Protein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3α/β regulate foam cell formation

scientific article

Protein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3α/β regulate foam cell formation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1194/JLR.M051094
P932PMC publication ID4617134
P698PubMed publication ID25183803

P50authorCameron S McAlpineQ85094098
P2093author name stringGeoff H Werstuck
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Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP.Q30488194
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Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell linesQ40125072
Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosisQ40294776
Lipopolysaccharide-induced production of interleukin-10 is promoted by the serine/threonine kinase Akt.Q40355768
Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcriptionQ40372631
Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3.Q40483325
The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3.Q40970988
Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.Q42431545
Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stressQ42451739
Chronic endoplasmic reticulum stress activates unfolded protein response in arterial endothelium in regions of susceptibility to atherosclerosis.Q42559927
Palmitate modulates intracellular signaling, induces endoplasmic reticulum stress, and causes apoptosis in mouse 3T3-L1 and rat primary preadipocytesQ42828051
Atherosclerosis induced by a high-fat diet is alleviated by lithium chloride via reduction of VCAM expression in ApoE-deficient miceQ42871419
Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activationQ44135113
Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithiumQ44264546
Examining the correlations between GSK-3 inhibitory properties and anti-convulsant efficacy of valproate and valproate-related compoundsQ45105674
Evidence supporting a role for endoplasmic reticulum stress in the development of atherosclerosis in a hyperglycaemic mouse model.Q45953764
IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C. elegans.Q46024898
Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient miceQ46421418
Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosisQ46434986
Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolismQ46972415
Endoplasmic reticulum stress and glycogen synthase kinase-3β activation in apolipoprotein E-deficient mouse models of accelerated atherosclerosis.Q51402296
ATF4 regulates lipid metabolism and thermogenesisQ82468721
Glucosamine-supplementation promotes endoplasmic reticulum stress, hepatic steatosis and accelerated atherogenesis in apoE-/- miceQ84798239
P4510describes a project that usesImageJQ1659584
P433issue11
P921main subjectendoplasmic reticulumQ79927
P304page(s)2320-2333
P577publication date2014-09-02
P1433published inJournal of Lipid ResearchQ6295449
P1476titleProtein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3α/β regulate foam cell formation
P478volume55

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cites work (P2860)
Q38739223Activation of endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance of human small cell lung cancer cells by inhibiting the PI3K/AKT/mTOR signaling pathway
Q36627711Dietary Cocoa Powder Improves Hyperlipidemia and Reduces Atherosclerosis in apoE Deficient Mice through the Inhibition of Hepatic Endoplasmic Reticulum Stress
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Q54977618The Role of Endoplasmic Reticulum Stress-Glycogen Synthase Kinase-3 Signaling in Atherogenesis.
Q92166012Unfolded Protein Response as a Therapeutic Target in Cardiovascular Disease
Q44964898Unfolded protein response signaling impacts macrophage polarity to modulate breast cancer cell clearance and melanoma immune checkpoint therapy responsiveness

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