review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Laurie Glimcher | Q6501587 |
Ann-Hwee Lee | Q124214884 | ||
P2860 | cites work | Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase | Q22010589 |
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 | ||
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease | Q22252318 | ||
Role of LXRs in control of lipogenesis | Q24290548 | ||
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs | Q24290776 | ||
Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response | Q24290935 | ||
Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development | Q24292104 | ||
Loss of kinase activity in a patient with Wolcott-Rallison syndrome caused by a novel mutation in the EIF2AK3 gene | Q24300493 | ||
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells | Q24309442 | ||
SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis | Q24310555 | ||
The basic domain/leucine zipper protein hXBP-1 preferentially binds to and transactivates CRE-like sequences containing an ACGT core | Q24317656 | ||
Glucose activates ChREBP by increasing its rate of nuclear entry and relieving repression of its transcriptional activity | Q24336875 | ||
Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control | Q24522941 | ||
A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha | Q24548092 | ||
Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response | Q24548363 | ||
Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription | Q24561983 | ||
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta | Q24598068 | ||
Organelle biogenesis and intracellular lipid transport in eukaryotes | Q24634717 | ||
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival | Q24653078 | ||
Different types of ground glass hepatocytes in chronic hepatitis B virus infection contain specific pre-S mutants that may induce endoplasmic reticulum stress | Q24672497 | ||
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
Oxidative protein folding in eukaryotes: mechanisms and consequences | Q24676827 | ||
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes | Q24683425 | ||
Flavivirus Infection Activates the XBP1 Pathway of the Unfolded Protein Response To Cope with Endoplasmic Reticulum Stress | Q27477652 | ||
Subcellular forms and biochemical events triggered in human cells by HCV polyprotein expression from a viral vector | Q27486946 | ||
Hepatitis C Virus Infection Induces Apoptosis through a Bax-Triggered, Mitochondrion-Mediated, Caspase 3-Dependent Pathway | Q27487135 | ||
Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
Phospholipid metabolism regulated by a transcription factor sensing phosphatidic acid. | Q27930626 | ||
A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus | Q27930818 | ||
Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway | Q27932953 | ||
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response | Q27933479 | ||
Functional characterization of an inositol-sensitive upstream activation sequence in yeast. A cis-regulatory element responsible for inositol-choline mediated regulation of phospholipid biosynthesis | Q27935042 | ||
IRE1 encodes a putative protein kinase containing a membrane-spanning domain and is required for inositol phototrophy in Saccharomyces cerevisiae | Q27935778 | ||
The unfolded protein response pathway in Saccharomyces cerevisiae. Oligomerization and trans-phosphorylation of Ire1p (Ern1p) are required for kinase activation | Q27936284 | ||
A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response | Q27938493 | ||
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase | Q27938837 | ||
tRNA ligase is required for regulated mRNA splicing in the unfolded protein response | Q27940124 | ||
Lipid metabolism and vesicle trafficking: more than just greasing the transport machinery | Q34499998 | ||
Role of the unfolded protein response pathway in secretory stress and regulation of INO1 expression in Saccharomyces cerevisiae | Q34569387 | ||
Role of the unfolded protein response pathway in regulation of INO1 and in the sec14 bypass mechanism in Saccharomyces cerevisiae. | Q34615963 | ||
The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane | Q34673029 | ||
New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c | Q34682304 | ||
The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response | Q35029280 | ||
Ca2+ signaling and calcium binding chaperones of the endoplasmic reticulum | Q35051255 | ||
Frame switch splicing and regulated intramembrane proteolysis: key words to understand the unfolded protein response | Q35168508 | ||
Translational control of C/EBPalpha and C/EBPbeta isoform expression. | Q35199785 | ||
Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress | Q35221396 | ||
Transport of proteins across the endoplasmic reticulum membrane | Q35235780 | ||
Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents | Q36183590 | ||
PKR and eIF2alpha: integration of kinase dimerization, activation, and substrate docking | Q36265197 | ||
XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. | Q36322684 | ||
Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis | Q36557194 | ||
Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes | Q36698641 | ||
Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae | Q36768641 | ||
ChREBP, a transcriptional regulator of glucose and lipid metabolism | Q36788526 | ||
Dissection of endoplasmic reticulum stress signaling in alcoholic and non-alcoholic liver injury | Q36800154 | ||
Cholesterol feeding reduces nuclear forms of sterol regulatory element binding proteins in hamster liver | Q36806480 | ||
Translational control and the unfolded protein response | Q36924278 | ||
Transmembrane bZIP transcription factors in ER stress signaling and the unfolded protein response | Q36948672 | ||
Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity | Q36981204 | ||
The recognition and retrotranslocation of misfolded proteins from the endoplasmic reticulum | Q37100233 | ||
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss | Q37105351 | ||
Feedback regulation of cholesterol synthesis: sterol-accelerated ubiquitination and degradation of HMG CoA reductase | Q37173755 | ||
Mice with a deletion in the gene for CCAAT/enhancer-binding protein beta are protected against diet-induced obesity | Q37178851 | ||
The endoplasmic reticulum stress response in immunity and autoimmunity | Q37231726 | ||
Real-time redox measurements during endoplasmic reticulum stress reveal interlinked protein folding functions | Q37335994 | ||
Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells | Q37364195 | ||
Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice | Q37375695 | ||
Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2. | Q37382401 | ||
Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice. | Q38311106 | ||
ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum | Q80935578 | ||
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1 | Q80979487 | ||
Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis | Q81441036 | ||
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation | Q28131669 | ||
EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome | Q28142981 | ||
Translational control is required for the unfolded protein response and in vivo glucose homeostasis | Q28204066 | ||
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor | Q28238069 | ||
Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis | Q28258427 | ||
The emergence of yeast lipidomics | Q28258926 | ||
Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum | Q28262304 | ||
ERAD: the long road to destruction | Q28264823 | ||
Protein folding and quality control in the endoplasmic reticulum | Q28272791 | ||
Proteolytic activation of sterol regulatory element-binding protein induced by cellular stress through depletion of Insig-1 | Q28276509 | ||
SREBP-1c transcription factor and lipid homeostasis: clinical perspective | Q28291930 | ||
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
Regulation of protein synthesis by heme-regulated eIF-2 alpha kinase | Q28299534 | ||
Tunicamycin induces ubiquitination and degradation of apolipoprotein B in HepG2 cells | Q28347626 | ||
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice | Q28359871 | ||
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways | Q28365886 | ||
The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas | Q28505821 | ||
Regulated translation initiation controls stress-induced gene expression in mammalian cells | Q28506388 | ||
Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes | Q28506402 | ||
PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation | Q28507769 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis | Q28508851 | ||
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum | Q28509611 | ||
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress | Q28511471 | ||
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha | Q28512201 | ||
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum | Q28512249 | ||
The transcription factor XBP-1 is essential for the development and survival of dendritic cells | Q28512302 | ||
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state | Q28572472 | ||
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis | Q28576685 | ||
A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver | Q28583240 | ||
c-Myc and ChREBP regulate glucose-mediated expression of the L-type pyruvate kinase gene in INS-1-derived 832/13 cells | Q28584276 | ||
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
An essential role in liver development for transcription factor XBP-1 | Q28593777 | ||
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival | Q28593963 | ||
ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response | Q28611502 | ||
The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response | Q28646118 | ||
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals | Q28646129 | ||
Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes | Q28646399 | ||
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress | Q29547441 | ||
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver | Q29547646 | ||
Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls | Q29547730 | ||
A central role for JNK in obesity and insulin resistance | Q29619778 | ||
Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus | Q29620179 | ||
PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice | Q33295459 | ||
Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response | Q33713564 | ||
The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis. | Q33777806 | ||
Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes | Q33878155 | ||
CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice | Q33943164 | ||
APOLIPOPROTEIN B: mRNA editing, lipoprotein assembly, and presecretory degradation | Q34001437 | ||
Lipid metabolism and regulation of membrane trafficking | Q34156587 | ||
On the mechanism of sensing unfolded protein in the endoplasmic reticulum | Q34230593 | ||
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation | Q34345459 | ||
Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1. | Q34451430 | ||
Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis | Q34497858 | ||
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice | Q38354947 | ||
Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2 | Q39315996 | ||
ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth | Q39470144 | ||
Intracellular retention of surface protein by a hepatitis B virus mutant that releases virion particles | Q39872988 | ||
Endoplasmic reticulum stress induces leptin resistance | Q39945899 | ||
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
Development of plaque assays for hepatitis C virus-JFH1 strain and isolation of mutants with enhanced cytopathogenicity and replication capacity | Q40065076 | ||
Activation of the ER stress gene gadd153 by hepatitis C virus sensitizes cells to oxidant injury | Q40157434 | ||
Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes | Q40176269 | ||
Hepatitis B virus X protein (HBx) activates ATF6 and IRE1-XBP1 pathways of unfolded protein response | Q40210691 | ||
Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis | Q40294776 | ||
Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells | Q40313352 | ||
Glucose activation of ChREBP in hepatocytes occurs via a two-step mechanism | Q40336619 | ||
Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion | Q40421534 | ||
Glucosamine-induced endoplasmic reticulum stress promotes ApoB100 degradation: evidence for Grp78-mediated targeting to proteasomal degradation. | Q40477226 | ||
Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress | Q40527936 | ||
Human CCAAT/enhancer-binding protein beta gene expression is activated by endoplasmic reticulum stress through an unfolded protein response element downstream of the protein coding sequence | Q40563931 | ||
Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response | Q40590374 | ||
The modification and assembly of proteins in the endoplasmic reticulum | Q40619093 | ||
P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. | Q41142872 | ||
Regulation of the expression of lipogenic enzyme genes by carbohydrate | Q41548602 | ||
Genome-wide analysis reveals inositol, not choline, as the major effector of Ino2p-Ino4p and unfolded protein response target gene expression in yeast | Q42010811 | ||
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance | Q42254249 | ||
ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress | Q42518206 | ||
Phosphorylation of eIF2 directs ATF5 translational control in response to diverse stress conditions | Q42523594 | ||
Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis. | Q42832143 | ||
Regulation of sterol regulatory-element binding protein 1 gene expression in liver: role of insulin and protein kinase B/cAkt | Q42996869 | ||
Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes. | Q42997321 | ||
Activation of endoplasmic reticulum stress response by hepatitis viruses up-regulates protein phosphatase 2A. | Q43037981 | ||
Wolcott-Rallison syndrome: pathogenic insights into neonatal diabetes from new mutation and expression studies of EIF2AK3. | Q43073998 | ||
Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice. | Q43778752 | ||
Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c | Q43848640 | ||
Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER. | Q44317091 | ||
The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages | Q44542540 | ||
Involvement of endoplasmic reticulum stress in insulin resistance and diabetes | Q45127777 | ||
Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response. | Q45345766 | ||
Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding model | Q46243875 | ||
Prevalence and mechanisms of hyperhomocysteinemia in chronic alcoholics | Q46565148 | ||
Blood glucose-lowering nuclear receptor agonists only partially normalize hepatic gene expression in db/db mice | Q46783954 | ||
ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver | Q50336015 | ||
PERK is essential for neonatal skeletal development to regulate osteoblast proliferation and differentiation. | Q51951390 | ||
PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis. | Q52000258 | ||
Targeted disruption of ATF4 discloses its essential role in the formation of eye lens fibres. | Q52178375 | ||
In situ hybridization studies suggest a role for the basic region‐leucine zipper protein hXBP‐1 in exocrine gland and skeletal development during mouse embryogenesis | Q52224944 | ||
Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver | Q57016669 | ||
Microphthalmia due to p53-mediated apoptosis of anterior lens epithelial cells in mice lacking the CREB-2 transcription factor | Q73967308 | ||
Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response | Q74359929 | ||
Genetic regulation of phospholipid metabolism: yeast as a model eukaryote | Q77347125 | ||
Overproduction of the Opi1 repressor inhibits transcriptional activation of structural genes required for phospholipid biosynthesis in the yeast Saccharomyces cerevisiae | Q78004043 | ||
Multiple endoplasmic reticulum-to-nucleus signaling pathways coordinate phospholipid metabolism with gene expression by distinct mechanisms | Q79733627 | ||
Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2 | Q80553475 | ||
P433 | issue | 17 | |
P304 | page(s) | 2835-2850 | |
P577 | publication date | 2009-05-26 | |
P1433 | published in | Cellular and Molecular Life Sciences | Q5058352 |
P1476 | title | Intersection of the unfolded protein response and hepatic lipid metabolism | |
P478 | volume | 66 |
Q47722752 | Activation of the Integrated Stress Response and Metabolic Dysfunction in a Murine Model of Sleep Apnea |
Q36230913 | Adiponectin suppresses endoplasmic reticulum stress in nonalcoholic steatohepatitis |
Q33858526 | Apolipoprotein B100 quality control and the regulation of hepatic very low density lipoprotein secretion. |
Q39640835 | Bip overexpression, but not CHOP inhibition, attenuates fatty-acid-induced endoplasmic reticulum stress and apoptosis in HepG2 liver cells |
Q98612728 | Celecoxib attenuates hepatocyte apoptosis by inhibiting endoplasmic reticulum stress in thioacetamide-induced cirrhotic rats |
Q37863134 | Cell death and nonalcoholic steatohepatitis: where is ballooning relevant? |
Q39871337 | Cholesterol and nonalcoholic fatty liver disease: renewed focus on an old villain |
Q37990529 | Clock genes and clock-controlled genes in the regulation of metabolic rhythms |
Q39305244 | Defining the momiome: Promiscuous information transfer by mobile mitochondria and the mitochondrial genome |
Q90272970 | Different protein expression patterns in rat spinal nerves during Wallerian degeneration assessed using isobaric tags for relative and absolute quantitation proteomics profiling |
Q34166238 | Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance. |
Q69394578 | Do inositol supplements enhance phosphatidylinositol supply and thus support endoplasmic reticulum function? |
Q35008217 | Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion |
Q36507568 | Effect of Cudrania tricuspidata and Kaempferol in Endoplasmic Reticulum Stress-Induced Inflammation and Hepatic Insulin Resistance in HepG2 Cells |
Q36119922 | Endoplasmic Reticulum Stress-Related Genes in Yellow Catfish Pelteobagrus fulvidraco: Molecular Characterization, Tissue Expression, and Expression Responses to Dietary Copper Deficiency and Excess |
Q37834712 | Endoplasmic reticulum stress and lipid dysregulation |
Q35614922 | Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential |
Q30455973 | Endoplasmic reticulum stress plays a pivotal role in cell death mediated by the pan-deacetylase inhibitor panobinostat in human hepatocellular cancer cells |
Q37426801 | Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been |
Q52649427 | Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2). |
Q35213294 | Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress |
Q35617662 | High-Density Lipoprotein Prevents Endoplasmic Reticulum Stress-Induced Downregulation of Liver LOX-1 Expression |
Q35760821 | IRE1α activation protects mice against acetaminophen-induced hepatotoxicity |
Q34988108 | Induction of the unfolded protein response drives enhanced metabolism and chemoresistance in glioma cells |
Q48380334 | Ire1α in Pomc Neurons Is Required for Thermogenesis and Glycemia |
Q34797602 | Ischemic preconditioning induces autophagy and limits necrosis in human recipients of fatty liver grafts, decreasing the incidence of rejection episodes. |
Q48087919 | Lack of activation of the unfolded protein response in mouse and cellular models of Niemann-Pick type C disease. |
Q37070333 | Liver and diabetes. A vicious circle |
Q36850321 | Microsomal triglyceride transfer protein inhibition induces endoplasmic reticulum stress and increases gene transcription via Ire1α/cJun to enhance plasma ALT/AST |
Q38076705 | Minireview: endoplasmic reticulum stress: control in protein, lipid, and signal homeostasis. |
Q36102239 | Oxidative Stress and the ER Stress Response in a Murine Model for Early-Stage Alcoholic Liver Disease |
Q36004816 | Peroxisome deficiency-induced ER stress and SREBP-2 pathway activation in the liver of newborn PEX2 knock-out mice |
Q36196818 | Protein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3α/β regulate foam cell formation |
Q39396098 | Regulating Secretory Proteostasis through the Unfolded Protein Response: From Function to Therapy |
Q64111465 | Role of Endoplasmic Reticulum Stress in the Anticancer Activity of Natural Compounds |
Q36330343 | Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice. |
Q34141006 | The Role of Endoplasmic Reticulum Stress in the Progression of Atherosclerosis |
Q37412003 | The adaptive endoplasmic reticulum stress response to lipotoxicity in progressive human nonalcoholic fatty liver disease |
Q37867697 | The mechanistic basis for the induction of hepatic steatosis by xenobiotics |
Q27933904 | The membrane stress response buffers lethal effects of lipid disequilibrium by reprogramming the protein homeostasis network |
Q37804621 | The unfolded protein response in lung disease |
Q28589300 | Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis |
Q42559592 | Tumor progression locus 2 ablation suppressed hepatocellular carcinoma development by inhibiting hepatic inflammation and steatosis in mice |
Q36802015 | Vitamin C modulates the metabolic and cytokine profiles, alleviates hepatic endoplasmic reticulum stress, and increases the life span of Gulo-/- mice |
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