| Q35289357 | 2-(3-Benzoylthioureido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ameliorates metabolic disorders in high-fat diet-fed mice |
| Q33842841 | A feed-forward loop amplifies nutritional regulation of PNPLA3 |
| Q38122221 | A growing role for mTOR in promoting anabolic metabolism |
| Q33622555 | A mutant of hepatitis B virus X protein (HBxDelta127) promotes cell growth through a positive feedback loop involving 5-lipoxygenase and fatty acid synthase |
| Q38091672 | A pathway approach to investigate the function and regulation of SREBPs |
| Q51538410 | A plant oxysterol, 28-homobrassinolide binds HMGCoA reductase catalytic cleft: stereoselective avidity affects enzyme function. |
| Q24614744 | A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood |
| Q28346400 | A role for smooth endoplasmic reticulum membrane cholesterol ester in determining the intracellular location and regulation of sterol-regulatory-element-binding protein-2 |
| Q33640757 | A systems approach to mapping transcriptional networks controlling surfactant homeostasis |
| Q28583495 | ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose |
| Q36471774 | ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand |
| Q53730590 | Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation. |
| Q28586350 | Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status |
| Q40490395 | Activation domains from both monomers contribute to transcriptional stimulation by sterol regulatory element-binding protein dimers |
| Q37382401 | Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2. |
| Q46260461 | Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver |
| Q34362178 | Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity |
| Q92649647 | Adenosine Monophosphate-Activated Protein Kinase Signaling Regulates Lipid Metabolism in Response to Salinity Stress in the Red-Eared Slider Turtle Trachemys scripta elegans |
| Q41971814 | Adenosine signaling contributes to ethanol-induced fatty liver in mice. |
| Q38343312 | Adipocyte determination- and differentiation-dependent factor 1/sterol regulatory element-binding protein 1c regulates mouse adiponectin expression. |
| Q26828614 | Adipogenesis |
| Q28242180 | Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways |
| Q44768336 | Altered triglyceride-rich lipoprotein production in Zucker diabetic fatty rats |
| Q43948724 | Amelioration of high fructose-induced metabolic derangements by activation of PPARalpha |
| Q39090201 | An R132H mutation in isocitrate dehydrogenase 1 enhances p21 expression and inhibits phosphorylation of retinoblastoma protein in glioma cells |
| Q40658862 | Angiopoietin-like protein 3 mediates hypertriglyceridemia induced by the liver X receptor. |
| Q98386313 | Apple pomace and rosemary extract ameliorates hepatic steatosis in fructose-fed rats: Association with enhancing fatty acid oxidation and suppressing inflammation |
| Q28264722 | Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects? |
| Q48607926 | Association of sterol regulatory element-binding transcription factor gene polymorphisms with ischaemic stroke |
| Q36294936 | Basic aspects of tumor cell fatty acid-regulated signaling and transcription factors. |
| Q36803841 | Beneficial effects of flaxseed oil and fish oil diet are through modulation of different hepatic genes involved in lipid metabolism in streptozotocin-nicotinamide induced diabetic rats |
| Q35935053 | Berberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice |
| Q33785270 | Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c |
| Q37388151 | Blunted feedback suppression of SREBP processing by dietary cholesterol in transgenic mice expressing sterol-resistant SCAP(D443N). |
| Q96155759 | Brahma Related Gene 1 (Brg1) Regulates Cellular Cholesterol Synthesis by Acting as a Co-factor for SREBP2 |
| Q28275445 | CBP is required for sterol-regulated and sterol regulatory element-binding protein-regulated transcription |
| Q40361392 | Caspase-2, a novel lipid sensor under the control of sterol regulatory element binding protein 2. |
| Q38327457 | Cbfa1 isoforms exert functional differences in osteoblast differentiation |
| Q24652984 | Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL |
| Q36806480 | Cholesterol feeding reduces nuclear forms of sterol regulatory element binding proteins in hamster liver |
| Q36776696 | Cholesterol: from feeding to gene regulation |
| Q44695918 | Cholesteryl ester transfer protein modulates the effect of liver X receptor agonists on cholesterol transport and excretion in the mouse |
| Q35210134 | Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro |
| Q64101969 | Cideb controls sterol-regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites |
| Q34424993 | Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2. |
| Q39632629 | Comparison of the pharmacological profiles of murine antisense oligonucleotides targeting apolipoprotein B and microsomal triglyceride transfer protein |
| Q51159954 | Compound K attenuates glucose intolerance and hepatic steatosis through AMPK-dependent pathways in type 2 diabetic OLETF rats. |
| Q27477993 | Critical role of PA28 in hepatitis C virus-associated steatogenesis and hepatocarcinogenesis |
| Q93009314 | Curcumin attenuates insulin resistance and hepatic lipid accumulation in a rat model of intra-uterine growth restriction through insulin signalling pathway and sterol regulatory element binding proteins |
| Q55098613 | Cyp1b1 deletion and retinol deficiency coordinately suppress mouse liver lipogenic genes and hepcidin expression during post-natal development. |
| Q28588943 | Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene |
| Q33706071 | Deficiency of the transcriptional repressor B cell lymphoma 6 (Bcl6) is accompanied by dysregulated lipid metabolism |
| Q34134024 | Dehydrodiconiferyl alcohol isolated from Cucurbita moschata shows anti-adipogenic and anti-lipogenic effects in 3T3-L1 cells and primary mouse embryonic fibroblasts |
| Q34565290 | Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance |
| Q46755385 | Demonstration of diet-induced decoupling of fatty acid and cholesterol synthesis by combining gene expression array and 2H2O quantification |
| Q38653024 | Developmental and extrahepatic physiological functions of SREBP pathway genes in mice |
| Q47411892 | Dietary cholesterol interacts with SREBF1 to modulate obesity in Chinese children |
| Q44168330 | Dietary cholesterol opposes PUFA-mediated repression of the stearoyl-CoA desaturase-1 gene by SREBP-1 independent mechanism |
| Q44356338 | Dietary cholesterol reduces lipoprotein lipase activity in the atherosclerosis-susceptible Bio F(1)B hamster |
| Q35159373 | Dietary fat impacts fetal growth and metabolism: uptake of chylomicron remnant core lipids by the placenta |
| Q38315531 | Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase. |
| Q24561820 | Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells |
| Q34607935 | Differential gene expression in liver and small intestine from lactating rats compared to age-matched virgin controls detects increased mRNA of cholesterol biosynthetic genes |
| Q40559874 | Differential regulation of human and mouse orphan nuclear receptor small heterodimer partner promoter by sterol regulatory element binding protein-1. |
| Q45127806 | Differential regulation of sterol regulatory element-binding protein 1c transcriptional activity by insulin and liver X receptor during liver development |
| Q28646552 | Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins |
| Q34166238 | Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance. |
| Q43848640 | Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c |
| Q92288892 | Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor |
| Q28281340 | Direct interaction between USF and SREBP-1c mediates synergistic activation of the fatty-acid synthase promoter |
| Q34343429 | Disease model: hyperinsulinemia and insulin resistance. Part B--polygenic and other animal models. |
| Q33849024 | Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL |
| Q37472798 | Dissecting the role of insulin resistance in the metabolic syndrome |
| Q38050214 | Dissociating fatty liver and diabetes |
| Q33260941 | Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: marked differences between various antipsychotic drugs |
| Q26866577 | Dual functions of Insig proteins in cholesterol homeostasis |
| Q37033133 | E4BP4 is an insulin-induced stabilizer of nuclear SREBP-1c and promotes SREBP-1c-mediated lipogenesis. |
| Q35313420 | Early growth response 1 (Egr1) regulates cholesterol biosynthetic gene expression |
| Q33735936 | Early hepatic insulin resistance in mice: a metabolomics analysis |
| Q44504918 | Effect of carbamates on mRNA encoding lipid enzymes in hamster flank organs |
| Q35053466 | Effects of HIV protease inhibitor therapy on lipid metabolism |
| Q34855807 | Effects of fatty acids on gene expression: role of peroxisome proliferator-activated receptor alpha, liver X receptor alpha and sterol regulatory element-binding protein-1c |
| Q35834373 | Effects of sterol regulatory element-binding protein (SREBP) in chickens |
| Q37722414 | Elaidic acid increases hepatic lipogenesis by mediating sterol regulatory element binding protein-1c activity in HuH-7 cells |
| Q28584842 | Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene |
| Q36410781 | Enhanced Nrf2 activity worsens insulin resistance, impairs lipid accumulation in adipose tissue, and increases hepatic steatosis in leptin-deficient mice. |
| Q54753378 | Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP-1c Tg mice fed high-fat and high-fructose diet. |
| Q28588424 | Essential role in vivo of upstream stimulatory factors for a normal dietary response of the fatty acid synthase gene in the liver |
| Q44679119 | Evaluation of the therapeutic potential of PPARalpha agonists for X-linked adrenoleukodystrophy. |
| Q37426801 | Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been |
| Q34231924 | Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation |
| Q53403848 | Expression of receptor-Ck and SREBP genes in mononuclear cells from acute leukemia patients. |
| Q34656377 | Farnesol decreases serum triglycerides in rats: identification of mechanisms including up-regulation of PPARalpha and down-regulation of fatty acid synthase in hepatocytes |
| Q27319798 | Fat Metabolism Regulates Satiety Behavior in C. elegans. |
| Q42719792 | Fat metabolism is regulated by altered gene expression of lipogenic enzymes and regulatory factors in liver and adipose tissue but not in semimembranosus muscle of pigs during the fattening period |
| Q89980482 | Fatty acid biosynthesis and transcriptional regulation of Stearoyl-CoA Desaturase 1 (SCD1) in buffalo milk |
| Q44364018 | Fatty acid flux suppresses fatty acid synthesis in hamster intestine independently of SREBP-1 expression |
| Q35648897 | Fibroblast growth factor 21 prevents atherosclerosis by suppression of hepatic sterol regulatory element-binding protein-2 and induction of adiponectin in mice. |
| Q50864371 | Fisetin protects against hepatosteatosis in mice by inhibiting miR-378. |
| Q37596560 | From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis |
| Q34668012 | Fructus Xanthii attenuates hepatic steatosis in rats fed on high-fat diet |
| Q39395189 | G0S2: A small giant controller of lipolysis and adipose-liver fatty acid flux. |
| Q37170811 | GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice |
| Q91831481 | Gene expression and DNA methylation as mechanisms of disturbed metabolism in offspring after exposure to a prenatal HF diet |
| Q50422447 | Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance. |
| Q38295871 | Genotype of bovine sterol regulatory element binding protein-1 (SREBP-1) is associated with fatty acid composition in Japanese Black cattle. |
| Q41482101 | Gestational disruptions in metabolic rhythmicity of the liver, muscle, and placenta affect fetal size. |
| Q38305621 | Glucose and insulin function through two distinct transcription factors to stimulate expression of lipogenic enzyme genes in liver. |
| Q30988773 | Glucose regulation of the acetyl-CoA carboxylase promoter PI in rat hepatocytes |
| Q42149934 | HCBP6 Modulates Triglyceride Homeostasis in Hepatocytes Via the SREBP1c/FASN Pathway |
| Q43730373 | HIV protease inhibitor induces fatty acid and sterol biosynthesis in liver and adipose tissues due to the accumulation of activated sterol regulatory element-binding proteins in the nucleus |
| Q54367643 | Haplotype combination of SREBP-1c gene sequence variants is associated with growth traits in cattle. |
| Q34094336 | Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemia |
| Q24300790 | Hepatic PCSK9 expression is regulated by nutritional status via insulin and sterol regulatory element-binding protein 1c |
| Q36185317 | Hepatic S1P deficiency lowers plasma cholesterol levels in apoB-containing lipoproteins when LDLR function is compromised. |
| Q28581281 | Hepatic farnesyl diphosphate synthase expression is suppressed by polyunsaturated fatty acids |
| Q64967030 | Hepatic fatty acid biosynthesis in KK-Ay mice is modulated by administration of persimmon peel extract: A DNA microarray study. |
| Q37665444 | Hepatic insulin receptor deficiency impairs the SREBP-2 response to feeding and statins |
| Q34804981 | Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2 |
| Q35104088 | Hepatic oxidative stress promotes insulin-STAT-5 signaling and obesity by inactivating protein tyrosine phosphatase N2 |
| Q37321860 | Hepatic triacylglycerol accumulation and insulin resistance. |
| Q91062570 | Hepatic triglyceride accumulation via endoplasmic reticulum stress-induced SREBP-1 activation is regulated by ceramide synthases |
| Q35800315 | Hepatitis C virus to hepatocellular carcinoma. |
| Q47428749 | Hepatocyte-specific deletion of BAP31 promotes SREBP1C activation, promotes hepatic lipid accumulation, and worsens IR in mice |
| Q90384304 | High Energy Intake Induced Overexpression of Transcription Factors and Its Regulatory Genes Involved in Acceleration of Hepatic Lipogenesis: A Rat Model for Type 2 Diabetes |
| Q84106773 | High dietary protein combats the stress of Labeo rohita fingerlings exposed to heat shock |
| Q33474784 | High fat feeding induces hepatic fatty acid elongation in mice |
| Q33220241 | High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding |
| Q50199746 | Hippo-mediated suppression of IRS2/AKT signaling prevents hepatic steatosis and liver cancer |
| Q43260810 | Hypoxia aggravates non-alcoholic steatohepatitis in mice lacking hepatocellular PTEN. |
| Q37302297 | Hypoxia-inducible factor 2 regulates hepatic lipid metabolism |
| Q33988649 | IGF-1 induces SREBP-1 expression and lipogenesis in SEB-1 sebocytes via activation of the phosphoinositide 3-kinase/Akt pathway. |
| Q37832539 | Identification and utilization of genes associated with beef qualities |
| Q58244290 | Identification of Ku70/Ku80 as ADD1/SREBP1c interacting proteins |
| Q24550969 | Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter |
| Q40022597 | In vivo and in vitro effects of SREBP-1 on diabetic renal tubular lipid accumulation and RNAi-mediated gene silencing study |
| Q37264829 | Inability to fully suppress sterol synthesis rates with exogenous sterol in embryonic and extraembyronic fetal tissues |
| Q28243492 | Increased cholesterol biosynthesis and hypercholesterolemia in mice overexpressing squalene synthase in the liver |
| Q38297185 | Increased expression of the sterol regulatory element-binding protein-1 gene in insulin receptor substrate-2(-/-) mouse liver |
| Q33846866 | Inhibition of SREBP1 sensitizes cells to death ligands. |
| Q35562476 | Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice |
| Q28820975 | Inhibition of vascular endothelial growth factor signaling facilitates liver repair from acute ethanol-induced injury in zebrafish |
| Q39531917 | Inhibitory effect of schisandrin B on free fatty acid-induced steatosis in L-02 cells. |
| Q40753400 | Insig: a significant integrator of nutrient and hormonal signals |
| Q36466124 | Insulin Dissociates the Effects of Liver X Receptor on Lipogenesis, Endoplasmic Reticulum Stress, and Inflammation. |
| Q42053294 | Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1 and NF-Y cis-acting elements |
| Q46869784 | Insulin regulation of glucokinase gene expression: evidence against a role for sterol regulatory element binding protein 1 in primary hepatocytes. |
| Q35210714 | Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy |
| Q36698641 | Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes |
| Q36838847 | Insulin signalling mechanisms for triacylglycerol storage |
| Q40584941 | Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding Protein-2 at serine residues 432 and 455 in vivo. |
| Q37788976 | Interaction of the hepatitis C virus (HCV) core with cellular genes in the development of HCV-induced steatosis. |
| Q34985745 | Intersection of the unfolded protein response and hepatic lipid metabolism |
| Q53434266 | Involvement of microRNA214 and transcriptional regulation in reductions in mevalonate pyrophosphate decarboxylase mRNA levels in stroke-prone spontaneously hypertensive rat livers. |
| Q44557334 | Involvement of the SREBP pathway in the mode of action of androgens in sebaceous glands in vivo |
| Q73849660 | Ion channels formed by transcription factors recognize consensus DNA sequences |
| Q42819162 | Isolation of cholesterol-requiring mutant Chinese hamster ovary cells with defects in cleavage of sterol regulatory element-binding proteins at site 1. |
| Q58699594 | JAZF1 ameliorates age and diet-associated hepatic steatosis through SREBP-1c -dependent mechanism |
| Q37098581 | Keratinocyte growth factor induces lipogenesis in alveolar type II cells through a sterol regulatory element binding protein-1c-dependent pathway |
| Q34428893 | LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice. |
| Q88761261 | Lipid metabolism reprogramming and its potential targets in cancer |
| Q34102929 | Lipoic acid entrains the hepatic circadian clock and lipid metabolic proteins that have been desynchronized with advanced age. |
| Q81127015 | Lipotoxicity, an imbalance between lipogenesis de novo and fatty acid oxidation |
| Q34519854 | Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiation |
| Q37646873 | Liver X receptor α mediates hepatic triglyceride accumulation through upregulation of G0/G1 Switch Gene 2 expression |
| Q37015068 | Liver kinase b1 is required for white adipose tissue growth and differentiation |
| Q27010631 | Liver steatosis in hepatitis C patients |
| Q34171384 | Liver-specific expression of transcriptionally active SREBP-1c is associated with fatty liver and increased visceral fat mass |
| Q61135312 | Long noncoding RNA licensing of obesity-linked hepatic lipogenesis and NAFLD pathogenesis |
| Q57794656 | Loss of progesterone receptor membrane component 1 promotes hepatic steatosis via the induced de novo lipogenesis |
| Q37308701 | Loss of protein kinase Cbeta function protects mice against diet-induced obesity and development of hepatic steatosis and insulin resistance |
| Q47132548 | Lunasin functionally enhances LDL uptake via inhibiting PCSK9 and enhancing LDLR expression in vitro and in vivo |
| Q28142130 | MAP kinases Erk1/2 phosphorylate sterol regulatory element-binding protein (SREBP)-1a at serine 117 in vitro |
| Q28609710 | Maintaining cholesterol homeostasis: sterol regulatory element-binding proteins |
| Q45075424 | Maternal dietary iron restriction modulates hepatic lipid metabolism in the fetuses. |
| Q38770951 | Mechanistic insight into nuclear receptor-mediated regulation of bile acid metabolism and lipid homeostasis by grape seed procyanidin extract (GSPE). |
| Q37097833 | Mediating lipid biosynthesis: implications for cardiovascular disease |
| Q91782011 | MiR-455 targeting SOCS3 improve liver lipid disorders in diabetic mice |
| Q37394060 | MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice. |
| Q39195873 | MicroRNAs and lipid metabolism. |
| Q92234951 | Mitochondrial dysfunction stimulates HBV gene expression through lipogenic transcription factor activation |
| Q22254257 | Molecular characterization of human acetyl-CoA synthetase, an enzyme regulated by sterol regulatory element-binding proteins |
| Q33946830 | Molecular link between cholesterol, cytokines and atherosclerosis |
| Q33585604 | Molecular mechanisms involved in hepatic steatosis and insulin resistance |
| Q37078754 | Molecular mechanisms of alcoholic fatty liver |
| Q89220189 | Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease |
| Q37171127 | Molecular mechanisms of hepatic steatosis and insulin resistance in the AGPAT2-deficient mouse model of congenital generalized lipodystrophy |
| Q29616709 | Molecular mediators of hepatic steatosis and liver injury |
| Q37972887 | Molecular pathology of familial hypercholesterolemia, related dyslipidemias and therapies beyond the statins |
| Q35723508 | Molecular regulation of SREBP function: the Insig-SCAP connection and isoform-specific modulation of lipid synthesis |
| Q27486807 | Mouse models for the study of HCV infection and virus–host interactions |
| Q34682304 | New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c |
| Q42806308 | Nonalcoholic Fatty liver disease: focus on lipoprotein and lipid deregulation |
| Q90580543 | Novel Lipid Long Intervening Noncoding RNA, Oligodendrocyte Maturation-Associated Long Intergenic Noncoding RNA, Regulates the Liver Steatosis Gene Stearoyl-Coenzyme A Desaturase As an Enhancer RNA |
| Q26746261 | Nutrigenomics and Beef Quality: A Review about Lipogenesis |
| Q34451430 | Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1. |
| Q37254332 | Nutritional regulation of the fatty acid synthase promoter in vivo: sterol regulatory element binding protein functions through an upstream region containing a sterol regulatory element |
| Q36617551 | Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications |
| Q41018678 | Oleate potentiates oxysterol inhibition of transcription from sterol regulatory element-1-regulated promoters and maturation of sterol regulatory element-binding proteins |
| Q38981911 | Omega-3 fatty acid enriched chevon (goat meat) lowers plasma cholesterol levels and alters gene expressions in rats. |
| Q44509776 | Overexpression of sterol regulatory element-binding protein-1a in mouse adipose tissue produces adipocyte hypertrophy, increased fatty acid secretion, and fatty liver. |
| Q51502306 | Overweight induced by chronic risperidone exposure is correlated with overexpression of the SREBP-1c and FAS genes in mouse liver. |
| Q42751911 | PAS kinase drives lipogenesis through SREBP-1 maturation. |
| Q40923110 | PI3K-Akt signaling pathway upregulates hepatitis C virus RNA translation through the activation of SREBPs |
| Q42403132 | Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets |
| Q35662330 | Pathogenesis of selective insulin resistance in isolated hepatocytes |
| Q38289039 | Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin |
| Q39130252 | Phospho-mTOR: a novel target in regulation of renal lipid metabolism abnormality of diabetes |
| Q49706850 | Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP. |
| Q46308032 | Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples |
| Q37158095 | Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes |
| Q24534942 | Polyunsaturated fatty acids decrease the expression of sterol regulatory element-binding protein-1 in CaCo-2 cells: effect on fatty acid synthesis and triacylglycerol transport |
| Q39741460 | Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit. |
| Q31742604 | Polyunsaturated fatty acids suppress hepatic sterol regulatory element-binding protein-1 expression by accelerating transcript decay |
| Q43764702 | Post-transcriptional stimulation of the assembly and secretion of triglyceride-rich apolipoprotein B lipoproteins in a mouse with selective deficiency of brown adipose tissue, obesity, and insulin resistance |
| Q38301574 | Potent effects of dioscin against obesity in mice |
| Q34182797 | Preventing phosphorylation of sterol regulatory element-binding protein 1a by MAP-kinases protects mice from fatty liver and visceral obesity |
| Q37148306 | Pro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRα expression and cholesterol homeostasis |
| Q40864894 | Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene |
| Q39328599 | Protective effects of dioscin against alcohol-induced liver injury |
| Q51478386 | Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver. |
| Q39735993 | Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin. |
| Q90019833 | Proteolytic Control of Lipid Metabolism |
| Q59133408 | Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN |
| Q38350285 | Quantitation of the sterol regulatory element-binding protein mRNA in mononuclear blood cells by competitive RT-PCR |
| Q56541822 | RETRACTED: Reversion of hepatic steatosis by exercise training in obese mice: the role of sterol regulatory element-binding protein-1c |
| Q91635371 | Recent Insights Into SREBP as a Direct Mediator of Kidney Fibrosis via Lipid-Independent Pathways |
| Q47886867 | Receptor-Ck and leukemogenesis |
| Q47783376 | Receptor-Ck controls the expression of Bcl-2 and cyclin d genes |
| Q47098397 | Reduced sterol regulatory element-binding protein (SREBP) processing through site-1 protease (S1P) inhibition alters oligodendrocyte differentiation in vitro |
| Q57065546 | Regulation and Metabolic Significance of Lipogenesis in Adipose Tissues |
| Q45208068 | Regulation of SREBP-1 expression and transcriptional action on HKII and FAS genes during fasting and refeeding in rat tissues |
| Q36886903 | Regulation of SREBP-Mediated Gene Expression |
| Q37866898 | Regulation of cholesterol and fatty acid synthesis |
| Q44280816 | Regulation of fatty acid synthase expression in breast cancer by sterol regulatory element binding protein-1c |
| Q37996638 | Regulation of gene transcription by fatty acids. |
| Q33816670 | Regulation of hepatic gene expression by saturated fatty acids |
| Q37847726 | Regulation of lipid homeostasis by the bifunctional SREBF2-miR33a locus |
| Q28268591 | Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1 |
| Q40779880 | Regulation of lipoprotein lipase by the oxysterol receptors, LXRalpha and LXRbeta. |
| Q24598068 | Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta |
| Q39446637 | Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism |
| Q37375695 | Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice |
| Q42501993 | Regulation of sterol regulatory element-binding proteins in hamster intestine by changes in cholesterol flux |
| Q34169224 | Regulation of the angiopoietin-like protein 3 gene by LXR. |
| Q60956914 | Regulatory Efficacy of Protease Hydrolyzate on Lipid Metabolism and Gut Microbiota in High-Fat Diet-Fed Rats |
| Q40567001 | Restoration of sterol-regulatory-element-binding protein-1c gene expression in HepG2 cells by peroxisome-proliferator-activated receptor-gamma co-activator-1alpha |
| Q84540214 | Reversible stress-induced lipid body formation in fast twitch rat myofibers |
| Q43903250 | Role of sterol regulatory element-binding protein 1 in regulation of renal lipid metabolism and glomerulosclerosis in diabetes mellitus. |
| Q36020648 | Role of the liver in the control of carbohydrate and lipid homeostasis |
| Q64966841 | SCAP/SREBPs are Central Players in Lipid Metabolism and Novel Metabolic Targets in Cancer Therapy. |
| Q24298588 | SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism |
| Q93147449 | SREBF1c and SREBF2 gene polymorphisms are associated with acute coronary syndrome and blood lipid levels in Mexican population |
| Q83827454 | SREBP activation by antipsychotic- and antidepressant-drugs in cultured human liver cells: relevance for metabolic side-effects? |
| Q28365331 | SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation |
| Q44308547 | SREBP-1 integrates the actions of thyroid hormone, insulin, cAMP, and medium-chain fatty acids on ACCalpha transcription in hepatocytes |
| Q34289658 | SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes. |
| Q52578686 | SREBP-1-independent regulation of lipogenic gene expression in adipocytes. |
| Q28240899 | SREBP-1c and Sp1 interact to regulate transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) in the liver |
| Q36728656 | SREBP-1c and TFE3, energy transcription factors that regulate hepatic insulin signaling |
| Q58114538 | SREBP-1c-Dependent Metabolic Remodeling of White Adipose Tissue by Caloric Restriction |
| Q36617459 | SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression |
| Q47692117 | SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology |
| Q47868873 | SREBPs suppress IRS-2-mediated insulin signalling in the liver |
| Q29547646 | SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver |
| Q37966406 | SREBPs: metabolic integrators in physiology and metabolism |
| Q33813669 | Sasa borealis stem extract attenuates hepatic steatosis in high-fat diet-induced obese rats |
| Q37512959 | Schisandra chinensis prevents alcohol-induced fatty liver disease in rats |
| Q28509016 | Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins |
| Q38339593 | Selective association of sterol regulatory element-binding protein isoforms with target promoters in vivo |
| Q39962049 | Selective coactivator interactions in gene activation by SREBP-1a and -1c. |
| Q38331700 | Short-term inhibition of SREBP-1c expression reverses diet-induced non-alcoholic fatty liver disease in mice. |
| Q36485655 | Signalling mechanisms linking hepatic glucose and lipid metabolism |
| Q39975300 | Silencing of hepatic fatty acid transporter protein 5 in vivo reverses diet-induced non-alcoholic fatty liver disease and improves hyperglycemia |
| Q37157638 | Sirtuin 1 deacetylase: a key regulator of hepatic lipid metabolism |
| Q45171650 | Sixteen hours of fasting differentially affects hepatic and muscle insulin sensitivity in mice |
| Q36339529 | Skeletal muscle insulin resistance promotes increased hepatic de novo lipogenesis, hyperlipidemia, and hepatic steatosis in the elderly |
| Q46581275 | Soy protein reduces hepatic lipotoxicity in hyperinsulinemic obese Zucker fa/fa rats |
| Q31157296 | Spatial distribution and function of sterol regulatory element-binding protein 1a and 2 homo- and heterodimers by in vivo two-photon imaging and spectroscopy fluorescence resonance energy transfer |
| Q60060706 | Squalene synthase: Structure and regulation |
| Q35619570 | Srebf1a is a key regulator of transcriptional control for adipogenesis |
| Q44832224 | Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms |
| Q35049666 | Stearoyl-CoA desaturase, a short-lived protein of endoplasmic reticulum with multiple control mechanisms |
| Q35071237 | Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation |
| Q45223740 | Steatohepatitis develops rapidly in transgenic mice overexpressing Abcb11 and fed a methionine-choline-deficient diet |
| Q37622162 | Steatosis and insulin resistance in hepatitis C: a way out for the virus? |
| Q38165140 | Steatosis in the liver. |
| Q40589206 | Sterol regulation of scavenger receptor class B type I in macrophages |
| Q28511448 | Sterol regulatory element binding protein 1a regulates hepatic fatty acid partitioning by activating acetyl coenzyme A carboxylase 2 |
| Q77126907 | Sterol regulatory element binding protein-1 activates the cholesteryl ester transfer protein gene in vivo but is not required for sterol up-regulation of gene expression |
| Q33878155 | Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes |
| Q44000276 | Sterol regulatory element binding proteins: relationship of adipose tissue gene expression with obesity in humans |
| Q28257929 | Sterol regulatory element-binding protein (SREBP)-1: gene regulatory target for insulin resistance? |
| Q35025259 | Sterol regulatory element-binding protein family as global regulators of lipid synthetic genes in energy metabolism |
| Q37608436 | Sterol regulatory element-binding protein-1 (SREBP-1) is required to regulate glycogen synthesis and gluconeogenic gene expression in mouse liver |
| Q28646399 | Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes |
| Q43783320 | Sterol regulatory element-binding protein-1c is responsible for cholesterol regulation of ileal bile acid-binding protein gene in vivo. Possible involvement of liver-X-receptor. |
| Q24307756 | Sterol regulatory element-binding protein-2 interacts with hepatocyte nuclear factor-4 to enhance sterol isomerase gene expression in hepatocytes |
| Q33996668 | Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action |
| Q28611357 | Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes |
| Q34460031 | Sterol regulatory element-binding proteins and reactive oxygen species: potential role in highly-active antiretroviral therapy (HAART)-associated lipodystrophy |
| Q44064875 | Sterol-regulatory element-binding protein (SREBP)-2 contributes to polygenic hypercholesterolaemia |
| Q51396709 | Sterol-regulatory-element-binding protein 1c mediates the effect of insulin on the expression of Cidea in mouse hepatocytes. |
| Q73155215 | Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway |
| Q28139740 | Structure and regulation of mammalian squalene synthase |
| Q37431796 | Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity |
| Q42856791 | Suppression of the pancreatic duodenal homeodomain transcription factor-1 (Pdx-1) promoter by sterol regulatory element-binding protein-1c (SREBP-1c). |
| Q28551941 | Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease |
| Q58694274 | TFAP2 transcription factors are regulators of lipid droplet biogenesis |
| Q99712026 | Targeting SREBP-2-Regulated Mevalonate Metabolism for Cancer Therapy |
| Q92177891 | The Administration of Chitosan-Tripolyphosphate-DNA Nanoparticles to Express Exogenous SREBP1a Enhances Conversion of Dietary Carbohydrates into Lipids in the Liver of Sparus aurata |
| Q40714730 | The E-box like sterol regulatory element mediates the suppression of human Delta-6 desaturase gene by highly unsaturated fatty acids |
| Q40782874 | The FIRE3-mediated sterol response of the FAS promoter requires NF-Y/CBF as a coactivator |
| Q37723259 | The SCAP/SREBP Pathway: A Mediator of Hepatic Steatosis |
| Q34223258 | The SREBP pathway--insights from Insigs and insects |
| Q28238069 | The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor |
| Q24654991 | The blind men 'see' the elephant-the many faces of fatty liver disease |
| Q34642326 | The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis |
| Q36364289 | The effects of PCB126 on intra-hepatic mechanisms associated with non alcoholic fatty liver disease. |
| Q36922115 | The effects of chronic AMPK activation on hepatic triglyceride accumulation and glycerol 3-phosphate acyltransferase activity with high fat feeding |
| Q37196034 | The effects of prenatal metformin on obesogenic diet-induced alterations in maternal and fetal fatty acid metabolism |
| Q34494671 | The extended TILAR approach: a novel tool for dynamic modeling of the transcription factor network regulating the adaption to in vitro cultivation of murine hepatocytes |
| Q45195807 | The gene encoding acyl-CoA-binding protein is subject to metabolic regulation by both sterol regulatory element-binding protein and peroxisome proliferator-activated receptor alpha in hepatocytes |
| Q101038911 | The impact of endotrophin on the progression of chronic liver disease |
| Q34769303 | The international workshop on meibomian gland dysfunction: report of the subcommittee on anatomy, physiology, and pathophysiology of the meibomian gland |
| Q40524290 | The liver X receptor ligand T0901317 down-regulates APOA5 gene expression through activation of SREBP-1c |
| Q35866478 | The liver plays a key role in whole body sterol accretion of the neonatal Golden Syrian hamster |
| Q36659049 | The multifaceted role of mTORC1 in the control of lipid metabolism |
| Q40973550 | The physiological role of sterol regulatory element-binding protein-2 in cultured human cells |
| Q43997258 | The role of SREBP-1c in nutritional regulation of lipogenic enzyme gene expression |
| Q35090215 | The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance. |
| Q38526403 | The roles of sterol regulatory element-binding proteins in the transactivation of the rat ATP citrate-lyase promoter. |
| Q45094313 | The trans-10,cis-12 isomer of conjugated linoleic acid reduces hepatic triacylglycerol content without affecting lipogenic enzymes in hamsters |
| Q44324677 | The transcription factor SREBP-1c is instrumental in the development of beta-cell dysfunction |
| Q44652125 | The transcription factors HIF-1 and HNF-4 and the coactivator p300 are involved in insulin-regulated glucokinase gene expression via the phosphatidylinositol 3-kinase/protein kinase B pathway |
| Q34708310 | Thematic review series: skin lipids. Sebaceous gland lipids: friend or foe? |
| Q36061138 | Thyroid hormone receptor-α gene knockout mice are protected from diet-induced hepatic insulin resistance |
| Q37650762 | Transcriptional and post-translational regulation of adiponectin |
| Q96228328 | Transcriptional regulation mechanism of SREBP on Δ6 Fad in razor clam Sinonovacula constricta |
| Q26778594 | Transcriptional regulation of hepatic lipogenesis |
| Q40884672 | Transcriptional regulation of the ATP citrate-lyase gene by sterol regulatory element-binding proteins |
| Q24633793 | Twist2, a novel ADD1/SREBP1c interacting protein, represses the transcriptional activity of ADD1/SREBP1c |
| Q45336941 | Two novel coding SNPs of SREBP1c gene are associated with body weight and average daily gain in bovine |
| Q35926317 | Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR. |
| Q44090304 | Up-regulation of SREBP-1c and lipogenic genes in skeletal muscles after exercise training |
| Q21134517 | Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease |
| Q28354289 | Xylobiose, an Alternative Sweetener, Ameliorates Diabetes-Related Metabolic Changes by Regulating Hepatic Lipogenesis and miR-122a/33a in db/db Mice |
| Q50889958 | Zinc mediates the SREBP-SCD axis to regulate lipid metabolism in Caenorhabditis elegans. |
| Q33678751 | alpha(1)-fetoprotein transcription factor (FTF)/liver receptor homolog-1 (LRH-1) is an essential lipogenic regulator |
| Q28252695 | mTOR signaling in tumorigenesis |
| Q35652651 | mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC). |
| Q41034686 | microRNA-29 mediates a novel negative feedback loop to regulate SCAP/SREBP-1 and lipid metabolism |
| Q55358970 | p300/CBP as a Key Nutritional Sensor for Hepatic Energy Homeostasis and Liver Fibrosis. |
| Q40195480 | p38 mitogen-activated protein kinase plays an inhibitory role in hepatic lipogenesis |
| Q38354871 | p53 Activation in Adipocytes of Obese Mice |
| Q37369567 | α-Linolenic acid suppresses cholesterol and triacylglycerol biosynthesis pathway by suppressing SREBP-2, SREBP-1a and -1c expression |
| Q24531878 | Functional antagonism between inhibitor of DNA binding (Id) and adipocyte determination and differentiation factor 1/sterol regulatory element-binding protein-1c (ADD1/SREBP-1c) trans-factors for the regulation of fatty acid synthase promoter in adi |