Overcoming hypoxic-resistance of tumor cells to TRAIL-induced apoptosis through melatonin

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Overcoming hypoxic-resistance of tumor cells to TRAIL-induced apoptosis through melatonin is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/IJMS150711941
P8608Fatcat IDrelease_awas6imijrafpo2qlkwgj4wa2m
P932PMC publication ID4139822
P698PubMed publication ID25000265
P5875ResearchGate publication ID263744772

P2093author name stringJu-Hee Lee
Ji-Hong Moon
Sang-Youel Park
You-Jin Lee
P2860cites workHypoxia-inducible factor 1 regulated ARC expression mediated hypoxia induced inactivation of the intrinsic death pathway in p53 deficient human colon cancer cells.Q51540826
Hypoxia inhibition of apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).Q52594169
Reactive oxygen species regulate Bax translocation and mitochondrial transmembrane potential, a possible mechanism for enhanced TRAIL-induced apoptosis by CCCP.Q53569131
Hypoxia increases normal prostate epithelial cell resistance to receptor-mediated apoptosis via AKT activationQ83184093
Identification and characterization of a new member of the TNF family that induces apoptosisQ24318423
Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine familyQ24320301
Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: meta-analysisQ24537556
Melatonin and its analogs in insomnia and depressionQ28249175
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensingQ29615506
Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor proteinQ29615931
Hypoxia induces chemoresistance in ovarian cancer cells by activation of signal transducer and activator of transcription 3.Q33945427
Melatonin: from basic research to cancer treatment clinicsQ34637686
Reducing oxidative/nitrosative stress: a newly-discovered genre for melatoninQ34994305
Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activationQ35120687
Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxiaQ35956449
Potential role of tryptophan derivatives in stress responses characterized by the generation of reactive oxygen and nitrogen species.Q37110286
HIF-1: a key mediator in hypoxia.Q37407362
Treatment of kidney cancer: insights provided by the VHL tumor-suppressor proteinQ37463877
Potential roles of melatonin and chronotherapy among the new trends in hypertension treatmentQ37537666
Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic aminesQ37538940
Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosisQ37610475
Circadian rhythm desynchronosis, jet lag, shift lag, and coping strategiesQ37949943
Sensitization of melanoma cells for TRAIL-induced apoptosis by activation of mitochondrial pathways via Bax.Q38173170
Sulforaphane blocks hypoxia-mediated resistance to TRAIL-induced tumor cell deathQ38475327
Hypoxia protects neuronal cells from human prion protein fragment-induced apoptosisQ38491011
Melatonin suppresses tumor progression by reducing angiogenesis stimulated by HIF-1 in a mouse tumor modelQ39290492
Reactive oxygen species and p38 MAPK regulate Bax translocation and calcium redistribution in salubrinal-induced apoptosis of EBV-transformed B cellsQ39447788
Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation.Q39457354
Sphingosine kinase 1 pathway is involved in melatonin-induced HIF-1α inactivation in hypoxic PC-3 prostate cancer cellsQ39578109
Melatonin reduces pancreatic tumor cell viability by altering mitochondrial physiologyQ39625808
Melatonin suppresses tumor angiogenesis by inhibiting HIF-1alpha stabilization under hypoxiaQ39706575
Inhibition of hypoxia-inducible factor-1 function enhances the sensitivity of multiple myeloma cells to melphalanQ39813872
Melatonin down-regulates HIF-1 alpha expression through inhibition of protein translation in prostate cancer cells.Q39833800
Hypoxia inhibits TRAIL-induced tumor cell apoptosis: involvement of lysosomal cathepsinsQ40202626
Enhancing TRAIL-induced apoptosis by Bcl-X(L) siRNA.Q40431817
Hypoxia inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by blocking Bax translocationQ40543909
Ectopic expression of Bcl-2 and Bcl-xL inhibits apoptosis induced by TNF-related apoptosis-inducing ligand (TRAIL) through suppression of caspases-8, 7, and 3 and BID cleavage in human acute myelogenous leukemia cell line HL-60.Q40742709
Adenoviral-mediated transfer of the TNF-related apoptosis-inducing ligand/Apo-2 ligand gene induces tumor cell apoptosisQ40860890
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.Q40975748
Comparative pharmacological studies of melatonin receptors: MT1, MT2 and MT3/QR2. Tissue distribution of MT3/QR2 .Q43593899
Melatonin reduces cardiac inflammatory injury induced by acute exerciseQ45854411
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylationQ46626427
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P921main subjecthypoxiaQ105688
melatoninQ180912
P304page(s)11941-11956
P577publication date2014-07-04
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleOvercoming hypoxic-resistance of tumor cells to TRAIL-induced apoptosis through melatonin
P478volume15

Reverse relations

cites work (P2860)
Q36574369Hypoxia-mediated autophagic flux inhibits silver nanoparticle-triggered apoptosis in human lung cancer cells.
Q41697020Multiwell capillarity-based microfluidic device for the study of 3D tumour tissue-2D endothelium interactions and drug screening in co-culture models
Q42315956RIP-1/c-FLIPL Induce Hepatic Cancer Cell Apoptosis Through Regulating Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)
Q33816685Regulation of transforming growth factor-beta1 (TGF-β1)-induced pro-fibrotic activities by circadian clock gene BMAL1.
Q47282821Thermodynamic Aspects and Reprogramming Cellular Energy Metabolism during the Fibrosis Process

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