| scholarly article | Q13442814 |
| P2093 | author name string | Nadarajah Vigneswaran | |
| Nagathihalli S Nagaraj | |||
| Wolfgang Zacharias | |||
| P2860 | cites work | Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis | Q24310597 |
| Hypoxia-mediated apoptosis in oral carcinoma cells occurs via two independent pathways | Q24804177 | ||
| Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis | Q28263747 | ||
| Exploiting tumour hypoxia in cancer treatment | Q28264146 | ||
| Apoptosis induced by exposure to a low steady-state concentration of H2O2 is a consequence of lysosomal rupture | Q28365604 | ||
| Hypoxia--a key regulatory factor in tumour growth | Q29547318 | ||
| Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics | Q29620467 | ||
| Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor | Q30481000 | ||
| Unraveling the role of proteases in cancer | Q33838143 | ||
| Caspase-8 in apoptosis: the beginning of "the end"? | Q34143631 | ||
| The potential of TRAIL for cancer chemotherapy | Q34271024 | ||
| Four deaths and a funeral: from caspases to alternative mechanisms. | Q34325335 | ||
| Cell death independent of caspases: a review. | Q34415492 | ||
| Cellular stress response and apoptosis in cancer therapy. | Q34417153 | ||
| Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c | Q34457741 | ||
| Apo2L/TRAIL and its death and decoy receptors | Q34532325 | ||
| The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet. | Q34859478 | ||
| The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions | Q35031256 | ||
| Destination 'lysosome': a target organelle for tumour cell killing? | Q35549436 | ||
| Targeting hypoxia tolerance in cancer | Q35741480 | ||
| Apoptosis signaling in tumor therapy | Q36009173 | ||
| Lysosomes as targets for cancer therapy | Q36099892 | ||
| Lysosomes and endoplasmic reticulum: targets for improved, selective anticancer therapy | Q36213403 | ||
| Lysosomes and lysosomal proteins in cancer cell death (new players of an old struggle). | Q36368016 | ||
| Cathepsin-regulated apoptosis | Q36406709 | ||
| Overexpression of both catalytically active and -inactive cathepsin D by cancer cells enhances apoptosis-dependent chemo-sensitivity | Q36465221 | ||
| Modulation of TRAIL-induced tumor cell apoptosis in a hypoxic environment | Q40350114 | ||
| Lysosomal membrane permeabilization during apoptosis--involvement of Bax? | Q40367737 | ||
| Hypoxia alters cathepsin B / inhibitor profiles in oral carcinoma cell lines | Q40388940 | ||
| Cathepsin B promotes both motility and invasiveness of oral carcinoma cells. | Q40449576 | ||
| Hypoxia inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by blocking Bax translocation | Q40543909 | ||
| Influence of hypoxia on TRAIL-induced apoptosis in tumor cells | Q40594222 | ||
| Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins | Q40622338 | ||
| Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine | Q40623373 | ||
| Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route | Q40843079 | ||
| Exocytosis of active cathepsin B enzyme activity at pH 7.0, inhibition and molecular mass | Q40935441 | ||
| Photo-Oxidative Disruption of Lysosomal Membranes Causes Apoptosis of Cultured Human Fibroblasts | Q41138991 | ||
| Cell, tissue and organ culture as in vitro models to study the biology of squamous cell carcinomas of the head and neck | Q41140197 | ||
| Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine. | Q41915692 | ||
| IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms | Q42820922 | ||
| Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein. | Q43002476 | ||
| Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice | Q43860748 | ||
| Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis | Q44463051 | ||
| Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity | Q44516508 | ||
| Differential susceptibility of metastatic and primary oral cancer cells to TRAIL-induced apoptosis. | Q45178817 | ||
| Cathepsin B mediates TRAIL-induced apoptosis in oral cancer cells | Q49189903 | ||
| Hypoxia inhibition of apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). | Q52594169 | ||
| P433 | issue | 1 | |
| P921 | main subject | hypoxia | Q105688 |
| P304 | page(s) | 125-139 | |
| P577 | publication date | 2007-01-01 | |
| P1433 | published in | Apoptosis | Q15749546 |
| P1476 | title | Hypoxia inhibits TRAIL-induced tumor cell apoptosis: involvement of lysosomal cathepsins | |
| P478 | volume | 12 |
| Q51549085 | A Lysosome-Targeting Fluorescence Off-On Probe for Imaging of Nitroreductase and Hypoxia in Live Cells. |
| Q39181108 | AML1/ETO sensitizes via TRAIL acute myeloid leukemia cells to the pro-apoptotic effects of hypoxia |
| Q40084690 | BRCA1 accumulates in the nucleus in response to hypoxia and TRAIL and enhances TRAIL-induced apoptosis in breast cancer cells |
| Q53513140 | Characterization of antimicrobial activity of the lysosomes isolated from Saccharomyces cerevisiae. |
| Q35951617 | Cigarette smoke condensate increases cathepsin-mediated invasiveness of oral carcinoma cells |
| Q24295128 | Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1 |
| Q36574369 | Hypoxia-mediated autophagic flux inhibits silver nanoparticle-triggered apoptosis in human lung cancer cells. |
| Q54377502 | Increased in vitro lysosomal function in oxidative stress-induced cell lines. |
| Q39317094 | Lipotoxicity-mediated cell dysfunction and death involve lysosomal membrane permeabilization and cathepsin L activity |
| Q37160925 | Lysosomal serine protease CLN2 regulates tumor necrosis factor-alpha-mediated apoptosis in a Bid-dependent manner |
| Q34478831 | Nonesterified cholesterol content of lysosomes modulates susceptibility to oxidant-induced permeabilization |
| Q38615458 | Novel mechanistic insights into ectodomain shedding of EGFR Ligands Amphiregulin and TGF-α: impact on gastrointestinal cancers driven by secondary bile acids. |
| Q34072314 | Overcoming hypoxic-resistance of tumor cells to TRAIL-induced apoptosis through melatonin |
| Q104616946 | Protocol for Probing Regulated Lysosomal Activity and Function in Living Cells |
| Q80883582 | Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice |
| Q33288897 | Repression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but not its receptors during oral cancer progression |
| Q36253834 | Targeted Inhibition of Src Kinase Signaling Attenuates Pancreatic Tumorigenesis |
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