scholarly article | Q13442814 |
P50 | author | Jeanette N. McClintick | Q56055103 |
Tracy G. Anthony | Q54457113 | ||
P2093 | author name string | Ronald C Wek | |
Sheree A Wek | |||
Brian F Teske | |||
Judy K Cundiff | |||
Piyawan Bunpo | |||
P2860 | cites work | Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 |
Microphthalmia due to p53-mediated apoptosis of anterior lens epithelial cells in mice lacking the CREB-2 transcription factor | Q73967308 | ||
ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum | Q80935578 | ||
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1 | Q80979487 | ||
Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II | Q81144490 | ||
Phosphorylation of the alpha-subunit of the eukaryotic initiation factor-2 (eIF2alpha) reduces protein synthesis and enhances apoptosis in response to proteasome inhibition | Q81347002 | ||
That which does not kill me makes me stronger: adapting to chronic ER stress | Q81405125 | ||
ER stress signaling by regulated proteolysis of ATF6 | Q81604029 | ||
Methods for analyzing eIF2 kinases and translational control in the unfolded protein response | Q83296083 | ||
ATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligase | Q24290903 | ||
Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response | Q24290935 | ||
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress | Q24292499 | ||
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response | Q24304232 | ||
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease | Q24633352 | ||
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
Divergent effects of PERK and IRE1 signaling on cell viability | Q27438124 | ||
The structure of the PERK kinase domain suggests the mechanism for its activation | Q27667715 | ||
Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins | Q27932183 | ||
Regulation of translation initiation in eukaryotes: mechanisms and biological targets | Q28111696 | ||
Perk is essential for translational regulation and cell survival during the unfolded protein response | Q28140062 | ||
Transport-dependent proteolysis of SREBP: relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi | Q28141775 | ||
EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome | Q28142981 | ||
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
More powerful procedures for multiple significance testing | Q28255714 | ||
Wolcott-Rallison Syndrome: clinical, genetic, and functional study of EIF2AK3 mutations and suggestion of genetic heterogeneity | Q28268714 | ||
The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas | Q28505821 | ||
Regulated translation initiation controls stress-induced gene expression in mammalian cells | Q28506388 | ||
PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation | Q28507769 | ||
Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response | Q28508156 | ||
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum | Q28512249 | ||
PERK eIF2alpha kinase regulates neonatal growth by controlling the expression of circulating insulin-like growth factor-I derived from the liver | Q28593775 | ||
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival | Q28593963 | ||
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals | Q28646129 | ||
Opposing roles for ATF6alpha and ATF6beta in endoplasmic reticulum stress response gene induction | Q28854565 | ||
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response | Q29547299 | ||
The mammalian unfolded protein response | Q29547400 | ||
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress | Q29547441 | ||
IRE1 signaling affects cell fate during the unfolded protein response | Q29615502 | ||
Proteasome inhibitors: valuable new tools for cell biologists | Q29620573 | ||
SNARE Protein Structure and Function | Q30336208 | ||
eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory | Q30586619 | ||
PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice | Q33295459 | ||
BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response | Q33631257 | ||
Regulation of basal cellular physiology by the homeostatic unfolded protein response | Q33886820 | ||
Molecular symbiosis of CHOP and C/EBP beta isoform LIP contributes to endoplasmic reticulum stress-induced apoptosis | Q33963803 | ||
PERK (EIF2AK3) regulates proinsulin trafficking and quality control in the secretory pathway | Q34024253 | ||
Coordination of ATF6-mediated transcription and ATF6 degradation by a domain that is shared with the viral transcription factor, VP16. | Q34120076 | ||
Wolcott-Rallison syndrome | Q34148057 | ||
On the mechanism of sensing unfolded protein in the endoplasmic reticulum | Q34230593 | ||
Toxicogenomics of endoplasmic reticulum stress inducer tunicamycin in the small intestine and liver of Nrf2 knockout and C57BL/6J mice | Q35740930 | ||
Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response | Q36322641 | ||
Endoplasmic reticulum stress signaling in disease | Q36610455 | ||
Translational control and the unfolded protein response | Q36924278 | ||
Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2. | Q36948959 | ||
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells | Q37309146 | ||
Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells | Q37388595 | ||
In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesicles | Q37394440 | ||
GCN2 protein kinase is required to activate amino acid deprivation responses in mice treated with the anti-cancer agent L-asparaginase. | Q37432106 | ||
XBP1: the last two decades | Q37649065 | ||
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response | Q38326929 | ||
Underglycosylation of ATF6 as a novel sensing mechanism for activation of the unfolded protein response. | Q38346445 | ||
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
Role of vesicle-associated syntaxin 5 in the assembly of pre-Golgi intermediates | Q41064399 | ||
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress | Q42451739 | ||
ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress | Q42518206 | ||
Role of disulfide bridges formed in the luminal domain of ATF6 in sensing endoplasmic reticulum stress | Q42952040 | ||
Dependence of site-2 protease cleavage of ATF6 on prior site-1 protease digestion is determined by the size of the luminal domain of ATF6. | Q45010270 | ||
Effects of the isoform-specific characteristics of ATF6 alpha and ATF6 beta on endoplasmic reticulum stress response gene expression and cell viability | Q45101812 | ||
Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response. | Q45345766 | ||
Beta testing the antioxidant function of eIF2alpha phosphorylation in diabetes prevention. | Q45936856 | ||
PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis. | Q52000258 | ||
P433 | issue | 22 | |
P921 | main subject | endoplasmic reticulum | Q79927 |
P304 | page(s) | 4390-4405 | |
P577 | publication date | 2011-09-14 | |
P1433 | published in | Molecular Biology of the Cell | Q2338259 |
P1476 | title | The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress | |
P478 | volume | 22 |
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