| scholarly article | Q13442814 |
| P50 | author | Frank Sicheri | Q28037300 |
| David Kriebel | Q28360240 | ||
| P2093 | author name string | Zheng Liu | |
| Ani Der-Sarkissian | |||
| Caryn Stiles | |||
| Colleen Schweitzer | |||
| Dan Durocher | |||
| Danka Vuga | |||
| David Chiovitti | |||
| Duane Brumm | |||
| John B Patterson | |||
| Julie L Lucas | |||
| Kori Volkmann | |||
| Kris Krishnan | |||
| Marella Canny | |||
| Uriel M Malyankar | |||
| Xiaoping Wang | |||
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| P433 | issue | 14 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell biology | Q7141 |
| P304 | page(s) | 12743-55 | |
| P577 | publication date | 2011-04-08 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease | |
| P478 | volume | 286 |
| Q41954954 | 5'-deoxy-5'-hydrazinylguanosine as an initiator of T7 Rna polymerase-catalyzed transcriptions for the preparation of labeling-ready RNAs. |
| Q99593981 | A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency |
| Q34036402 | A small molecule inhibitor of redox-regulated protein translocation into mitochondria |
| Q36053744 | Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma. |
| Q47774233 | Adapting Secretory Proteostasis and Function Through the Unfolded Protein Response |
| Q37512322 | Adaptive and Pathogenic Responses to Stress by Stem Cells during Development |
| Q45970202 | Autophagy and the Unfolded Protein Response Promote Pro-fibrotic Effects of TGFβ1 in Human Lung Fibroblasts. |
| Q64283441 | Binding to an Unusual Inactive Kinase Conformation by Highly Selective Inhibitors of Inositol-Requiring Enzyme 1α Kinase-Endoribonuclease |
| Q24598483 | Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma |
| Q35743424 | Cell-Based High-Throughput Luciferase Reporter Gene Assays for Identifying and Profiling Chemical Modulators of Endoplasmic Reticulum Signaling Protein, IRE1. |
| Q38694019 | Combination of Alcohol and Cigarette Smoke Induces Endoplasmic Reticulum Stress and Cell Death in Pancreatic Acinar Cells |
| Q26825417 | DangER: protein ovERload. Targeting protein degradation to treat myeloma |
| Q34393767 | Dinaciclib (SCH727965) inhibits the unfolded protein response through a CDK1- and 5-dependent mechanism |
| Q37529746 | Discovery, Synthesis, and Evaluation of 2,4-Diaminoquinazolines as a Novel Class of Pancreatic β-Cell-Protective Agents against Endoplasmic Reticulum (ER) Stress. |
| Q50528588 | Driving Cancer Tumorigenesis and Metastasis Through UPR Signaling. |
| Q38261088 | Druggable sensors of the unfolded protein response |
| Q26801114 | Drugging the unfolded protein response in acute leukemias |
| Q47223132 | Dual IRE1 RNase functions dictate glioblastoma development. |
| Q36709748 | ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in mice |
| Q34003896 | ER stress, autophagy, and RNA viruses |
| Q39441238 | Emerging Role of the Unfolded Protein Response in Tumor Immunosurveillance. |
| Q89951520 | Endoplasmic Reticulum Stress Signaling in Cancer Cells |
| Q26799567 | Endoplasmic Reticulum Stress in the Diabetic Kidney, the Good, the Bad and the Ugly |
| Q39011260 | Endoplasmic reticulum proteostasis: a key checkpoint in cancer |
| Q34376123 | Endoplasmic reticulum stress and cancer |
| Q36626672 | Endoplasmic reticulum stress sensing in the unfolded protein response |
| Q57243233 | Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications |
| Q53816612 | Expression of XBP1s in fibroblasts is critical for TiAl6 V4 particle-induced RANKL expression and osteolysis. |
| Q96640255 | High expression of spliced X-Box Binding Protein 1 in lung tumors is associated with cancer aggressiveness and epithelial-to-mesenchymal transition |
| Q39299575 | IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. |
| Q61124479 | IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling |
| Q34756838 | Identification of small molecules that protect pancreatic β cells against endoplasmic reticulum stress-induced cell death |
| Q38159909 | Impact of the UPR on the virulence of the plant fungal pathogen A. brassicicola |
| Q35762999 | Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway. |
| Q38996766 | Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival |
| Q57577429 | Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy |
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| Q50131857 | Interplay between P-Glycoprotein Expression and Resistance to Endoplasmic Reticulum Stressors. |
| Q33577558 | Involvement of autophagy induction in penta-1,2,3,4,6-O-galloyl-β-D-glucose-induced senescence-like growth arrest in human cancer cells |
| Q39126546 | Involvement of unfolded protein response, p53 and Akt in modulation of porcine reproductive and respiratory syndrome virus-mediated JNK activation |
| Q58710836 | Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein |
| Q64069954 | Merits and pitfalls of conventional and covalent docking in identifying new hydroxyl aryl aldehyde like compounds as human IRE1 inhibitors |
| Q39106316 | Modulation of intracellular calcium homeostasis blocks autophagosome formation |
| Q28393599 | Molecular Pathways: Immunosuppressive Roles of IRE1α-XBP1 Signaling in Dendritic Cells of the Tumor Microenvironment |
| Q30404387 | Molecular mechanisms of human IRE1 activation through dimerization and ligand binding |
| Q35093910 | Multiple autophosphorylations significantly enhance the endoribonuclease activity of human inositol requiring enzyme 1α. |
| Q39114297 | Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress. |
| Q99623519 | Pharmacological Targeting of IRE1 in Cancer |
| Q92003537 | Pharmacological targeting of the unfolded protein response for disease intervention |
| Q41583320 | Physiological/pathological ramifications of transcription factors in the unfolded protein response |
| Q37576252 | Probing endoplasmic reticulum dynamics using fluorescence imaging and photobleaching techniques |
| Q27003283 | Protein homeostasis as a therapeutic target for diseases of protein conformation |
| Q35408665 | Proteotoxic crisis, the ubiquitin-proteasome system, and cancer therapy |
| Q38917585 | Quercetin induces endoplasmic reticulum stress to enhance cDDP cytotoxicity in ovarian cancer: involvement of STAT3 signaling. |
| Q91660847 | Radiation induces EIF2AK3/PERK and ERN1/IRE1 mediated pro-survival autophagy |
| Q92534980 | Screening and identification of inhibitors of endoplasmic reticulum stress-induced activation of the IRE1α-XBP1 branch |
| Q38123951 | Selective inhibition of the unfolded protein response: targeting catalytic sites for Schiff base modification |
| Q34104084 | Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells. |
| Q39734806 | Structural and functional analysis of the allosteric inhibition of IRE1α with ATP-competitive ligands |
| Q64102473 | Structure and Molecular Mechanism of ER Stress Signaling by the Unfolded Protein Response Signal Activator IRE1 |
| Q27640568 | Structure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitors |
| Q33654550 | Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity |
| Q64903345 | Targeting ER stress/ER stress response in myopathies. |
| Q37682288 | Targeting IRE1 with small molecules counteracts progression of atherosclerosis |
| Q38017716 | Targeting endoplasmic reticulum signaling pathways in cancer |
| Q38811934 | Targeting endoplasmic reticulum stress in liver disease. |
| Q38074493 | Targeting endoplasmic reticulum stress in metabolic disease |
| Q29615491 | Targeting hypoxia in cancer therapy |
| Q55062312 | Targeting the Endoplasmic Reticulum Unfolded Protein Response to Counteract the Oxidative Stress-Induced Endothelial Dysfunction. |
| Q38489729 | Targeting the IRE1α-XBP1 branch of the unfolded protein response in human diseases |
| Q37229190 | Targeting the metabolic microenvironment of tumors |
| Q38545670 | Targeting the unfolded protein response for disease intervention |
| Q39232751 | Targeting the unfolded protein response in cancer |
| Q38132652 | Targeting the unfolded protein response in disease. |
| Q38104475 | Targeting unfolded protein response signaling pathways to ameliorate protein misfolding diseases |
| Q33652759 | The ER stress transducer IRE1β is required for airway epithelial mucin production |
| Q26776377 | The Role of Organelle Stresses in Diabetes Mellitus and Obesity: Implication for Treatment |
| Q57105740 | The Unfolded Protein Response in Breast Cancer |
| Q38159859 | The fungal UPR: a regulatory hub for virulence traits in the mold pathogen Aspergillus fumigatus. |
| Q34807567 | The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells |
| Q48043703 | The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity |
| Q37436781 | The metabolic syndrome and neuropathy: therapeutic challenges and opportunities |
| Q24596804 | The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule |
| Q38994927 | The rise of proteostasis promoters |
| Q38970037 | The unfolded protein response in glioblastomas: targetable or trouble? |
| Q24293771 | The unfolded protein response: integrating stress signals through the stress sensor IRE1α |
| Q39068202 | Tick-borne encephalitis virus triggers inositol-requiring enzyme 1 (IRE1) and transcription factor 6 (ATF6) pathways of unfolded protein response |
| Q38395499 | Transcriptional regulation of secretory capacity by bZip transcription factors |
| Q28087036 | Tumor progression and the different faces of the PERK kinase |
| Q38065305 | Understanding the molecular biology of myeloma and its therapeutic implications |
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| Q39331724 | Vitiligo-inducing phenols activate the unfolded protein response in melanocytes resulting in upregulation of IL6 and IL8. |
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