Neuroprotective effect of the free radical scavenger MCI-186 in patients with cerebral infarction: clinical evaluation using magnetic resonance imaging and spectroscopy

scientific article published on 01 September 1998

Neuroprotective effect of the free radical scavenger MCI-186 in patients with cerebral infarction: clinical evaluation using magnetic resonance imaging and spectroscopy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S1052-3057(98)80049-9
P698PubMed publication ID17895107

P2093author name stringH Abe
K Kamada
N Nakayama
K Houkin
T Kashiwaba
T Noujou
P2860cites workEarly time course of N-acetylaspartate, creatine and phosphocreatine, and compounds containing choline in the brain after acute stroke. A proton magnetic resonance spectroscopy studyQ28317375
Cerebral lactate production and blood flow in acute strokeQ30855931
Cerebral lactate detected by regional proton magnetic resonance spectroscopy in a patient with cerebral infarctionQ36438902
Proton magnetic resonance spectroscopy of cerebral lactate and other metabolites in stroke patientsQ41122327
Increased lipid peroxidation in vulnerable brain regions after transient forebrain ischemia in ratsQ41316336
Strong attenuation of ischemic and postischemic brain edema in rats by a novel free radical scavengerQ41968726
Rebound alkalosis and persistent lactate: multinuclear (1H, 13C, 31P) NMR spectroscopic studies in ratsQ44615849
Effect of MCI-186 on brain edema in ratsQ44710629
Effect of MCI-186 on ischemia-induced changes in monoamine metabolism in rat brainQ46471192
Long-term follow-up of cerebral infarction patients with proton magnetic resonance spectroscopyQ48127386
Localized proton spectroscopy of focal brain pathology in humans: significant effects of edema on spin-spin relaxation timeQ48133268
Combined magnetic resonance imaging and proton magnetic resonance spectroscopy of patients with acute strokeQ48446768
Spectroscopic imaging of stroke in humans: Histopathology correlates of spectral changesQ48458977
Metabolic and neurological patterns in chronic cerebral infarction: a single-voxel 1H-MR spectroscopy studyQ48647749
Delayed neuronal death prevented by inhibition of increased hydroxyl radical formation in a transient cerebral ischemiaQ48658567
Clinical correlates of proton magnetic resonance spectroscopy findings after acute cerebral infarction.Q52351431
Preventive effect of MCI-186 on 15-HPETE induced vascular endothelial cell injury in vitroQ70409918
Early temporal variation of cerebral metabolites after human stroke. A proton magnetic resonance spectroscopy studyQ72628512
Longitudinal changes in proton magnetic resonance spectroscopy in cerebral infarctionQ72905804
P4510describes a project that usesmagnetic resonance imagingQ161238
P433issue5
P921main subjectcerebral infarctionQ1209150
P304page(s)315-322
P577publication date1998-09-01
P1433published inJournal of Stroke and Cerebrovascular DiseasesQ15762579
P1476titleNeuroprotective effect of the free radical scavenger MCI-186 in patients with cerebral infarction: clinical evaluation using magnetic resonance imaging and spectroscopy
P478volume7

Reverse relations

cites work (P2860)
Q37034277Clinical analysis of 207 patients who developed renal disorders during or after treatment with edaravone reported during post-marketing surveillance
Q91982339Edaravone-Loaded Alginate-Based Nanocomposite Hydrogel Accelerated Chronic Wound Healing in Diabetic Mice
Q44088749Effect of the free radical scavenger, 3-methyl-1-phenyl-2-pyrazolin-5-one (MCI-186), on hypoxia-ischemia-induced brain injury in neonatal rats
Q39209409Effects of edaravone on amyloid-β precursor protein processing in SY5Y-APP695 cells
Q44611122Free radical scavenger protects against inner hair cell loss after cochlear ischemia
Q34769939Free radical scavenger, edaravone, reduces the lesion size of lacunar infarction in human brain ischemic stroke
Q47700268How is edaravone effective against acute ischemic stroke and amyotrophic lateral sclerosis?
Q28484248Neurodegenerative evidence in mice brains with cecal ligation and puncture-induced sepsis: preventive effect of the free radical scavenger edaravone
Q53398229Neuroprotective effects of lithium treatment following hypoxic-ischemic brain injury in neonatal rats.
Q80600933Nitric oxide-induced apoptosis in cultured rat astrocytes: protection by edaravone, a radical scavenger
Q44582063Normalization by edaravone, a free radical scavenger, of irradiation-reduced endothelial nitric oxide synthase expression
Q28384392Oxidant Mechanisms in Renal Injury and Disease
Q55296386Pretreatment with the Free Radical Scavenger Edaravone Mitigates Kidney Glycogen Depletion and Neutrophil Infiltration after Leg Ischemia in a Rat Model: A Pilot Study.
Q46118701Survivin is involved in the anti-apoptotic effect of edaravone in PC12 cells

Search more.