-3 reduces endotoxaemic acute renal failure by down-regulating inflammation and renal cell apoptosis | Q37332647 | ||
| NETs: a new strategy for using old weapons | Q37584656 | ||
| The sterile inflammatory response | Q37716003 | ||
| Sepsis and acute kidney injury | Q37874863 | ||
| The role of interstitial macrophages in nephropathy of type 2 diabetic db/db mice. | Q40153047 | ||
| Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein | Q40609759 | ||
| Roles of toll-like receptors in C-C chemokine production by renal tubular epithelial cells | Q40712456 | ||
| Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response | Q40899986 | ||
| Double-stranded DNA activates glomerular endothelial cells and enhances albumin permeability via a toll-like receptor-independent cytosolic DNA recognition pathway. | Q41937471 | ||
| P433 | issue | 8 | |
| P921 | main subject | toll-like receptor | Q408004 |
| kidney disease | Q1054718 | ||
| P304 | page(s) | 1375-1388 | |
| P577 | publication date | 2012-06-07 | |
| P1433 | published in | Journal of the American Society of Nephrology | Q17123893 |
| P1476 | title | Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4. | |
| P478 | volume | 23 |
| Q59805856 | A Comparative Review of Neutrophil Extracellular Traps in Sepsis |
| Q35029014 | A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI. |
| Q33438974 | AN INVESTIGATION OF EXTRACELLULAR HISTONES IN PIG-TO-BABOON ORGAN XENOTRANSPLANTATION. |
| Q41673025 | Acetylated Histones in Apoptotic Microparticles Drive the Formation of Neutrophil Extracellular Traps in Active Lupus Nephritis. |
| Q93014132 | Activation of Myd88-Dependent TLRs Mediates Local and Systemic Inflammation in a Mouse Model of Primary Sjögren's Syndrome |
| Q33800669 | Acute kidney injury: what part do toll-like receptors play? |
| Q35582774 | Acute lung injury and the role of histones |
| Q35692937 | An update on the role of the inflammasomes in the pathogenesis of kidney diseases |
| Q40398984 | Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury |
| Q95277397 | Association of Prenatal Exposure to Ambient Air Pollution With Circulating Histone Levels in Maternal Cord Blood |
| Q38206875 | Beyond tissue injury-damage-associated molecular patterns, toll-like receptors, and inflammasomes also drive regeneration and fibrosis |
| Q33752945 | Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury. |
| Q27005610 | Biological interplay between proteoglycans and their innate immune receptors in inflammation |
| Q57141152 | Biology, role and therapeutic potential of circulating histones in acute inflammatory disorders |
| Q28293202 | Blebs produced by actin-myosin contraction during apoptosis release damage-associated molecular pattern proteins before secondary necrosis occurs |
| Q38136506 | Canonical and non-canonical effects of the NLRP3 inflammasome in kidney inflammation and fibrosis. |
| Q90397255 | Carbocisteine inhibits the expression of Muc5b in COPD mouse model |
| Q90259238 | Chronic Critical Illness and the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome |
| Q59808977 | Circulating histone H3 levels are increased in septic mice in a neutrophil-dependent manner: preclinical evaluation of a novel sandwich ELISA for histone H3 |
| Q37330936 | Circulating histones are major mediators of systemic inflammation and cellular injury in patients with acute liver failure |
| Q45359126 | Circulating histones exacerbate inflammation in mice with acute liver failure |
| Q48649413 | Circulating histones for predicting prognosis after cardiac surgery: a prospective study. |
| Q92381713 | Comparison of UV spectrometry and fluorometry-based methods for quantification of cell-free DNA in red cell components |
| Q50003562 | Comparison of acute kidney injury of different aetiology reveals in-common mechanisms of tissue damage. |
| Q38267715 | Complexity of danger: the diverse nature of damage-associated molecular patterns. |
| Q33771778 | Critical role for the NLRP3 inflammasome during acute lung injury |
| Q47817260 | DC-SIGN reacts with TLR-4 and regulates inflammatory cytokine expression via NF-κB activation in renal tubular epithelial cells during acute renal injury. |
| Q89777631 | DNA and factor VII-activating protease protect against the cytotoxicity of histones |
| Q27334890 | Damage-associated molecular pattern-activated neutrophil extracellular trap exacerbates sterile inflammatory liver injury |
| Q90707412 | Damage-associated molecular patterns in trauma |
| Q38113929 | Danger control programs cause tissue injury and remodeling. |
| Q55355541 | Danger signals in trauma. |
| Q38310937 | Dendritic Cells and Macrophages: Sentinels in the Kidney |
| Q90401398 | Detrimental Effect of Type I IFNs During Acute Lung Infection With Pseudomonas aeruginosa Is Mediated Through the Stimulation of Neutrophil NETosis |
| Q61795797 | Dexmedetomidine inhibits astrocyte pyroptosis and subsequently protects the brain in in vitro and in vivo models of sepsis |
| Q47931207 | Diabetes increases the susceptibility to acute kidney injury after myocardial infarction through augmented activation of renal Toll-like receptors in rats. |
| Q56172333 | Disseminated intravascular coagulation |
| Q39242400 | Drosophila Malpighian Tubules: A Model for Understanding Kidney Development, Function, and Disease |
| Q43229489 | Dying cells and extracellular histones in AKI: beyond a NET effect? |
| Q38689845 | Dynamic interactions of Plasmodium spp. with vascular endothelium |
| Q52324051 | Elevated extracellular nucleosomes and their relevance to inflammation in stage 5 chronic kidney disease. |
| Q41750924 | Elevated levels of circulating histones indicate disease activity in patients with hand, foot, and mouth disease (HFMD). |
| Q40365709 | Enhanced activation of dendritic cells by autologous apoptotic microvesicles in MRL/lpr mice |
| Q47108823 | Experimental blunt chest trauma-induced myocardial inflammation and alteration of gap-junction protein connexin 43. |
| Q38543321 | Extracellular DNA and histones: double-edged swords in immunothrombosis |
| Q92860794 | Extracellular DNA traps in inflammation, injury and healing |
| Q90706404 | Extracellular Histones Activate Plasma Membrane Toll-Like Receptor 9 to Trigger Calcium Oscillations in Rat Pancreatic Acinar Tumor Cell AR4-2J |
| Q37327503 | Extracellular histones are essential effectors of C5aR- and C5L2-mediated tissue damage and inflammation in acute lung injury |
| Q41247478 | Extracellular histones disarrange vasoactive mediators release through a COX-NOS interaction in human endothelial cells. |
| Q38202562 | Extracellular histones in tissue injury and inflammation |
| Q49525696 | Extracellular histones induce erythrocyte fragility and anemia. |
| Q38811965 | Extracellular histones reduce survival and angiogenic responses of late outgrowth progenitor and mature endothelial cells |
| Q39032748 | Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation |
| Q38944042 | Extracellular nucleotides from dying cells act as molecular signals to promote wound repair in renal tubular injury. |
| Q97548396 | Fibrinogen protects neutrophils from the cytotoxic effects of histones and delays neutrophil extracellular trap formation induced by ionomycin |
| Q39426851 | HMGB1 and Extracellular Histones Significantly Contribute to Systemic Inflammation and Multiple Organ Failure in Acute Liver Failure |
| Q39186586 | HMGB1 and Histones Play a Significant Role in Inducing Systemic Inflammation and Multiple Organ Dysfunctions in Severe Acute Pancreatitis. |
| Q42696824 | Heart-kidney crosstalk and role of humoral signaling in critical illness |
| Q35947370 | Heparan Sulfate Modulates Neutrophil and Endothelial Function in Antibacterial Innate Immunity |
| Q40609443 | Hepatic radiofrequency ablation causes an increase of circulating histones in patients with hepatocellular carcinoma. |
| Q92846652 | High levels of cell-free DNA accurately predict late acute kidney injury in patients after cardiac surgery |
| Q93163505 | Histone H2B induces retinal ganglion cell death through toll-like receptor 4 in the vitreous of acute primary angle closure patients |
| Q92576347 | Histone H4 induces platelet ballooning and microparticle release during trauma hemorrhage |
| Q36778660 | Histone cleavage as a mechanism for epigenetic regulation: current insights and perspectives |
| Q37182947 | Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury |
| Q39028315 | Histones and Neutrophil Extracellular Traps Enhance Tubular Necrosis and Remote Organ Injury in Ischemic AKI. |
| Q47733636 | Histones trigger sterile inflammation by activating the NLRP3 inflammasome |
| Q43768628 | Human thrombin-derived host defense peptides inhibit neutrophil recruitment and tissue injury in severe acute pancreatitis |
| Q58699771 | IL-22 sustains epithelial integrity in progressive kidney remodeling and fibrosis |
| Q46122769 | Immune activation by histones: plusses and minuses in inflammation |
| Q38261586 | Immune cells in experimental acute kidney injury |
| Q38176819 | Immunopathology of lupus nephritis |
| Q50324081 | Immunothrombotic Activity of Damage-Associated Molecular Patterns and Extracellular Vesicles in Secondary Organ Failure Induced by Trauma and Sterile Insults. |
| Q34364469 | Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation |
| Q37457064 | Induction of antinuclear antibodies by de novo autoimmune hepatitis regulates alloimmune responses in rat liver transplantation |
| Q41459604 | Infiltration of M1, but not M2, macrophages is impaired after unilateral ureter obstruction in Nrf2-deficient mice |
| Q35889959 | Innate immunity in donor procurement |
| Q43099963 | Innate versus adaptive immunity in kidney immunopathology. |
| Q33420055 | Inter-α inhibitor protein and its associated glycosaminoglycans protect against histone-induced injury |
| Q38192855 | Interaction between systemic inflammation and renal tubular epithelial cells. |
| Q37662678 | Intracellular Hmgb1 inhibits inflammatory nucleosome release and limits acute pancreatitis in mice |
| Q89164285 | Intrarenal Toll-like receptor 4 and Toll-like receptor 2 expression correlates with injury in antineutrophil cytoplasmic antibody-associated vasculitis |
| Q38279420 | Ischemia as a factor affecting innate immune responses in kidney transplantation |
| Q89576485 | LPS-Challenged Macrophages Release Microvesicles Coated With Histones |
| Q38692356 | Links between coagulation, inflammation, regeneration, and fibrosis in kidney pathology. |
| Q42057001 | Local Joint inflammation and histone citrullination in a murine model of the transition from preclinical autoimmunity to inflammatory arthritis |
| Q35688293 | Lung inflammation and damage induced by extracellular histones |
| Q50035169 | Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD. |
| Q37524085 | Macrophage phenotype controls long-term AKI outcomes--kidney regeneration versus atrophy |
| Q35122939 | Maximum efficacy of mesenchymal stem cells in rat model of renal ischemia-reperfusion injury: renal artery administration with optimal numbers |
| Q98177680 | Metabolic Flexibility and Innate Immunity in Renal Ischemia Reperfusion Injury: The Fine Balance Between Adaptive Repair and Tissue Degeneration |
| Q38579499 | Necroinflammation in Kidney Disease |
| Q36104809 | Neutrophil Extracellular Trap-Related Extracellular Histones Cause Vascular Necrosis in Severe GN |
| Q48128888 | Neutrophil Extracellular Traps Are Pathogenic in Ventilator-Induced Lung Injury and Partially Dependent on TLR4. |
| Q27324250 | Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis |
| Q92421763 | Neutrophil Extracellular Traps in the Establishment and Progression of Renal Diseases |
| Q39154403 | Neutrophil dysregulation during sepsis: an overview and update |
| Q37497942 | Neutrophil extracellular trap formation and circulating nucleosomes in patients with chronic myeloproliferative neoplasms |
| Q37641674 | Novel chemokine-like activities of histones in tumor metastasis |
| Q36830358 | Nuclear antigens and auto/alloantibody responses: friend or foe in transplant immunology. |
| Q35118316 | Organ distribution of histones after intravenous infusion of FITC histones or after sepsis |
| Q90989332 | Osteopontin protects against lung injury caused by extracellular histones |
| Q35197441 | PAD4-deficiency does not affect bacteremia in polymicrobial sepsis and ameliorates endotoxemic shock |
| Q26747422 | Paradoxical Roles of the Neutrophil in Sepsis: Protective and Deleterious |
| Q49506021 | Partners in crime: neutrophils and monocytes/macrophages in inflammation and disease. |
| Q26785893 | Pathophysiological role of different tubular epithelial cell death modes in acute kidney injury |
| Q50052115 | Pathophysiology of heatstroke in dogs - revisited. |
| Q38257918 | Pathophysiology of ischaemic acute kidney injury. |
| Q39359763 | Patients with HBV-related acute-on-chronic liver failure have increased concentrations of extracellular histones aggravating cellular damage and systemic inflammation |
| Q38217071 | Pattern recognition receptors and the inflammasome in kidney disease. |
| Q34439789 | Peptidyl arginine deiminase-4 activation exacerbates kidney ischemia-reperfusion injury |
| Q37545034 | Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury. |
| Q41914819 | Perioperative Elevation in Cell-Free DNA Levels in Patients Undergoing Cardiac Surgery: Possible Contribution of Neutrophil Extracellular Traps to Perioperative Renal Dysfunction |
| Q38823721 | Physiological aspects of Toll-like receptor 4 activation in sepsis-induced acute kidney injury |
| Q46048434 | Podocyte loss involves MDM2-driven mitotic catastrophe. |
| Q38788555 | Presence of Cytotoxic Extracellular Histones in Machine Perfusate of Donation After Circulatory Death Kidneys |
| Q37412468 | Protein cross-linking by chlorinated polyamines and transglutamylation stabilizes neutrophil extracellular traps. |
| Q26852032 | Protein-based therapies for acute lung injury: targeting neutrophil extracellular traps |
| Q60912721 | RNA inhibitors of nuclear proteins responsible for multiple organ dysfunction syndrome |
| Q99238602 | Recent Advances in the Role of Natural Killer Cells in Acute Kidney Injury |
| Q48109327 | Recent advances in pathophysiology of disseminated intravascular coagulation: the role of circulating histones and neutrophil extracellular traps |
| Q92874976 | Recombinant human soluble thrombomodulin is associated with attenuation of sepsis-induced renal impairment by inhibition of extracellular histone release |
| Q92643552 | Recombinant thrombomodulin prevents acute lung injury induced by renal ischemia-reperfusion injury |
| Q35679542 | Release and activity of histone in diseases |
| Q35027699 | Retracted: Histones-Mediated Lymphocyte Apoptosis during Sepsis Is Dependent on p38 Phosphorylation and Mitochondrial Permeability Transition |
| Q89142240 | Role of complement C5a and histones in septic cardiomyopathy |
| Q35555107 | Role of extracellular histones in the cardiomyopathy of sepsis. |
| Q27023218 | Role of necroptosis in the pathogenesis of solid organ injury |
| Q92711301 | Roles of Inflammasomes in Inflammatory Kidney Diseases |
| Q49880322 | Selective Biological Responses of Phagocytes and Lungs to Purified Histones. |
| Q27027282 | Sepsis and ARDS: The Dark Side of Histones |
| Q99607604 | Site-specific opening of the blood-brain barrier by extracellular histones |
| Q36776946 | Soluble alpha-enolase activates monocytes by CD14-dependent TLR4 signalling pathway and exhibits a dual function |
| Q90606317 | Systemic and Cardiac Alterations After Long Bone Fracture |
| Q48244517 | The Role of Danger Signals in the Pathogenesis and Perpetuation of Critical Illness |
| Q89731961 | The Role of Extracellular DNA and Histones in Ischaemia-Reperfusion Injury of the Myocardium |
| Q45325237 | The Role of Extracellular Histones in Influenza Virus Pathogenesis |
| Q58780967 | The Role of Toll-Like Receptor 2 and 4 Innate Immunity Pathways in Intracortical Microelectrode-Induced Neuroinflammation |
| Q99712217 | The Yin and Yang of Alarmins in Regulation of Acute Kidney Injury |
| Q38219327 | The complex role of DNA, histones and HMGB1 in the pathogenesis of SLE. |
| Q92300956 | The effect of palmitic acid on inflammatory response in macrophages: an overview of molecular mechanisms |
| Q38137749 | The immune system and kidney disease: basic concepts and clinical implications. |
| Q38679240 | The role of extracellular histone in organ injury |
| Q38803313 | The role of extracellular histones in haematological disorders |
| Q60909251 | The role of extracellular histones in systemic-onset juvenile idiopathic arthritis |
| Q88671029 | The role of platelets in acute kidney injury |
| Q27010599 | The translocation of nuclear molecules during inflammation and cell death |
| Q50776446 | Therapeutic potential of mesenchymal stem cells in acute kidney injury is affected by administration timing. |
| Q30583254 | Therapeutic translation in acute kidney injury: the epithelial/endothelial axis |
| Q38068399 | Tissues use resident dendritic cells and macrophages to maintain homeostasis and to regain homeostasis upon tissue injury: the immunoregulatory role of changing tissue environments. |
| Q37733573 | Toll-like receptor 4-induced IL-22 accelerates kidney regeneration. |
| Q40941653 | Toll-like receptors TLR4 (Asp299Gly and Thr399Ile) and TLR2 (Arg677Trp and Arg753Gln) gene polymorphisms in end-stage renal disease patients on peritoneal dialysis |
| Q39016831 | Toxic effects of extracellular histones and their neutralization by vitreous in retinal detachment |
| Q64900832 | Updated developments on molecular imaging and therapeutic strategies directed against necrosis. |
| Q49989958 | VEGF mitigates histone induced pyroptosis in the remote liver injury associated with renal allograft ischemia-reperfusion injury in rats. |
| Q30275356 | Viperid Envenomation Wound Exudate Contributes to Increased Vascular Permeability via a DAMPs/TLR-4 Mediated Pathway |
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