scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1016/J.MOLCEL.2009.08.021 |
P8608 | Fatcat ID | release_c53srwrfofd6noktdpkx3myofq |
P932 | PMC publication ID | 3101568 |
P698 | PubMed publication ID | 19748352 |
P5875 | ResearchGate publication ID | 26806583 |
P50 | author | Laurie Glimcher | Q6501587 |
P2093 | author name string | Claudio Hetz | |
P2860 | cites work | Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 |
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease | Q22252318 | ||
Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress | Q24291026 | ||
Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats | Q24298956 | ||
pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response | Q24303865 | ||
BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha | Q24310536 | ||
Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast | Q24314476 | ||
AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response | Q24314664 | ||
USP14 inhibits ER-associated degradation via interaction with IRE1alpha | Q24314979 | ||
Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha | Q24320638 | ||
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha | Q24322072 | ||
Autophagy suppresses tumorigenesis through elimination of p62 | Q24650670 | ||
One step at a time: endoplasmic reticulum-associated degradation | Q24658302 | ||
Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease | Q24805574 | ||
Divergent effects of PERK and IRE1 signaling on cell viability | Q27438124 | ||
Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing | Q27649529 | ||
The unfolded protein response signals through high-order assembly of Ire1 | Q27653139 | ||
Autophagy in the Pathogenesis of Disease | Q27860558 | ||
Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins. | Q27931697 | ||
Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins | Q27932183 | ||
Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum | Q27937991 | ||
Proteasome inhibitors disrupt the unfolded protein response in myeloma cells | Q28155919 | ||
The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi | Q28217040 | ||
Cell death: critical control points | Q28240722 | ||
Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis | Q28258427 | ||
The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas | Q28505821 | ||
Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress | Q28506667 | ||
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1 | Q28507338 | ||
PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation | Q28507769 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum | Q28509611 | ||
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis | Q28588618 | ||
XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks | Q28591575 | ||
BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress | Q28592598 | ||
ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulum | Q37186859 | ||
The endoplasmic reticulum stress response in immunity and autoimmunity | Q37231726 | ||
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells | Q37309146 | ||
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder | Q38350959 | ||
IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. | Q39814866 | ||
Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak | Q39865156 | ||
Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1. | Q39917756 | ||
A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1. | Q41854293 | ||
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress | Q42518206 | ||
Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA. | Q47942024 | ||
Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins | Q50336381 | ||
Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum | Q50336389 | ||
Targeted disruption of ATF4 discloses its essential role in the formation of eye lens fibres. | Q52178375 | ||
X-box binding protein 1 (XBP1) C--116G polymorphisms in bipolar disorders and age of onset | Q80495715 | ||
Translocation of Bim to the endoplasmic reticulum (ER) mediates ER stress signaling for activation of caspase-12 during ER stress-induced apoptosis | Q80795514 | ||
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1 | Q80979487 | ||
Genetics of bipolar disorder | Q81010615 | ||
Central role of the scaffold protein tumor necrosis factor receptor-associated factor 2 in regulating endoplasmic reticulum stress-induced apoptosis | Q81507240 | ||
An essential role in liver development for transcription factor XBP-1 | Q28593777 | ||
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival | Q28593963 | ||
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals | Q28646129 | ||
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response | Q29547299 | ||
The BCL-2 protein family: opposing activities that mediate cell death | Q29547380 | ||
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress | Q29547441 | ||
Autophagy is activated for cell survival after endoplasmic reticulum stress | Q29614485 | ||
IRE1 signaling affects cell fate during the unfolded protein response | Q29615502 | ||
Biological and chemical approaches to diseases of proteostasis deficiency | Q29616633 | ||
ER stress triggers apoptosis by activating BH3-only protein Bim | Q29617730 | ||
Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress | Q30164007 | ||
Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast | Q31031519 | ||
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins | Q33262919 | ||
A genetic screen in Drosophila reveals novel cytoprotective functions of the autophagy-lysosome pathway | Q33475622 | ||
The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis. | Q33777806 | ||
On the mechanism of sensing unfolded protein in the endoplasmic reticulum | Q34230593 | ||
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation | Q34345459 | ||
Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury | Q34479417 | ||
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression | Q34563098 | ||
Bax inhibitor-1 regulates endoplasmic reticulum stress-associated reactive oxygen species and heme oxygenase-1 expression | Q34631694 | ||
Messenger RNA targeting to endoplasmic reticulum stress signalling sites. | Q34903088 | ||
The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response | Q35029280 | ||
BAX Inhibitor-1, an ancient cell death suppressor in animals and plants with prokaryotic relatives | Q35838773 | ||
Regulatory roles of JNK in programmed cell death | Q35842920 | ||
XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. | Q36322684 | ||
Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis. | Q36393034 | ||
Endoplasmic reticulum stress-induced apoptosis and auto-immunity in diabetes | Q36393503 | ||
Functionality of unspliced XBP1 is required to explain evolution of overlapping reading frames | Q36620957 | ||
Bax Inhibitor-1 Is a pH-dependent regulator of Ca2+ channel activity in the endoplasmic reticulum | Q36701864 | ||
ER stress signaling and the BCL-2 family of proteins: from adaptation to irreversible cellular damage | Q36940021 | ||
Integrated endoplasmic reticulum stress responses in cancer | Q37002431 | ||
The daily job of night killers: alternative roles of the BCL-2 family in organelle physiology | Q37031106 | ||
Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy | Q37075287 | ||
Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress | Q37105304 | ||
The stress rheostat: an interplay between the unfolded protein response (UPR) and autophagy in neurodegeneration | Q37160833 | ||
The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cells | Q37181198 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 551-561 | |
P577 | publication date | 2009-09-01 | |
P1433 | published in | Molecular Cell | Q3319468 |
P1476 | title | Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome | |
P478 | volume | 35 |
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Q54560901 | AtIRE1A/AtIRE1B and AGB1 independently control two essential unfolded protein response pathways in Arabidopsis. |
Q29547398 | Autophagy and the Integrated Stress Response |
Q39592117 | BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response. |
Q39378629 | BCL-2 family: integrating stress responses at the ER to control cell demise |
Q36000128 | BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α. |
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Q55397623 | Berberine Attenuates Macrophages Infiltration in Intracranial Aneurysms Potentially Through FAK/Grp78/UPR Axis. |
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Q98564760 | Caveolin-1 suppresses tumor formation through the inhibition of the unfolded protein response |
Q38241810 | Cellular mechanisms of endoplasmic reticulum stress signaling in health and disease. 1. An overview. |
Q52886537 | Characterization of IRE1 ribonuclease-mediated mRNA decay in plants using transient expression analyses in rice protoplasts. |
Q24337539 | Control of autophagic cell death by caspase-10 in multiple myeloma |
Q36738017 | Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s |
Q39390726 | Curcumin ameliorates streptozotocin-induced liver damage through modulation of endoplasmic reticulum stress-mediated apoptosis in diabetic rats |
Q36636078 | Cyclophilin D extramitochondrial signaling controls cell cycle progression and chemokine-directed cell motility. |
Q36747723 | Defects in IRE1 enhance cell death and fail to degrade mRNAs encoding secretory pathway proteins in the Arabidopsis unfolded protein response. |
Q41813833 | Deletion of inositol-requiring enzyme-1α in podocytes disrupts glomerular capillary integrity and autophagy |
Q27321332 | Depletion of the C. elegans NAC engages the unfolded protein response, resulting in increased chaperone expression and apoptosis |
Q34734145 | Dual regulation of cadmium-induced apoptosis by mTORC1 through selective induction of IRE1 branches in unfolded protein response |
Q93155378 | Dual role of Endoplasmic Reticulum Stress-Mediated Unfolded Protein Response Signaling Pathway in Carcinogenesis |
Q90441976 | Dysregulation of the unfolded protein response (UPR) in the dorsolateral prefrontal cortex in elderly patients with schizophrenia |
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Q93377121 | ER Stress, CREB, and Memory: A Tangled Emerging Link in Disease |
Q36986979 | ER stress and the decline and fall of pancreatic beta cells in type 1 diabetes |
Q37719188 | ER stress and the unfolded protein response in intestinal inflammation. |
Q88869497 | ER stress and unfolded protein response in ocular health and disease |
Q55025783 | ER stress sensing mechanism: Putting off the brake on UPR transducers. |
Q39445601 | ER stress sensitizes cells to TRAIL through down-regulation of FLIP and Mcl-1 and PERK-dependent up-regulation of TRAIL-R2. |
Q57027930 | ER stress signalling has an activating transcription factor 6α (ATF6)-dependent 'off-switch' |
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Q45874593 | Emerging roles of ER stress in the etiology and pathogenesis of Alzheimer's disease |
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Q38319254 | Endoplasmic reticulum stress and C/EBP homologous protein-induced Bax translocation are involved in angiotensin II-induced apoptosis in cultured neonatal rat cardiomyocytes |
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Q37056146 | Hsp90 regulation of mitochondrial protein folding: from organelle integrity to cellular homeostasis |
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