scholarly article | Q13442814 |
review article | Q7318358 |
P50 | author | Laurie Glimcher | Q6501587 |
Ann-Hwee Lee | Q124214884 | ||
P2860 | cites work | XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 |
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development | Q24292104 | ||
pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response | Q24303865 | ||
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway | Q24316367 | ||
Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein | Q24555088 | ||
Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription | Q24561983 | ||
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease | Q24805574 | ||
Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase | Q27938837 | ||
Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice | Q28144106 | ||
Proteasome inhibitors disrupt the unfolded protein response in myeloma cells | Q28155919 | ||
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor | Q28238069 | ||
SREBP-1c transcription factor and lipid homeostasis: clinical perspective | Q28291930 | ||
SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation | Q28365331 | ||
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1 | Q28507338 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis | Q28508851 | ||
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver | Q28583240 | ||
Targeted modification of the apolipoprotein B gene results in hypobetalipoproteinemia and developmental abnormalities in mice | Q28584854 | ||
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene | Q28588943 | ||
XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks | Q28591575 | ||
An essential role in liver development for transcription factor XBP-1 | Q28593777 | ||
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver | Q29547646 | ||
The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis. | Q33777806 | ||
Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice | Q33852162 | ||
Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes | Q33878155 | ||
APOLIPOPROTEIN B: mRNA editing, lipoprotein assembly, and presecretory degradation | Q34001437 | ||
Insulin resistance and cardiovascular disease | Q34011027 | ||
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation | Q34345459 | ||
Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1. | Q34451430 | ||
Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis | Q34497858 | ||
Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver | Q34532657 | ||
The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane | Q34673029 | ||
Obesity, metabolic syndrome, and type 2 diabetes: emerging epidemics and their cardiovascular implications | Q35926379 | ||
Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents | Q36183590 | ||
Role of endoplasmic reticulum stress and c-Jun NH2-terminal kinase pathways in inflammation and origin of obesity and diabetes | Q36321560 | ||
XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. | Q36322684 | ||
Metabolic syndrome: focus on dyslipidemia | Q36461906 | ||
Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis | Q36557194 | ||
Clinical practice. Hypertriglyceridemia | Q36931446 | ||
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a | Q37360326 | ||
Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells | Q37364195 | ||
Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice | Q37375695 | ||
Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2. | Q37382401 | ||
The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols | Q38296407 | ||
Glucose and insulin function through two distinct transcription factors to stimulate expression of lipogenic enzyme genes in liver. | Q38305621 | ||
Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice. | Q38311106 | ||
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
The nuclear receptor LXR is a glucose sensor | Q40190911 | ||
Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism | Q40709438 | ||
Regulation of the expression of lipogenic enzyme genes by carbohydrate | Q41548602 | ||
Regulation of sterol regulatory-element binding protein 1 gene expression in liver: role of insulin and protein kinase B/cAkt | Q42996869 | ||
Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes. | Q42997321 | ||
Involvement of a unique carbohydrate-responsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcription | Q43560420 | ||
Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c | Q43848640 | ||
Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER. | Q44317091 | ||
Functional analysis of secreted and transmembrane proteins critical to mouse development. | Q46905044 | ||
Liver-specific inactivation of the abetalipoproteinemia gene completely abrogates very low density lipoprotein/low density lipoprotein production in a viable conditional knockout mouse | Q64381636 | ||
A time-dependent phase shift in the mammalian unfolded protein response | Q72997174 | ||
Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis | Q81441036 | ||
P407 | language of work or name | English | Q1860 |
P304 | page(s) | E2-9 | |
P577 | publication date | 2009-09-01 | |
P1433 | published in | Annals of the New York Academy of Sciences | Q2431664 |
P1476 | title | From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis | |
P478 | volume | 1173 Suppl 1 |
Q34682367 | Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression |
Q90859739 | Angiotensin-converting enzyme 2 inhibits endoplasmic reticulum stress-associated pathway to preserve nonalcoholic fatty liver disease |
Q50580946 | Chemoprotective effect of Vernonia amygdalina Del. (Astereacea) against 2-acetylaminofluorene-induced hepatotoxicity in rats. |
Q30426645 | Constitutive role for IRE1α-XBP1 signaling pathway in the insulin-mediated hepatic lipogenic program |
Q92647941 | Correlation of Dietary Advanced Glycation End Products with the Hematological and Biochemical Markers of Patients with Chronic Kidney Disease Undergoing Hemodialysis |
Q35048017 | Effects on transcriptional regulation and lipid droplet characteristics in the liver of female juvenile pigs after early postnatal feed restriction and refeeding are dependent on birth weight. |
Q33930454 | Elevated systemic expression of ER stress related genes is associated with stress-related mental disorders in the Detroit Neighborhood Health Study |
Q35055531 | Endoplasmic reticulum stress and the unfolded protein response in nonalcoholic fatty liver disease |
Q41889666 | Endoplasmic reticulum stress promotes LIPIN2-dependent hepatic insulin resistance |
Q35986635 | Expression of XBP1s in bone marrow stromal cells is critical for myeloma cell growth and osteoclast formation |
Q39859281 | Genomics of metabolic adaptations in the peripartal cow. |
Q39048675 | Hepatic deletion of X-box binding protein 1 impairs bile acid metabolism in mice |
Q35330118 | Identification of eQTLs for hepatic Xbp1s and Socs3 gene expression in mice fed a high-fat, high-caloric diet. |
Q38816036 | Increased lipogenesis in spite of upregulated hepatic 5'AMP-activated protein kinase in human non-alcoholic fatty liver |
Q42284517 | Insights into the Hexose Liver Metabolism-Glucose versus Fructose |
Q38759104 | Lipotoxicity pathways intersect in hepatocytes: Endoplasmic reticulum stress, c-Jun N-terminal kinase-1, and death receptors |
Q48508155 | Maresin 1 attenuates NAFLD by suppression of endoplasmic reticulum stress via AMPK-SERCA2b pathway |
Q51366583 | Mediterranean diet supplemented with coenzyme Q10 modifies the expression of proinflammatory and endoplasmic reticulum stress-related genes in elderly men and women. |
Q34583052 | Neural dysregulation of peripheral insulin action and blood pressure by brain endoplasmic reticulum stress |
Q43038454 | No increase in the expression of key unfolded protein response genes in HCV genotype 3 patients with severe steatosis |
Q35716234 | PDIA3 Knockdown Exacerbates Free Fatty Acid-Induced Hepatocyte Steatosis and Apoptosis |
Q28577788 | Rapamycin inhibits postprandial-mediated X-box-binding protein-1 splicing in rat liver |
Q26822590 | Role of precursor mRNA splicing in nutrient-induced alterations in gene expression and metabolism |
Q38017716 | Targeting endoplasmic reticulum signaling pathways in cancer |
Q37446318 | The Mediation of Hepatic Lipogenesis Through Estrogens |
Q37412003 | The adaptive endoplasmic reticulum stress response to lipotoxicity in progressive human nonalcoholic fatty liver disease |
Q46273814 | The ins and outs of endoplasmic reticulum-controlled lipid biosynthesis |
Q37867697 | The mechanistic basis for the induction of hepatic steatosis by xenobiotics |
Q24293771 | The unfolded protein response: integrating stress signals through the stress sensor IRE1α |
Q36302806 | Toyocamycin attenuates free fatty acid-induced hepatic steatosis and apoptosis in cultured hepatocytes and ameliorates nonalcoholic fatty liver disease in mice. |
Q42559592 | Tumor progression locus 2 ablation suppressed hepatocellular carcinoma development by inhibiting hepatic inflammation and steatosis in mice |
Q38218108 | Unfolded protein response in hepatitis C virus infection |
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