| scholarly article | Q13442814 |
| P50 | author | Julie Jacquemyn | Q90522165 |
| Rose E Goodchild | Q95949391 | ||
| P2093 | author name string | Ana Cascalho | |
| P2860 | cites work | Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin | Q24290696 |
| Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
| A novel diacylglycerol acyltransferase (DGAT2) is decreased in human psoriatic skin and increased in diabetic mice | Q24296647 | ||
| Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway | Q24298785 | ||
| Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells | Q24301028 | ||
| A conserved phosphatase cascade that regulates nuclear membrane biogenesis | Q24302272 | ||
| SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth | Q24309283 | ||
| Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction | Q24324602 | ||
| Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER | Q24337469 | ||
| Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin | Q24530813 | ||
| The Saccharomyces cerevisiae Lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme | Q24542354 | ||
| Membrane lipids: where they are and how they behave | Q24653084 | ||
| Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes | Q24683425 | ||
| Homeoviscous Adaptation and the Regulation of Membrane Lipids | Q26741039 | ||
| Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling | Q26865945 | ||
| Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae | Q27027569 | ||
| Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
| A phosphorylation-regulated amphipathic helix controls the membrane translocation and function of the yeast phosphatidate phosphatase | Q27930968 | ||
| Phosphatidic acid binding proteins display differential binding as a function of membrane curvature stress and chemical properties. | Q27931119 | ||
| A subfraction of the yeast endoplasmic reticulum associates with the plasma membrane and has a high capacity to synthesize lipids. | Q27932215 | ||
| ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway | Q27932376 | ||
| Intracellular signaling by the unfolded protein response | Q28250477 | ||
| ERAD: the long road to destruction | Q28264823 | ||
| Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns | Q28278069 | ||
| Subcellular organelle lipidomics in TLR-4-activated macrophages | Q28397617 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors | Q28509468 | ||
| Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes | Q28509935 | ||
| XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
| Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway | Q28510620 | ||
| XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks | Q28591575 | ||
| Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes | Q28611357 | ||
| ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response | Q28611502 | ||
| The Lamin B receptor is essential for cholesterol synthesis and perturbed by disease-causing mutations | Q28829592 | ||
| Activation of a metabolic gene regulatory network downstream of mTOR complex 1 | Q29615179 | ||
| Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease | Q29619334 | ||
| Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial | Q29622926 | ||
| Phosphatidylserine synthesis at membrane contact sites promotes its transport out of the ER. | Q30274928 | ||
| Lipin 2 binds phosphatidic acid by the electrostatic hydrogen bond switch mechanism independent of phosphorylation. | Q30384605 | ||
| Human 1-acylglycerol-3-phosphate O-acyltransferase isoforms 1 and 2: biochemical characterization and inability to rescue hepatic steatosis in Agpat2(-/-) gene lipodystrophic mice. | Q30406448 | ||
| Phosphorylation of lipin 1 and charge on the phosphatidic acid head group control its phosphatidic acid phosphatase activity and membrane association | Q30413930 | ||
| mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway | Q30425628 | ||
| A phosphatidic acid binding/nuclear localization motif determines lipin1 function in lipid metabolism and adipogenesis | Q30434066 | ||
| Insulin controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1. | Q30442125 | ||
| Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets. | Q30541918 | ||
| Control of phospholipid synthesis by phosphorylation of the yeast lipin Pah1p/Smp2p Mg2+-dependent phosphatidate phosphatase | Q33257316 | ||
| Activation of the endoplasmic reticulum unfolded protein response by lipid disequilibrium without disturbed proteostasis in vivo | Q33730434 | ||
| Contacts between the endoplasmic reticulum and other membranes in neurons | Q33810341 | ||
| Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity | Q33960868 | ||
| Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity | Q34181503 | ||
| Membranes in balance: mechanisms of sphingolipid homeostasis | Q34330398 | ||
| A unique redox-sensing sensor II motif in TorsinA plays a critical role in nucleotide and partner binding | Q34333556 | ||
| Nonbilayer lipids affect peripheral and integral membrane proteins via changes in the lateral pressure profile. | Q34363960 | ||
| Enzymatic activities of the human AGPAT isoform 3 and isoform 5: localization of AGPAT5 to mitochondria | Q34560731 | ||
| Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans | Q34755232 | ||
| Selective activation of the transcription factor ATF6 mediates endoplasmic reticulum proliferation triggered by a membrane protein | Q34977917 | ||
| Sterol regulatory element-binding proteins: transcriptional activators of lipid synthesis | Q35003607 | ||
| Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis | Q35039363 | ||
| Signaling networks converge on TORC1-SREBP activity to promote endoplasmic reticulum homeostasis. | Q35203849 | ||
| TORC1 regulates Pah1 phosphatidate phosphatase activity via the Nem1/Spo7 protein phosphatase complex | Q35223737 | ||
| Rapid mitogenic regulation of the mTORC1 inhibitor, DEPTOR, by phosphatidic acid | Q35593768 | ||
| A highly dynamic ER-derived phosphatidylinositol-synthesizing organelle supplies phosphoinositides to cellular membranes | Q35607232 | ||
| The unfolded protein response--a stress signaling pathway of the endoplasmic reticulum | Q35885345 | ||
| Intracellular transport of phosphatidylcholine to the plasma membrane | Q36212594 | ||
| Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor Growth | Q36275975 | ||
| The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease | Q38836182 | ||
| Oncogenic PI3K and K-Ras stimulate de novo lipid synthesis through mTORC1 and SREBP. | Q38869139 | ||
| Lipid synthesis and membrane contact sites: a crossroads for cellular physiology | Q38926851 | ||
| A sub-nanometre view of how membrane curvature and composition modulate lipid packing and protein recruitment | Q38956466 | ||
| Lipids and Their Trafficking: An Integral Part of Cellular Organization | Q38990428 | ||
| mTORC1 signaling and the metabolic control of cell growth | Q39243905 | ||
| Membrane contact sites, ancient and central hubs of cellular lipid logistics. | Q39336651 | ||
| A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans | Q39451299 | ||
| Novel mechanism of enhancing IRE1α-XBP1 signalling via the PERK-ATF4 pathway | Q39941630 | ||
| Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism | Q40709438 | ||
| The SREBP pathway in Drosophila: regulation by palmitate, not sterols | Q40752391 | ||
| PHOSPHATIDIC ACID PHOSPHOHYDROLASE Regulates Phosphatidylcholine Biosynthesis in Arabidopsis by Phosphatidic Acid-Mediated Activation of CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE Activity | Q41090052 | ||
| Decrease in membrane phospholipid unsaturation induces unfolded protein response | Q41868507 | ||
| Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2. | Q42033681 | ||
| The budding yeast nuclear envelope adjacent to the nucleolus serves as a membrane sink during mitotic delay | Q42099504 | ||
| Identification of structurally important domains of lipid phosphate phosphatase-1: implications for its sites of action | Q42158591 | ||
| Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance | Q42254249 | ||
| Cholesterol-Independent SREBP-1 Maturation Is Linked to ARF1 Inactivation | Q42257091 | ||
| Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis. | Q42832143 | ||
| Temporal Regulation of Lipin Activity Diverged to Account for Differences in Mitotic Programs | Q43066862 | ||
| Regulation of SREBP processing and membrane lipid production by phospholipids in Drosophila | Q43978685 | ||
| Regulatory effects of HMG CoA reductase inhibitor and fish oils on apolipoprotein B-100 kinetics in insulin-resistant obese male subjects with dyslipidemia. | Q44080980 | ||
| Lipid-induced ER stress: synergistic effects of sterols and saturated fatty acids | Q46080547 | ||
| Efficacy of pitavastatin, a new HMG-CoA reductase inhibitor, on lipid and glucose metabolism in patients with type 2 diabetes | Q46818854 | ||
| What makes the bioactive lipids phosphatidic acid and lysophosphatidic acid so special? | Q46858182 | ||
| Lysophospholipid acyltransferases mediate phosphatidylcholine diversification to achieve the physical properties required in vivo | Q46872309 | ||
| Torsins Are Essential Regulators of Cellular Lipid Metabolism. | Q47070353 | ||
| Activation of the Unfolded Protein Response by Lipid Bilayer Stress. | Q50540191 | ||
| A Metabolic Function for Phospholipid and Histone Methylation. | Q50758057 | ||
| A Eukaryotic Sensor for Membrane Lipid Saturation. | Q50795723 | ||
| Cholesterol-induced conformational changes in the sterol-sensing domain of the Scap protein suggest feedback mechanism to control cholesterol synthesis. | Q51071422 | ||
| Lipid sensing by mTOR complexes via de novo synthesis of phosphatidic acid. | Q51128476 | ||
| Localization, topology, and function of the LCB1 subunit of serine palmitoyltransferase in mammalian cells. | Q51841172 | ||
| Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. | Q53555710 | ||
| Lipid composition of the Golgi apparatus of rat kidney and liver in comparison with other subcellular organelles | Q67292385 | ||
| Kinetic analysis of yeast phosphatidate phosphatase toward Triton X-100/phosphatidate mixed micelles | Q68446661 | ||
| Ultrastructural study of rat liver and liver neoplasms after long-term treatment with phenobarbital | Q70789647 | ||
| Phospholipid biosynthesis program underlying membrane expansion during B-lymphocyte differentiation | Q79527401 | ||
| Diacylglycerol acyltransferase 1 inhibition with AZD7687 alters lipid handling and hormone secretion in the gut with intolerable side effects: a randomized clinical trial | Q86514207 | ||
| XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. | Q36322684 | ||
| PML isoform II plays a critical role in nuclear lipid droplet formation. | Q36428040 | ||
| The relationship between membrane fluidity and permeabilities to water, solutes, ammonia, and protons | Q36435478 | ||
| Signaling functions of phosphatidic acid. | Q36436028 | ||
| Regulation of phospholipid synthesis in the yeast Saccharomyces cerevisiae | Q36589774 | ||
| Conical lipids in flat bilayers induce packing defects similar to that induced by positive curvature | Q36592865 | ||
| Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains | Q36712468 | ||
| The torsin-family AAA+ protein OOC-5 contains a critical disulfide adjacent to Sensor-II that couples redox state to nucleotide binding | Q36796834 | ||
| Phosphatidic acid and lipid-sensing by mTOR | Q36893382 | ||
| Endoplasmic reticulum stress responses | Q37014237 | ||
| Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase | Q37075101 | ||
| ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulum | Q37186859 | ||
| Inhibition of stearoyl-coenzyme A desaturase 1 dissociates insulin resistance and obesity from atherosclerosis | Q37276342 | ||
| Metabolic labeling and direct imaging of choline phospholipids in vivo | Q37340822 | ||
| Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver. | Q37388544 | ||
| Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response. | Q37425584 | ||
| Spatial control of phospholipid flux restricts endoplasmic reticulum sheet formation to allow nuclear envelope breakdown | Q37541029 | ||
| The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis. | Q37562004 | ||
| From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis | Q37596560 | ||
| The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice. | Q37657815 | ||
| Urban planning of the endoplasmic reticulum (ER): how diverse mechanisms segregate the many functions of the ER. | Q37901155 | ||
| Connecting mTORC1 signaling to SREBP-1 activation | Q37997206 | ||
| Structural, mechanistic and regulatory studies of serine palmitoyltransferase | Q38012195 | ||
| Curvature, lipid packing, and electrostatics of membrane organelles: defining cellular territories in determining specificity. | Q38059923 | ||
| Sphingolipid homeostasis in the endoplasmic reticulum and beyond | Q38094869 | ||
| Generation of membrane diversity by lysophospholipid acyltransferases | Q38108686 | ||
| Lipid landscapes and pipelines in membrane homeostasis | Q38217765 | ||
| The role of endoplasmic reticulum stress in human pathology | Q38267105 | ||
| Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways | Q38394944 | ||
| Establishment of NE asymmetry—targeting of membrane proteins to the inner nuclear membrane | Q38537989 | ||
| Membrane lipid compositional sensing by the inducible amphipathic helix of CCT. | Q38690940 | ||
| Taming the sphinx: Mechanisms of cellular sphingolipid homeostasis. | Q38690945 | ||
| P433 | issue | 11 | |
| P921 | main subject | endoplasmic reticulum | Q79927 |
| P304 | page(s) | 1905-1921 | |
| P577 | publication date | 2017-10-26 | |
| P1433 | published in | EMBO Reports | Q5323356 |
| P1476 | title | The ins and outs of endoplasmic reticulum-controlled lipid biosynthesis | |
| P478 | volume | 18 |
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