Abstract is: Laurie Hollis Glimcher (born 1951) is an American physician-scientist who was appointed president and CEO of Dana-Farber Cancer Institute in October 2016. She was elected a Member of the American Philosophical Society in 2019.
| human | Q5 |
| P646 | Freebase ID | /m/0h55ly3 |
| P269 | IdRef ID | 079931154 |
| P213 | ISNI | 0000000046728380 |
| 0000000434931081 | ||
| P244 | Library of Congress authority ID | n2001130479 |
| P3388 | LittleSis people ID | 2778 |
| P5380 | National Academy of Sciences member ID | 3004880 |
| P1006 | Nationale Thesaurus voor Auteursnamen ID | 267760558 |
| P1263 | NNDB people ID | 326/000124951 |
| P496 | ORCID iD | 0000-0002-4971-0404 |
| 0000-0001-9537-3456 | ||
| P214 | VIAF ID | 210082983 |
| P10832 | WorldCat Entities ID | E39PBJdx7k4hhm4kKhwCKgfjG3 |
| P2002 | X username | LGlimcherMD |
| P6424 | affiliation string | Dana-Farber Cancer Institute | |
| P166 | award received | FASEB Excellence in Science Award | Q5424476 |
| L'Oréal-UNESCO Award For Women in Science | Q1786381 | ||
| Stanley J. Korsmeyer Award | Q2331722 | ||
| Fellow of the American Academy of Arts and Sciences | Q52382875 | ||
| American Association of Immunologists Lifetime Achievement Award | Q56667085 | ||
| Marion Spencer Fay Award | Q65952921 | ||
| Vanderbilt Prize in Biomedical Science | Q100377523 | ||
| George M. Kober Medal | Q120717812 | ||
| P27 | country of citizenship | United States of America | Q30 |
| P69 | educated at | Harvard Medical School | Q49121 |
| Radcliffe College | Q49124 | ||
| P108 | employer | Harvard University | Q13371 |
| Cornell University | Q49115 | ||
| Harvard Medical School | Q49121 | ||
| Massachusetts General Hospital | Q126412 | ||
| NewYork–Presbyterian Hospital | Q975653 | ||
| Harvard T.H. Chan School of Public Health | Q5676556 | ||
| Brigham and Women's Hospital | Q2900977 | ||
| Weill Cornell Medicine | Q3567094 | ||
| P734 | family name | Glimcher | Q5569623 |
| Glimcher | Q5569623 | ||
| Glimcher | Q5569623 | ||
| P735 | given name | Laurie | Q1574910 |
| Laurie | Q1574910 | ||
| P463 | member of | American Academy of Arts and Sciences | Q463303 |
| National Academy of Sciences | Q270794 | ||
| P106 | occupation | researcher | Q1650915 |
| immunologist | Q12119633 | ||
| physician-scientist | Q25141651 | ||
| P1344 | participant in | World Economic Forum Annual Meeting 2018 | Q114717234 |
| P551 | residence | United States of America | Q30 |
| P21 | sex or gender | female | Q6581072 |
| P8687 | social media followers | 3373 |
| Q72743259 | 1,25-Dihydroxyvitamin D3 inhibits antigen-induced T cell activation |
| Q44570278 | A DNA binding protein regulated by IL-4 and by differentiation in B cells |
| Q70280666 | A biochemical analysis of Ak molecules from mutant antigen presenting cell lines |
| Q24634609 | A cDNA for a human cyclic AMP response element-binding protein which is distinct from CREB and expressed preferentially in brain |
| Q36365928 | A cell type-specific enhancer in the human B7.1 gene regulated by NF-kappaB |
| Q37628403 | A common factor regulates both Th1- and Th2-specific cytokine gene expression |
| Q38357000 | A dominant mutation within the DNA-binding domain of the bZIP transcription factor Maf causes murine cataract and results in selective alteration in DNA binding |
| Q69083384 | A functional role for signal transduction via the cytoplasmic domains of MHC class II proteins |
| Q36758375 | A lipopolysaccharide-induced DNA-binding protein for a class II gene in B cells is distinct from NF-kappa B. |
| Q39454899 | A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo |
| Q28216172 | A mammalian homolog of Drosophila schnurri, KRC, regulates TNF receptor-driven responses and interacts with TRAF2 |
| Q78045659 | A minimal level of MHC class II expression is sufficient to abrogate autoreactivity |
| Q36974721 | A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells |
| Q28119099 | A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter |
| Q28513976 | A novel group of phospholipase A2s preferentially expressed in type 2 helper T cells |
| Q37019598 | A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy |
| Q22253874 | A novel transcription factor, T-bet, directs Th1 lineage commitment |
| Q33595802 | A potential role for the nuclear factor of activated T cells family of transcriptional regulatory proteins in adipogenesis |
| Q50991697 | A role for the immunological synapse in lineage commitment of CD4 lymphocytes. |
| Q34597920 | A single base mutation in an I-A alpha-chain gene alters T-cell recognition |
| Q33567429 | A tissue-specific DNase I-hypersensitive site in a class II A alpha gene is under trans-regulatory control |
| Q72149254 | Absence of MHC class II molecules reduces CNS demyelination, microglial/macrophage infiltration, and twitching in murine globoid cell leukodystrophy |
| Q51012054 | Absence of the T-bet gene coding for the Th1-related transcription factor does not affect diabetes-associated phenotypes in Balb/c mice. |
| Q28506838 | Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development |
| Q41417898 | Activation of T cells by superantigen in class II-negative mice. |
| Q35640633 | Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice |
| Q46478933 | Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome?like skeletal defects induced by Pdk1 or Cbp mutations in mice |
| Q38048962 | After GWAS: mice to the rescue? |
| Q68994161 | Alteration of a non-polymorphic residue in a class II E beta gene eliminates an antibody-defined epitope without affecting T cell recognition |
| Q39214373 | Amelioration of neurodegenerative diseases by cell death-induced cytoplasmic delivery of humanin. |
| Q24338182 | An HLA-DR? promoter DNA-binding protein is expressed ubiquitously and maps to human chromosomes 22 and 5 |
| Q64915984 | An Ia-positive mouse T-cell clone is functional in presenting antigen to other T cells. |
| Q67490020 | An MHC interaction site maps to the amino-terminal half of the T cell receptor α chain variable domain |
| Q28593777 | An essential role in liver development for transcription factor XBP-1 |
| Q36778895 | An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease |
| Q47839224 | An innate cell-mediated, murine ulcerative colitis-like syndrome in the absence of nuclear factor of activated T cells |
| Q40645803 | An intronic 10-base-pair deletion in a class II A beta gene affects RNA processing |
| Q36377316 | An isotype-specific activator of major histocompatibility complex (MHC) class II genes that is independent of class II transactivator |
| Q41813262 | Analysis of responder cell-cell interactions in the syngeneic mixed leukocyte response |
| Q69949036 | Antigen presentation abrogated in cells expressing truncated Ia molecules |
| Q34792001 | Antigen-driven effector CD8 T cell function regulated by T-bet |
| Q45029165 | Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes |
| Q51990687 | Asthmatic changes in mice lacking T-bet are mediated by IL-13. |
| Q102054099 | Author Correction: XBP-1 and the unfolded protein response (UPR) |
| Q36362059 | Autoimmune diabetes can be induced in transgenic major histocompatibility complex class II-deficient mice |
| Q70560322 | B lymphocyte development and activation independent of MHC class II expression |
| Q71616339 | B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of V beta 5+ thymocytes |
| Q42675165 | B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy |
| Q56908812 | B7-2 (CD86) is essential for the development of IL-4-producing T cells |
| Q24310536 | BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha |
| Q40524301 | BanI polymorphism at the XBP1 locus |
| Q72628282 | Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points |
| Q34241570 | Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes |
| Q45099136 | Binding of toxic shock syndrome toxin-1 to murine major histocompatibility complex class II molecules |
| Q69871273 | Biochemical characterization of I-Ak proteins from mutant antigen-presenting B-cell--B-lymphoma hybridomas |
| Q71825823 | Blockade of CD86 ameliorates Leishmania major infection by down-regulating the Th2 response |
| Q36350610 | Both L3T4+ and Lyt-2+ helper T cells initiate cytotoxic T lymphocyte responses against allogenic major histocompatibility antigens but not against trinitrophenyl-modified self |
| Q43052982 | Breaking down barriers to clinical translation: an interview with Laurie Glimcher. Interview by Sarah Allan |
| Q73302937 | CD8+ effector cells responding to residual class I antigens, with help from CD4+ cells stimulated indirectly, cause rejection of "major histocompatibility complex-deficient" skin grafts |
| Q41110361 | CIITA-dependent and -independent class II MHC expression revealed by a dominant negative mutant |
| Q33839890 | Calcineurin regulates innate antifungal immunity in neutrophils |
| Q46282201 | Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization |
| Q33778151 | Casein expression in cytotoxic T lymphocytes |
| Q35619339 | Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1. |
| Q28271799 | Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice |
| Q38937098 | Class II major histocompatibility complex-deficient mice initially control an infection with Leishmania major but succumb to the disease |
| Q36199291 | Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient mice |
| Q34426104 | Cloning of an interleukin-4 inducible gene from cytotoxic T lymphocytes and its identification as a lipase |
| Q37339787 | Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells |
| Q24680733 | Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system |
| Q70101670 | Complex regulation of class II gene expression: analysis with class II mutant cell lines |
| Q36370334 | Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules |
| Q35745238 | Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus |
| Q37273309 | Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse |
| Q35991486 | Control of bone resorption in mice by Schnurri-3. |
| Q37512184 | Control of immunoglobulin heavy chain constant region gene expression |
| Q34726124 | Control of postnatal bone mass by the zinc finger adapter protein Schnurri-3. |
| Q37928668 | Control of transcription at the murine A alpha locus |
| Q38295828 | Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene |
| Q68092515 | Corticosteroid induction of Ig+Ia- B cells in vitro is mediated via interaction with the glucocorticoid cytoplasmic receptor |
| Q28511459 | Critical roles for transcription factor GATA-3 in thymocyte development |
| Q37379915 | Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites |
| Q62801448 | Cutting Edge: STAT1 and T-bet Play Distinct Roles in Determining Outcome of Visceral Leishmaniasis Caused by Leishmania donovani |
| Q33586045 | Cytoplasmic domain affects membrane expression and function of an Ia molecule |
| Q54446437 | DNA-mediated transfer of major histocompatibility class II I-Ab and I-Abm12 genes into B lymphoma cells: molecular and functional analysis of introduced antigens. |
| Q34802728 | Dampening of death pathways by schnurri-2 is essential for T-cell development |
| Q31830577 | Decreased immediate inflammatory gene induction in activating transcription factor-2 mutant mice |
| Q74171908 | Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc |
| Q74111686 | Delayed rejection of soluble tumor necrosis factor receptor-secreting tumor allografts |
| Q36229692 | Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue. |
| Q52481758 | Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice. |
| Q77476285 | Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet |
| Q41549125 | Developmental and cytokine-mediated regulation of MHC class II gene promoter occupancy in vivo |
| Q38345389 | Differences in DNA sequence specificity among MHC class II X box binding proteins |
| Q41087457 | Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells. |
| Q95811146 | Differential expression of T-bet, a T-box transcription factor required for Th1 T-cell development, in peripheral T-cell lymphomas |
| Q43717848 | Differential induction of class II gene expression in murine pre-B-cell lines by B-cell stimulatory factor-1 and by antibodies to B-cell surface antigens |
| Q42475029 | Differing regulation and function of ICAM-1 and class II antigens on renal tubular cells |
| Q36350993 | Direct evidence that a class II molecule and a simple globular protein generate multiple determinants |
| Q35709954 | Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice |
| Q34073854 | Distal regions of the human IFNG locus direct cell type-specific expression |
| Q70406913 | Distinct cloned class II MHC DNA binding proteins recognize the X box transcription element |
| Q40757721 | Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells |
| Q68192526 | Dominant negative mutants of transcription factor mXBP (CRE-BP1, ATF-2) |
| Q35008217 | Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion |
| Q28389316 | ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis |
| Q72515430 | Early murine Lyme carditis has a macrophage predominance and is independent of major histocompatibility complex class II-CD4+ T cell interactions |
| Q58316590 | Editorial overview |
| Q70281142 | Ek beta mutant antigen-presenting cell lines expressing altered Ak alpha molecules |
| Q38286013 | Endoplasmic reticulum stress in immunity |
| Q28575190 | Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes |
| Q35816089 | Enhanced MHC class II expression in renal proximal tubules precedes loss of renal function in MRL/lpr mice with lupus nephritis |
| Q34187114 | Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis |
| Q70582758 | Evidence that a "four-cell cluster" may prime cytotoxic T-cells during graft rejection |
| Q43510230 | Evidence that autoreactive T hybridomas recognize multiple epitopes on the I-Ak molecule |
| Q35784042 | Excess of rare variants in non-genome-wide association study candidate genes in patients with hypertriglyceridemia |
| Q45194717 | Expression of T-bet by CD4 T cells is essential for resistance to Salmonella infection. |
| Q72120242 | Expression of metalloproteinases in pigmented villonodular synovitis |
| Q35016380 | Expression of the T-cell-specific gamma gene is unnecessary in T cells recognizing class II MHC determinants |
| Q38625919 | Extensive pancreas regeneration following acinar-specific disruption of Xbp1 in mice |
| Q72717995 | Fine specificity of cloned insulin-specific T cell hybridomas: evidence supporting a role for tertiary conformation |
| Q37596032 | Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome |
| Q37596560 | From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis |
| Q53562875 | Functional Activity of a Transformed Thymic Epithelial Cell Line |
| Q37320132 | Functional Th1 cells are required for surgical adhesion formation in a murine model |
| Q41728402 | Functional and molecular characterization of I-A kappa beta mutants is consistent with the predicted three dimensional structure of class II MHC molecules |
| Q70464379 | Functional expression of a cloned I-A beta k gene in B-lymphoma cells |
| Q41716635 | Genes that regulate interleukin-4 expression in T cells |
| Q36365805 | Genetic evidence for a new type of major histocompatibility complex class II combined immunodeficiency characterized by a dyscoordinate regulation of HLA-D alpha and beta chains |
| Q34569614 | Gout: new insights into an old disease. |
| Q24644323 | HCO3-/Cl- anion exchanger SLC4A2 is required for proper osteoclast differentiation and function |
| Q43448540 | Harvard's women four years later |
| Q24613509 | Homeostasis and inflammation in the intestine |
| Q80475591 | How we can help the next generation of scientists: introducing The "Hands-On" Primary Caregiver's Support Program |
| Q41348449 | Human MHC class II gene transcription directed by the carboxyl terminus of CIITA, one of the defective genes in type II MHC combined immune deficiency |
| Q104139732 | Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria |
| Q24318380 | Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fos |
| Q40458981 | Human cytomegalovirus protein US11 provokes an unfolded protein response that may facilitate the degradation of class I major histocompatibility complex products |
| Q38359933 | Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice |
| Q44080556 | I region-restricted antigen presentation by B cell–B lymphoma hybridomas |
| Q44432756 | IA mutant functional antigen-presenting cell lines |
| Q36403717 | IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508. |
| Q35785525 | IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection |
| Q33693895 | IL-23 receptor regulates unconventional IL-17-producing T cells that control bacterial infections |
| Q35760821 | IRE1α activation protects mice against acetaminophen-induced hepatotoxicity |
| Q57285558 | IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity |
| Q92001649 | IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain |
| Q36346159 | Ia antigen-bearing B cell tumor lines can present protein antigen and alloantigen in a major histocompatibility complex-restricted fashion to antigen-reactive T cells |
| Q36335105 | Identification of a cell-surface antigen selectively expressed on the natural killer cell |
| Q38332521 | Identification of a conserved lipopolysaccharide-plus-interleukin-4-responsive element located at the promoter of germ line epsilon transcripts |
| Q36510777 | Identification of an IL-4-inducible gene expressed in differentiating lymphocytes and male germ cells |
| Q40947031 | Identification of c-myc promoter-binding protein and X-box binding protein 1 as interleukin-6 target genes in human multiple myeloma cells |
| Q35588838 | Identification of functional regions on the I-Ab molecule by site-directed mutagenesis |
| Q40444903 | Immune responses in MHC class II-deficient mice |
| Q39528344 | Immunogenetic Analysis of "Natural Killer" Activity in the Mouse |
| Q40903650 | Immunoregulatory effects of superantigens: interactions of staphylococcal enterotoxins with host MHC and non-MHC products |
| Q68259337 | In situ hybridization studies of stromelysin and collagenase messenger RNA expression in rheumatoid synovium |
| Q52224944 | In situ hybridization studies suggest a role for the basic region‐leucine zipper protein hXBP‐1 in exocrine gland and skeletal development during mouse embryogenesis |
| Q41684610 | In vivo footprinting of MHC class II genes: bare promoters in the bare lymphocyte syndrome |
| Q63761595 | Increased bone mass and bone matrix mineralization in schnurri-3 null mice |
| Q63761596 | Increased bone matrix mineralization in Schnurri-3 null mice |
| Q44354846 | Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production |
| Q36362829 | Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo |
| Q69955420 | Influence of accessory cell and T cell surface antigens on mitogen-induced IL 2 receptor expression |
| Q41498068 | Inhibition of IFN-gamma induction of class II MHC genes by cAMP and prostaglandins |
| Q54113549 | Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development. |
| Q35811182 | Intercellular adhesion molecule-1 (ICAM-1) expression is upregulated in autoimmune murine lupus nephritis |
| Q37681652 | Interferon gamma regulates binding of two nuclear protein complexes in a macrophage cell line |
| Q24674526 | Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression |
| Q34985745 | Intersection of the unfolded protein response and hepatic lipid metabolism |
| Q35952040 | Interspecies comparison of human and murine scleroderma reveals IL-13 and CCL2 as disease subset-specific targets |
| Q34430378 | Intrinsic susceptibility of mouse trophoblasts to natural killer cell-mediated attack in vivo |
| Q79175253 | It's a Good Year for Blimp-1 (and Plasma Cells) |
| Q42834256 | Laurie Glimcher: merging cell biology and immune function. Interview by Sedwick Caitlin |
| Q42813351 | Lentivirus delivery of shRNA constructs into osteoblasts |
| Q34415667 | Lineage commitment in lymphocytes: controlling the immune response |
| Q33970744 | Lineage commitment in the immune system: the T helper lymphocyte grows up. |
| Q36403957 | Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis |
| Q36351278 | Loss of a DNA-protein complex correlates with extinguished major histocompatibility complex class II expression in a human B cell |
| Q36659117 | MEKK2 mediates an alternative β-catenin pathway that promotes bone formation |
| Q38147109 | MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cells |
| Q35484970 | MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice |
| Q37690264 | Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules |
| Q45089672 | Maintenance of mouse trophoblast stem cell proliferation by TGF-beta/activin |
| Q36364365 | Major histocompatibility complex class II+B7-1+ tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice |
| Q74589613 | Marking IL-4-producing cells by knock-in of the IL-4 gene |
| Q36271130 | Mice lacking major histocompatibility complex class I and class II molecules |
| Q38110913 | Mitogen-activated protein kinase pathways in osteoblasts |
| Q28393599 | Molecular Pathways: Immunosuppressive Roles of IRE1α-XBP1 Signaling in Dendritic Cells of the Tumor Microenvironment |
| Q40518212 | Molecular cloning of mouse cathepsin D. |
| Q35034059 | Molecular mechanisms regulating Th1 immune responses |
| Q70504017 | Most gamma delta T cells develop normally in the absence of MHC class II molecules |
| Q77863567 | Mouse ATF-2 null mutants display features of a severe type of meconium aspiration syndrome |
| Q68749288 | Murine class II (Ia) molecules associate with human invariant chain |
| Q36345860 | Murine syngeneic mixed lymphocyte response. I. Target antigens are self Ia molecules |
| Q38262607 | Mutations of class II MHC molecules |
| Q28487461 | Mycobacterium tuberculosis Rv2224c modulates innate immune responses |
| Q28298319 | NF-AT-Driven interleukin-4 transcription potentiated by NIP45 |
| Q37377454 | NFATc1 and NFATc2 repress spontaneous osteoarthritis |
| Q73406639 | NFATc1 and NFATc2 together control both T and B cell activation and differentiation |
| Q28511548 | NFATc1 balances quiescence and proliferation of skin stem cells |
| Q37641875 | NFATc1 in inflammatory and musculoskeletal conditions |
| Q30157499 | NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism |
| Q45304863 | NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naïve T(H)cells |
| Q33734456 | NIP45 controls the magnitude of the type 2 T helper cell response. |
| Q33835084 | Nod/Ripk2 signaling in dendritic cells activates IL-17A-secreting innate lymphoid cells and drives colitis in T-bet-/-.Rag2-/- (TRUC) mice. |
| Q44737447 | Non-consensus DNA sequences function in a cell-type-specific enhancer of the mouse class II MHC gene A alpha |
| Q38289894 | Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation |
| Q42408055 | Novel roles for XBP1 in hematopoietic development |
| Q24605866 | Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer |
| Q35572441 | Osteoimmunology at the nexus of arthritis, osteoporosis, cancer, and infection |
| Q37050067 | Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. |
| Q35233081 | Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune system |
| Q72772774 | Peripheral lymphoid development and function in TCR mutant mice |
| Q36404114 | Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice |
| Q47728515 | Pillars article: A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 2000. 100: 655-669. |
| Q28507338 | Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1 |
| Q24291453 | Plasma cell differentiation requires the transcription factor XBP-1 |
| Q68856871 | Polyclonal B-cell activation by a B-cell differentiation factor B151-TRF2. IV. B151-TRF2-responsive F1 B cells consist of two separate populations capable of recognizing only one of the parental I-A products expressed on B cells |
| Q40182044 | Post-translational control of T cell development by the ESCRT protein CHMP5. |
| Q36362973 | Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice |
| Q24322072 | Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha |
| Q36346818 | Production of autoreactive I region-restricted T cell hybridomas |
| Q40871745 | Promoter accessibility within the environment of the MHC is affected in class II-deficient combined immunodeficiency. |
| Q69857404 | Prostaglandin E2 inhibits the activation of cloned T cell hybridomas |
| Q28155919 | Proteasome inhibitors disrupt the unfolded protein response in myeloma cells |
| Q36363812 | Protective role of major histocompatibility complex class II Ebd transgene on collagen-induced arthritis |
| Q80841800 | Protective role of nuclear factor of activated T cells 2 in CD8+ long-lived memory T cells in an allergy model |
| Q37834769 | Protein folding stress in neurodegenerative diseases: a glimpse into the ER. |
| Q42119024 | Protein homeostasis networks in physiology and disease |
| Q37154230 | RETRACTED: The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling |
| Q28589998 | Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response |
| Q35934180 | Recent developments in the transcriptional regulation of cytolytic effector cells |
| Q42566461 | Reflections on health care |
| Q37764410 | Regulation of MHC class II gene transcription |
| Q40801142 | Regulation of Memory Formation by the Transcription Factor XBP1. |
| Q36362480 | Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules |
| Q40275083 | Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3. |
| Q37641879 | Regulation of bone formation and immune cell development by Schnurri proteins |
| Q39748822 | Regulation of class II gene expression in a murine pre-B cell line. |
| Q70309586 | Regulation of class II gene expression: analysis in B cell stimulatory factor 1-inducible murine pre-B cell lines |
| Q41497906 | Regulation of cytokine gene expression in T helper cell subsets. |
| Q28507784 | Regulation of hepatic lipogenesis by the transcription factor XBP1 |
| Q34590456 | Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum |
| Q41232989 | Regulation of the E beta gene in vivo: lessons from E beta d transgenic mice |
| Q71059429 | Rejection of MHC class II-transfected tumor cells requires induction of tumor-encoded B7-1 and/or B7-2 costimulatory molecules |
| Q64891319 | Renal tubular cell expression of MHC class II (I-Eb) is insufficient to initiate immune injury in a transgenic kidney transplant model. |
| Q77660701 | Repression of Constitutive and Interferon-gamma-Induced Class II Major Histocompatibility Complex Genes by Cyclic AMP and Prostaglandins |
| Q41655847 | Repression of class II major histocompatibility complex genes by cyclic AMP is mediated by conserved promoter elements |
| Q30657962 | Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development |
| Q53521686 | Restoration of T-box-containing protein expressed in T cells protects against allergen-induced asthma. |
| Q55129749 | Retraction Notice to: The Unfolded Protein Response Element IRE1α Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling. |
| Q38333022 | Role of lipopolysaccharide and IL-4 in control of transcription of the class II A alpha gene |
| Q37660607 | SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts |
| Q24676215 | Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells |
| Q36969891 | Schnurri-3 is an essential regulator of osteoblast function and adult bone mass |
| Q37123939 | Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts |
| Q56565531 | Schnurri-3: A Key Regulator of Postnatal Skeletal Remodeling |
| Q54000307 | Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo. |
| Q36135151 | Sequences and factors: a guide to MHC class-II transcription |
| Q28507094 | Sequential involvement of NFAT and Egr transcription factors in FasL regulation |
| Q36348224 | Serologic and functional characterization of a panel of antigen-presenting cell lines expressing mutant I-A class II molecules |
| Q34879911 | Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus |
| Q35951832 | Signaling pathways in Th2 development |
| Q41593984 | Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression |
| Q36330343 | Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice. |
| Q74460194 | Single amino acid mutations in the murine MHC class II A beta cytoplasmic domain abrogate antigen presentation |
| Q72233696 | Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice |
| Q68046290 | Stimulated kidney tubular epithelial cells express membrane associated and secreted TNF alpha |
| Q36354553 | Structural mutation affecting intracellular transport and cell surface expression of murine class II molecules |
| Q43585133 | Structure and function of murine class II major histocompatibility complex genes. |
| Q28260653 | Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities |
| Q56607614 | Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities☆ |
| Q36344437 | T cell abnormalities in NZB mice occur independently of autoantibody production |
| Q46393789 | T cell clones and hybridomas as probes for the analysis of the syngeneic mixed leukocyte reaction |
| Q35685186 | T cell directives for transcriptional regulation in asthma |
| Q48298645 | T cell receptor gene segment usage in a panel of hen-egg white lysozyme specific, I-Ak-restricted T helper hybridomas |
| Q41791616 | T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3. |
| Q50111962 | T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes |
| Q77584332 | T-Bet expression and failure of GATA-3 cross-regulation lead to default production of IFN-gamma by gammadelta T cells |
| Q43038403 | T-bet Runs INTERFERence |
| Q36399438 | T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes |
| Q53592226 | T-bet controls pathogenicity of CTLs in the heart by separable effects on migration and effector activity. |
| Q33819043 | T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses |
| Q37891668 | T-bet in disease. |
| Q35146723 | T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells |
| Q41862330 | T-bet is required for optimal proinflammatory CD4+ T-cell trafficking. |
| Q37006604 | T-bet plays a key role in NK-mediated control of melanoma metastatic disease |
| Q24650376 | T-bet polymorphisms are associated with asthma and airway hyperresponsiveness |
| Q28588979 | T-bet regulates IgG class switching and pathogenic autoantibody production |
| Q75337265 | T-bet regulates metastasis rate in a murine model of primary prostate cancer |
| Q47765721 | T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells |
| Q28589692 | T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt |
| Q28235100 | T-bet, a T cell-associated transcription factor, is expressed in Hodgkin's lymphoma |
| Q80477829 | T-bet, a T-cell-associated transcription factor, is expressed in a subset of B-cell lymphoproliferative disorders |
| Q33721890 | T-bet, a Th1 transcription factor regulates the expression of Tim-3. |
| Q37576748 | T-bet-/- RAG2-/- ulcerative colitis: the role of T-bet as a peacekeeper of host-commensal relationships |
| Q37320399 | T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function |
| Q34144801 | T-bet-dependent expression of osteopontin contributes to T cell polarization |
| Q38151473 | T-bet: a bridge between innate and adaptive immunity. |
| Q72115600 | T-cell sets that control B-cell secretion of antigen-specific immunoglobulin also control secretion of nonspecific immunoglobulin |
| Q28586793 | TAK1 is an essential regulator of BMP signalling in cartilage |
| Q34985740 | TAK1 mediates BMP signaling in cartilage |
| Q24558608 | TBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroids |
| Q35041384 | TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. |
| Q41696977 | TNF-alpha is expressed on the surface of kidney proximal tubular cells |
| Q37249890 | Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells. |
| Q28392706 | Targeting abnormal ER stress responses in tumors: A new approach to cancer immunotherapy |
| Q88764890 | Targeting skeletal endothelium to ameliorate bone loss |
| Q35909430 | Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy |
| Q34999602 | Tetraspanin CD9 and ectonucleotidase CD73 identify an osteochondroprogenitor population with elevated osteogenic properties |
| Q34690036 | The E3 ubiquitin ligase Wwp2 regulates craniofacial development through mono-ubiquitylation of Goosecoid |
| Q92000954 | The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc |
| Q43926964 | The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex |
| Q35170906 | The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response |
| Q33948105 | The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells |
| Q70531276 | The autologous mixed lymphocyte reaction in strains of mice with autoimmune disease |
| Q24317656 | The basic domain/leucine zipper protein hXBP-1 preferentially binds to and transactivates CRE-like sequences containing an ACGT core |
| Q36342063 | The biologic significance of alloreactivity. The ontogeny of T-cell sets specific for alloantigens or modified self antigens |
| Q37031106 | The daily job of night killers: alternative roles of the BCL-2 family in organelle physiology |
| Q37231726 | The endoplasmic reticulum stress response in immunity and autoimmunity |
| Q37310026 | The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells |
| Q71010679 | The isolation and functional characterization of autoimmune clones expressing inappropriate Ia |
| Q34898008 | The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2 |
| Q36375852 | The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis |
| Q24617740 | The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice |
| Q41210144 | The presence of a DNA binding complex correlates with E beta class II MHC gene expression |
| Q80352679 | The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis |
| Q36804149 | The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. |
| Q72260731 | The proximal promoter of the IL-4 gene is composed of multiple essential regulatory sites that bind at least two distinct factors |
| Q48106384 | The regulatory gene, hXBP-1, and its target, HLA-DRA, utilize both common and distinct regulatory elements and protein complexes |
| Q30379241 | The ripple effect: why promoting female leadership in global health matters. |
| Q36240732 | The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice |
| Q34664905 | The role of Th1/Th2 polarization in mucosal immunity |
| Q72762935 | The specificity of the syngeneic mixed leukocyte response, a primary anti-I region T cell proliferative response, is determined intrathymically |
| Q70226881 | The structure-function relationship of I-A molecules: correlation of serologic and functional phenotypes of four I-Ak mutant cell lines |
| Q45755309 | The transcription T-bet is required for optimal proinflammatory trafficking of CD4+ T cells. |
| Q28508583 | The transcription factor NF-ATc is essential for cardiac valve formation |
| Q28592843 | The transcription factor NFAT4 is involved in the generation and survival of T cells |
| Q36370178 | The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease |
| Q28512302 | The transcription factor XBP-1 is essential for the development and survival of dendritic cells |
| Q34483620 | The transcription factor XBP1 is selectively required for eosinophil differentiation |
| Q28509281 | The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines |
| Q41909224 | The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism |
| Q24321949 | The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes |
| Q24293771 | The unfolded protein response: integrating stress signals through the stress sensor IRE1α |
| Q35615263 | Three distinct signals can induce class II gene expression in a murine pre-B-cell line |
| Q70530992 | Three in vivo promoter phenotypes in MHC class II deficient combined immunodeficiency |
| Q41361316 | Thymic stromal cell specialization and the T-cell receptor repertoire |
| Q36670501 | Thymocyte development in major histocompatibility complex-deficient mice: evidence for stochastic commitment to the CD4 and CD8 lineages |
| Q34170974 | Tissue-specific regulation of cytokine gene expression |
| Q36366273 | Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1 |
| Q34249605 | Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells |
| Q35669762 | Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13 |
| Q78170515 | Transcription factors in lymphocyte development--T and B cells get together |
| Q36361828 | Transcription of the interleukin 4 gene is regulated by multiple promoter elements |
| Q34619808 | Transcription: tantalizing times for T cells |
| Q34079315 | Transcriptional regulation of Th1/Th2 polarization |
| Q41520438 | Transforming growth factor beta 1 repression of the HLA-DR alpha gene is mediated by conserved proximal promoter elements. |
| Q71714695 | Transgenic mice expressing MHC class II molecules with truncated A beta cytoplasmic domains reveal signaling-independent defects in antigen presentation |
| Q72851056 | Transgenic tubular cell expression of class II is insufficient to initiate immune renal injury |
| Q83989386 | Translating research into therapies |
| Q36794291 | Trawling for treasure: tales of T-bet |
| Q33613002 | Truncation of the class II beta-chain cytoplasmic domain influences the level of class II/invariant chain-derived peptide complexes |
| Q57203300 | Trypanosoma cruzi infection in MHC-deficient mice: further evidence for the role of both class I- and class II-restricted T cells in immune resistance and disease |
| Q72749328 | Tumor cells expressing major histocompatibility complex class II and B7 activation molecules stimulate potent tumor-specific immunity |
| Q36369373 | Tumor necrosis factor receptor-associated factor (TRAF)2 represses the T helper cell type 2 response through interaction with NFAT-interacting protein (NIP45). |
| Q29248711 | Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer |
| Q36324925 | Turning down the system: counter-regulatory mechanisms in bone and adaptive immunity |
| Q42943353 | Two levels of help for B cell alloantibody production |
| Q33929276 | Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3 |
| Q36393034 | Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis. |
| Q59071991 | Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex |
| Q44938008 | Upstream elements of the MHC class II E beta gene active in B cells |
| Q78020058 | Using thymus anatomy to dissect T cell repertoire selection |
| Q45941003 | Variable effects of transgenic c-Maf on autoimmune diabetes. |
| Q40819483 | William Erwin Paul (1936-2015). |
| Q28585314 | XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response |
| Q96950814 | XBP-1 and the unfolded protein response (UPR) |
| Q24655821 | XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy |
| Q60613336 | XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy |
| Q28510479 | XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands |
| Q36402768 | XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells |
| Q39659690 | XBP1 Controls Maturation of Gastric Zymogenic Cells by Induction of MIST1 and Expansion of the Rough Endoplasmic Reticulum |
| Q37377432 | XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development |
| Q40519913 | XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. |
| Q22252318 | XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease |
| Q33926690 | XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway |
| Q34345459 | XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation |
| Q28551023 | XBP1-Independent UPR Pathways Suppress C/EBP-β Mediated Chondrocyte Differentiation in ER-Stress Related Skeletal Disease |
| Q37649065 | XBP1: the last two decades |
| Q36401230 | c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms |
| Q33841054 | mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element |
| Q34801417 | p38α MAPK is required for tooth morphogenesis and enamel secretion |
| Q2331722 | Stanley J. Korsmeyer Award | winner | P1346 |
| Q463386 | American Association of Immunologists | chairperson | P488 |
| Q57022669 | Sung-Yun Pai | influenced by | P737 |
| Q42834256 | Laurie Glimcher: merging cell biology and immune function. Interview by Sedwick Caitlin | main subject | P921 |
| Arabic (ar / Q13955) | لوري جليمشر | wikipedia |
| Egyptian Arabic (arz / Q29919) | لورى جليمشر | wikipedia |
| Laurie H. Glimcher | wikipedia | |
| Λώρι Γκλίμτσερ | wikipedia | |
| Laurie Glimcher | wikipedia | |
| Laurie Glimcher | wikipedia | |
| לורי גלימשר | wikipedia | |
| ml | ലോറീ ഗ്ലിംചെർ | wikipedia |
| Глимчер, Лори | wikipedia |
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