| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2017PLoSO..1270591T |
| P356 | DOI | 10.1371/JOURNAL.PONE.0170591 |
| P932 | PMC publication ID | 5344317 |
| P698 | PubMed publication ID | 28278289 |
| P50 | author | Yusuke Sakai | Q51719956 |
| Susumu Eguchi | Q85201878 | ||
| P2093 | author name string | Kazuhiko Nakao | |
| Masahiro Nakashima | |||
| Fuminao Takeshima | |||
| Ken Ohnita | |||
| Yuko Akazawa | |||
| Naota Taura | |||
| Katsuya Matsuda | |||
| Hisamitsu Miyaaki | |||
| Yasuko Kanda | |||
| Maiko Tabuchi | |||
| Ikuko Takahara | |||
| Youko Kido | |||
| P2860 | cites work | XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 |
| Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing | Q24627782 | ||
| Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c | Q28297047 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
| An essential role in liver development for transcription factor XBP-1 | Q28593777 | ||
| The natural history of nonalcoholic fatty liver disease: a population-based cohort study | Q29617161 | ||
| ER stress triggers apoptosis by activating BH3-only protein Bim | Q29617730 | ||
| Constitutive role for IRE1α-XBP1 signaling pathway in the insulin-mediated hepatic lipogenic program | Q30426645 | ||
| Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1α-dependent manner | Q30701525 | ||
| Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK/ATF4/CHOP signaling pathway | Q34128069 | ||
| Bax inhibition protects against free fatty acid-induced lysosomal permeabilization | Q34665604 | ||
| Vismodegib suppresses TRAIL-mediated liver injury in a mouse model of nonalcoholic steatohepatitis. | Q34876724 | ||
| ER stress and its regulator X-box-binding protein-1 enhance polyIC-induced innate immune response in dendritic cells. | Q35168302 | ||
| Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis | Q35490178 | ||
| Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition | Q35562084 | ||
| Death receptor 5 signaling promotes hepatocyte lipoapoptosis | Q35604362 | ||
| X-box binding protein 1 (XBP-1) enhances colorectal cancer cell invasion. | Q53612351 | ||
| ERβ decreases breast cancer cell survival by regulating the IRE1/XBP-1 pathway. | Q54313198 | ||
| Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice. | Q54328614 | ||
| Mechanisms underlying hypertriglyceridemia in rats with monosodium L-glutamate-induced obesity: evidence of XBP-1/PDI/MTP axis activation. | Q54447692 | ||
| A new biological role of sangivamycin; inhibition of protein kinases | Q69954354 | ||
| Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis | Q73735584 | ||
| Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis | Q82677113 | ||
| Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis | Q36168809 | ||
| Hepatocyte X-box binding protein 1 deficiency increases liver injury in mice fed a high-fat/sugar diet | Q36382065 | ||
| Hepatic Xbp1 Gene Deletion Promotes Endoplasmic Reticulum Stress-induced Liver Injury and Apoptosis | Q36444262 | ||
| Abnormal lipid and glucose metabolism in obesity: implications for nonalcoholic fatty liver disease | Q36820197 | ||
| JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis | Q37446730 | ||
| From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis | Q37596560 | ||
| Cdc42 and Rac1 are major contributors to the saturated fatty acid-stimulated JNK pathway in hepatocytes | Q38594016 | ||
| Mixed lineage kinase 3 deficient mice are protected against the high fat high carbohydrate diet-induced steatohepatitis. | Q38627620 | ||
| Glycogen synthase kinase-3 (GSK-3) inhibition attenuates hepatocyte lipoapoptosis | Q39621569 | ||
| Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis | Q39731721 | ||
| Transcriptional regulation of Bim by FoxO3A mediates hepatocyte lipoapoptosis | Q40108223 | ||
| High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study | Q41115222 | ||
| The liver's dance with death: two Bcl-2 guardian proteins from the abyss | Q42723851 | ||
| Membrane lipid saturation activates IRE1α without inducing clustering | Q46157031 | ||
| JNK1 but not JNK2 promotes the development of steatohepatitis in mice | Q46865809 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | fatty acid | Q61476 |
| liver disease | Q929737 | ||
| steatosis | Q1365091 | ||
| metabolic dysfunction–associated steatotic liver disease | Q1546498 | ||
| fatty liver disease | Q6058862 | ||
| P304 | page(s) | e0170591 | |
| P577 | publication date | 2017-03-09 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Toyocamycin attenuates free fatty acid-induced hepatic steatosis and apoptosis in cultured hepatocytes and ameliorates nonalcoholic fatty liver disease in mice | |
| P478 | volume | 12 |
| Q45910813 | Artemisia iwayomogi plus Curcuma longa Synergistically Ameliorates Nonalcoholic Steatohepatitis in HepG2 Cells. |
| Q90351791 | Bitter melon extract ameliorates palmitate-induced apoptosis via inhibition of endoplasmic reticulum stress in HepG2 cells and high-fat/high-fructose-diet-induced fatty liver |
| Q92059471 | Calpain-2 activity promotes aberrant endoplasmic reticulum stress-related apoptosis in hepatocytes |
| Q59806057 | Chlorogenic acid against palmitic acid in endoplasmic reticulum stress-mediated apoptosis resulting in protective effect of primary rat hepatocytes |
| Q104073661 | Discovery of a novel fibroblast activation protein (FAP) inhibitor, BR103354, with anti-diabetic and anti-steatotic effects |
| Q33614924 | Effect of mild hypothermia preconditioning against low temperature (4°C) induced rat liver cell injury in vitro |
| Q52629172 | IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma. |
| Q64069791 | Influences of sterol regulatory element binding protein-1c silencing on glucose production in HepG2 cells treated with free fatty acid |
| Q89940295 | Purple sweet potato color protects against hepatocyte apoptosis through Sirt1 activation in high-fat-diet-treated mice |
| Q54119547 | To die or not to die: death signaling in nonalcoholic fatty liver disease. |
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