| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/S12640-015-9563-7 |
| P698 | PubMed publication ID | 26472207 |
| P2093 | author name string | Akira Hara | |
| Keiji Tabuchi | |||
| Kohsuke Tani | |||
| P2860 | cites work | Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform | Q22253469 |
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| Role of inhibitor of apoptosis protein in gentamicin-induced cochlear hair cell damage | Q28571821 | ||
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| Sphingosine kinase 1 is overexpressed and promotes proliferation in human thyroid cancer | Q33636769 | ||
| Overexpression of sphingosine kinase 1 is associated with salivary gland carcinoma progression and might be a novel predictive marker for adjuvant therapy | Q33693882 | ||
| Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. | Q33773569 | ||
| SKI-II reverses the chemoresistance of SGC7901/DDP gastric cancer cells | Q33778535 | ||
| Sphingosine kinase 1 regulates the Akt/FOXO3a/Bim pathway and contributes to apoptosis resistance in glioma cells | Q33916859 | ||
| A protocol for cryoembedding the adult guinea pig cochlea for fluorescence immunohistology | Q34112746 | ||
| Overexpression of sphingosine-1-phosphate lyase or inhibition of sphingosine kinase in Dictyostelium discoideum results in a selective increase in sensitivity to platinum-based chemotherapy drugs | Q34360594 | ||
| Involvement of N-terminal-extended form of sphingosine kinase 2 in serum-dependent regulation of cell proliferation and apoptosis | Q34443449 | ||
| Loss of sphingosine kinase-1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin-induced DNA damage | Q34540244 | ||
| Mechanisms of cisplatin-induced ototoxicity and prevention | Q34582682 | ||
| Krebs von den Lungen-6 (KL-6) is a prognostic biomarker in patients with surgically resected nonsmall cell lung cancer | Q34627201 | ||
| Cellular signaling by sphingosine and sphingosine 1-phosphate. Their opposing roles in apoptosis | Q34661457 | ||
| Cancer Treatment Strategies Targeting Sphingolipid Metabolism | Q34790629 | ||
| A phase I clinical trial of safingol in combination with cisplatin in advanced solid tumors | Q34809705 | ||
| Sphingosine-1-phosphate: dual messenger functions | Q34980697 | ||
| Sphingosine kinase, sphingosine-1-phosphate, and apoptosis | Q35047178 | ||
| An increased abundance of tumor-infiltrating regulatory T cells is correlated with the progression and prognosis of pancreatic ductal adenocarcinoma | Q35122843 | ||
| Sphingolipid metabolism, oxidant signaling, and contractile function of skeletal muscle | Q35222194 | ||
| Sphingosine kinase inhibitors and cancer: seeking the golden sword of Hercules | Q35501532 | ||
| Cisplatin ototoxicity in rat cochlear organotypic cultures | Q35592843 | ||
| Sphingosine-1-phosphate signaling and its role in disease | Q35661485 | ||
| Ceramide synthesis and metabolism as a target for cancer therapy. | Q35687927 | ||
| Biologically active sphingolipids in cancer pathogenesis and treatment | Q35852313 | ||
| Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival. | Q36294755 | ||
| Dictyostelium discoideum to human cells: pharmacogenetic studies demonstrate a role for sphingolipids in chemoresistance | Q36364902 | ||
| The sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signaling function | Q36415172 | ||
| Sphingosine kinase: biochemical and cellular regulation and role in disease | Q36439269 | ||
| Sphingolipids: regulators of crosstalk between apoptosis and autophagy | Q36462123 | ||
| Regulation and functional roles of sphingosine kinases | Q36715339 | ||
| Inhibitors of the sphingosine kinase pathway as potential therapeutics. | Q37725028 | ||
| Regulation of sphingosine kinase and sphingolipid signaling. | Q37792598 | ||
| Therapeutic potential of targeting sphingosine kinase 1 in prostate cancer | Q37930972 | ||
| The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: oxidative stress and the seesaw of cell survival and death | Q38011930 | ||
| FTY720 and cisplatin synergistically induce the death of cisplatin-resistant melanoma cells through the downregulation of the PI3K pathway and the decrease in epidermal growth factor receptor expression | Q38967343 | ||
| Sphingosine kinase 1 enhances colon cancer cell proliferation and invasion by upregulating the production of MMP-2/9 and uPA via MAPK pathways | Q39333889 | ||
| Sphingosine kinase 1 pathway is involved in melatonin-induced HIF-1α inactivation in hypoxic PC-3 prostate cancer cells | Q39578109 | ||
| Sphingosine kinase 1 is associated with gastric cancer progression and poor survival of patients | Q39881982 | ||
| Sphingosine-induced apoptosis in rhabdomyosarcoma cell lines is dependent on pre-mitochondrial Bax activation and post-mitochondrial caspases | Q40181636 | ||
| Antitumor activity of sphingosine kinase inhibitors | Q40288624 | ||
| Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting sphingosine kinase-1. | Q40352532 | ||
| Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: roles of sphingosine kinase isoforms in growth of glioblastoma cell lines | Q40384186 | ||
| Sphingosine-1-phosphate lyase regulates sensitivity of human cells to select chemotherapy drugs in a p38-dependent manner. | Q40424171 | ||
| An oncogenic role of sphingosine kinase | Q40837836 | ||
| Sphingosine kinase regulates the sensitivity of Dictyostelium discoideum cells to the anticancer drug cisplatin. | Q40895406 | ||
| Tissue culture of the organ of Corti. | Q40897574 | ||
| The influence of sphingosine-1-phosphate receptor antagonists on gentamicin-induced hair cell loss of the rat cochlea | Q42451981 | ||
| Ceramide/sphingomyelin cycle involvement in gentamicin-induced cochlear hair cell death | Q42458420 | ||
| Estradiol protects the cochlea against gentamicin ototoxicity through inhibition of the JNK pathway | Q42465831 | ||
| The influences of sphingolipid metabolites on gentamicin-induced hair cell loss of the rat cochlea | Q42475746 | ||
| Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis | Q42799996 | ||
| Sphingosine generation, cytochrome c release, and activation of caspase-7 in doxorubicin-induced apoptosis of MCF7 breast adenocarcinoma cells. | Q43583211 | ||
| Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria | Q43775894 | ||
| Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis | Q44572814 | ||
| Protective role of Nrf2 in age-related hearing loss and gentamicin ototoxicity | Q50432655 | ||
| Sphingosine induces apoptosis in hippocampal neurons and astrocytes by activating caspase-3/-9 via a mitochondrial pathway linked to SDK/14-3-3 protein/Bax/cytochrome c. | Q52612337 | ||
| Growth of the inner ear in organ culture | Q69357049 | ||
| Toxicity of the protein kinase C inhibitor safingol administered alone and in combination with chemotherapeutic agents | Q72035556 | ||
| Ceramidases | Q73186708 | ||
| Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells | Q73626228 | ||
| Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes | Q74105987 | ||
| Downregulating sphingosine kinase-1 for cancer therapy | Q81626818 | ||
| P433 | issue | 1 | |
| P304 | page(s) | 35-46 | |
| P577 | publication date | 2016-01-01 | |
| P1433 | published in | Neurotoxicity Research | Q15764278 |
| P1476 | title | Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea. | |
| P478 | volume | 29 |
| Q91791063 | Cisplatin induces calcium ion accumulation and hearing loss by causing functional alterations in calcium channels and exocytosis |
| Q46891118 | Cisplatin-induced metabolome changes in serum: an experimental approach to identify markers for ototoxicity |
| Q41952712 | Loss of Sphingosine Kinase Alters Life History Traits and Locomotor Function in Caenorhabditis elegans |
| Q47669705 | NO and HNO donors, nitrones, and nitroxides: Past, present, and future |
| Q36799651 | Sphingosine 1-phosphate receptor 2 (S1P2) attenuates reactive oxygen species formation and inhibits cell death: implications for otoprotective therapy |
| Q38915115 | Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism |
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