Endoplasmic reticulum stress and cancer

scientific article

Endoplasmic reticulum stress and cancer is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.15430/JCP.2014.19.2.75
P932PMC publication ID4204165
P698PubMed publication ID25337575
P5875ResearchGate publication ID267740441

P2093author name stringHyung-Ryong Kim
Soo-Wan Chae
Raj Kumar Yadav
Han Jung Chae
P2860cites workRegulation of genes for glycolytic enzymes in cultured rat hepatoma cell linesQ44911295
Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activityQ46379013
The human myoepithelial cell exerts antiproliferative effects on breast carcinoma cells characterized by p21WAF1/CIP1 induction, G2/M arrest, and apoptosisQ46561125
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylationQ46626427
Expression and splicing of the unfolded protein response gene XBP-1 are significantly associated with clinical outcome of endocrine-treated breast cancerQ46665995
Celecoxib upregulates endoplasmic reticulum chaperones that inhibit celecoxib-induced apoptosis in human gastric cellsQ46736495
Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development.Q46742618
The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cellsQ47859760
Brefeldin A induces p53-independent apoptosis in primary cultures of human prostatic cancer cells.Q50509909
Expression of glucose-regulated stress protein GRP78 is related to progression of melanoma.Q51753373
AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP.Q53595113
Angiostatin induces and sustains dormancy of human primary tumors in miceQ71101907
Deregulation of glucose transporter 1 and glycolytic gene expression by c-MycQ73819236
Detection of Cytokine- and Chemokine-Expressing Cells at the Single Cell LevelQ79197894
Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligandsQ80591503
Localization of GRP78 to mitochondria under the unfolded protein responseQ82357390
Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein responseQ22000747
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-betaQ22011091
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1Q22011167
The unfolded protein response induces the angiogenic switch in human tumor cells through the PERK/ATF4 pathwayQ24297372
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeatsQ24298956
Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gammaQ24299225
Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alphaQ24320638
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alphaQ24322072
Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational controlQ24522941
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alphaQ24540258
The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small moleculeQ24596804
Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myelomaQ24598483
Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myelomaQ24600346
A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell deathQ24620548
Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonucleaseQ24628936
Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cellsQ24648786
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell SurvivalQ24653078
Advances in the understanding of mechanisms and therapeutic use of bortezomibQ26849940
Endoplasmic reticulum stress in malignancyQ27006434
Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiaeQ27937926
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradationQ28131669
Perk is essential for translational regulation and cell survival during the unfolded protein responseQ28140062
The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquinQ28144606
Targeting the endoplasmic reticulum-stress response as an anticancer strategyQ37616303
Mechanism and components of endoplasmic reticulum-associated degradationQ37634749
Targeting the unfolded protein response, XBP1, and the NLRP3 inflammasome in fibrosis and cancerQ37692466
Progress in the unraveling of the endoplasmic reticulum stress/autophagy pathway and cancer: implications for future therapeutic approachesQ37753175
Unfolded protein response in cancer: the physician's perspectiveQ37846249
Tumor stress inside out: cell-extrinsic effects of the unfolded protein response in tumor cells modulate the immunological landscape of the tumor microenvironmentQ37947561
InterfERing with endoplasmic reticulum stressQ37960224
Glucose regulated protein 78: a critical link between tumor microenvironment and cancer hallmarksQ37994524
Targeting endoplasmic reticulum signaling pathways in cancerQ38017716
Structure, function and regulation of the hsp90 machineryQ38117496
Inducible hsp70 in the regulation of cancer cell survival: analysis of chaperone induction, expression and activityQ38161378
The paradox of the unfolded protein response in cancerQ38162137
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.Q38311676
Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2.Q38318490
Effect on tumor cells of blocking survival response to glucose deprivationQ38337197
Glucose-regulated protein GRP78 is up-regulated in prostate cancer and correlates with recurrence and survival.Q38431247
GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancerQ38436413
Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP78.Q39134058
Cell-surface GRP78 facilitates colorectal cancer cell migration and invasionQ39181711
p58(IPK)-mediated attenuation of the proapoptotic PERK-CHOP pathway allows malignant progression upon low glucose.Q39197344
Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival.Q39256984
Virus-tumor interactome screen reveals ER stress response can reprogram resistant cancers for oncolytic virus-triggered caspase-2 cell death.Q39455351
ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growthQ39470144
Preferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways.Q39622895
Implication of unfolded protein response in resveratrol-induced inhibition of K562 cell proliferationQ39769768
Paraquat activates the IRE1/ASK1/JNK cascade associated with apoptosis in human neuroblastoma SH-SY5Y cellsQ39802567
GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomibQ39807121
IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates.Q39814866
Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomasQ39981994
Aggravated endoplasmic reticulum stress as a basis for enhanced glioblastoma cell killing by bortezomib in combination with celecoxib or its non-coxib analogue, 2,5-dimethyl-celecoxibQ40017297
Heat shock protein inhibition is associated with activation of the unfolded protein response pathway in myeloma plasma cellsQ40128062
GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosisQ40144533
Brefeldin A triggers apoptosis associated with mitochondrial breach and enhances HA14-1- and anti-Fas-mediated cell killing in follicular lymphoma cellsQ40146838
Expression of stress response protein Grp78 is associated with the development of castration-resistant prostate cancerQ40216181
Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cellsQ40339637
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.Q40519913
Endoplasmic reticulum stress stimulates the expression of cyclooxygenase-2 through activation of NF-kappaB and pp38 mitogen-activated protein kinaseQ40524016
ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK).Q40659208
Induction of glucose-regulated protein 78 by chronic hypoxia in human gastric tumor cells through a protein kinase C-epsilon/ERK/AP-1 signaling cascadeQ40766932
Brefeldin A-mediated apoptosis requires the activation of caspases and is inhibited by Bcl-2.Q40992689
Oncogenes in tumor metabolism, tumorigenesis, and apoptosisQ41654945
X box-binding protein 1 regulates angiogenesis in human pancreatic adenocarcinomas.Q41859494
Targeting endoplasmic reticulum protein transport: a novel strategy to kill malignant B cells and overcome fludarabine resistance in CLL.Q42115123
Apoptosis factor EI24/PIG8 is a novel endoplasmic reticulum-localized Bcl-2-binding protein which is associated with suppression of breast cancer invasivenessQ42816754
Novel targets for endoplasmic reticulum stress-induced apoptosis in B-CLL.Q42971332
Differential effect of ritonavir and indinavir on immune response to hepatitis C virus in HIV-1 infected patients.Q42995449
Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilizationQ43966834
Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines.Q44358960
Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosisQ44484550
Proteasome inhibitors disrupt the unfolded protein response in myeloma cellsQ28155919
Translational control is required for the unfolded protein response and in vivo glucose homeostasisQ28204066
High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancersQ28208054
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elementsQ28244853
IGFBP-3 binds GRP78, stimulates autophagy and promotes the survival of breast cancer cells exposed to adverse microenvironmentsQ28270043
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinaseQ28296183
ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cellsQ28307506
Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 geneQ28372162
Regulated translation initiation controls stress-induced gene expression in mammalian cellsQ28506388
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulumQ28509611
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulumQ28512249
Cancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI(3,4,5)P3 productionQ28534981
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein responseQ28589998
XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networksQ28591575
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stressQ29615495
Mediators of endoplasmic reticulum stress-induced apoptosisQ29615496
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensingQ29615506
ER stress triggers apoptosis by activating BH3-only protein BimQ29617730
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunitiesQ29617768
A central role for JNK in obesity and insulin resistanceQ29619778
Chemical Genomics Identifies the Unfolded Protein Response as a Target for Selective Cancer Cell Killing during Glucose DeprivationQ29999509
PERK regulates the proliferation and development of insulin-secreting beta-cell tumors in the endocrine pancreas of miceQ30945763
Brefeldin-A induces apoptosis in human adenoid cystic carcinoma cultured cellsQ33200905
Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activityQ33224552
A phase 2 study of bortezomib in relapsed, refractory myelomaQ33348702
Grp78 promotes the invasion of hepatocellular carcinomaQ33524918
Cancer antineovascular therapy with liposome drug delivery systems targeted to BiP/GRP78.Q33533593
Proteasome inhibitors: a novel class of potent and effective antitumor agents.Q33864458
PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damageQ33977034
Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesisQ34192744
X-box binding protein 1 is essential for the anti-oxidant defense and cell survival in the retinal pigment epitheliumQ34310315
The Unfolded Protein Response, Degradation from Endoplasmic Reticulum and CancerQ34576070
Failure of amino acid homeostasis causes cell death following proteasome inhibition.Q34642317
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.Q34702354
A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasisQ34803685
Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cellsQ34836604
Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and agingQ34966603
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cellsQ34979866
Immunogenic cell death, DAMPs and anticancer therapeutics: an emerging amalgamationQ35000446
Inhibition of established micrometastases by targeted drug delivery via cell surface-associated GRP78.Q35090829
Antitumor activity of SNX-2112, a synthetic heat shock protein-90 inhibitor, in MET-amplified tumor cells with or without resistance to selective MET InhibitionQ35688071
Coupling endoplasmic reticulum stress to the cell-death program: a novel HSP90-independent role for the small chaperone protein p23Q35740994
Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implicationsQ35828762
GRP78 Protein Expression in Ovarian Cancer Patients and Perspectives for a Drug-Targeting ApproachQ35864578
Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targetingQ35964550
The role of the unfolded protein response in tumour development: friend or foe?Q35968425
From acute ER stress to physiological roles of the Unfolded Protein ResponseQ36362397
Bortezomib: proteasome inhibition as an effective anticancer therapyQ36366801
Unfolded protein response to autophagy as a promising druggable target for anticancer therapyQ36403652
Targeting XBP-1 as a novel anti-cancer strategy.Q36544398
Enhanced selenium effect on growth arrest by BiP/GRP78 knockdown in p53-null human prostate cancer cellsQ36713198
The endoplasmic reticulum stress marker CHOP predicts survival in malignant mesothelioma.Q36747341
GRP78 induction in cancer: therapeutic and prognostic implications.Q36794164
Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells.Q36836856
Endoplasmic reticulum stress induces PRNP prion protein gene expression in breast cancerQ36903323
GRP78 is overexpressed in glioblastomas and regulates glioma cell growth and apoptosisQ36926745
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.Q36954378
Integrated endoplasmic reticulum stress responses in cancerQ37002431
Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epitheliumQ37039595
GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapyQ37062090
The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillanceQ37118155
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell deathQ37133168
The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapiesQ37285838
Nitrosative stress-induced s-glutathionylation of protein disulfide isomerase leads to activation of the unfolded protein responseQ37373297
Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cellsQ37388595
In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesiclesQ37394440
Activation and clinical significance of the unfolded protein response in breast cancerQ37424111
Retaspimycin hydrochloride (IPI-504): a novel heat shock protein inhibitor as an anticancer agentQ37566640
P433issue2
P921main subjectendoplasmic reticulumQ79927
P304page(s)75-88
P577publication date2014-06-01
P1433published inJournal of cancer preventionQ26841879
P1476titleEndoplasmic reticulum stress and cancer
P478volume19

Reverse relations

cites work (P2860)
Q388464102-Deoxy-d-Glucose Sensitizes Human Ovarian Cancer Cells to Cisplatin by Increasing ER Stress and Decreasing ATP Stores in Acidic Vesicles.
Q92919443A sensitive and simple targeted proteomics approach to quantify transcription factor and membrane proteins of the unfolded protein response pathway in glioblastoma cells
Q46640751Acid-induced autophagy protects human lung cancer cells from apoptosis by activating ER stress
Q36261323Activation of unfolded protein response protects osteosarcoma cells from cisplatin-induced apoptosis through NF-κB pathway
Q38761256Adenovirus siMDM2 and NDRG2 Gene Therapy Inhibits Cell Proliferation and Induces Apoptosis of Squamous Cell Carcinoma
Q90119514Alantolactone enhances gemcitabine sensitivity of lung cancer cells through the reactive oxygen species-mediated endoplasmic reticulum stress and Akt/GSK3β pathway
Q58800467Anti-Cancer Natural Products and Their Bioactive Compounds Inducing ER Stress-Mediated Apoptosis: A Review
Q26738330Anti-Cancer Properties of the Naturally Occurring Aphrodisiacs: Icariin and Its Derivatives
Q64929541Anti-tumor Efficacy Assessment of the Sigma Receptor Pan Modulator RC-106. A Promising Therapeutic Tool for Pancreatic Cancer.
Q91902213Autophagosome accumulation-mediated ATP energy deprivation induced by penfluridol triggers nonapoptotic cell death of lung cancer via activating unfolded protein response
Q92757487Autophagy manipulation as a strategy for efficient anticancer therapies: possible consequences
Q60922814Bilirubin Attenuates ER Stress-Mediated Inflammation, Escalates Apoptosis and Reduces Proliferation in the LS174T Colonic Epithelial Cell Line
Q41595515Calcitriol exerts an anti-tumor effect in osteosarcoma by inducing the endoplasmic reticulum stress response
Q26778533Cancer Microenvironment and Endoplasmic Reticulum Stress Response
Q38737351Cannabinoid derivatives exert a potent anti-myeloma activity both in vitro and in vivo
Q64113597Chemotherapy Resistance Explained through Endoplasmic Reticulum Stress-Dependent Signaling
Q90523395Combinations of Tyrosine Kinase Inhibitor and ERAD Inhibitor Promote Oxidative Stress-Induced Apoptosis through ATF4 and KLF9 in Medullary Thyroid Cancer
Q92813709Cytoskeletal Proteins in Cancer and Intracellular Stress: A Therapeutic Perspective
Q46603417Deoxyrhapontigenin, a Natural Stilbene Derivative Isolated From Rheum undulatum L. Induces Endoplasmic Reticulum Stress-Mediated Apoptosis in Human Breast Cancer Cells
Q64228174Dicerandrol B: a natural xanthone dimer induces apoptosis in cervical cancer HeLa cells through the endoplasmic reticulum stress and mitochondrial damage
Q26801114Drugging the unfolded protein response in acute leukemias
Q28078536ER Stress-Mediated Signaling: Action Potential and Ca(2+) as Key Players
Q38750181Effect of hypoxia on the expression of genes encoding insulin-like growth factors and some related proteins in U87 glioma cells without IRE1 function
Q90613926Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma
Q57236093Ethyl Acetate Extract of cf. Exerts the Inhibitory Bioactivity on Human Non-Small Cell Lung Cancer Cells through Modulating ER Stress
Q47672242Expression of IGFBP6, IGFBP7, NOV, CYR61, WISP1 and WISP2 genes in U87 glioma cells in glutamine deprivation condition
Q64100174Expression of inositol-requiring enzyme 1β is downregulated in azoxymethane/dextran sulfate sodium-induced mouse colonic tumors
Q91859662GOLPH3: a Golgi phosphatidylinositol(4)phosphate effector that directs vesicle trafficking and drives cancer
Q112305456GRP78 determines glioblastoma sensitivity to UBA1 inhibition-induced UPR signaling and cell death
Q47236958Hexose-6-phosphate dehydrogenase controls cancer cell proliferation and migration through pleiotropic effects on the unfolded-protein response, calcium homeostasis, and redox balance
Q36262976Histidine-rich calcium binding protein promotes growth of hepatocellular carcinoma in vitro and in vivo
Q27022246Hypoxia-independent drivers of melanoma angiogenesis
Q49953037Hypoxic regulation of the expression of cell proliferation related genes in U87 glioma cells upon inhibition of ire1 signaling enzyme
Q52629172IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.
Q89478793Inhibition of endoplasmic-reticulum-stress-mediated autophagy enhances the effectiveness of chemotherapeutics on pancreatic cancer
Q57478301Interferon γ suppresses dentin sialophosphoprotein in oral squamous cell carcinoma cells resulting in antitumor effects, via modulation of the endoplasmic reticulum response
Q57461812Interplay between Endoplasmic Reticular Stress and Survivin in Colonic Epithelial Cells
Q90074418Interplay between Endoplasmic Reticulum (ER) Stress and Autophagy Induces Mutant p53H273 Degradation
Q59129737Knockdown of KIAA1199 attenuates growth and metastasis of hepatocellular carcinoma
Q33909832Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death
Q35866050Melatonin Activates Endoplasmic Reticulum Stress and Apoptosis in Rats with Diethylnitrosamine-Induced Hepatocarcinogenesis
Q37644022Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 downregulation
Q37602836Molecular signal networks and regulating mechanisms of the unfolded protein response
Q64922459Mutant p53 and Cellular Stress Pathways: A Criminal Alliance That Promotes Cancer Progression.
Q39333529Myeloid-derived cells in prostate cancer progression: phenotype and prospective therapies.
Q38766296N-Myristoyltransferase Inhibition Induces ER-Stress, Cell Cycle Arrest, and Apoptosis in Cancer Cells
Q88582817NRF2 and the Hallmarks of Cancer
Q57054615New insights into the cellular temporal response to proteostatic stress
Q47096721Nuclear expression of XBP1s is correlated with breast cancer survival: a retrospective analysis based on tissue microarray
Q50061136Oncogenic RAC1 and NRAS drive resistance to endoplasmic reticulum stress through MEK/ERK signalling.
Q91758182Overexpression of cortistatin alleviates oxygen/glucose-deprivation-induced ER stress and prompts neural stem cell proliferation via SSTR2
Q91932985Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers
Q38700179Penfluridol induces endoplasmic reticulum stress leading to autophagy in pancreatic cancer
Q46518062Pinus radiata bark extract induces caspase-independent apoptosis-like cell death in MCF-7 human breast cancer cells
Q35742552Piperlongumine selectively kills hepatocellular carcinoma cells and preferentially inhibits their invasion via ROS-ER-MAPKs-CHOP.
Q92048491Post-ER Stress Biogenesis of Golgi Is Governed by Giantin
Q47214865Promoter hypermethylation inactivate tumour suppressor FAM134B and is associated with poor prognosis in colorectal cancer
Q47762229Protective effect of sulforaphane against retinal degeneration in the Pde6rd10 mouse model of retinitis pigmentosa
Q47309478RETREG1 (FAM134B): a new player in human diseases: 15 years after the discovery in cancer.
Q37690890Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer
Q55496558Role of TXNDC5 in tumorigenesis of colorectal cancer cells: In vivo and in vitro evidence.
Q52600379Rosmarinic acid and siRNA combined therapy represses Hsp27 (HSPB1) expression and induces apoptosis in human glioma cells.
Q33738889SNIPER(TACC3) induces cytoplasmic vacuolization and sensitizes cancer cells to Bortezomib.
Q90454252Sigma Receptors as Endoplasmic Reticulum Stress "Gatekeepers" and their Modulators as Emerging New Weapons in the Fight Against Cancer
Q46343477Silibinin stimluates apoptosis by inducing generation of ROS and ER stress in human choriocarcinoma cells
Q51537754Silver nanoparticles induce irremediable endoplasmic reticulum stress leading to unfolded protein response dependent apoptosis in breast cancer cells.
Q55289611Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity.
Q64055421Stressed: The Unfolded Protein Response in T Cell Development, Activation, and Function
Q92308593THE IMPACT OF ALCOHOL ON PRO-METASTATIC N-GLYCOSYLATION IN PROSTATE CANCER
Q51742725Tannic Acid Induces Endoplasmic Reticulum Stress-Mediated Apoptosis in Prostate Cancer.
Q92860511Tannic acid inhibits lipid metabolism and induce ROS in prostate cancer cells
Q89965531The Emerging Roles of Endoplasmic Reticulum Stress in Balancing Immunity and Tolerance in Health and Diseases: Mechanisms and Opportunities
Q40970538The effect of bovine rotavirus and its nonstructural protein 4 on ER stress-mediated apoptosis in HeLa and HT-29 cells.
Q64284375The onus of cannabinoids in interrupting the molecular odyssey of breast cancer: A critical perspective on UPR and beyond
Q53401976To Decipher the Mycoplasma hominis Proteins Targeting into the Endoplasmic Reticulum and Their Implications in Prostate Cancer Etiology Using Next-Generation Sequencing Data.
Q47198003Transmembrane BAX Inhibitor Motif-6 (TMBIM6) protects against cisplatin-induced testicular toxicity
Q91393719Transmissible ER stress reconfigures the AML bone marrow compartment
Q54979434UFD1 contributes to MYC-mediated leukemia aggressiveness through suppression of the proapoptotic unfolded protein response.
Q35767501UPR Activation and the Down-Regulation of α-Crystallin in Human High Myopia-Related Cataract Lens Epithelium
Q38893853p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer

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