scholarly article | Q13442814 |
P2093 | author name string | Takashi Sato | |
Kazutoshi Mori | |||
Keisuke Yamamoto | |||
Seiichi Oyadomari | |||
Tetsuya Okada | |||
Akihiro Harada | |||
Kazuna Takahara | |||
P2860 | cites work | Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 |
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta | Q22011091 | ||
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs | Q24290776 | ||
Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response | Q24290935 | ||
Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response | Q24534422 | ||
Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response | Q24548363 | ||
Nonalcoholic fatty liver disease | Q24555779 | ||
The blind men 'see' the elephant-the many faces of fatty liver disease | Q24654991 | ||
Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. | Q24815740 | ||
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION | Q25939000 | ||
Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
Protein synthesis upon acute nutrient restriction relies on proteasome function | Q40336957 | ||
The surface of lipid droplets is a phospholipid monolayer with a unique Fatty Acid composition | Q40705151 | ||
Degradation of newly synthesized apolipoprotein B-100 in a pre-Golgi compartment | Q41728130 | ||
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress | Q42518206 | ||
Developmental changes of synapsin I subcellular localization in rat cerebellar neurons | Q48849020 | ||
Regulated Co-translational ubiquitination of apolipoprotein B100. A new paradigm for proteasomal degradation of a secretory protein | Q56971926 | ||
Intrahepatic assembly of very low density lipoproteins. Rate of transport out of the endoplasmic reticulum determines rate of secretion | Q69447815 | ||
The apolipoprotein B gene is constitutively expressed in HepG2 cells: regulation of secretion by oleic acid, albumin, and insulin, and measurement of the mRNA half-life | Q69543027 | ||
CuZn-SOD deficiency causes ApoB degradation and induces hepatic lipid accumulation by impaired lipoprotein secretion in mice | Q80142989 | ||
ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum | Q80935578 | ||
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1 | Q80979487 | ||
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation | Q28131669 | ||
CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription | Q28287446 | ||
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways | Q28365886 | ||
Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload | Q28506232 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum | Q28509611 | ||
Dynamic and regulated association of caveolin with lipid bodies: modulation of lipid body motility and function by a dominant negative mutant | Q28581882 | ||
ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response | Q28611502 | ||
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals | Q28646129 | ||
The mammalian unfolded protein response | Q29547400 | ||
Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls | Q29547730 | ||
Steatohepatitis: a tale of two "hits"? | Q29547771 | ||
Lipid droplets: a unified view of a dynamic organelle | Q29614467 | ||
Molecular mediators of hepatic steatosis and liver injury | Q29616709 | ||
Molecular chaperones and protein quality control | Q29617795 | ||
Protein disulfide isomerase: the multifunctional redox chaperone of the endoplasmic reticulum | Q33794232 | ||
Tripartite management of unfolded proteins in the endoplasmic reticulum | Q33941135 | ||
A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6. | Q34202341 | ||
Activation of mammalian unfolded protein response is compatible with the quality control system operating in the endoplasmic reticulum | Q34358672 | ||
Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation | Q34512108 | ||
Mechanisms of non-alcoholic steatohepatitis | Q34554507 | ||
Retro-translocation of proteins from the endoplasmic reticulum into the cytosol | Q34627241 | ||
Complexity in the secretory pathway: the assembly and secretion of apolipoprotein B-containing lipoproteins | Q34634838 | ||
HRD gene dependence of endoplasmic reticulum-associated degradation | Q34711814 | ||
Pathogenesis of steatohepatitis | Q34983506 | ||
Nonalcoholic steatohepatitis: what we know in the new millennium | Q34993711 | ||
HSP47 as a collagen-specific molecular chaperone: function and expression in normal mouse development | Q35676791 | ||
The role of p58IPK in protecting the stressed endoplasmic reticulum | Q35949048 | ||
Lipid metabolism and liver inflammation. I. Hepatic fatty acid uptake: possible role in steatosis. | Q36366205 | ||
Mouse models in non-alcoholic fatty liver disease and steatohepatitis research. | Q36377266 | ||
Diversity of endotoxin and its impact on pathogenesis | Q36585994 | ||
PPARalpha and dyslipidemia | Q36866428 | ||
Nonalcoholic fatty liver disease and mitochondrial dysfunction | Q37054354 | ||
Transcriptional regulation of peroxisome proliferator-activated receptors and liver X receptors. | Q37074308 | ||
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
P433 | issue | 17 | |
P921 | main subject | endoplasmic reticulum | Q79927 |
pharmacology | Q128406 | ||
steatosis | Q1365091 | ||
knockout mouse | Q1364740 | ||
P304 | page(s) | 2975-2986 | |
P577 | publication date | 2010-07-14 | |
P1433 | published in | Molecular Biology of the Cell | Q2338259 |
P1476 | title | Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress | |
P478 | volume | 21 |
Q42824021 | A protective role for CD154 in hepatic steatosis in mice |
Q33819901 | ATF6 mediates a pro-inflammatory synergy between ER stress and TLR activation in the pathogenesis of liver ischemia-reperfusion injury |
Q36803184 | ATF6α/β-mediated adjustment of ER chaperone levels is essential for development of the notochord in medaka fish |
Q57065820 | Acinar cell injury induced by inadequate unfolded protein response in acute pancreatitis |
Q28539163 | Activating transcription factor 6 is necessary and sufficient for alcoholic fatty liver disease in zebrafish |
Q41764630 | Activating transcription factor 6 plays protective and pathological roles in steatosis due to endoplasmic reticulum stress in zebrafish |
Q35478792 | Alcohol disrupts endoplasmic reticulum function and protein secretion in hepatocytes |
Q37844233 | Animal models in the study of the unfolded protein response. |
Q91329630 | Browning of white adipose tissue after a burn injury promotes hepatic steatosis and dysfunction |
Q36596344 | C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liver |
Q47860370 | CNPY2 is a key initiator of the PERK-CHOP pathway of the unfolded protein response |
Q38241810 | Cellular mechanisms of endoplasmic reticulum stress signaling in health and disease. 1. An overview. |
Q91691395 | Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresponsiveness by inhibiting UPR transducers |
Q47813504 | Coordinating Organismal Metabolism During Protein Misfolding in the ER Through the Unfolded Protein Response |
Q39390726 | Curcumin ameliorates streptozotocin-induced liver damage through modulation of endoplasmic reticulum stress-mediated apoptosis in diabetic rats |
Q28468698 | Defining hepatic dysfunction parameters in two models of fatty liver disease in zebrafish larvae |
Q42724914 | Dietary Zinc Regulates Apoptosis through the Phosphorylated Eukaryotic Initiation Factor 2α/Activating Transcription Factor-4/C/EBP-Homologous Protein Pathway during Pharmacologically Induced Endoplasmic Reticulum Stress in Livers of Mice. |
Q64094472 | Differential regulation of the unfolded protein response in outbred deer mice and susceptibility to metabolic disease |
Q35709954 | Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice |
Q36507547 | Docosahexaenoic Acid Ameliorates Fructose-Induced Hepatic Steatosis Involving ER Stress Response in Primary Mouse Hepatocytes |
Q57629429 | Dropping in on lipid droplets: insights into cellular stress and cancer |
Q50968208 | ER Stress Inhibits Liver Fatty Acid Oxidation while Unmitigated Stress Leads to Anorexia-Induced Lipolysis and Both Liver and Kidney Steatosis. |
Q35779442 | ER Stress and Lipid Metabolism in Adipocytes |
Q91808662 | ER Stress and Unfolded Protein Response in Cancer Cachexia |
Q42355577 | ER Stress-induced Inflammasome Activation Contributes to Hepatic Inflammation and Steatosis |
Q33620277 | ER stress and hepatic lipid metabolism |
Q47295145 | ER stress in skeletal muscle remodeling and myopathies |
Q36777229 | ER stress: Autophagy induction, inhibition and selection. |
Q91658827 | Elevation of the unfolded protein response increases RANKL expression |
Q40394811 | Endoplasmic Reticulum (ER) Stress Induces Sirtuin 1 (SIRT1) Expression via the PI3K-Akt-GSK3β Signaling Pathway and Promotes Hepatocellular Injury |
Q37618082 | Endoplasmic Reticulum Stress and Related Pathological Processes |
Q48312436 | Endoplasmic Reticulum Stress in Mice Increases Hepatic Expression of Genes Carrying a Premature Termination Codon via a Nutritional Status-Independent GRP78-Dependent Mechanism |
Q38557011 | Endoplasmic reticulum stress and Oxidative stress in the pathogenesis of Non-alcoholic fatty liver disease |
Q35928460 | Endoplasmic reticulum stress and inflammation: mechanisms and implications in diabetic retinopathy |
Q35614922 | Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential |
Q97522970 | Endoplasmic reticulum stress and liver diseases |
Q34005691 | Endoplasmic reticulum stress and the unfolded protein responses in retinal degeneration |
Q34885351 | Endoplasmic reticulum stress in adipose tissue augments lipolysis |
Q45200756 | Endoplasmic reticulum stress induces hepatic steatosis via increased expression of the hepatic very low-density lipoprotein receptor |
Q28818754 | Experimental reconstitution of chronic ER stress in the liver reveals feedback suppression of BiP mRNA expression |
Q34396839 | Fibroblast growth factor 21 is regulated by the IRE1α-XBP1 branch of the unfolded protein response and counteracts endoplasmic reticulum stress-induced hepatic steatosis |
Q51664532 | Genomics of human fatty liver disease reveal mechanistically linked lipid droplet-associated gene regulations in bland steatosis and nonalcoholic steatohepatitis. |
Q33836210 | Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle |
Q50319304 | Hepatic ZIP14-mediated zinc transport is required for adaptation to endoplasmic reticulum stress. |
Q36951181 | ILDR2: an endoplasmic reticulum resident molecule mediating hepatic lipid homeostasis |
Q33816259 | In vivo metabolic fingerprinting of neutral lipids with hyperspectral stimulated Raman scattering microscopy |
Q58800423 | Induction of Liver Steatosis in BAP31-Deficient Mice Burdened with Tunicamycin-Induced Endoplasmic Reticulum Stress |
Q35790896 | Inhibition of fatty acid oxidation enhances oxidative protein folding and protects hepatocytes from endoplasmic reticulum stress |
Q50280266 | Inhibition of mitochondrial β-oxidation by miR-107 promotes hepatic lipid accumulation and impairs glucose tolerance in vivo. |
Q48183802 | Inorganic arsenic causes fatty liver and interacts with ethanol to cause alcoholic liver disease in zebrafish |
Q37897618 | Is fat so bad? Modulation of endoplasmic reticulum stress by lipid droplet formation |
Q35027785 | KLF15 is a molecular link between endoplasmic reticulum stress and insulin resistance |
Q38303017 | Leptin induced GRP78 expression through the PI3K-mTOR pathway in neuronal cells |
Q42009740 | Levels of Hepatic Activating Transcription Factor 6 and Caspase-3 Are Downregulated in Mice after Excessive Training |
Q37157015 | Lipid droplets and cellular lipid metabolism |
Q39253589 | Lipid droplets and liver disease: from basic biology to clinical implications. |
Q29620447 | Mechanisms for insulin resistance: common threads and missing links |
Q95840450 | Mechanisms, regulation and functions of the unfolded protein response |
Q33814245 | Molecularly defined unfolded protein response subclasses have distinct correlations with fatty liver disease in zebrafish |
Q38999100 | NF-Y (CBF) regulation in specific cell types and mouse models |
Q37297058 | Netrin-1 Protects Hepatocytes Against Cell Death Through Sustained Translation During the Unfolded Protein Response |
Q38630243 | Non-alcoholic fatty liver disease in mice with heterozygous mutation in TMED2. |
Q61443337 | Nuclear lipid droplets derive from a lipoprotein precursor and regulate phosphatidylcholine synthesis |
Q41679663 | Omega-3 and alpha-tocopherol provide more protection against contaminants in novel feeds for Atlantic salmon (Salmo salar L.) than omega-6 and gamma tocopherol |
Q28084613 | Oxidative stress, unfolded protein response, and apoptosis in developmental toxicity |
Q52664254 | Paradoxical roles of ATF6α and ATF6β in modulating disease severity caused by mutations in collagen X. |
Q35907138 | Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model. |
Q35747483 | Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formation |
Q41583320 | Physiological/pathological ramifications of transcription factors in the unfolded protein response |
Q36408473 | Profiling impaired hepatic endoplasmic reticulum glycosylation as a consequence of ethanol ingestion |
Q36196818 | Protein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3α/β regulate foam cell formation |
Q28537663 | Rapid induction of lipid droplets in Chlamydomonas reinhardtii and Chlorella vulgaris by Brefeldin A |
Q98578238 | Redox Regulation of Metabolic Syndrome: Recent Developments in Skeletal Muscle Insulin Resistance and Non-alcoholic Fatty Liver Disease (NAFLD) |
Q38153592 | Regulatory crosstalk within the mammalian unfolded protein response |
Q38202220 | Revisiting the metabolic syndrome and paving the way for microRNAs in non-alcoholic fatty liver disease. |
Q26771256 | Role for the Unfolded Protein Response in Heart Disease and Cardiac Arrhythmias |
Q26765518 | Role of endoplasmic reticulum stress in drug-induced toxicity |
Q26853645 | Role of endoplasmic reticulum stress in the pathogenesis of nonalcoholic fatty liver disease |
Q54397189 | Role of the unfolded protein response in organ physiology: lessons from mouse models. |
Q38210545 | Role of the unfolded protein response in β cell compensation and failure during diabetes |
Q36497621 | Role of the unfolded protein response, GRP78 and GRP94 in organ homeostasis. |
Q37889805 | Secretory pathway stress responses as possible mechanisms of disease involving Golgi Ca2+ pump dysfunction |
Q60921870 | Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth |
Q27009277 | Stress management: How the unfolded protein response impacts fatty liver disease |
Q37512024 | Synthetic embryonic lethality upon deletion of the ER cochaperone p58(IPK) and the ER stress sensor ATF6α |
Q38811934 | Targeting endoplasmic reticulum stress in liver disease. |
Q42970598 | Temporal clustering of gene expression links the metabolic transcription factor HNF4α to the ER stress-dependent gene regulatory network |
Q93078996 | The ER-localized Ca2+-binding protein calreticulin couples ER stress to autophagy by associating with microtubule-associated protein 1A/1B light chain 3 |
Q54945589 | The Effect of Amygdalin on Endoplasmic Reticulum (ER) Stress Induced Hepatic Steatosis in Mice. |
Q89965531 | The Emerging Roles of Endoplasmic Reticulum Stress in Balancing Immunity and Tolerance in Health and Diseases: Mechanisms and Opportunities |
Q26776377 | The Role of Organelle Stresses in Diabetes Mellitus and Obesity: Implication for Treatment |
Q35551757 | The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress. |
Q92775254 | The effects of endoplasmic reticulum stressors, tunicamycin and dithiothreitol on Trypanosoma cruzi |
Q38201042 | The essential biology of the endoplasmic reticulum stress response for structural and computational biologists. |
Q97643130 | The food contaminant deoxynivalenol provokes metabolic impairments resulting in non-alcoholic fatty liver (NAFL) in mice |
Q36062081 | The impact of the unfolded protein response on human disease |
Q26795725 | The lipid droplet-a well-connected organelle |
Q38825911 | The role of ER stress in lipid metabolism and lipotoxicity |
Q38093057 | The role of the unfolded protein response in diabetes mellitus |
Q35981133 | The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells. |
Q38162132 | The unfolded protein response in fatty liver disease |
Q26797409 | The unfolded protein response in multiple sclerosis |
Q26799511 | The unfolded protein response in neurodegenerative diseases: a neuropathological perspective |
Q50026168 | The unfolded protein response regulator ATF6 promotes mesodermal differentiation. |
Q29615499 | The unfolded protein response: controlling cell fate decisions under ER stress and beyond |
Q37080357 | Transcriptional cross talk between orphan nuclear receptor ERRγ and transmembrane transcription factor ATF6α coordinates endoplasmic reticulum stress response. |
Q45733123 | Translocation of CIDEC in hepatocytes depends on fatty acids |
Q29248711 | Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer |
Q60950073 | Tunicamycin-Induced ER Stress is Accompanied with Oxidative Stress via Abrogation of Sulfur Amino Acids Metabolism in the Liver |
Q35181178 | Tunicamycin-induced unfolded protein response in the developing mouse brain |
Q50988843 | Ultrastructure of Cell Organelles in Pre-implantation Embryos from Cows with Different Body Condition Score. |
Q55411030 | Unveiling “Musica Universalis” of the Cell: A Brief History of Biological 12-Hour Rhythms. |
Q57044814 | XBP1-KLF9 Axis Acts as a Molecular Rheostat to Control the Transition from Adaptive to Cytotoxic Unfolded Protein Response |
Q38291938 | XBP1s Is an Anti-lipogenic Protein |
Q26998690 | Xenobiotic perturbation of ER stress and the unfolded protein response |
Q26796338 | Zebrafish: an important tool for liver disease research |
Search more.