Sphingosine kinase 1 pathway is involved in melatonin-induced HIF-1α inactivation in hypoxic PC-3 prostate cancer cells (scientific article published on 11 March 2011)

1,2,3,4,6-Penta-O-galloly-beta-D-glucose suppresses hypoxia-induced accumulation of hypoxia-inducible factor-1α and signaling in LNCaP prostate cancer cells.

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Inhibition of cyclooxygenase-2-dependent survivin mediates decursin-induced apoptosis in human KBM-5 myeloid leukemia cells

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The IGFR1 inhibitor NVP-AEW541 disrupts a pro-survival and pro-angiogenic IGF-STAT3-HIF1 pathway in human glioblastoma cells

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Melatonin suppresses tumor angiogenesis by inhibiting HIF-1alpha stabilization under hypoxia

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Melatonin down-regulates HIF-1 alpha expression through inhibition of protein translation in prostate cancer cells.

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Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: therapeutic implications for prostate cancer

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Sphingosine kinase 1: a new modulator of hypoxia inducible factor 1alpha during hypoxia in human cancer cells.

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Sulforaphane inhibited expression of hypoxia-inducible factor-1alpha in human tongue squamous cancer cells and prostate cancer cells

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Melatonin modulates the expression of VEGF and HIF-1 alpha induced by CoCl2 in cultured cancer cells

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Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor

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Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages

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Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

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Inhibition of HIF-1alpha activity by BP-1 ameliorates adjuvant induced arthritis in rats

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Deletion of the sphingosine kinase-1 gene influences cell fate during hypoxia and glucose deprivation in adult mouse cardiomyocytes.

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Intratumoral hypoxia, radiation resistance, and HIF-1.

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Antioxidative Protection by Melatonin: Multiplicity of Mechanisms from Radical Detoxification to Radical Avoidance

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Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*

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The human side of hypoxia-inducible factor

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Targeting HIF-1 for cancer therapy

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The biology of VEGF and its receptors

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Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

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Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation

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Oxidative stress-dependent sphingosine kinase-1 inhibition mediates monoamine oxidase A-associated cardiac cell apoptosis

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Purification and characterization of hypoxia-inducible factor 1

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Oxygen sensing by HIF hydroxylases

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Sphingosine-1-phosphate: an enigmatic signalling lipid

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Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer

Q34168873

P433

issue

P921

main subject

hypoxia

melatonin

prostate cancer

page(s)

87-93

P577

publication date

2011-03-11

P1433

published in

Journal of Pineal Research

Q15056565

P1476

title

Sphingosine kinase 1 pathway is involved in melatonin-induced HIF-1α inactivation in hypoxic PC-3 prostate cancer cells

P478

volume

Reverse relations

cites work (P2860)

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P356	DOI	10.1111/J.1600-079X.2011.00865.X
P698	PubMed publication ID	21392092